Alice Grace Pearson, Lindsay Sheila Macnaughton, Karen Hind
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Untrained males and females performed a single bout of leg-based resistance exercise and consumed a milk protein (MILK-PRO: <i>n</i> = 4 males, <i>n</i> = 8 females) or isoenergetic control (CON: <i>n</i> = 4 males, <i>n</i> = 8 females) supplement over 4 days post-exercise (17 doses total). Maximum strength was assessed ≥3 wk pre- and 72 and 168 h post-exercise, and measures of leg circumference, range of motion, muscle soreness, pressure-pain threshold (PPT), and serum creatine kinase concentration ([CK]) were conducted pre-, immediately post-, and 24, 48, 72, and 168 h post-exercise. Resistance exercise induced mild muscle damage that was not attenuated with MILK-PRO relative to CON. Peak increases in [CK] and reductions in PPT were greater in males compared with females. Changes in other markers were comparable between sexes. We conclude that moderate resistance exercise in naïve individuals induces muscle damage without compromising muscle strength. We support sex differences in EIMD and emphasize the need for further research with both sexes. Milk protein ingestion was not beneficial for recovery from EIMD, thus alternative management strategies should be investigated. 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引用次数: 0
摘要
牛奶蛋白是一种常见的运动后营养选择,以增强运动恢复和适应。运动期间摄入牛奶蛋白可以减轻运动引起的肌肉损伤(EIMD),这对未经训练的人来说是一种特别的风险。然而,大多数研究都是针对男性进行的,由于EIMD存在潜在的性别差异,因此需要对两性进行研究。这项平行组随机对照试验研究了牛奶蛋白摄入对EIMD恢复的影响。未经训练的雄性和雌性进行了一次基于腿部的阻力运动,并在运动后4天内(总共17次)摄入牛奶蛋白(milk - pro: n = 4男性,n = 8女性)或等能对照(CON: n = 4男性,n = 8女性)补充剂。在运动前≥3周、运动后72和168小时评估最大力量,并在运动前、运动后立即以及运动后24、48、72和168小时测量腿围、活动度、肌肉酸痛、压痛阈值(PPT)和血清肌酸激酶浓度(CK)。抗阻运动诱导轻度肌肉损伤,与con相比,MILK-PRO并没有减轻这种损伤。与女性相比,男性CK的峰值升高和PPT的峰值降低更大。其他指标的变化在性别之间具有可比性。我们得出结论,naïve个体的适度阻力运动诱导肌肉损伤而不损害肌肉力量。我们支持EIMD的性别差异,并强调需要进一步对两性进行研究。牛奶蛋白摄入不利于EIMD的恢复,因此应研究其他管理策略。该试验在ClinicalTrials.gov PRS前瞻性注册(协议ID: 290580A)。
Milk protein ingestion does not enhance recovery from muscle-damaging resistance exercise in untrained males and females: a randomized controlled trial.
Milk-based proteins are a common choice of post-exercise nutrition to enhance exercise recovery and adaptation. Peri-exercise milk protein ingestion may attenuate exercise-induced muscle damage (EIMD), which is a particular risk to untrained individuals. However, most research has been conducted with males, and due to potential sex differences in EIMD, research with both sexes is required. This parallel-group randomized controlled trial examined the impact of milk protein ingestion on recovery from EIMD. Untrained males and females performed a single bout of leg-based resistance exercise and consumed a milk protein (MILK-PRO: n = 4 males, n = 8 females) or isoenergetic control (CON: n = 4 males, n = 8 females) supplement over 4 days post-exercise (17 doses total). Maximum strength was assessed ≥3 wk pre- and 72 and 168 h post-exercise, and measures of leg circumference, range of motion, muscle soreness, pressure-pain threshold (PPT), and serum creatine kinase concentration ([CK]) were conducted pre-, immediately post-, and 24, 48, 72, and 168 h post-exercise. Resistance exercise induced mild muscle damage that was not attenuated with MILK-PRO relative to CON. Peak increases in [CK] and reductions in PPT were greater in males compared with females. Changes in other markers were comparable between sexes. We conclude that moderate resistance exercise in naïve individuals induces muscle damage without compromising muscle strength. We support sex differences in EIMD and emphasize the need for further research with both sexes. Milk protein ingestion was not beneficial for recovery from EIMD, thus alternative management strategies should be investigated. This trial was prospectively registered at ClinicalTrials.gov PRS (protocol ID: 290580A).
期刊介绍:
Applied Physiology, Nutrition, and Metabolism publishes original research articles, reviews, and commentaries, focussing on the application of physiology, nutrition, and metabolism to the study of human health, physical activity, and fitness. The published research, reviews, and symposia will be of interest to exercise physiologists, physical fitness and exercise rehabilitation specialists, public health and health care professionals, as well as basic and applied physiologists, nutritionists, and biochemists.