Annals of Surgical Treatment and Research最新文献_第5页

Lesson from COVID-19 outbreak; importance of standard precautions to febrile neutropenia prevention in patients with breast cancer who received adjuvant chemotherapy: a retrospective observational study. COVID-19疫情的教训；标准预防措施对预防接受辅助化疗的乳腺癌患者发热性中性粒细胞减少症的重要性：一项回顾性观察研究。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2024-10-01 Epub Date: 2024-09-30 DOI: 10.4174/astr.2024.107.4.195

Ji Eun Park, Jieun Yang, Sanghoon Han, Jeong Rae Yoo, Misun Kim, Donghyoun Lee, Jaemin Jo

{"title":"Lesson from COVID-19 outbreak; importance of standard precautions to febrile neutropenia prevention in patients with breast cancer who received adjuvant chemotherapy: a retrospective observational study.","authors":"Ji Eun Park, Jieun Yang, Sanghoon Han, Jeong Rae Yoo, Misun Kim, Donghyoun Lee, Jaemin Jo","doi":"10.4174/astr.2024.107.4.195","DOIUrl":"https://doi.org/10.4174/astr.2024.107.4.195","url":null,"abstract":"Purpose: Intensive cytotoxic chemotherapy increases the risk of infection in patients with cancer by inducing bone marrow suppression and mucosal injury. Febrile neutropenia (FN) is the most important clinical adverse event in patients with cancer receiving cytotoxic chemotherapy. To prevent FN, standard precautions including hand and respiratory hygiene are generally recommended, but the exact effect of non-pharmacologic intervention has not been clearly proven in the clinical setting. We aimed to compare the incidence of FN between the pre-coronavirus disease 19 (COVID-19) era vs. the post-COVID-19 era.Methods: We retrospectively enrolled patients with breast cancer who received an adriamycin and cyclophosphamide (AC) regimen containing adjuvant chemotherapy at Jeju National University Hospital. We compared the incidence of FN between the pre- and post-COVID-19 period and analyzed characteristics of the event and other clinical risk factors.Results: In total, 149 patients were enrolled, including 94 who received AC chemotherapy in the pre-COVID-19 era and 55 who received it in the post-COVID-19 era. Sixteen patients (10.7%) experienced FN. Fourteen (14.9%) and 2 events (3.6%) occurred in pre-COVID-19 and post-COVID-19 eras, respectively. The post-COVID-19 era was the only risk factor for FN (P = 0.032).Conclusion: We found an association between FN occurrence and the COVID-19 outbreak, providing indirect evidence of the importance of non-pharmacological measures to reduce FN risk in patients with breast cancer. Further research is required to confirm the standard precautions for FN prevention in patients with cancer.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"107 4","pages":"195-202"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11473323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early stage adrenocortical carcinoma-what contributes to poor prognosis after adrenalectomy? A retrospective cohort study. 早期肾上腺皮质癌--肾上腺切除术后预后不良的原因是什么？一项回顾性队列研究。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2024-10-01 Epub Date: 2024-09-30 DOI: 10.4174/astr.2024.107.4.187

Douk Kwon, Cheong-Sil Rah, Byung-Chang Kim, Shin Jeong Pak, Jae Won Cho, Won Woong Kim, Yu-Mi Lee, Jae Lyun Lee, Dong Eun Song, Ki-Wook Chung, Tae-Yon Sung

{"title":"Early stage adrenocortical carcinoma-what contributes to poor prognosis after adrenalectomy? A retrospective cohort study.","authors":"Douk Kwon, Cheong-Sil Rah, Byung-Chang Kim, Shin Jeong Pak, Jae Won Cho, Won Woong Kim, Yu-Mi Lee, Jae Lyun Lee, Dong Eun Song, Ki-Wook Chung, Tae-Yon Sung","doi":"10.4174/astr.2024.107.4.187","DOIUrl":"https://doi.org/10.4174/astr.2024.107.4.187","url":null,"abstract":"Purpose: Adrenocortical carcinoma (ACC) is a rare primary carcinoma originating in the adrenal gland with a poor prognosis and a high recurrence rate. This study evaluated the risk factors associated with recurrence in patients with early stage ACC after curative surgical resection.Methods: The present study retrospectively evaluated the risk factors for recurrence in 38 patients with stages 1 and 2 ACC who underwent curative resection between 1995 and 2020.Results: Recurrence was observed in 21 patients (55.3%), with no significant difference between stages 1 and 2 ACC (P = 0.640). The overall recurrence rate was higher in patients who underwent minimally invasive surgery than open adrenalectomy (71.4% vs. 51.6%). Of the 33 patients with gross tumor margins negative for malignancy, 16 (48.5%) experienced tumor recurrence, and all 5 patients with positive and unknown gross resection margins had recurrence. Recurrences were observed in 14 of the 30 patients (46.7%) negative for pathologic resection margins, 6 of the 7 patients (85.7%) with pathologically indeterminate margins, and 1 patient with pathologically positive margins.Conclusion: The recurrence rates are high even in patients with early stage ACC, being higher in patients who undergo minimally invasive surgery than open adrenalectomy. Obtaining clear resection margins during surgery may reduce tumor recurrence; however, gross or pathologic margin safety was not a secure factor in preventing recurrence. None of the factors analyzed was a definitive predictor of poor prognosis.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"107 4","pages":"187-194"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11473319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effects of sarcopenic obesity on immediate postoperative outcomes after pancreatoduodenectomy: a retrospective cohort study. 肌肉松弛性肥胖对胰十二指肠切除术后即刻疗效的影响：一项回顾性队列研究。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2024-10-01 Epub Date: 2024-09-30 DOI: 10.4174/astr.2024.107.4.203

Jae Hwan Jeong, Ji Su Kim, Seung-Seob Kim, Seung Soo Hong, Ho Kyoung Hwang, Chang Moo Kang, Hyoung-Il Kim, Kyung Sik Kim, Sung Hyun Kim

{"title":"The effects of sarcopenic obesity on immediate postoperative outcomes after pancreatoduodenectomy: a retrospective cohort study.","authors":"Jae Hwan Jeong, Ji Su Kim, Seung-Seob Kim, Seung Soo Hong, Ho Kyoung Hwang, Chang Moo Kang, Hyoung-Il Kim, Kyung Sik Kim, Sung Hyun Kim","doi":"10.4174/astr.2024.107.4.203","DOIUrl":"https://doi.org/10.4174/astr.2024.107.4.203","url":null,"abstract":"Purpose: Several studies have evaluated the impact of sarcopenic obesity (SO) on postoperative complications, including postoperative pancreatic fistula (POPF), in patients undergoing pancreatoduodenectomy (PD). Previous studies have shown that SO increases POPF, but it remains unclear whether SO increases postoperative complications. In this study, we aimed to determine the relationship between SO and immediate postoperative complications.Methods: From January 2005 to December 2019, the medical records of patients who underwent PD for periampullary cancer were retrospectively reviewed. Skeletal muscle index (SMI) and visceral fat area (VFA) were calculated from preoperative computed tomography images. Patients with high VFA were classified as obese, while those with low SMI were classified as sarcopenic. Patients were divided into 4 groups: normal group, sarcopenia only group, obesity only group, and SO group. Postoperative outcomes were compared between groups, and factors affecting postoperative complications were analyzed by multivariate analysis.Results: Normal group (n = 176), sarcopenia only group (n = 130), obesity only group (n = 207), and SO group (n = 117) were analyzed retrospectively. SO group had significantly more frequent major complications compared to the normal group (P = 0.006), as well as a significantly more frequent clinically relevant POPF compared to the other groups (P = 0.002). In multivariate analysis, SO was an independent risk factor for major complications (P = 0.008) and clinically relevant POPF (P = 0.003).Conclusion: SO is a factor associated with poor immediate postoperative outcomes after PD for periampullary cancer.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"107 4","pages":"203-211"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11473317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ERRATUM: Correction of the Conflict of Interest. Difference in prognostic impact of lateral pelvic lymph node metastasis between pre- and post-neoadjuvant chemoradiotherapy in rectal cancer patients. ERRATUM：利益冲突更正。直肠癌患者新辅助化放疗前后盆腔侧淋巴结转移对预后影响的差异。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2024-09-01 Epub Date: 2024-08-26 DOI: 10.4174/astr.2024.107.3.186

Byeo Lee Lim, In Ja Park, Young Il Kim, Chan Wook Kim, Jong Lyul Lee, Yong Sik Yoon, Seok-Byung Lim

引用次数: 0

Comparison of actual prognosis between unilateral and bilateral central neck dissection in modified radical neck dissection patients with no clinical central lymph node metastasis: a retrospective cohort study. 无临床中央淋巴结转移的改良根治性颈部清扫术患者单侧和双侧中央颈部清扫术实际预后的比较：一项回顾性队列研究。

IF 1.4 4区医学

Annals of Surgical Treatment and Research Pub Date : 2024-08-27 DOI: 10.4174/astr.2024.107.3.144

Kyorim Back,Jee Soo Kim,Jun-Ho Choe,Jung-Han Kim

{"title":"Comparison of actual prognosis between unilateral and bilateral central neck dissection in modified radical neck dissection patients with no clinical central lymph node metastasis: a retrospective cohort study.","authors":"Kyorim Back,Jee Soo Kim,Jun-Ho Choe,Jung-Han Kim","doi":"10.4174/astr.2024.107.3.144","DOIUrl":"https://doi.org/10.4174/astr.2024.107.3.144","url":null,"abstract":"PurposeThis study aimed to evaluate the long-term prognosis of contralateral central neck dissection (CND) in papillary thyroid cancer (PTC) patients with ipsilateral lateral neck metastasis. We compared the actual recurrence rate according to the extent of CND-ipsilateral and contralateral sides.MethodsA total of 708 PTC patients who underwent total thyroidectomy and concomitant ipsilateral or bilateral CND with ipsilateral lateral neck dissection between January 1997 and December 2022 at Samsung Medical Center were retrospectively analyzed.ResultsThe median follow-up time was 118 months. Locoregional recurrence was observed in 26 patients (7.9%) and 30 patients (7.9%) in the ipsilateral and bilateral CND groups, respectively. There were 6 contralateral recurrence cases (1.8%) in the ipsilateral CND group and 6 cases (1.6%) in the bilateral CND group. There was only 1 contralateral central neck recurrence in the ipsilateral CND group. The incidence of hypocalcemia (P = 0.007) was higher in the bilateral CND group compared to the ipsilateral CND group.ConclusionSurgeons may consider performing only unilateral CND-the side where tumor is for therapeutic purposes to reduce surgical complications.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"77 1","pages":"144-150"},"PeriodicalIF":1.4,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142269917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The outcomes of component separation technique versus no component separation technique in the repair of large ventral hernias and impact on quality of life: a multicenter retrospective cohort study. 大腹股沟疝修补术中组件分离技术与无组件分离技术的结果及其对生活质量的影响：一项多中心回顾性队列研究。

IF 1.4 4区医学

Annals of Surgical Treatment and Research Pub Date : 2024-08-26 DOI: 10.4174/astr.2024.107.3.178

Nail Omarov,Derya Salim Uymaz,Mesut Kaya

{"title":"The outcomes of component separation technique versus no component separation technique in the repair of large ventral hernias and impact on quality of life: a multicenter retrospective cohort study.","authors":"Nail Omarov,Derya Salim Uymaz,Mesut Kaya","doi":"10.4174/astr.2024.107.3.178","DOIUrl":"https://doi.org/10.4174/astr.2024.107.3.178","url":null,"abstract":"PurposeThis study aimed to compare the results of patients who underwent anterior component separation techniques (ACST) and those who did not undergo component separation techniques (non-CST) in complicated ventral hernia repairs (VHRs) and to investigate the effect of these techniques on quality of life (QoL).MethodsA total of 105 patients who were operated for large ventral hernias were retrospectively analyzed. The patients were divided into the ACST group (n = 48) and the non-CST group (n = 57). Demographic, intraoperative, and postoperative data were recorded. Postoperative follow-up was conducted at 2 and 4 weeks, and 6, 12, and 24 months. The primary and secondary outcomes and QoL were measured.ResultsThe female ratio was higher in both groups (P = 0.512). There was no significant difference between age and body mass index between the groups (P = 0.705 and P = 0.803). The mean defect size and mesh size were similar between the groups (P = 0.775 and P = 0.245). The mean operation duration and amount of blood loss were similar between the groups (P = 0.801 and P = 0.142). There was no statistically significant difference in the median visual analog scale scores between the groups (P = 0.551). During follow-up, only 3 patients (6.3%) in the ACST group and 4 patients (7.0%) in the non-CST group had recurrence. There was no significant difference in the short- and long-term QoL between the groups.ConclusionThe ACST is a feasible surgical option for patients with complicated VHRs. In addition, by improving QoL, the recurrence rate is similar to patients undergoing standard VHR.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"10 1","pages":"178-185"},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142264713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addressing the challenges of missed parathyroid glands in ultrasonography for secondary hyperparathyroidism: a retrospective observational study. 应对继发性甲状旁腺功能亢进症超声造影漏检甲状旁腺的挑战：一项回顾性观察研究。

IF 1.4 4区医学

Annals of Surgical Treatment and Research Pub Date : 2024-08-26 DOI: 10.4174/astr.2024.107.3.136

Shen-En Chou,Cheng-Hsi Yeh,Shun-Yu Chi,Fong-Fu Chou,Yi-Ju Wu,Yen-Hsiang Chang,Yi-Chia Chan

{"title":"Addressing the challenges of missed parathyroid glands in ultrasonography for secondary hyperparathyroidism: a retrospective observational study.","authors":"Shen-En Chou,Cheng-Hsi Yeh,Shun-Yu Chi,Fong-Fu Chou,Yi-Ju Wu,Yen-Hsiang Chang,Yi-Chia Chan","doi":"10.4174/astr.2024.107.3.136","DOIUrl":"https://doi.org/10.4174/astr.2024.107.3.136","url":null,"abstract":"PurposePreoperative localization plays an important role in secondary hyperparathyroidism (SHPT) surgery. The advantages of neck ultrasound (US) include high availability and low cost. However, the reported sensitivity of US is 54%-76%, and the reason for missed parathyroid glands (PGs) on US has been rarely addressed.MethodsFifty-four patients who were diagnosed with renal SHPT from September 2020 to March 2022 were included in this retrospective study. Preoperative localization included surgeon-oriented US and technetium 99m-sestamibi single-photon emission CT (SPECT)/CT.ResultsA total of 212 PGs were pathologically confirmed, resulting in a success rate of 96.2% (52 of 54). Using echo, 193 PGs (91.0%) were accurately localized, while 19 glands (9.0%) were not identified, including those in ectopic positions (n = 12, at thymus or intrathyroid or others), of small size (<1 cm, n = 6), or overlapping with an ipsilateral PG (n = 1). US accurately detected 4 PGs in 36 (66.7%) patients, while SPECT/CT localized 4 glands in 19 patients (35.2%). Although the number of US-detectable PGs was not associated with success rate, it showed a significant negative correlation with surgical time (rs = -0.459, P = 0.002).ConclusionUS detected 4 glands in 66% of SHPT patients with a sensitivity of 90% for localization. Ectopic position and small size were the most common reasons for the failure to detect PG on US. Complete preoperative echo localization might shorten operating time.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"32 1","pages":"136-143"},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142269915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The clinical effect of endoscopic and open surgery in the treatment of thyroid cancer and their effect on the blood coagulation state: a comparative study. 内窥镜手术和开放手术治疗甲状腺癌的临床效果及其对血液凝固状态的影响：一项比较研究。

IF 1.4 4区医学

Annals of Surgical Treatment and Research Pub Date : 2024-08-26 DOI: 10.4174/astr.2024.107.3.127

Qiyin Xu,Li Zhu,Weiping Chen,Weibin Peng

{"title":"The clinical effect of endoscopic and open surgery in the treatment of thyroid cancer and their effect on the blood coagulation state: a comparative study.","authors":"Qiyin Xu,Li Zhu,Weiping Chen,Weibin Peng","doi":"10.4174/astr.2024.107.3.127","DOIUrl":"https://doi.org/10.4174/astr.2024.107.3.127","url":null,"abstract":"PurposeThis study was performed to compare the therapeutic efficacy of endoscopic surgery and open surgery and their effects on postoperative blood coagulation state in patients with thyroid cancer, and to provide evidence for the prevention measurement of thrombosis in the perioperative period.MethodsOne hundred patients with thyroid cancer who received treatment in our hospital from January 2021 to December 2021, were randomly divided into an endoscopic group and an open surgery group, with 50 patients in each group. The patients in the open surgery group were treated by traditional open surgery, while patients in the endoscopic group accepted endoscopic surgery. The clinically therapeutic effect and blood coagulation of the 2 groups were compared.ResultsIntraoperative blood loss and length of hospital stay were lower, and operative time was longer in the endoscopic group than in the open surgery group (P < 0.05). The 24-hour postoperative fibrinogen and D-dimer levels were higher in both groups than in the preoperative period, while PT was shorter (P < 0.05). There were no significant differences in postoperative complications and follow-up between the 2 groups (P > 0.05), but the incidence of complications, postoperative metastases, and thrombosis was relatively low in the endoscopic group.ConclusionIn the treatment of patients with thyroid cancer, endoscopic surgery has the advantages of less blood loss, fewer complications, and so on. Endoscopic and open surgery can lead to a hypercoagulable state, but the effect of endoscopic surgery is better than that of open surgery.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"48 1","pages":"127-135"},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142264711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effective utilization of polypectomy in endoscopic salvage treatment of rectal neuroendocrine tumors: a retrospective cohort study. 在直肠神经内分泌肿瘤的内镜挽救治疗中有效利用息肉切除术：一项回顾性队列研究。

IF 1.4 4区医学

Annals of Surgical Treatment and Research Pub Date : 2024-08-26 DOI: 10.4174/astr.2024.107.3.151

Yeonuk Ju,Jun Woo Bong,Chinock Cheong,Sanghee Kang,Byung Wook Min,Sun Il Lee

{"title":"Effective utilization of polypectomy in endoscopic salvage treatment of rectal neuroendocrine tumors: a retrospective cohort study.","authors":"Yeonuk Ju,Jun Woo Bong,Chinock Cheong,Sanghee Kang,Byung Wook Min,Sun Il Lee","doi":"10.4174/astr.2024.107.3.151","DOIUrl":"https://doi.org/10.4174/astr.2024.107.3.151","url":null,"abstract":"PurposeCurrent guidelines recommend endoscopic resection for rectal neuroendocrine tumors (RNETs) under 10 mm. Incomplete resections necessitate salvage procedures, highlighting the need for complete R0 resection. This study evaluates the efficacy and safety of wide hot snare polypectomy (WHSP) compared to endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) for the salvage treatment of small RNETs.MethodsThis retrospective study was conducted at Korea University Guro Hospital from January 2018 to December 2022. It compared the outcomes of salvage resections for RNETs ≤10 mm using 2 approaches: ESD and EMR vs. WHSP. Demographics, tumor characteristics, and clinical outcomes were compared. Efficacy was evaluated by the histological complete resection rate and procedure time, while safety was assessed by the incidence of complications.ResultsOut of 135 patients undergoing salvage resection for RNET, 14 who underwent transanal excision were excluded. Of the remaining 121, 99 underwent EMR or ESD, and 22 underwent WHSP. Baseline characteristics were similar between the 2 groups. The WHSP group demonstrated a significantly higher R0 resection rate (72.7% vs. 49.5%, P = 0.010) and a shorter median procedure time (3.5 minutes vs. 8.3 minutes). No complications were reported in the WHSP group.ConclusionWHSP is a rapid, straightforward, safe, and effective approach for the salvage treatment of RNETs less than 10 mm in diameter, particularly in patients without additional risk factors.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"100 1","pages":"151-157"},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142264714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical significance and outcomes of adult living donor liver transplantation for acute liver failure: a retrospective cohort study based on 15-year single-center experience. 成人活体肝移植治疗急性肝功能衰竭的临床意义和疗效：基于 15 年单中心经验的回顾性队列研究。

IF 1.4 4区医学

Annals of Surgical Treatment and Research Pub Date : 2024-08-26 DOI: 10.4174/astr.2024.107.3.167

Geun-Hyeok Yang,Young-In Yoon,Shin Hwang,Ki-Hun Kim,Chul-Soo Ahn,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Dong-Hwan Jung,Gil-Chun Park,Sung-Gyu Lee

{"title":"Clinical significance and outcomes of adult living donor liver transplantation for acute liver failure: a retrospective cohort study based on 15-year single-center experience.","authors":"Geun-Hyeok Yang,Young-In Yoon,Shin Hwang,Ki-Hun Kim,Chul-Soo Ahn,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Dong-Hwan Jung,Gil-Chun Park,Sung-Gyu Lee","doi":"10.4174/astr.2024.107.3.167","DOIUrl":"https://doi.org/10.4174/astr.2024.107.3.167","url":null,"abstract":"PurposeThis study aimed to describe adult living donor liver transplantation (LDLT) for acute liver failure and evaluate its clinical significance by comparing its surgical and survival outcomes with those of deceased donor liver transplantation (DDLT).MethodsWe retrospectively reviewed the medical records of 267 consecutive patients (161 LDLT recipients and 106 DDLT recipients) aged 18 years or older who underwent liver transplantation between January 2006 and December 2020.ResultsThe mean periods from hepatic encephalopathy to liver transplantation were 5.85 days and 8.35 days for LDLT and DDLT, respectively (P = 0.091). Among these patients, 121 (45.3%) had grade III or IV hepatic encephalopathy (living, 34.8% vs. deceased, 61.3%; P < 0.001), and 38 (14.2%) had brain edema (living, 16.1% vs. deceased, 11.3%; P = 0.269) before liver transplantation. There were no significant differences in in-hospital mortality (living, 11.8% vs. deceased, 15.1%; P = 0.435), 10-year overall survival (living, 90.8% vs. deceased, 84.0%; P = 0.096), and graft survival (living, 83.5% vs. deceased, 71.3%; P = 0.051). However, postoperatively, the mean intensive care unit stay was shorter in the LDLT group (5.0 days vs. 9.5 days, P < 0.001). In-hospital mortality was associated with vasopressor use (odds ratio [OR], 3.40; 95% confidence interval [CI], 1.45-7.96; P = 0.005) and brain edema (OR, 2.75; 95% CI, 1.16-6.52; P = 0.022) of recipient at the time of transplantation. However, LDLT (OR, 1.26; 95% CI, 0.59-2.66; P = 0.553) was not independently associated with in-hospital mortality.ConclusionLDLT is feasible for acute liver failure when organs from deceased donors are not available.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"31 1","pages":"167-177"},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142264712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0