Annals of Surgical Treatment and Research最新文献_第5页

Appropriateness of multidisciplinary treatment related to the adequacy evaluation of gastric cancer from the surgeon's point of view: a retrospective cohort study. 从外科医生的角度评价胃癌的充分性是否适合多学科治疗：一项回顾性队列研究。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2025-04-01 Epub Date: 2025-03-31 DOI: 10.4174/astr.2025.108.4.240

Ba Ool Seong, Seul-Gi Oh, Chang Seok Ko, Sa-Hong Min, Chung Sik Gong, In-Seob Lee, Beom Su Kim, Jeong Hwan Yook, Moon-Won Yoo

{"title":"Appropriateness of multidisciplinary treatment related to the adequacy evaluation of gastric cancer from the surgeon's point of view: a retrospective cohort study.","authors":"Ba Ool Seong, Seul-Gi Oh, Chang Seok Ko, Sa-Hong Min, Chung Sik Gong, In-Seob Lee, Beom Su Kim, Jeong Hwan Yook, Moon-Won Yoo","doi":"10.4174/astr.2025.108.4.240","DOIUrl":"https://doi.org/10.4174/astr.2025.108.4.240","url":null,"abstract":"Purpose: Multidisciplinary treatment (MDT) in gastric cancer is an effective approach for establishing treatment plans. However, the appropriateness of using \"ratio of MDT\" as an item for evaluating the adequacy of gastric cancer treatment in Korea has not been previously researched. The purpose of this study is to verify whether the \"ratio of MDT\" is appropriate as an item for gastric cancer adequacy evaluation from the surgeon's perspective.Methods: This study involved 142 patients who received MDT at our hospital between December 2015 and January 2023. Patients were divided into 2 groups based on the date when gastric cancer adequacy evaluation was implemented; there were 71 patients before and after the evaluation was conducted, respectively. Based on electronic medical records, the initial plan prepared before the MDT clinic and the final plan prepared after the clinic were compared to determine whether the plan was changed.Results: The average age of patients who received MDT before and after the evaluation was 64.8 and 62.2 years, respectively. Overall, 50 and 21 patients were male (70.4%) and female (29.6%), respectively, in both groups. Before the evaluation, 26 patients (36.6%) who received MDT changed their treatment plans after visiting the clinic, and 15 patients (21.1%) who received MDT after the evaluation had their treatment plans modified. Groups who received MDT and changes in treatment plans were significantly correlated (P = 0.042).Conclusion: Our findings suggest that including the \"ratio of MDT\" as an item of gastric cancer adequacy evaluation needs reassessment.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 4","pages":"240-244"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nationwide big data analysis of inguinal hernia surgery trends in South Korea (2016-2022). 2016-2022年韩国腹股沟疝手术趋势大数据分析。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2025-04-01 Epub Date: 2025-03-31 DOI: 10.4174/astr.2025.108.4.211

Hyunjeong Ki, Seyoung Koo, Gil Ho Kang, Jiyoung Sul, Junbeom Park

{"title":"Nationwide big data analysis of inguinal hernia surgery trends in South Korea (2016-2022).","authors":"Hyunjeong Ki, Seyoung Koo, Gil Ho Kang, Jiyoung Sul, Junbeom Park","doi":"10.4174/astr.2025.108.4.211","DOIUrl":"https://doi.org/10.4174/astr.2025.108.4.211","url":null,"abstract":"Purpose: This study aimed to analyze nationwide trends and regional disparities in inguinal hernia surgeries in South Korea between 2016 and 2022. Additionally, we aimed to evaluate changes in surgery frequency, including urban concentration and the introduction of robotic surgery.Methods: This retrospective review used nationwide data on inguinal hernia surgeries from the Health Insurance Review and Assessment Service database.Results: From 2016 to 2022, 254,367 inguinal hernia surgeries were performed in South Korea, with males accounting for 88.9% of cases. The annual number of surgeries fluctuated, particularly in 2020, owing to the coronavirus disease 2019 pandemic. Medical costs increased from $1,218.4 to $1,970 on average, whereas patient copayments rose from $180.2 to $293.3. Robotic inguinal hernia surgeries, introduced in 2019, increased to 226 cases in 2022. Pediatric surgeries steadily declined, whereas adult surgeries remained stable, with a slight increase in 2022. The average hospital stay did not change significantly but varied between pediatric and adult patients. Regional disparities were notable, especially in pediatric surgery rates between metropolitan areas, such as Seoul and the surrounding provinces.Conclusion: This study highlights stable overall surgery rates, a decline in pediatric cases, and an increase in robotic inguinal hernia surgeries. The persistent concentration of healthcare services in metropolitan areas suggests a need for policy interventions to address regional disparities and ensure equitable healthcare access. The findings underscore the importance of ongoing efforts to improve healthcare distribution and the need for long-term strategies to address changing surgical trends.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 4","pages":"211-218"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sporopollenin-based material for prevention of postoperative adhesions: a murine study. 基于孢粉素的材料预防术后粘连：一项小鼠研究。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2025-04-01 Epub Date: 2025-03-31 DOI: 10.4174/astr.2025.108.4.256

Wei Beng Ng, Ian Ee En Sim, Wean Sin Cheow, Young Jun Chai

{"title":"Sporopollenin-based material for prevention of postoperative adhesions: a murine study.","authors":"Wei Beng Ng, Ian Ee En Sim, Wean Sin Cheow, Young Jun Chai","doi":"10.4174/astr.2025.108.4.256","DOIUrl":"https://doi.org/10.4174/astr.2025.108.4.256","url":null,"abstract":"Purpose: This study was performed to evaluate the antiadhesive effect and safety of a novel adhesion barrier device (ABD) in comparison to other commercially available anti-adhesion products.Methods: A 4-arm, controlled, blinded, experimental, and murine model study design was used. Forty male Sprague Dawley rats were randomly allocated to Interceed, Seprafilm, ABD, and control groups (n = 10/group). Abdominal cavity trauma was induced in all rats. Interceed, Seprafilm, or the ABD were applied to the injury site of each rat according to their respective groups, the control group received no intervention.Results: Twenty-one days after the operation, surgical adhesion severity and area scores were significantly reduced in the Interceed, Seprafilm, and ABD groups compared to the control group (P = 0.016, P < 0.001, P < 0.001, respectively), and in the ABD group compared to the Interceed group (P = 0.036). No significant difference was observed between the ABD and Seprafilm groups (P = 0.070). Additionally, in the ABD group, no remnants of the ABD were observed at the injury site, and no hematological abnormalities were present.Conclusion: The ABD has the potential to improve postsurgical peritoneal adhesions compared to Interceed and has comparable effectiveness compared to Seprafilm. The ABD may be a valuable option to reduce surgical failure. Further studies in human subjects are warranted to determine the clinical application and safety of the ABD for commercialization.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 4","pages":"256-269"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics of premenopausal breast cancer patients with a midrange 21-gene recurrence score. 绝经前乳腺癌患者的中期21基因复发评分特征。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2025-04-01 Epub Date: 2025-03-31 DOI: 10.4174/astr.2025.108.4.219

Jung Min Park, Suk Jun Lee, Jee Hyun Ahn, Chan Seok Yoon, Seho Park

{"title":"Characteristics of premenopausal breast cancer patients with a midrange 21-gene recurrence score.","authors":"Jung Min Park, Suk Jun Lee, Jee Hyun Ahn, Chan Seok Yoon, Seho Park","doi":"10.4174/astr.2025.108.4.219","DOIUrl":"https://doi.org/10.4174/astr.2025.108.4.219","url":null,"abstract":"Purpose: The results of the TAILORx trial have shown that premenopausal patients with intermediate Oncotype Dx (ODx) recurrence score of 16-25 may benefit from adjuvant chemotherapy. In addition, the clinicopathological features showed the information complementary to ODx results. However, the characteristics may vary depending on menopausal status even in the same score. This study aimed to analyze the differences in the clinical characteristics by menopausal status.Methods: This study conducted a retrospective analysis of 756 patients with estrogen receptor-positive, human epidermal growth factor receptor 2-negative, and node-negative breast cancer who underwent the ODx test from July 2013 to December 2020 at the Severance Hospital.Results: Of the 756 patients, 261 patients were postmenopausal, and 495 were premenopausal. The premenopausal patients with a midrange ODx had similar clinicopathological features as compared to those with a high ODx. Conversely, the postmenopausal patients with a midrange ODx did not show significantly different clinicopathological features from those with a low ODx, whereas a difference was seen as compared to those with a high ODx.Conclusion: In this study, unlike the postmenopausal patients, some of the clinicopathological characteristics of the premenopausal patients with a midrange ODx were closer to those with a high ODx than those with a low ODx. In the premenopausal patients with a midrange ODx, considering the baseline characteristic itself, there was a significant difference between those with a low ODx when compared with postmenopausal patients. Therefore, more aggressive treatment decisions may be helpful in premenopausal patients with a midrange ODx.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 4","pages":"219-230"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proposal of age definition for early-onset gastric cancer based on the Korean Gastric Cancer Association nationwide survey data: a retrospective observational study. 基于韩国胃癌协会全国调查数据的早发性胃癌年龄定义：回顾性观察性研究

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2025-04-01 Epub Date: 2025-03-31 DOI: 10.4174/astr.2025.108.4.245

Seong-A Jeong, Ji Sung Lee, Ba Ool Seong, Seul-Gi Oh, Chang Seok Ko, Sa-Hong Min, Chung Sik Gong, Beom Su Kim, Moon-Won Yoo, Jeong Hwan Yook, In-Seob Lee

{"title":"Proposal of age definition for early-onset gastric cancer based on the Korean Gastric Cancer Association nationwide survey data: a retrospective observational study.","authors":"Seong-A Jeong, Ji Sung Lee, Ba Ool Seong, Seul-Gi Oh, Chang Seok Ko, Sa-Hong Min, Chung Sik Gong, Beom Su Kim, Moon-Won Yoo, Jeong Hwan Yook, In-Seob Lee","doi":"10.4174/astr.2025.108.4.245","DOIUrl":"https://doi.org/10.4174/astr.2025.108.4.245","url":null,"abstract":"Purpose: This study aimed to define an optimal age cutoff for early-onset gastric cancer (EOGC) and compare its characteristics with those of late-onset gastric cancer (LOGC) using nationwide survey data.Methods: Using data from a nationwide survey, this comprehensive population-based study analyzed data spanning 3 years (2009, 2014, and 2019). The joinpoint analysis and interrupted time series (ITS) methodology were employed to identify age cutoffs for EOGC based on the sex ratio and tumor histology. Clinicopathologic characteristics and surgical outcomes were compared between the EOGC and LOGC groups.Results: The age cutoff for defining EOGC was suggested to be 50 years, supported by joinpoint and ITS analyses. Early gastric cancer was predominantly present in the EOGC and LOGC groups. Patients with EOGC comprised 20.3% of the total study cohort and demonstrated a more advanced disease stage compared to patients with LOGC. However, patients with EOGC underwent more minimally invasive surgeries, experienced shorter hospital stays, and had lower postoperative morbidity and mortality rates.Conclusion: This study proposes an age of ≤50 years as a criterion for defining EOGC and highlights its features compared to LOGC. Further research using this criterion should guide tailored treatment strategies and improve outcomes for young patients with gastric cancer.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 4","pages":"245-255"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

When her scalpels get stuck on the sticky floors: a qualitative study based on the experiences of female surgical faculty members in Korea. 当她的手术刀卡在黏糊糊的地板上时——以韩国女性外科医生的经历为基础的定性研究。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2025-04-01 Epub Date: 2025-03-31 DOI: 10.4174/astr.2025.108.4.199

Claire Junga Kim

{"title":"When her scalpels get stuck on the sticky floors: a qualitative study based on the experiences of female surgical faculty members in Korea.","authors":"Claire Junga Kim","doi":"10.4174/astr.2025.108.4.199","DOIUrl":"https://doi.org/10.4174/astr.2025.108.4.199","url":null,"abstract":"Purpose: This study explores the unique experiences and challenges faced by female surgical faculty members in Korea, particularly the transition from resident to faculty and the challenges that follow.Methods: Fifteen female surgeons from diverse surgical specialties, age groups, and medical institutions across Korea were recruited using snowball sampling. In-depth, semi-structured 1:1 interviews were conducted, recorded, and transcribed. Grounded theory was used to analyze the data, identifying recurring themes.Results: Four key themes emerged from the interviews: (1) Sticky floors and broken trail ropes: Female surgeons face a harsh, male-dominated environment with scarce resources for career advancement, often excluded from crucial networks. (2) Strategies: To cope with harsh environments, participants employed various strategies, including silent endurance, mobilizing external resources, exerting 'feminine' strength, and learning from the follies of others, or choosing not to use some of them. (3) Triumph and resentment: While participants experienced feelings of self-esteem and self-fulfillment as well as insight and flexibility, many also faced pressures of representation and burnout. (4) Building new resources: Participants sought to provide a system with enhanced transparency and fairness, a new network of support, and mentoring for future generations.Conclusion: This preliminary research demonstrates that female faculty members have overcome adversity; however, it also reveals that the challenges they face and their responses to them can act as risks that hinder their patient care and overall well-being, jeopardizing sustainability. Both the surgical field and the broader medical community must devote sufficient attention and resources to address this issue.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 4","pages":"199-210"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety and effectiveness of direct oral anticoagulants in fragile patients with venous thromboembolism: a retrospective cohort observational study. 静脉血栓栓塞患者直接口服抗凝剂的安全性和有效性：一项回顾性队列观察研究。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2025-03-01 Epub Date: 2025-02-28 DOI: 10.4174/astr.2025.108.3.168

Hojong Park, Sang Jun Park, Hyangkyoung Kim

{"title":"Safety and effectiveness of direct oral anticoagulants in fragile patients with venous thromboembolism: a retrospective cohort observational study.","authors":"Hojong Park, Sang Jun Park, Hyangkyoung Kim","doi":"10.4174/astr.2025.108.3.168","DOIUrl":"10.4174/astr.2025.108.3.168","url":null,"abstract":"Purpose: The use of direct oral anticoagulants (DOACs) is challenging in fragile patients, including those with cancer, chronic kidney disease (CKD), and old age. We aimed to compare the safety of DOACs in terms of bleeding complications in these patients.Methods: Using hospital data from 2013 to 2019, we compared the risk of bleeding and major bleeding, including intracranial bleeding, any bleeding requiring transfusion, and all-cause bleeding, in patients with venous thromboembolism (VTE) who were naïve to DOAC (n = 12,369) and warfarin (n = 4,123). Hazard ratios (HRs) for the clinical outcomes were analyzed using Cox regression analysis, with warfarin as a reference.Results: The study included 4,078 eligible patients, predominantly female (54.1%), with a mean age of 62.5 years. DOACs were the primary treatment in 74.1% of the patients. DOAC treatment was associated with lower all-cause mortality compared to warfarin (HR, 0.799; 95% confidence interval [CI], 0.707-0.904). Although rates of recurrent VTE or major bleeding did not significantly differ between the groups, DOAC-treated patients had lower bleeding risk (HR, 0.562; 95% CI, 0.393-0.805; P = 0.002). The individual DOAC drugs did not differ significantly in terms of composite outcomes, recurrence, or bleeding events.Conclusion: DOAC showed comparable outcomes with warfarin in the fragile patient population.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 3","pages":"168-176"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11896765/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic value of admission base excess in postoperative outcomes of aortic dissection patients: a retrospective cohort analysis. 入院基础过剩对主动脉夹层术后预后的预测价值：一项回顾性队列分析。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2025-03-01 Epub Date: 2025-02-28 DOI: 10.4174/astr.2025.108.3.158

Huanan Liu, Hua Lu, Xiaoshen Zhang

{"title":"Prognostic value of admission base excess in postoperative outcomes of aortic dissection patients: a retrospective cohort analysis.","authors":"Huanan Liu, Hua Lu, Xiaoshen Zhang","doi":"10.4174/astr.2025.108.3.158","DOIUrl":"10.4174/astr.2025.108.3.158","url":null,"abstract":"Purpose: The aim of this retrospective study was to evaluate the relationship between admission base excess and clinical outcomes in postoperative patients with aortic dissection.Methods: Clinical data were extracted from the MIMIC-IV (Medical Information Mart for Intensive Care IV) database. The association between admission base excess and mortality in postoperative patients with aortic dissection was assessed using multivariate Cox regression and Kaplan-Meier survival analysis. Subgroup analysis and receiver operating characteristic (ROC) curve analysis were employed to evaluate the predictive performance of base excess for in-hospital, 30-day, 90-day, and 1-year mortality.Results: A total of 196 patients were categorized into the normal base excess (-3 to +3 mmol/L) group and abnormal base excess (<-3 or >+3 mmol/L) group. Multivariate Cox regression analysis revealed that arterial base excess was a significant predictor of all-cause mortality across all periods. Subgroup analyses showed no significant interaction effects. The area under the ROC curve for base excess ranged from 0.640 to 0.745, indicating comparable predictive performance to existing scoring tools.Conclusion: Arterial base excess measured at admission is an effective and accessible predictor of mortality in patients with aortic dissection following surgical treatment.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 3","pages":"158-167"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11896762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A single center experience on clinical outcome of fundoplication in pediatric patients: a retrospective cohort study. 一项回顾性队列研究：单中心经验对儿科患者鼻窦炎临床结果的影响。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2025-03-01 Epub Date: 2025-02-28 DOI: 10.4174/astr.2025.108.3.177

Yuyoung Oh, Joong Kee Youn, Hee-Beom Yang, Hyun-Young Kim, Dayoung Ko

{"title":"A single center experience on clinical outcome of fundoplication in pediatric patients: a retrospective cohort study.","authors":"Yuyoung Oh, Joong Kee Youn, Hee-Beom Yang, Hyun-Young Kim, Dayoung Ko","doi":"10.4174/astr.2025.108.3.177","DOIUrl":"10.4174/astr.2025.108.3.177","url":null,"abstract":"Purpose: The study aimed to evaluate the characteristics and operative-related factors in children who underwent fundoplication, analyze surgical outcomes categorized by disease entity and surgical indication, and identify prognostic factors for reoperation risk.Methods: A total of 109 pediatric patients who underwent fundoplication between 2008 and 2022 were retrospectively analyzed. Patients were grouped by disease entity and surgical indication. Underlying diseases, comorbidities, sex, gestational age, birth weight, preoperative symptoms, and operation-related factors were examined. Outcomes were classified as short-term and long-term adverse events. We investigated differences in clinical outcomes according to disease entity and surgical indication. Then we statistically identified preoperative predictors for the risk of reoperation.Results: The most common disease entity was neurological impairment (n = 92). Pulmonary comorbidity (42.2%) and aspiration/regurgitation (87.2%) were the most common. Most surgeries were performed laparoscopically (86.2%). There were 12 short-term and 25 long-term adverse events, with long-term events occurred more frequently in the neurological impairment (NIP) group compared to the non-NIP group (P = 0.04). None of the factors showed a significant relationship with the risk of reoperation.Conclusion: Neurologically impaired children were more likely to experience long-term adverse events post-fundoplication. However, no significant predictors for reoperation risk were identified.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 3","pages":"177-185"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11896763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ulcerative colitis-associated colorectal neoplasm is increasing as a surgical indication in the biologics era: a retrospective observational study of 20 years of experience in a single tertiary center. 在生物制剂时代，溃疡性结肠炎相关的结直肠肿瘤作为手术指征正在增加：一项对单一三级中心20年经验的回顾性观察研究。

IF 1.2 4区医学

Annals of Surgical Treatment and Research Pub Date : 2025-03-01 Epub Date: 2025-02-28 DOI: 10.4174/astr.2025.108.3.150

Hyo Jun Kim, Seung-Bum Ryoo, Jin Sun Choi, Han-Ki Lim, Min Jung Kim, Ji Won Park, Seung-Yong Jeong, Kyu Joo Park

{"title":"Ulcerative colitis-associated colorectal neoplasm is increasing as a surgical indication in the biologics era: a retrospective observational study of 20 years of experience in a single tertiary center.","authors":"Hyo Jun Kim, Seung-Bum Ryoo, Jin Sun Choi, Han-Ki Lim, Min Jung Kim, Ji Won Park, Seung-Yong Jeong, Kyu Joo Park","doi":"10.4174/astr.2025.108.3.150","DOIUrl":"10.4174/astr.2025.108.3.150","url":null,"abstract":"Purpose: We aimed to identify changes in surgical indications in patients with ulcerative colitis (UC) in the biologics era in a single tertiary center.Methods: In this retrospective observational study, 108 patients with UC who underwent abdominal surgery for UC at Seoul National University Hospital from 2000 to 2021 were included. We compared the total number of patients undergoing UC before and after the introduction of biologic therapy.Results: Of the 108 patients with UC (male, 59 and female, 49; mean age, 46.8 years), 30 (27.8%) underwent surgery for neoplasms and 78 (72.2%) for medical intractability without neoplasms. The duration between diagnosis and surgery varied significantly (126.00 months vs. 60.50 months, P = 0.001). A significant difference was also noted in the surgical indications according to time (P = 0.02). Between 2000 and 2010, 12 patients (19.4%) underwent surgery for UC with neoplasms and 50 (80.6%) for UC without neoplasms, while between 2011 and 2021, 18 (39.1%) and 28 patients (60.9%) underwent surgery for UC with and without neoplasms, respectively.Conclusion: Since 2011, when biological agents were covered by insurance in South Korea, there has been a relative increase in the incidence of surgical indications for neoplasia cases. Focusing on closely monitoring individuals with long-term UC for neoplasms is necessary.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 3","pages":"150-157"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11896760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0