Antioxidants最新文献

{"title":"ELONGATED HYPOCOTYL5 Regulates Resistance to Root-Knot Nematode by Modulating Antioxidant System and Jasmonic Acid in <i>Cucumis sativus</i>.","authors":"Fusheng Ma, Juanqi Li, Mengwei Huang, Mengyan E, Dandan Cui, Guoxiu Wu, Shengli Li, Yang Li","doi":"10.3390/antiox14060679","DOIUrl":"10.3390/antiox14060679","url":null,"abstract":"<p><p>Root-knot nematodes (RKNs), specifically <i>Meloidogyne incognita</i>, are notoriously difficult to eliminate as endophytic nematodes, and cause severe damage to various plants. Cucumber (<i>Cucumis sativus</i>), which is a cash crop widely grown across the world, is often infected by RKNs. ELONGATED HYPOCOTYL5 (HY5), a member of the bZIP transcription factor family, plays a vital role in hormone, nutrient, abiotic stress, biotic stress, and oxygen species (ROS) signaling pathways. However, the involvement of HY5 in the defense against RKNs has rarely been reported. The present study initially explored the response of CsHY5 to RKNs. The results indicated that the <i>hy5</i> mutant had a higher number of nematodes and galls in the root system and exhibited a higher susceptibility to RKNs compared with the wild type (WT). Particularly, the root-knot nematodes in <i>hy5</i> plants completed their life cycle more quickly and produced more eggs. The activities of defense-related hormones and antioxidant enzymes were measured, and the results indicated that JA, jasmonoyl-isoleucine (JA-Ile), abscisic acid (ABA), peroxidase (POD), and ascorbate peroxidase (APX) were significantly elevated in the wild type, but were not induced or decreased in the mutant. Through transcriptome sequencing analysis and quantitative real-time PCR (qRT-PCR), it was found that when RKNs infect plants, the key genes of jasmonic acid (JA) synthesis, <i>CsAOC</i> and <i>CsAOS</i>, as well as the key gene of the antioxidant system, <i>CsPOD</i>, were all significantly induced. Nevertheless, this induction effect disappeared in the <i>hy5</i> mutant. Generally, CsHY5 plays a role in the response of cucumber to RKNs, and its deletion increases the sensitivity of cucumber to RKNs. These results suggest that <i>CsHY5</i> may affect the resistance of cucumber to RKNs by affecting antioxidant enzyme activities and hormone content.</p>","PeriodicalId":7984,"journal":{"name":"Antioxidants","volume":"14 6","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189740/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reactive Oxidative Species in Carotid Body Chemoreception: Their Role in Oxygen Sensing and Cardiorespiratory Alterations Induced by Chronic Intermittent Hypoxia.","authors":"Rodrigo Iturriaga, Hugo S Diaz","doi":"10.3390/antiox14060675","DOIUrl":"10.3390/antiox14060675","url":null,"abstract":"<p><p>The carotid body (CB) senses arterial PO₂, PCO₂, and pH levels, eliciting reflex responses to maintain cardiorespiratory homeostasis. Chronic intermittent hypoxia (CIH), the hallmark of obstructive sleep apnea, elicits autonomic and cardiorespiratory alterations that are attributed to an enhanced CB chemosensory responsiveness to hypoxia, which in turn activates neurons and glial cells in the nucleus of the tractus solitarius (NTS). Although the CB contribution to the CIH-induced pathological alterations is well-known, the underlying mechanisms are not fully understood. A growing body of new evidence suggests a crucial role for ROS in acute CB oxygen sensing, as well as in the potentiation of chemosensory discharge and the activation of the central chemoreflex pathway in CIH. Indeed, it has been proposed that acute hypoxia disrupts mitochondrial electron transport, increasing ROS and NADH in the chemoreceptor cells, which inhibit voltage-gated K⁺ channels, producing cell depolarization, Ca²⁺ entry, and release of excitatory transmitters. In addition, new evidence supports that the enhanced CB afferent discharge contributes to persistent CIH-induced cardiorespiratory alterations, likely triggering neuroinflammation in the NTS. Thus, in this review, we will examine the experimental evidence that supports the involvement of ROS in the acute O₂ sensing process, and their role in the enhanced CB chemosensory discharges, the glial-related inflammation in the NTS, and the cardiorespiratory alterations induced by CIH.</p>","PeriodicalId":7984,"journal":{"name":"Antioxidants","volume":"14 6","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Red Beetroot Skin Powder Addition as a Multifunctional Ingredient in Nougat.","authors":"Oana Emilia Constantin, Silvia Lazăr Mistrianu, Florina Stoica, Roxana Nicoleta Rațu, Doina Georgeta Andronoiu, Nicoleta Stănciuc, Marija Banožić, Nada Ćujić Nikolić, Zorana Mutavski, Gabriela Râpeanu","doi":"10.3390/antiox14060676","DOIUrl":"10.3390/antiox14060676","url":null,"abstract":"<p><p>Beetroot (<i>Beta vulgaris</i> L.) is a plant grown for its roots, which are used to obtain sugar, feed animals, and for human use. Beetroot skin, a by-product of food processing, is a significant source of bioactive compounds, including dietary fiber and antioxidants. The primary objective of this work was to utilize beetroot skin powder to produce value-added nougat. Analytical methods, like antioxidant activity tests, proximate analysis, and sensory assessments, are used to determine the impact of beetroot skin powder on the final product. The beetroot skin powder extract had a remarkable content of phytochemicals and antioxidant activity. The inhibitory effect of the extract was tested on enzymes linked to metabolic syndrome, oxidative stress, and inflammation. The beetroot skin powder extract inhibited α-glucosidase, α-amylase, lipase, and lipoxygenase enzymes. The characterization of value-added nougat illustrates the multifunctionality of beetroot peel powder within its composition, serving as a significant source of natural compounds with antioxidant, coloring, and flavoring properties. This enhances sensory attributes, including color, aroma, and texture, augmenting product diversity and consumer appeal. This is evidenced by the increase in the total content of betalains (3.77 ± 0.09 mg/g DW.) and polyphenols (69.48 ± 2.88 mg GAE/100 g DW.), which lead to high antioxidant activity (73.89 ± 3.65 mM Trolox/100 g DW.) for the nougat sample with 6% added beetroot powder. Thus, beetroot skin powder replaced chemically synthesized additives with antioxidants and natural pigments, improving life quality and implicitly capitalizing on beetroot processing by-products, supporting circular economy principles at the global level.</p>","PeriodicalId":7984,"journal":{"name":"Antioxidants","volume":"14 6","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189121/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carbon Dots-Enhanced Soy Protein Isolate/Polyvinyl Alcohol Composite Film for Active Preservation of Oxidation-Sensitive Foods.","authors":"Linlin Zhao, Huinan Jiang, Zhengxuan Han, Wenqin Gu, Bimal Chitrakar, Xiangren Meng","doi":"10.3390/antiox14060669","DOIUrl":"10.3390/antiox14060669","url":null,"abstract":"<p><p>Carbon dots perform a variety of functions when they are incorporated into active films synthesized from soy protein isolate/polyvinyl alcohol. The study examined the impact of varying concentrations of carbon dots on the structural, bioactive, and physicochemical properties of composite films. The addition of carbon dots improved the UV-blocking rate (up to 99.64%) with a higher water-barrier property of the films. The films with carbon dot-enhanced antioxidant activities (ABTS was 99.71%, and DPPH was 51.44%) exhibited strong antibacterial activities against <i>Escherichia coli</i> and <i>Staphylococcus aureus</i>. In a hydrophilic environment, the high release rate of carbon dots was found to enhance the biological activity of films. The application of 0.8% composite film resulted in significant shelf-life extension for fresh jujubes, meatballs, and soybean oil. These results demonstrated the feasibility of composite films as an active packaging material.</p>","PeriodicalId":7984,"journal":{"name":"Antioxidants","volume":"14 6","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biosynthetic Machinery to Abiotic Stress-Driven Emission: Decoding Multilayer Regulation of Volatile Terpenoids in Plants.","authors":"Yingying Shan, Songheng Jin","doi":"10.3390/antiox14060673","DOIUrl":"10.3390/antiox14060673","url":null,"abstract":"<p><p>Volatile terpenoids (VTs) are key secondary metabolites that play dual roles as endogenous antioxidants and airborne signals in plants under abiotic stress. Their biosynthesis is orchestrated via the mevalonate (MVA) and 2-C-methyl-D-erythritol 4-phosphate (MEP) pathways, with metabolic plasticity regulated by transcription factors, phytohormonal crosstalk, and stress-responsive elements. Recent advances have revealed that VTs such as isoprene, monoterpenes, and sesquiterpenes help mitigate oxidative stress by scavenging reactive oxygen species (ROS) and modulating antioxidant enzyme systems. However, regulatory mechanisms of stress-induced VT emissions remain fragmented and species-dependent. This review synthesizes current knowledge of VT biosynthesis and emission under abiotic stress, highlights their antioxidant functions and regulatory architecture, and underscores their protective roles in redox homeostasis and stress signal transduction. By identifying key metabolic nodes (e.g., TPS, DXS and MYC2) and stress-responsive pathways, we propose potential molecular targets for the development of stress-resilient cultivars. The integration of VT-based traits into breeding strategies and production-oriented metabolic engineering offers promising avenues for improving crop performance, reducing oxidative damage, and supporting sustainable agricultural systems.</p>","PeriodicalId":7984,"journal":{"name":"Antioxidants","volume":"14 6","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12190140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing Antioxidants in Cancer Therapy: Opportunities, Challenges, and Future Directions.","authors":"Yu'e Liu, Guangzhen Wu, Linjing Feng, Jialing Li, Yuyang Xia, Wenjia Guo, Kaijun Zhao","doi":"10.3390/antiox14060674","DOIUrl":"10.3390/antiox14060674","url":null,"abstract":"<p><p>Antioxidants neutralize reactive oxygen species and free radicals, protecting cells from oxidative damage and maintaining cellular homeostasis. In cancer therapy, they play a complex dual role, serving as protective agents against oxidative stress while, under certain conditions, acting as pro-oxidants that may promote tumorigenesis and resistance to treatment. Redox regulation is governed by key antioxidant pathways, such as the BACH1 and NRF2 pathways, along with transcriptional factors that significantly affect cancer progression and immunotherapy response. In addition to their intracellular effects, antioxidants modulate the tumor microenvironment, including interactions with the extracellular matrix, which impact cancer cell behavior and therapeutic responses. This review also explores preclinical studies that investigate the roles of major antioxidants in cancer biology. While these studies present promising data, significant challenges persist, including the potential for antioxidants to interfere with standard cancer treatments or to inadvertently support tumor survival. We further highlight emerging strategies aimed at optimizing antioxidant therapy, including personalized medicine approaches, nanoparticle-based delivery systems, and combination treatments with immunotherapies and targeted therapies. By examining the therapeutic potential and associated risks of antioxidants, this review provides critical insights into their role in cancer treatment and offers a roadmap for advancing antioxidant-based strategies to improve clinical outcomes.</p>","PeriodicalId":7984,"journal":{"name":"Antioxidants","volume":"14 6","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantification of Phenolic Compounds in Olive Oils by Near-Infrared Spectroscopy and Multiple Regression: Effects of Cultivar, Hydroxytyrosol Supplementation, and Deep-Frying.","authors":"Taha Mehany, José M González-Sáiz, Consuelo Pizarro","doi":"10.3390/antiox14060672","DOIUrl":"10.3390/antiox14060672","url":null,"abstract":"&lt;p&gt;&lt;p&gt;Near-infrared (NIR) spectroscopy, combined with multivariate calibration techniques such as stepwise decorrelation of variables (SELECT) and ordinary least squares (OLS) regression, was used to develop robust, reduced-spectrum regression models for quantifying key phenolic compound markers in various olive oils. These oils included nine extra virgin olive oil (EVOO) varieties, refined olive oil (ROO) blended with virgin olive oil (VOO) or EVOO, and pomace olive oil, both with and without hydroxytyrosol (HTyr) supplementation. Olive oils were analyzed before and after deep frying. The results show that HTyr ranged from 7.28 mg/kg in Manzanilla (lowest) to 21.43 mg/kg in Royuela (highest). Tyrosol (Tyr) varied from 5.87 mg/kg in Royuela (lowest) to 14.86 mg/kg in Hojiblanca (highest). Similar trends were observed in all phenolic fractions across olive oil cultivars before and after deep-frying. HTyr supplementation significantly increased both HTyr and Tyr levels in non-fried and fried supplemented oils, with HTyr rising from single digits in some controls (around 0 mg/kg) to over 300 mg/kg in most of the supplemented samples. SELECT efficiently reduced redundancy by selecting the most vital wavelengths and thus significantly improved the regression models for key phenolic compounds, including HTyr, Tyr, caffeic acid, decarboxymethyl ligstroside aglycone in dialdehyde form (oleocanthal), decarboxymethyl oleuropein aglycone in dialdehyde form (oleacein), homovanillic acid, pinoresinol, oleuropein aglycone in oxidized aldehyde and hydroxylic form (OAOAH), ligstroside aglycone in oxidized aldehyde and hydroxylic form (LAOAH), and total phenolic content (TPC), achieving correlation coefficients (R) of 0.91-0.98. The SELECT-OLS method generated highly predictive models with minimal complexity, using at most 30 wavelengths out of 700. The number of decorrelated predictors varied, at 12, 14, 15, 30, 30, 21, 30, 30, 30, and 18 for HTyr, Tyr, caffeic acid, oleocanthal, oleacein, homovanillic acid, pinoresinol, OAOAH, LAOAH, and TPC, respectively, demonstrating the adaptability of the SELECT-OLS approach to different spectral patterns. These reliable calibration models enabled online and routine quantification of phenolic compounds in EVOO, VOO, ROO, including both non-fried and fried as well as supplemented and non-supplemented samples. They performed well across eight deep-frying conditions (3-6 h at 170-210 °C). Implementing an NIR instrument with optimized variable selection would simplify spectral analysis and reduce costs. The developed models all demonstrated strong predictive performance, with low leave-one-out mean prediction errors (LOOMPEs) with values of 15.69, 8.47, 3.64, 9.18, 16.71, 3.26, 8.57, 13.56, 56.36, and 82.38 mg/kg for HTyr, Tyr, caffeic acid, oleocanthal, oleacein, homovanillic acid, pinoresinol, OAOAH, LAOAH, and TPC, respectively. These results confirm that NIR spectroscopy combined with SELECT-OLS is a feasible, rapid, non-d","PeriodicalId":7984,"journal":{"name":"Antioxidants","volume":"14 6","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploratory Evaluation of Circulating Microbiota-Derived Corisin Levels in Women with Adverse Pregnancy Outcomes.","authors":"Maya Kato, Masafumi Nii, Kuniaki Toriyabe, Yuya Tamaishi, Sho Takakura, Shoichi Magawa, Taro Yasuma, Corina N D'Alessandro-Gabazza, Hajime Fujimoto, Masaaki Toda, Isaac Cann, Tetsu Kobayashi, Esteban C Gabazza, Eiji Kondo, Tomoaki Ikeda","doi":"10.3390/antiox14060670","DOIUrl":"10.3390/antiox14060670","url":null,"abstract":"<p><p>Preterm birth and low birth weight remain major contributors to neonatal morbidity and mortality, yet the underlying mechanisms are not fully understood. Maternal microbiota has been implicated in adverse pregnancy outcomes, but key mediators remain unidentified. We previously showed that the microbiota-derived peptide corisin induces epithelial apoptosis via mitochondrial membrane depolarization and reactive oxygen species accumulation. In this retrospective preliminary study, we evaluated the association between maternal serum corisin levels and pregnancy outcomes in 84 eligible women. Among them, 10 experienced preterm birth, and 22 delivered low-birth-weight infants. Corisin levels were significantly elevated in these groups compared with women with full-term, normal-weight deliveries. Preterm birth was associated with increased tissue factor, while low birth weight correlated with higher thrombin-antithrombin complex and soluble thrombomodulin and lower fibrinogen levels. Corisin concentrations showed negative correlations with maternal BMI, birth weight and length, and estimated fetal weight. Positive correlations were observed between corisin, myeloperoxidase, and several coagulation markers. These preliminary findings suggest that elevated maternal corisin levels are associated with adverse pregnancy outcomes and may reflect underlying mechanisms involving oxidative stress and coagulation activation. Further investigation is warranted to clarify its potential role as a microbiota-derived biomarker in pregnancy complications.</p>","PeriodicalId":7984,"journal":{"name":"Antioxidants","volume":"14 6","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrafast ROS Scavenging Activity of Amur Maple Tree Extracts Confers Robust Cardioprotection for Myocardial Ischemia/Reperfusion Injury.","authors":"Aoyang Pu, Woo-Sup Sim, Yuen-Kei Liem, Yimin Lai, Bong-Woo Park, Kyoung-Tae Lee, Hun-Jun Park, Kiwon Ban","doi":"10.3390/antiox14060671","DOIUrl":"10.3390/antiox14060671","url":null,"abstract":"<p><p><i>Ginnalin A</i> (GA), a polyphenolic compound derived from amur maple trees, has been identified as a powerful scavenger of reactive oxygen species (ROS). Recognizing the pivotal role of ROS in exacerbating secondary damage during myocardial ischemia-reperfusion injury (MIRI), we fractionated GA-enriched extracts from the leaves of the amur maple tree, <i>Acer tataricum</i> L. subsp. <i>ginnala</i> (<i>Maxim.</i>) <i>Wesm.</i>, using common solvents of dichloromethane (DCM) and ethyl acetate (EA). When co-administered for 30 min, the DCM- and EA-fractioned extracts effectively protected cardiomyocytes from H₂O₂-induced damage. ROS-sensitive probes indicated that treatment with <i>ginnala</i> extracts significantly reduced both intracellular and mitochondrial ROS levels. Instead of enhancing the activity of antioxidative enzymes, the <i>ginnala</i> extracts acted as natural antioxidases, directly scavenging various ROS such as superoxide, H₂O₂, hydroxyl radical, and Fe²⁺ within just 20 min. In a MIRI rat model, the in vivo administration of <i>ginnala</i> extracts provided significant cardioprotection by preserving viable myocardia and enhancing cardiac functions. Additionally, treatment with <i>ginnala</i> extracts significantly reduced cardiac fibrosis and denatured collagen. Our study suggests that the ultrafast ROS scavenging capability of <i>ginnala</i> extracts offers substantial heart protection during MIRI. Incorporating <i>ginnala</i> extracts as a pharmacological intervention during reperfusion could effectively mitigate ROS-induced cardiac injury.</p>","PeriodicalId":7984,"journal":{"name":"Antioxidants","volume":"14 6","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Zhao et al. Protective Effects of 17-βE₂ on the Primary Hepatocytes of Rainbow Trout (<i>Oncorhynchus mykiss</i>) Under Acute Heat Stress. <i>Antioxidants</i> 2024, <i>13</i>, 1316.","authors":"Guiyan Zhao, Zhe Liu, Junhao Lu, Jinqiang Quan, Yucai Pan","doi":"10.3390/antiox14060659","DOIUrl":"10.3390/antiox14060659","url":null,"abstract":"<p><p>In the original publication [...].</p>","PeriodicalId":7984,"journal":{"name":"Antioxidants","volume":"14 6","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12169199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}