Antimicrobial Resistance and Infection Control最新文献

{"title":"Preventing outbreaks in burn units: the role of hygiene compliance and early warning systems.","authors":"Marie Lindblad, Fredrik Huss, Eva Tano, Birgitta Lytsy, Susanne Sütterlin","doi":"10.1186/s13756-025-01592-9","DOIUrl":"10.1186/s13756-025-01592-9","url":null,"abstract":"<p><strong>Background and objectives: </strong>To analyse observations of staff's hand hygiene, usage of gloves and plastic aprons, and dress code compliance at the Burn Centre, Uppsala University Hospital in Sweden, and to evaluate the association between hygiene non-compliance and outbreak periods. Furthermore, to explore the potential of using routine hygiene observations as an early warning tool for the risk of uncontrolled spread of (multidrug-resistant) bacteria.</p><p><strong>Methods: </strong>Direct observations of the personnel's compliance with hand hygiene, usage of gloves and plastic aprons, and dress code were studied in relation to two A. baumannii outbreaks in 2014 and 2020. Interrupted time series analyses were conducted from 2013 to 2017 and 2018 to 2022 to evaluate outbreak intervention measures. Rolling sums of observed hygiene errors and 90th percentiles were calculated for four-, five-, and six-month periods.</p><p><strong>Results: </strong>During the study, 13,216 direct observations showed hygiene compliance ranging from 70 to 100% per category. Infection control interventions significantly reduced non-compliance after both outbreaks, with sustained improvements for two years following the first outbreak. Rolling four- to six-month sums, using 90th percentile thresholds of seven, nine, and eleven non-compliances predicted A. baumannii outbreaks.</p><p><strong>Conclusion: </strong>In this setting, compliance levels above 97% were consistently observed during outbreak-free periods, suggesting a potential protective effect. Focus on non-compliance as a key metric and rolling sums of non-compliance, may support early detection of increased outbreak risk and guide preventive interventions.</p>","PeriodicalId":7950,"journal":{"name":"Antimicrobial Resistance and Infection Control","volume":"14 1","pages":"75"},"PeriodicalIF":4.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12210931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144537817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the COVID-19 pandemic on surgical site infections: a multi-center study evaluating incidence, pathogen distribution, and antimicrobial resistance patterns.","authors":"Şiran Keske, Elif Sargın Altunok, Emel Azak, Ezgi Gülten, Tuğba Arslan Gülen, Çiğdem Ataman Hatipoğlu, Ali Asan, Derya Korkmaz, Bahar Kaçmaz, Yeşim Kızmaz, Ayşe Batırel, Fethiye Akgül, Derya Yapar, Zehra Çağla Karakoç, Ayşe Serra Özel, Tuğba Yanık Yalçın, Deniz Özer, Özge Eren Korkmaz, Ahmet Şahin, Muhammed Fatih Karaşın, Tuba Turunç, Mehtap Aydın, Neşe Demirtürk, Alpay Azap, Önder Ergönül","doi":"10.1186/s13756-025-01542-5","DOIUrl":"10.1186/s13756-025-01542-5","url":null,"abstract":"<p><strong>Background: </strong>Surgical site infections (SSIs) are among the most significant concerns in healthcare settings, presenting challenges in patient management and healthcare outcomes. The emergence of the COVID-19 pandemic has further complicated the landscape of infectious disease epidemiology, impacting the distribution and resistance characteristics of pathogens responsible for SSIs. Understanding these dynamics is essential for improving infection prevention and treatment strategies.</p><p><strong>Methods: </strong>This retrospective multi-center study included 17 hospitals in Turkey, analyzing SSI cases from January 2019 to January 2023. The study was divided into three phases: pre-pandemic (January 2019 - March 2020), early pandemic (March 2020 - January 2022), and late pandemic (January 2022 - January 2023). We assessed demographic and clinical characteristics, pathogen distributions, and resistance rates, focusing on multidrug-resistant (MDR) pathogens.</p><p><strong>Results: </strong>A total of 2,058 patients with SSIs were included. The SSI rate increased from 0.79% in 2019 to 0.87% in 2020, then decreased to 0.46% in 2021 and 0.50% in 2022. The most prevalent pathogens were E. coli (21.9%) and K. pneumoniae (14.6%). Resistance to meropenem in K. pneumoniae rose from 23% pre-pandemic to 33% post-pandemic, while ceftazidime-avibactam resistance surged from 6 to 43%. P. aeruginosa showed increased quinolone resistance from 18 to 27%, with colistin resistance rising to 13% in the late pandemic phase.</p><p><strong>Conclusions: </strong>This study highlights the significant impact of the COVID-19 pandemic on SSIs in Turkey, revealing concerning trends in antibiotic resistance among key pathogens. Ongoing surveillance and enhanced infection control measures are essential to address these challenges and improve patient outcomes in the post-pandemic era.</p>","PeriodicalId":7950,"journal":{"name":"Antimicrobial Resistance and Infection Control","volume":"14 1","pages":"77"},"PeriodicalIF":4.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12217381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144537813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of knowledge, attitudes, and practices related to antibiotics and antimicrobial resistance awareness among community members in Ghana and Burkina Faso.","authors":"Elisenda Cama I Gibernau, Leslie Mawuli Aglanu, Alphonse Zakane, Denise Dekker, Albrecht Jahn, Ali Sié, John Humphrey Amuasi, Aurélia Souares","doi":"10.1186/s13756-025-01594-7","DOIUrl":"10.1186/s13756-025-01594-7","url":null,"abstract":"<p><strong>Background: </strong>Antimicrobial resistance (AMR) is a global health concern, particularly in low- and middle-income countries. As human behaviour plays a crucial role in the emergence and spread of resistance, data on the understanding of AMR awareness are very important for assessing the situation and developing effective interventions. The aim of this study was to analyse the knowledge, attitudes and practices (KAP) related to antibiotics and awareness towards antibiotic resistance among community members in two districts in Ghana, and Burkina Faso.</p><p><strong>Methods: </strong>A cross-sectional survey was used to collect data on socio-demographic, economic factors, and KAP. In Burkina Faso a simple randomization was carried out, whereas in Ghana we performed a double-stage randomization. The data was collected using an electronic data capture between February and March 2023 in Ghana, and from July to November 2023 in Burkina Faso. Data analysis employed descriptive statistics, and logistic regressions.</p><p><strong>Results: </strong>A total of 1,114 participants in Ghana and 1,011 in Burkina Faso were included. The majority knew the term \"Antibiotic\" (Ghana: n = 687, 61.67%; Burkina Faso: n = 767, 75.87%), but only a minority were aware of AMR (Ghana: n = 381, 34.2%; Burkina Faso: n = 270, 26.71%). In both countries, participants had a middle level of knowledge about antibiotics (Ghana: n = 597; 53.59%, Burkina Faso: n = 502, 49.65%), positive attitudes towards antibiotic utilization (Ghana: n = 702, 63.02%; Burkina Faso: n = 510, 50.45%), and most of them reported a responsible use of antibiotics (Ghana: n = 875, 78.55%; Burkina Faso: n = 713, 70.52%).</p><p><strong>Conclusions: </strong>Despite familiarity with antibiotics, self-reported responsible use did not align with actual observed behaviours in both countries. Additionally, a significant lack of awareness about AMR highlights the need for a targeted educational intervention to enhance understanding of its risks and increase appropriate practices.</p>","PeriodicalId":7950,"journal":{"name":"Antimicrobial Resistance and Infection Control","volume":"14 1","pages":"72"},"PeriodicalIF":4.8,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12199504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reasons for insufficient compliance with infection prevention and control measures in the intensive care unit: a qualitative study conducted in Türkiye in 2024.","authors":"Bahar Madran, Zeynep Ilgin Demir, Busra Yalcin, Oguz Taha Ayaz, Kaan Iyikosker, Aleyna Keskin, Azra Gorel, Yunus Aksoy, Nilayda Sagaltici, Koray Hacioglu, Ilker Kayi, Önder Ergönül, Sibel Sakarya, Şiran Keske","doi":"10.1186/s13756-025-01544-3","DOIUrl":"10.1186/s13756-025-01544-3","url":null,"abstract":"<p><strong>Background: </strong>In EU countries, 33,000 people die of antibiotic-resistant infections annually, and Türkiye is one of the countries with the highest rate of antimicrobial resistance. More than 70% of these infections are directly related to healthcare-associated infections (HAIs). Implementing IPC measures is critical to preventing HAIs in ICUs, with the highest risk of HAIs. However, compliance with IPC measures by HCWs is suboptimal. In this study, we aimed to identify the barriers to compliance with infection prevention and control (IPC) measures in intensive care units (ICUs) and to find solutions by interviewing healthcare workers (HCWs).</p><p><strong>Methods: </strong>The study used a qualitative approach with in-depth face-to-face interviews. Between March 1 and May 31, 2024, 20 HCWs were interviewed in five tertiary hospitals in Istanbul. Purposive sampling included at least three HCWs from each hospital: an IPC nurse or physician, an ICU physician, and an ICU nurse. The conceptual framework of the semi-structured interview guide was based on the Health Belief Model (HBM).</p><p><strong>Results: </strong>The majority of HCWs were aware of the importance and benefits of IPC measures; however, none reported full compliance. A significant proportion of HCWs (n = 16) reported that in-service training programs conducted by infection control committees were not effective enough to positively influence staff behaviuor. Increased workload (n = 13) and unexpected medical emergencies interrupting IPC activities (n = 13) were also cited as barriers to compliance. More than half of respondents indicated that increased sanctions (n = 11), stricter control mechanisms (n = 11), and more effective IPC training programs (n = 11) would help improve compliance rates.</p><p><strong>Conclusions: </strong>Addressing barriers and implementing tailored solutions can significantly enhance compliance. By integrating innovative training programs, improving working conditions, and strengthening enforcement mechanisms, hospital administrators and IPC committees can foster a safer environment for patients, HCWs, and the broader community.</p>","PeriodicalId":7950,"journal":{"name":"Antimicrobial Resistance and Infection Control","volume":"14 1","pages":"71"},"PeriodicalIF":4.8,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12186410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of catheter dwell time on the risk of central line-associated bloodstream infections in central venous catheters and peripherally inserted central catheters.","authors":"Vassiliki Pitiriga, Elsa Campos, John Bakalis, Konstantinos Sagris, George Georgiadis, George Saroglou, Athanasios Tsakris","doi":"10.1186/s13756-025-01590-x","DOIUrl":"10.1186/s13756-025-01590-x","url":null,"abstract":"<p><strong>Background: </strong>Understanding the impact of catheter dwell time on the risk of central-line associated bloodstream infections (CLABSIs) is crucial to developing effective infection prevention strategies. The aim of the study was to evaluate the relationship between catheter dwell time and the risk of CLABSIs caused by multidrug-resistant and common pathogens in patients with central venous catheters (CVCs) and peripherally inserted central catheters (PICCs).</p><p><strong>Methods: </strong>We retrospectively analysed data from patients admitted consecutively to a tertiary care Greek hospital from 2018-2020. Events were categorized into three groups based on 10-days' intervals: group 1 (≤ 10 days), group 2 (11-20 days), and group 3 (> 21 days).</p><p><strong>Results: </strong>Α total of 84 patients (mean age 56.4 ± 19.6 years) were included in the study. Among them, 62 (73.8%) had CVC, while 22 (26.2%) had PICC placement. In the CVC cohort, a statistically significant difference in CLABSI rates was observed, with rates of 4.49, 5.57, and 8.54 per 1,000 catheter/days for groups 1, 2, and 3 respectively (p < 0.001). Similarly, higher rates of MDROs were found in group 3, with rates of 2.93, 3.71, and 4.47 per 1,000 catheter/days for groups 1, 2, and 3, respectively (p = 0.01). Regarding the PICC cohort, significant differences in CLABSI rates were observed among the three groups, with rates of 0.93, 2.25, and 1.67 per 1,000 catheter/days for groups 1, 2, and 3, respectively (p < 0.001).</p><p><strong>Conclusion: </strong>Our results emphasize the critical role of catheter selection and duration management in mitigating CLABSI risk, especially for patients with CVCs.</p>","PeriodicalId":7950,"journal":{"name":"Antimicrobial Resistance and Infection Control","volume":"14 1","pages":"70"},"PeriodicalIF":4.8,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reprocessing status of flexible bronchoscopes in 202 intensive care units in Hubei province, China: a multicentre cross-sectional study.","authors":"Yaqi Yu, Weijun Peng, Li Tan, Qi Xiao, Yixuan Wang, Chunling Guo, Juan Deng, Mengyao Jiang","doi":"10.1186/s13756-025-01593-8","DOIUrl":"10.1186/s13756-025-01593-8","url":null,"abstract":"<p><strong>Background: </strong>Unstandardised reprocessing procedures for flexible endoscopes can lead to infection outbreaks and threaten the lives of ICU patients. Despite recent updates to technical specification, there was a paucity of studies on the current status of flexible endoscopic reprocessing, particularly concerning flexible bronchoscopes (FB). This study aimed to assess the current practices of reprocessing FBs in ICUs in Hubei Province, China.</p><p><strong>Methods: </strong>A cross-sectional study was conducted utilizing convenience sampling from October 11, 2024, to December 6, 2024, in the ICUs of 216 hospitals in Hubei Province, China. A self-developed questionnaire was distributed through an online survey platform to either the person in charge of the ICU or the frontline technicians. The information regarding the reprocessing of FBs was collected, including general characteristics, personnel and training, layout and facilities, reprocessing operations, and reprocessing quality monitoring.</p><p><strong>Results: </strong>The content validity index of the questionnaire was 0.94. There were 202 valid questionnaires collected with a validity rate of 93.52%, including 158 ICUs in tertiary hospitals and 44 in secondary and primary hospitals. The ICUs of tertiary hospitals were better than the ICUs of secondary and primary hospitals in terms of the number of FBs available, the number of dedicated technicians, the opportunity for training, the availability of some equipment and facilities (ultrasonic cleaners, whole tube irrigators, etc.), and some reprocessing operations (FB sterilisation method and storage cabinet sterilisation frequency) (P < 0.05).</p><p><strong>Conclusions: </strong>There were variations in FB reprocessing practices across ICUs in hospitals of all levels in Hubei, along with some common issues. Most ICUs were standardised in personnel training, operation, and recording, and ICUs in tertiary hospitals behaved better than in secondary and primary hospitals. However, there remained a need for improvement in the layout of the reprocessing environment, equipment configuration, and quality monitoring. Future research could apply implementation science to identify barriers and propose strategies to align practice with guidelines.</p>","PeriodicalId":7950,"journal":{"name":"Antimicrobial Resistance and Infection Control","volume":"14 1","pages":"69"},"PeriodicalIF":4.8,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12175463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of five versus two personnel on bacterial air contamination during preparation of sterile surgical goods in the operating room: a randomised controlled trial.","authors":"Camilla Wistrand, Bo Söderquist, Ann-Sofie Sundqvist","doi":"10.1186/s13756-025-01589-4","DOIUrl":"10.1186/s13756-025-01589-4","url":null,"abstract":"<p><strong>Background: </strong>Surgical site infection (SSI) and antimicrobial resistance are a worldwide problem affecting patient safety. It is lacking randomised controlled trials (RCT) regarding how the number of personnel in the operating room (OR) affects the air quality. We aimed to investigate the effect the number of personnel in the OR have on bacterial air contamination during the preparation of sterile surgical goods, to identify the species and antibiotic susceptibility of the bacteria isolated, and to describe the number of SSIs together with causative microorganisms.</p><p><strong>Methods: </strong>This RCT used an intervention group in which two individuals prepared the surgical goods and a control group in which five individuals prepared the goods. Bacteria were isolated on aerobic and anaerobic plates, and bacterial growth was measured as colony forming units (CFU). All isolates were typed, and types known to cause SSI were tested for susceptibility to eight antibiotics. Data were analysed with the Mann-Whitney U test, the chi-square test, or Fisher's exact test.</p><p><strong>Results: </strong>Results were based on 69 open-heart surgeries and 414 plates. When sterile surgical goods were prepared with two personnel, the median CFU was 2 with an IQR of 2, compared with five personnel, the median CFU was 5, with an IQR of 5 (p < 0.001). The 272 CFU represented 45 different bacterial species, with 38 species isolated in the control group and 21 in the intervention group. The most frequently isolated bacteria were Cutibacterium acnes (82/272, 30%), and Staphylococcus epidermidis (36/272, 13%). Of the 36 S. epidermidis isolates, 11 (31%) were drug-resistant, including three multidrug-resistant. One patient in the control group was infected by Staphyloccocus aureus and Staphylococcus lugdunensis, neither of which was isolated during the preparation of sterile goods. One patient in the intervention group developed an SSI caused by C. acnes, Corynebacterium kroppenstedtii, and S. epidermidis. C. acnes and S. epidermidis were isolated during the preparation.</p><p><strong>Conclusions: </strong>Minimising the number of personnel in the OR during preparation of sterile surgical goods is important to reduce the bacterial load.</p><p><strong>Trial registration: </strong>Prospectively 15 May 2022 at FoU Sweden (275659) and retrospectively 22 October 2022 at ClinicalTrials.Gov (NCT05597072).</p>","PeriodicalId":7950,"journal":{"name":"Antimicrobial Resistance and Infection Control","volume":"14 1","pages":"68"},"PeriodicalIF":4.8,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12168327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of educational interventions provided to patients with a central venous catheter and their informal caregivers: a systematic review.","authors":"L Foucault-Fruchard, N van der Mee, C Reinprecht, C Durand, J Cailhol, J R Zahar, S Kerneis","doi":"10.1186/s13756-025-01583-w","DOIUrl":"10.1186/s13756-025-01583-w","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Central venous catheters offer considerable benefits, but their presence can expose patients to serious complications. Preventing such complications is crucial, not only for individual patients, but also for hospitals and the healthcare system.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To assess the impact of educational interventions on clinical and non-clinical outcomes provided to patients with central venous catheters and/or their informal caregivers, regardless of the therapeutic indication, and to define the specific characteristics of effective educational strategies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Medline and Embase were searched, covering all publications since their inception to 13 August 2024. Articles on clinical and/or non-clinical outcomes related to the education of patients with central venous catheters and their informal caregivers were included. Studies focusing solely on the education of healthcare providers were excluded. The reference lists of included studies were hand searched for additional citations. This systematic review followed PRISMA guidelines and the protocol was registered in PROSPERO (CRD42024577193). The quality of the included studies was assessed using the Mixed Methods Appraisal Tool.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;In total, 20 articles, representing 974 patients and 875 informal caregivers, were included in the review: seven randomized trials, ten quantitative studies without randomization, and three descriptive quantitative studies. The compliance rate of 60% for the randomised trials determined using the Mixed Methods Appraisal Tool indicates a low risk of bias, whereas non-randomised and descriptive quantitative studies show more methodological weaknesses (40% and 45%, respectively). There was a positive trend, significant or not, for the impact of patient education on reducing complications, particularly those related to infection (85% of the studies concerned by this outcome). This was often observed (64%) in studies based on educational interventions repeated over time. Studies that showed a significant improvement in patients' knowledge and skills in terms of self-management showed beneficial results in terms of the occurrence of complications. Nurses were the most common educators (15/20), and the most frequently used tools were written materials and digital resources, often combined with other methods for greater effectiveness.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;This systematic review encourages the implementation of educational interventions for patients with central venous catheters and their informal caregivers, notably to decrease infections. Providing them with written documents and digital tools, and delivering them repeatedly over time, should be promoted. However, study heterogeneity limits definitive conclusions. Future research should standardize methodologies, involve patients in intervention design, and assess cost-effectiveness to ensure sustainable implementa","PeriodicalId":7950,"journal":{"name":"Antimicrobial Resistance and Infection Control","volume":"14 1","pages":"67"},"PeriodicalIF":4.8,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuous versus intermittent cuff pressure monitoring in preventing ventilator-associated pneumonia: a multicentre randomised controlled trial.","authors":"Yanshuo Wu, Yunhao Su, Liping Zhao, Xi Wang, Kun Zhang, Yuhong Chen, Xiaokun Zhang, Peng Gao, Kangkang Shen, Chencong Li, Yanling Yin, Congcong Zhao","doi":"10.1186/s13756-025-01579-6","DOIUrl":"10.1186/s13756-025-01579-6","url":null,"abstract":"","PeriodicalId":7950,"journal":{"name":"Antimicrobial Resistance and Infection Control","volume":"14 1","pages":"66"},"PeriodicalIF":4.8,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12150450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing infection control training in ICUs using the Kirkpatrick model: a prospective cohort study.","authors":"Sahar Elsheikh, Afaf Magdy, Lamiaa Asem","doi":"10.1186/s13756-025-01587-6","DOIUrl":"10.1186/s13756-025-01587-6","url":null,"abstract":"<p><strong>Background: </strong>Hospital-acquired infections (HAIs) are a significant global health challenge, particularly in intensive care units (ICUs), where patient vulnerability is high. Effective infection prevention and control (IPC) training is critical for reducing HAIs and improving healthcare outcomes. This aims to evaluate the efficacy of an IPC training program via Kirkpatrick's four-level model.</p><p><strong>Methods: </strong>A prospective cohort study was conducted between June and December 2024 at Shebin El Kom Fever Hospital's ICU. The study involved 106 healthcare workers (84 nurses, 22 physicians) who participated in a two-month training program combining theoretical lectures and practical sessions. Program effectiveness was assessed via Kirkpatrick's 4 levels: reaction (satisfaction surveys), learning (knowledge tests), behavior (direct observation), and results (clinical outcomes).</p><p><strong>Results: </strong>Ninety health care workers (HCWs) whose level of satisfaction exceeded 80% across all training aspects (Level 1) were included. The knowledge assessment revealed a significant improvement in the mean test score from 76.93 to 82.29% (p = 0.0112) (Level 2). Behavioral evaluation revealed substantial improvements in infection control practices, particularly in nurses' aseptic procedures (40.00-83.54%, p < 0.001) and physicians' personal protective equipment (PPE) usage (19.05-62.50%, p = 0.0391) (Level 3). At Level 4, no significant changes were observed in HAIs, mortality rates, or hospital stay costs.</p><p><strong>Conclusion: </strong>IPC training programs significantly enhance HCW knowledge and compliance with infection control practices, laying the groundwork for sustainable ICU infection control. While immediate improvements in hospital metrics were not observed, long-term monitoring is crucial to achieving full benefits. Enhanced compliance may reduce HAIs and associated costs over time.</p>","PeriodicalId":7950,"journal":{"name":"Antimicrobial Resistance and Infection Control","volume":"14 1","pages":"65"},"PeriodicalIF":4.8,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12150569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}