Paula Hinkl, Elmar Graessel, Nicolas Rohleder, Peter Landendoerfer, Thomas Kuehlein, Natascha Lauer, Anna Pendergrass
{"title":"Validation of the Mild Behavioral Impairment Scale (MBI-S) for brief self-assessment of Mild Behavioral Impairment in people without dementia.","authors":"Paula Hinkl, Elmar Graessel, Nicolas Rohleder, Peter Landendoerfer, Thomas Kuehlein, Natascha Lauer, Anna Pendergrass","doi":"10.1186/s12991-025-00566-w","DOIUrl":"10.1186/s12991-025-00566-w","url":null,"abstract":"<p><strong>Background: </strong>Mild Cognitive Impairment (MCI) and Mild Behavioral Impairment (MBI) are important constructs in the context of cognitive decline. MBI can be assessed with the Mild Behavioral Impairment Checklist (MBI-C). However, the instrument has deficits in psychometrics and content, thus indicating a need for improvement. The aim of this study was to develop a complementary short instrument, the Mild Behavioral Impairment Scale (MBI-S), designed to measure MBI as a short-term modifiable state criterion, and to validate it in a non-clinical sample of people 18 years of age or older.</p><p><strong>Methods: </strong>Most of the items on the MBI-S stem from the MBI-C and were chosen to represent the dimensions of the Neuropsychiatric Inventory Questionnaire. The MBI-S was validated on self-reported data from 175 individuals. In an item analysis, the discriminatory power and item difficulties were examined. Cronbach's alpha was calculated to assess the internal consistency, and a principal component analysis was conducted to determine the structure of the instrument. Construct validity was established by testing four hypotheses about relationships between the MBI-S and other instruments by calculating correlation coefficients.</p><p><strong>Results: </strong>After the item analysis, two items were removed from the final version of the scale on the basis of insufficient discriminatory power and the finding that the internal consistency of the total score increased when the items were deleted. The principal component analysis yielded a single-component structure for the MBI-S. Two more items were excluded from the scale due to insufficiently low loadings on the extracted component. Cronbach's alpha for the final eight-item scale was 0.79. The final MBI-S score was strongly related to that of the MBI-C and a loneliness score as well as moderately related to maladaptive coping. There was no association with respondents' level of education.</p><p><strong>Conclusion: </strong>The MBI-S is a valid short instrument for the assessment of MBI. It has high test economy and measures current neuropsychiatric symptoms and their intensity as a state criterion. Therefore, the MBI-S can be used for the longitudinal measurement of MBI.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"35"},"PeriodicalIF":3.6,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12123818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valentina Baldini, Martina Gnazzo, Giorgia Varallo, Anna Rita Atti, Diana De Ronchi, Andrea Fiorillo, Giuseppe Plazzi
{"title":"Inflammatory markers and suicidal behavior: A comprehensive review of emerging evidence.","authors":"Valentina Baldini, Martina Gnazzo, Giorgia Varallo, Anna Rita Atti, Diana De Ronchi, Andrea Fiorillo, Giuseppe Plazzi","doi":"10.1186/s12991-025-00575-9","DOIUrl":"10.1186/s12991-025-00575-9","url":null,"abstract":"<p><strong>Background: </strong>Suicidal behavior represents a significant public health challenge, and identifying biological markers associated with its risk is critical for prevention and intervention. Emerging evidence suggests a link between inflammation and suicidality, highlighting the role of inflammatory markers as potential biomarkers and therapeutic targets.</p><p><strong>Methods: </strong>We conducted a systematic search across four electronic databases, including PubMed, Web of Science, EMBASE, and PsycINFO, to identify studies examining the association between inflammatory markers (e.g., C-reactive protein, interleukin-6, tumor necrosis factor-alpha) and suicidal ideation or behavior.</p><p><strong>Results: </strong>31 studies met the inclusion criteria. Elevated levels of inflammatory markers were consistently associated with an increased risk of suicidal behavior across diverse populations. This relationship's mechanisms likely involve cytokine-mediated alterations in neurotransmitter systems, neuroplasticity, and stress response pathways. Though robust clinical trials are scarce, preliminary evidence suggests that anti-inflammatory interventions may reduce suicidality.</p><p><strong>Conclusions: </strong>Inflammation appears to play a significant role in the pathophysiology of suicidal behavior, offering promising avenues for biomarker development and novel therapeutic strategies. Future research should prioritize longitudinal studies, standardized methodologies, and exploration of personalized anti-inflammatory treatments to better elucidate the inflammation-suicidality link and enhance clinical applicability.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"36"},"PeriodicalIF":3.6,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prakasini Satapathy, Swastik Subhankar Sahu, Mahalaqua Nazli Khatib, M M Rekha, Mandeep Kaur, Girish Chandra Sharma, Puneet Sudan, K Satyam Naidu, Rajesh Singh, Brajgopal Kushwaha, Tripti Desai, Muhammed Shabil, Sanjay Singh Chauhan, Lokesh Verma, Amritpal Sidhu, Rachana Mehta, Sanjit Sah, Abhay M Gaidhane, Afukonyo Shidoiku Daniel, Joseph Clement Chipeta, Ganesh Bushi
{"title":"Prevalence of eating disorders in aquatic athletes: a systematic review and meta-analysis.","authors":"Prakasini Satapathy, Swastik Subhankar Sahu, Mahalaqua Nazli Khatib, M M Rekha, Mandeep Kaur, Girish Chandra Sharma, Puneet Sudan, K Satyam Naidu, Rajesh Singh, Brajgopal Kushwaha, Tripti Desai, Muhammed Shabil, Sanjay Singh Chauhan, Lokesh Verma, Amritpal Sidhu, Rachana Mehta, Sanjit Sah, Abhay M Gaidhane, Afukonyo Shidoiku Daniel, Joseph Clement Chipeta, Ganesh Bushi","doi":"10.1186/s12991-025-00564-y","DOIUrl":"10.1186/s12991-025-00564-y","url":null,"abstract":"<p><strong>Background: </strong>Aquatic athletes may face unique pressures related to body aesthetics and weight management, potentially increasing their risk of eating disorders (EDs). This systematic review and meta-analysis aimed to estimate the prevalence of EDs in aquatic athletes and assess the quality of the available evidence.</p><p><strong>Methods: </strong>A systematic search was conducted in PubMed, Embase, and Web of Science for studies published in English that reported on the prevalence of EDs among aquatic athletes. After screening and eligibility assessments, eight studies met the inclusion criteria, comprising a total of 715 athletes from various countries, including Poland, Canada, Brazil, Norway, the United States, and the United Kingdom. Quality assessment was performed using an adapted Newcastle-Ottawa Scale (NOS), and a random-effects meta-analysis was conducted to estimate pooled prevalence. Sensitivity analysis and a Doi plot were utilized to evaluate the publication bias.</p><p><strong>Results: </strong>The meta-analysis estimated a pooled prevalence of EDs in aquatic athletes at 27.56% (95% CI: 14.27-46.50%), with a heterogeneity (I²) of 76%, indicating substantial variability in study designs and participant characteristics. Sensitivity analysis confirmed the robustness of the findings, and the Doi plot indicated significant asymmetry (LFK index = -3.44), suggesting potential publication bias or variability across studies.</p><p><strong>Conclusion: </strong>This study revealed a high prevalence of EDs among aquatic athletes. Further research is required on the factors associated with these disorders. Standardized assessment tools and routine screening in aquatic sports settings are recommended to promote early detection and prevention of EDs, ultimately enhancing athlete well-being and performance.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"33"},"PeriodicalIF":3.6,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Crafting wellness: exploring the effectiveness of a single-item mental health measure for young children and their mothers.","authors":"Sıddika Songül Yalçın, Özlem Tezol, Meryem Erat Nergiz, Bülent Güneş, Adnan Barutçu, Emel Kabakoğlu Ünsür, Nalan Karabayır, Zeynep Yılmaz Öztorun, Habip Almiş","doi":"10.1186/s12991-025-00573-x","DOIUrl":"10.1186/s12991-025-00573-x","url":null,"abstract":"<p><strong>Background: </strong>Recognizing the integral role of parental emotional and behavioral health in shaping a supportive family environment crucial for a child's emotional well-being, a practical tool for evaluating mental health in both preschool children and their mothers are necessary. In this methodological study conducted across eight provinces in Turkey, we aimed to develop and assess the psychometric properties of a single-item mental health measure for physically healthy children aged 2-5 years and their mothers.</p><p><strong>Method: </strong>The study included 411 child-mother pairs recruited from tertiary care hospitals, with subjects selected from well-child departments. Various psychometric assessments were employed, including the Strengths and Difficulties Questionnaire (SDQ) for children, Depression, Anxiety, and Stress Scale (DASS-21), Patient Health Questionnaire-4 (PHQ-4) for mothers, and single-item measures for both child and maternal mental health [mother-reported mental health of child (MRCMH) and self-reported mental health of mother (SRMH)]. Data were collected at two time points: baseline evaluation for validity testing and test-retest evaluation at the 3rd week.</p><p><strong>Results: </strong>The MRCMH indicated excellent validity, with sensitivity and specificity for detecting borderline and abnormal mental health difficulties in children at 90%, 100%, and 83%, respectively. The SRMH revealed sensitivity and specificity of 62% and 78% for identifying maternal depression, 57% and 76% for anxiety, 63% and 76% for stress, and 54% and 87% for psychological distress, respectively. Construct validity analyses revealed significant correlations between MRCMH and SDQ scores, as well as between SRMH and DASS-21 and PHQ-4 scores. Test-retest reliability, assessed through intraclass correlation coefficients, indicated varying agreement levels, with the highest agreement observed for SDQ total difficulties and the lowest for SRMH. Further exploration of the measures' sensitivity and specificity revealed noteworthy accuracy in detecting child mental difficulties and maternal psychological distress. Correlational analyses between baseline and 3-week scores highlighted the stability of MRCMH and SRMH over time.</p><p><strong>Conclusion: </strong>This research contributes valuable insights into the psychometric properties of single-item measures for child and maternal mental health, offering a potential tool for clinicians and researchers. The outcomes can inform public health strategies and interventions aimed at promoting positive mental health outcomes in preschool children and their mothers.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"34"},"PeriodicalIF":3.6,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jianwei Wu, Yuan Liu, Tan Hung, Simin Liu, Sydney X Hu
{"title":"Parental dysfunction and adolescent mental health: AI-aided content analysis of suicide notes on social media.","authors":"Jianwei Wu, Yuan Liu, Tan Hung, Simin Liu, Sydney X Hu","doi":"10.1186/s12991-025-00568-8","DOIUrl":"10.1186/s12991-025-00568-8","url":null,"abstract":"<p><p>Adolescent suicide represents a critical global health issue. While research has identified numerous risk factors, the specific impact of parental dysfunction on adolescent suicide remains understudied, especially in Chinese contexts. This study explores how parental dysfunction manifests in suicide notes and affects adolescent mental health. We collected data from Chinese social media platforms using web crawlers, yielding 30 valid suicide notes for analysis. Using the AI-aided content analysis platform DiVoMiner<sup>®</sup>, we conducted high-frequency word and semantic network analyses. Our findings reveal that parents are a central concern for suicidal youth. We identified three primary patterns of parental dysfunction: excessive emphasis on instrumental goals, neglect of basic emotional needs, and inadequate protection from life traumas. These dysfunctions contribute to severe psychological distress, identity loss, and negative coping behaviors among youth. The research highlights two significant phenomena in contemporary Chinese family dynamics: the \"short-sightedness\" of prioritizing short-term instrumental goals over long-term social-emotional development, and the remarkably high prevalence of \"lack of autonomy\" in parenting approaches. Our study extends the literature by exploring mechanisms through which parental dysfunctions contribute to suicidal behaviors in young people. These findings emphasize the need for collaborative efforts among parents, educators, policymakers, and mental health professionals to foster nurturing environments characterized by emotional support, autonomy encouragement, and balanced academic expectations-all crucial for adolescent well-being.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"32"},"PeriodicalIF":3.6,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Fagiolini, Lea Dolenc Grošelj, Marina Šagud, Ante Silić, Milan Latas, Čedo D Miljević, Alessandro Cuomo
{"title":"Targeting heterogeneous depression with trazodone prolonged release: from neuropharmacology to clinical application.","authors":"Andrea Fagiolini, Lea Dolenc Grošelj, Marina Šagud, Ante Silić, Milan Latas, Čedo D Miljević, Alessandro Cuomo","doi":"10.1186/s12991-025-00563-z","DOIUrl":"10.1186/s12991-025-00563-z","url":null,"abstract":"<p><strong>Aim: </strong>This paper evaluates the clinical efficacy, safety, and practical implications of Trazodone Prolonged Release (PR) in managing depression, anxiety, and sleep disorders, with a focus on its multimodal mechanism of action and advantages over traditional therapies.</p><p><strong>Methodology: </strong>A critical review of recent literature (2020-2024) [1-3] was conducted, analyzing data from clinical trials, real-world studies, and European treatment guidelines to assess the pharmacodynamics, pharmacokinetics, and therapeutic outcomes of Trazodone PR.</p><p><strong>Results: </strong>Trazodone PR demonstrates efficacy in addressing complex symptoms of depression, anxiety, and sleep disturbances, with a favorable safety profile and reduced risk of sexual dysfunction and weight gain compared to other antidepressants. Its ability to modulate serotonin, norepinephrine, dopamine, and histamine systems enhances mood, sleep quality, and cognitive recovery.</p><p><strong>Conclusion: </strong>Trazodone PR is a versatile and well-tolerated treatment option for patients with comorbid conditions and treatment-resistant cases. Its multimodal action, combined with benefits like improved neuroplasticity through BDNF production, makes it a suitable choice for the long-term management of mood disorders and associated conditions [4-6].</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"31"},"PeriodicalIF":3.6,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12096638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tao Yang, Wei Chen, Qiaodan Lu, Qiufen Meng, Haiyan Liu
{"title":"Evaluating the PCL-5 in China: new insights from its assessments over time and gender invariance.","authors":"Tao Yang, Wei Chen, Qiaodan Lu, Qiufen Meng, Haiyan Liu","doi":"10.1186/s12991-025-00567-9","DOIUrl":"10.1186/s12991-025-00567-9","url":null,"abstract":"<p><strong>Background: </strong>In the latest research, it is proposed that the intrusions symptoms of the structure of post-traumatic stress disorder (PTSD) were divided into internally-generated and externally-generated. Additional research is required to validate this emerging theory. Moreover, few studies have employed longitudinal data to further validate the novel 8-factor model.</p><p><strong>Aim: </strong>This study aims to explore the factor structure, gender invariance, and longitudinal invariance of the PTSD Checklist for DSM-5 (PCL-5) among children in post-pandemic era.</p><p><strong>Methods: </strong>A survey was conducted on 1861 children using the PTSD Checklist for DSM-5 (PCL-5), and 590 children were re-investigated over three months interval. The statistical analysis includes: Kolmogorov-Smirnov normality test, the missing rates and descriptive statistics of the study variables, confirmatory factor analysis, the gender measurement invariance, longitudinal measurement invariance, and correlation of each factor within the PCL-5.</p><p><strong>Results: </strong>Based on the DSM-5 criteria, the results indicated that 6.8% of the children in the sample exhibited symptoms suggestive of possible PTSD. The novel 8-factor model fits better than the DSM-5 model, DSM-5 dysphoric model, Dysphoric arousal model, Anhedonia model, Externalizing behaviors model, and Hybrid model. The measurement invariance results further indicated that the PCL-5 has strict invariance across gender and strong invariance across time.</p><p><strong>Conclusion: </strong>This study validated the novel 8-factor model of DSM-5 PTSD among children in the post-pandemic era and assessed the gender and longitudinal measurement invariance of the PCL-5. The novel 8-factor model of the PCL-5 is the best DSM-5 model of PTSD symptoms and has strict measurement invariance across gender and strong measurement invariance across time. The research results extended the theoretical framework and empirical research on the DSM-5 PTSD novel 8-factor model. Through this analysis, we hope to provide more accurate tools and strategies for the evaluation and intervention of post-traumatic stress disorder in children.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"29"},"PeriodicalIF":3.6,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12087212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144100995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Accelerated repetitive transcranial magnetic stimulation in the treatment of depressive disorder resistant to a course of antidepressant medication.","authors":"Mahtab Motamed, Azin Fathi, Arman Hajikarim-Hamedani, Javad Alaghband-Rad","doi":"10.1186/s12991-025-00572-y","DOIUrl":"10.1186/s12991-025-00572-y","url":null,"abstract":"<p><strong>Aims: </strong>It is generally known that 30% of Major depressive disorder (MDD) patients do not respond to traditional pharmacological and psychosocial therapy. Transcranial magnetic stimulation (TMS), introduced first in 1985, was a non-invasive neural network research method. Later, repetitive Transcranial Magnetic Stimulation (rTMS) was approved by the FDA to treat treatment-resistant depression (TRD) in 2008. Over the past two decades, rTMS has been extensively developed using various protocols in order to stimulate superficial brain nerve cells non-invasively. We planned to see if high-frequency accelerated left prefrontal rTMS can improve symptoms of treatment resistant depression given its convenience it provides by having patients for fewer treatment sessions.</p><p><strong>Methods: </strong>A total of 25 patients were enrolled in the study. Inclusion criteria were age between 18 and 60 and a history of at least one failed treatment with antidepressants. The treatment was conducted over six days scattered over three weeks and each day consisted of three 30-minute sessions (83, 83, and 84 trains for each session). The sessions were separated with 15-minute breaks. rTMS protocol: 120% of the motor threshold and frequency of 10 Hz. Consisting of 2.4 s trains with an intertrain interval of 15-seconds.</p><p><strong>Result: </strong>The study included 25 individuals (male: 12/13) with an average age of 36.88 ± 10.61. We compared outcome indicators at baseline and week three after confirming the normality of the data. After three weeks, Hamilton Depression Rating Scale and Clinician Global Impression showed a substantial improvement. There was a remission rate of 24% (6/25) and a response rate of 52% (13/25).</p><p><strong>Conclusion: </strong>This work adds to the evidence that rTMS can treat TRD and shows that a more convenient high-frequency accelerated rTMS can improve symptoms in treatment resistant depression.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"30"},"PeriodicalIF":3.6,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144100985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yu-Min Zhang, Xiao-Mei Jiang, Ya Xie, Nan Lang, Min-Lu Liang, Pei Zhang, Li-Chen OuYang, Zhang-Wei Lv, Cong-Wei Liu, Li-Ping Zhang, Chun Wang
{"title":"Interactions of factors in self-injuries among enrolled students: a network approach.","authors":"Yu-Min Zhang, Xiao-Mei Jiang, Ya Xie, Nan Lang, Min-Lu Liang, Pei Zhang, Li-Chen OuYang, Zhang-Wei Lv, Cong-Wei Liu, Li-Ping Zhang, Chun Wang","doi":"10.1186/s12991-025-00570-0","DOIUrl":"10.1186/s12991-025-00570-0","url":null,"abstract":"<p><strong>Purpose: </strong>Suicidal and non-suicidal self-injuries are types of self-directed violence that can become complex health issues. This study assessed how and to what degree the factors of self-injuries are interrelated among enrolled students.</p><p><strong>Methods: </strong>A total of 1481 students were recruited from college and middle or secondary schools, and 1465 (98.92%) subjects comprised the final sample. Mixed graphical models were used to establish network structures. Also explore their shortest paths and conduct a regression analysis.</p><p><strong>Results: </strong>Of the 1465 students, we observed intersections that connected the cluster of early experiences and psychiatric/psychological using network analysis. Shortest paths analysis and regression analysis suggest that symptoms of schizoid (edge-weights = 0.336, OR = 2.79, p < 0.01) and narcissistic (edge-weights=-0.177, OR = 0.35, p < 0.05) personality disorders (PD), acceptance (edge-weights = 0.470, OR = 12.80, p < 0.01) and positive refocusing (edge-weights=-0.171, OR = 0.12, p < 0.05) strategies of emotion-regulation, mindfulness awareness (edge-weights=-0.263, OR = 0.24, p < 0.05), and emotional-neglect in childhood (edge-weights = 0.239, OR = 5.54, p < 0.05) were found with non-suicidal self-injury (NSSI). Symptoms of anxiety (edge-weights = 0.280, OR = 2.00, p < 0.01) and avoidant-PD (edge-weights = 0.229, OR = 1.75, p < 0.01) were associated with suicidal ideation, and symptoms of borderline-PD (edge-weights = 0.432, OR = 5.38, p < 0.05) and mindfulness awareness (edge-weights=-0.180, OR = 0.28, p < 0.05) were associated with suicide attempt.</p><p><strong>Conclusions: </strong>Relying exclusively on acceptance strategy may constitute an avoidance pattern, impeding the ability to confront emotional distress. Clinical intervention aimed at repairing father-child relationship may be helpful to recover from emotional trauma and improve current symptoms and self-injuries.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"28"},"PeriodicalIF":3.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cong Zhou, Shanling Ji, Aoxue Zhang, Hao Yu, Chuanxin Liu, Sen Li
{"title":"Bibliometric and visual analysis of circadian rhythms in depression from 2004 to 2024.","authors":"Cong Zhou, Shanling Ji, Aoxue Zhang, Hao Yu, Chuanxin Liu, Sen Li","doi":"10.1186/s12991-025-00565-x","DOIUrl":"https://doi.org/10.1186/s12991-025-00565-x","url":null,"abstract":"<p><strong>Introduction: </strong>Understanding the intricate relationship between circadian rhythms and depression is crucial for developing effective interventions and treatments for individuals affected by depression. Circadian rhythms regulate various physiological and behavioral processes, while depression manifests as persistent feelings of sadness and disturbances in sleep, appetite, and energy levels. Emerging research suggests a significant interplay between circadian rhythm disruption and depression, highlighting the need for comprehensive analysis in this area.</p><p><strong>Methodology: </strong>A bibliometric and visual analysis of literature on circadian rhythms in depression from 2004 to 2024 was conducted using the Web of Science Core Collection. Data were analyzed using bibliometric tools including VOSviewer, CiteSpace, and Bibliometrix to identify publication trends, geographical distribution, authorship patterns, institutional collaborations, journal preferences, keyword co-occurrence, and highly cited references.</p><p><strong>Results: </strong>Analysis revealed a steady increase in publications and citations related to circadian rhythms in depression. The United States emerged as the leading contributor, with strong global collaborations. Key journals included Chronobiology International and Journal of Affective Disorders. Top keywords included circadian rhythm, depression, sleep, melatonin, and bipolar disorder. The most cited article is a review titled \"Practice parameters for the indications for polysomnography and related procedures: An update for 2005\".</p><p><strong>Conclusions: </strong>This study offers a comprehensive overview of research on circadian rhythms in depression, highlighting key trends, contributors, and interdisciplinary intersections.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"27"},"PeriodicalIF":3.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}