Annals of General Psychiatry最新文献

{"title":"The relationship among hopelessness, suicide risk, body mass index and eating motivations in major depressive disorder comorbid with obesity: a case-control study.","authors":"Fatma Gül Helvacı Çelik, Meltem Hazel Şimşek, Meltem Puşuroğlu, Ulaş Korkmaz","doi":"10.1186/s12991-025-00580-y","DOIUrl":"10.1186/s12991-025-00580-y","url":null,"abstract":"<p><strong>Objective: </strong>Major Depressive Disorder (MDD) is a significant mental health problem, frequently comorbid with both physical and psychiatric disorders. The association between MDD and obesity is not fully understood. Eating motivations (EMs), which relate to why and how individuals choose to eat, may be associated with disorders like obesity and MDD. Hopelessness and suicidal ideation are common symptoms of MDD. This study aimed to evaluate the relationship between EMs, depression, body mass index (BMI), hopelessness, and suicidal ideation in normal-weight and obese MDD groups compared to healthy controls.</p><p><strong>Method: </strong>The study included 50 patients with MDD and normal weight (BMI 18.5-24.9), 50 patients with MDD and obesity (BMI > 30), and 50 healthy control participants (BMI 18.5-24.9). The majority of participants were women (74% in obese MDD, 70% in normal-weight MDD, 56% in the control group). The age of the groups was similar for the normal-weight MDD and control groups, but the obese MDD group was older (control: 32.72 ± 10.07, normal-weight MDD 33.42 ± 10.24, obese MDD 39.52 ± 10.67, p = 0.002). Regarding BMI, it was as follows: control: 21.61 ± 1.92, normal-weight MDD 23.54 ± 3.60, and obese MDD 35.30 ± 5.07. Sociodemographic data form, Beck Depression Inventory, Beck Hopelessness Inventory, Suicide Ideation Scale and Eating Motivation Questionnaire were administered.</p><p><strong>Results: </strong>No significant differences were found between the MDD groups in terms of Beck Depression Inventory (BDI), Beck Hopelessness Inventory (BHI), and Suicidal Ideation Scale (SIS) scores. Significant differences were observed among all groups in most subtypes of EMs. In the obese MDD group, habits, traditional eating, price, visual appeal, and affect regulation were correlated with suicide attempts. Only traditional eating remained associated with suicide attempts, where a one-unit increase in the traditional eating score explained a 0.724-unit increase in suicide attempts. Additionally, emotion regulation was a significant predictor of suicidal ideation in the obese MDD group, where a one-unit increase in emotion regulation explained a 0.885-unit increase in suicidal ideation.</p><p><strong>Conclusions: </strong>The differentiation between suicidal ideation and EMs in obese and normal-weight MDD groups is crucial. The observed differences in EMs among the three groups with similar sociocultural characteristics are noteworthy. Clinicians should assess eating motivations as part of suicide risk evaluations in patients with comorbid MDD and obesity. Longitudinal studies are needed to clarify causal relationships between these variables.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"43"},"PeriodicalIF":3.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12224497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144558889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of sleep problems with suicidal behaviors and healthcare utilization in adults with chronic diseases: the role of mental illness.","authors":"Chen Wen, Zheng Wei, Nasr Chalghaf, Woldegebriel Assefa Woldegerima, Jianhong Wu, Nicola Luigi Bragazzi, Sergio Garbarino","doi":"10.1186/s12991-025-00576-8","DOIUrl":"10.1186/s12991-025-00576-8","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the association between sleep problems and suicidal behaviors as well as healthcare utilization in Canadian adults with chronic diseases, while also examining the mediating role of mental illness.</p><p><strong>Methods: </strong>Data were drawn from the 2015-16 cycle of the Canadian Community Health Survey, specifically from Ontario, Manitoba, and Saskatchewan - the provinces that included the optional sleep module. A total of 22,700 participants aged ≥ 18 years and diagnosed with at least one chronic disease were included in the analysis. Sleep problems were defined as extreme sleep durations (either < 5 or ≥ 10 h) and insomnia. Mental illness was classified as a self-reported mood or anxiety disorder.</p><p><strong>Results: </strong>Participants with extreme sleep durations (compared to 7 to < 8 h) and those with insomnia (compared to no insomnia) showed a higher prevalence of suicidal ideation, suicidal plans, and increased healthcare utilization. After adjusting for multiple covariates, both extreme sleep durations and insomnia remained significantly associated with increased odds of suicidal ideation, suicidal plans, and healthcare utilization. Mediation analyses indicated that mental illness partially mediated these associations.</p><p><strong>Conclusions: </strong>Both extreme sleep durations and insomnia were independently associated with higher odds of suicidal behaviors and increased healthcare utilization in adults with chronic diseases, with mental illness playing a partial mediating role in these relationships.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"40"},"PeriodicalIF":3.6,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144339848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and risk factors of hypothyroidism in psychiatric outpatients with long-term lithium treatment: a 10-year retrospective hospital-based study.","authors":"Kanthee Anantapong, Chavisa Jittpratoom, Jarurin Pitanupong","doi":"10.1186/s12991-025-00578-6","DOIUrl":"10.1186/s12991-025-00578-6","url":null,"abstract":"<p><strong>Background: </strong>The study aimed to assess the incidence of lithium-induced hypothyroidism and its associated factors in psychiatric outpatients on long-term lithium therapy.</p><p><strong>Methods: </strong>A retrospective study at Songklanagarind Hospital (January 1, 2013, to September 30, 2022) focused on clinical (overt) and subclinical forms of lithium-induced hypothyroidism. Subclinical hypothyroidism, characterised by elevated thyroid stimulating hormone (TSH) but normal thyroxine (FT4) levels, and clinical hypothyroidism, by low FT4 and high TSH, were analysed. Patients with less than 3 months of lithium therapy or prior thyroid conditions were excluded. We used survival analysis and logistic regression to investigate incidence and factors.</p><p><strong>Results: </strong>Among 461 on lithium maintenance therapy, 279 outpatients met the inclusion criteria; however, only 166 (59%) were monitored for thyroid functions during the study period and included in the final analyses, mostly female (53.6%) with bipolar disorder (72.9%), median age 42.0 years. The median duration of maintenance therapy was 3.7 years (IQR = 1.0-9.3). Over a decade, 30 patients developed lithium-induced hypothyroidism, primarily subclinical (28 cases), at an incidence rate of 0.0212 cases per patient-year. Hypothyroidism manifested after 14.4 months of lithium therapy (IQR = 5.2-53.2), with a prominent decline of survival curve within the first year. Younger age (adjusted OR = 0.95, P = 0.001), presence of physical comorbidities (adjusted OR = 2.69, P = 0.039), and higher lithium levels (P = 0.003) were associated with hypothyroidism.</p><p><strong>Conclusions: </strong>Despite low incidence, regular thyroid monitoring is advised for patients on lithium. The study identifies risk factors for lithium-induced hypothyroidism, aiding in patient risk assessment and monitoring protocols.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"39"},"PeriodicalIF":3.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suicide risk in persons with polycystic ovarian syndrome: a systematic review.","authors":"Sabrina Wong, Gia Han Le, Heidi Ka Ying Lo, Bing Cao, Poh Khuen Lim, Taeho Greg Rhee, Roger Ho, Hernan F Guillen-Burgos, Kayla M Teopiz, Lee Phan, Joshua D Rosenblat, Melanie Zhang, Roger S McIntyre","doi":"10.1186/s12991-025-00574-w","DOIUrl":"10.1186/s12991-025-00574-w","url":null,"abstract":"<p><strong>Background: </strong>Polycystic ovarian syndrome (PCOS) is a common and increasingly prevalent reproductive and metabolic endocrine disorder that is characterized by metabolic alterations, hyperandrogenism, menstrual irregularities as well as an increased risk of depression. Available evidence suggests PCOS may also be associated with disparate aspects of suicidality. Herein, we sought to determine the prevalence of suicidal ideation, suicidal behaviours and completed suicide in the PCOS population.</p><p><strong>Methods: </strong>We systematically searched PubMed, Ovid and Scopus databases from inception to January 7, 2024. A manual search was conducted on Google Scholar. Two reviewers independently screened the retrieved studies against the eligibility criteria (S.W. and G.H.L.). Human studies investigating suicide outcomes in women of reproductive age with a confirmed diagnosis of PCOS were included.</p><p><strong>Results: </strong>Eleven studies meeting our eligibility criteria were included. Although results were mixed, available evidence suggests that persons with PCOS are at an increased risk of suicidal ideation, self-harm and suicide attempts and are also differentially affected by psychiatric comorbidities (e.g., depressive disorders). Notwithstanding, suicide risk was not fully accounted for by the presence of mental illness, which suggests that PCOS may also be contributory.</p><p><strong>Conclusion: </strong>PCOS is associated with an increased risk of suicidal ideation and behaviour and associated psychiatric comorbidities. Persons with PCOS should be routinely evaluated for the presence of clinically significant suicidality. Whether increased suicidality in PCOS populations is a direct effect of the disease state and/or is largely moderated by psychiatric comorbidity is a future research vista.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"38"},"PeriodicalIF":3.6,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12128235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory chemokines in adolescents' suicide state with depressive disorders.","authors":"Hongyu Zheng, Wenyuan Liu, Binbin Chen, Shuwen Hu, Daming Mo, Pengfei Guo, Xiaolu Jiang, Rong Yang, Shuo Wang, Hui Zhong","doi":"10.1186/s12991-025-00571-z","DOIUrl":"10.1186/s12991-025-00571-z","url":null,"abstract":"<p><p>Suicide has become one of the leading causes of death in adolescents and is a direct consequence in patients with depressive disorders. Recently, neuroinflammation has been shown to play a role in the development of depression. This study examined serum chemokine levels in adolescents with depressive disorders at different suicide stages to identify chemokines that discriminate between suicidal behaviors. This study enrolled 111 adolescent patients with depressive disorders who were further subdivided into three groups based on the presence of suicidal behavior or ideation: suicide attempt group (n = 45), suicidal ideation group (n = 44), and non-suicidal depression group (n = 22), along with 23 healthy controls. Eight inflammatory chemokines were detected using the mesoscale discovery method. Patients in the suicide attempters group had higher levels of IL8, MCP-1, Eotaxin, and Eotaxin-3 than those in the non-suicide depression group. Eotaxin-2 had the greatest effect on suicidal behaviors of all factors.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"37"},"PeriodicalIF":3.6,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12125890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Mild Behavioral Impairment Scale (MBI-S) for brief self-assessment of Mild Behavioral Impairment in people without dementia.","authors":"Paula Hinkl, Elmar Graessel, Nicolas Rohleder, Peter Landendoerfer, Thomas Kuehlein, Natascha Lauer, Anna Pendergrass","doi":"10.1186/s12991-025-00566-w","DOIUrl":"10.1186/s12991-025-00566-w","url":null,"abstract":"<p><strong>Background: </strong>Mild Cognitive Impairment (MCI) and Mild Behavioral Impairment (MBI) are important constructs in the context of cognitive decline. MBI can be assessed with the Mild Behavioral Impairment Checklist (MBI-C). However, the instrument has deficits in psychometrics and content, thus indicating a need for improvement. The aim of this study was to develop a complementary short instrument, the Mild Behavioral Impairment Scale (MBI-S), designed to measure MBI as a short-term modifiable state criterion, and to validate it in a non-clinical sample of people 18 years of age or older.</p><p><strong>Methods: </strong>Most of the items on the MBI-S stem from the MBI-C and were chosen to represent the dimensions of the Neuropsychiatric Inventory Questionnaire. The MBI-S was validated on self-reported data from 175 individuals. In an item analysis, the discriminatory power and item difficulties were examined. Cronbach's alpha was calculated to assess the internal consistency, and a principal component analysis was conducted to determine the structure of the instrument. Construct validity was established by testing four hypotheses about relationships between the MBI-S and other instruments by calculating correlation coefficients.</p><p><strong>Results: </strong>After the item analysis, two items were removed from the final version of the scale on the basis of insufficient discriminatory power and the finding that the internal consistency of the total score increased when the items were deleted. The principal component analysis yielded a single-component structure for the MBI-S. Two more items were excluded from the scale due to insufficiently low loadings on the extracted component. Cronbach's alpha for the final eight-item scale was 0.79. The final MBI-S score was strongly related to that of the MBI-C and a loneliness score as well as moderately related to maladaptive coping. There was no association with respondents' level of education.</p><p><strong>Conclusion: </strong>The MBI-S is a valid short instrument for the assessment of MBI. It has high test economy and measures current neuropsychiatric symptoms and their intensity as a state criterion. Therefore, the MBI-S can be used for the longitudinal measurement of MBI.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"35"},"PeriodicalIF":3.6,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12123818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crafting wellness: exploring the effectiveness of a single-item mental health measure for young children and their mothers.","authors":"Sıddika Songül Yalçın, Özlem Tezol, Meryem Erat Nergiz, Bülent Güneş, Adnan Barutçu, Emel Kabakoğlu Ünsür, Nalan Karabayır, Zeynep Yılmaz Öztorun, Habip Almiş","doi":"10.1186/s12991-025-00573-x","DOIUrl":"10.1186/s12991-025-00573-x","url":null,"abstract":"<p><strong>Background: </strong>Recognizing the integral role of parental emotional and behavioral health in shaping a supportive family environment crucial for a child's emotional well-being, a practical tool for evaluating mental health in both preschool children and their mothers are necessary. In this methodological study conducted across eight provinces in Turkey, we aimed to develop and assess the psychometric properties of a single-item mental health measure for physically healthy children aged 2-5 years and their mothers.</p><p><strong>Method: </strong>The study included 411 child-mother pairs recruited from tertiary care hospitals, with subjects selected from well-child departments. Various psychometric assessments were employed, including the Strengths and Difficulties Questionnaire (SDQ) for children, Depression, Anxiety, and Stress Scale (DASS-21), Patient Health Questionnaire-4 (PHQ-4) for mothers, and single-item measures for both child and maternal mental health [mother-reported mental health of child (MRCMH) and self-reported mental health of mother (SRMH)]. Data were collected at two time points: baseline evaluation for validity testing and test-retest evaluation at the 3rd week.</p><p><strong>Results: </strong>The MRCMH indicated excellent validity, with sensitivity and specificity for detecting borderline and abnormal mental health difficulties in children at 90%, 100%, and 83%, respectively. The SRMH revealed sensitivity and specificity of 62% and 78% for identifying maternal depression, 57% and 76% for anxiety, 63% and 76% for stress, and 54% and 87% for psychological distress, respectively. Construct validity analyses revealed significant correlations between MRCMH and SDQ scores, as well as between SRMH and DASS-21 and PHQ-4 scores. Test-retest reliability, assessed through intraclass correlation coefficients, indicated varying agreement levels, with the highest agreement observed for SDQ total difficulties and the lowest for SRMH. Further exploration of the measures' sensitivity and specificity revealed noteworthy accuracy in detecting child mental difficulties and maternal psychological distress. Correlational analyses between baseline and 3-week scores highlighted the stability of MRCMH and SRMH over time.</p><p><strong>Conclusion: </strong>This research contributes valuable insights into the psychometric properties of single-item measures for child and maternal mental health, offering a potential tool for clinicians and researchers. The outcomes can inform public health strategies and interventions aimed at promoting positive mental health outcomes in preschool children and their mothers.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"34"},"PeriodicalIF":3.6,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental dysfunction and adolescent mental health: AI-aided content analysis of suicide notes on social media.","authors":"Jianwei Wu, Yuan Liu, Tan Hung, Simin Liu, Sydney X Hu","doi":"10.1186/s12991-025-00568-8","DOIUrl":"10.1186/s12991-025-00568-8","url":null,"abstract":"<p><p>Adolescent suicide represents a critical global health issue. While research has identified numerous risk factors, the specific impact of parental dysfunction on adolescent suicide remains understudied, especially in Chinese contexts. This study explores how parental dysfunction manifests in suicide notes and affects adolescent mental health. We collected data from Chinese social media platforms using web crawlers, yielding 30 valid suicide notes for analysis. Using the AI-aided content analysis platform DiVoMiner^®, we conducted high-frequency word and semantic network analyses. Our findings reveal that parents are a central concern for suicidal youth. We identified three primary patterns of parental dysfunction: excessive emphasis on instrumental goals, neglect of basic emotional needs, and inadequate protection from life traumas. These dysfunctions contribute to severe psychological distress, identity loss, and negative coping behaviors among youth. The research highlights two significant phenomena in contemporary Chinese family dynamics: the \"short-sightedness\" of prioritizing short-term instrumental goals over long-term social-emotional development, and the remarkably high prevalence of \"lack of autonomy\" in parenting approaches. Our study extends the literature by exploring mechanisms through which parental dysfunctions contribute to suicidal behaviors in young people. These findings emphasize the need for collaborative efforts among parents, educators, policymakers, and mental health professionals to foster nurturing environments characterized by emotional support, autonomy encouragement, and balanced academic expectations-all crucial for adolescent well-being.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"32"},"PeriodicalIF":3.6,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the PCL-5 in China: new insights from its assessments over time and gender invariance.","authors":"Tao Yang, Wei Chen, Qiaodan Lu, Qiufen Meng, Haiyan Liu","doi":"10.1186/s12991-025-00567-9","DOIUrl":"10.1186/s12991-025-00567-9","url":null,"abstract":"<p><strong>Background: </strong>In the latest research, it is proposed that the intrusions symptoms of the structure of post-traumatic stress disorder (PTSD) were divided into internally-generated and externally-generated. Additional research is required to validate this emerging theory. Moreover, few studies have employed longitudinal data to further validate the novel 8-factor model.</p><p><strong>Aim: </strong>This study aims to explore the factor structure, gender invariance, and longitudinal invariance of the PTSD Checklist for DSM-5 (PCL-5) among children in post-pandemic era.</p><p><strong>Methods: </strong>A survey was conducted on 1861 children using the PTSD Checklist for DSM-5 (PCL-5), and 590 children were re-investigated over three months interval. The statistical analysis includes: Kolmogorov-Smirnov normality test, the missing rates and descriptive statistics of the study variables, confirmatory factor analysis, the gender measurement invariance, longitudinal measurement invariance, and correlation of each factor within the PCL-5.</p><p><strong>Results: </strong>Based on the DSM-5 criteria, the results indicated that 6.8% of the children in the sample exhibited symptoms suggestive of possible PTSD. The novel 8-factor model fits better than the DSM-5 model, DSM-5 dysphoric model, Dysphoric arousal model, Anhedonia model, Externalizing behaviors model, and Hybrid model. The measurement invariance results further indicated that the PCL-5 has strict invariance across gender and strong invariance across time.</p><p><strong>Conclusion: </strong>This study validated the novel 8-factor model of DSM-5 PTSD among children in the post-pandemic era and assessed the gender and longitudinal measurement invariance of the PCL-5. The novel 8-factor model of the PCL-5 is the best DSM-5 model of PTSD symptoms and has strict measurement invariance across gender and strong measurement invariance across time. The research results extended the theoretical framework and empirical research on the DSM-5 PTSD novel 8-factor model. Through this analysis, we hope to provide more accurate tools and strategies for the evaluation and intervention of post-traumatic stress disorder in children.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"29"},"PeriodicalIF":3.6,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12087212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144100995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interactions of factors in self-injuries among enrolled students: a network approach.","authors":"Yu-Min Zhang, Xiao-Mei Jiang, Ya Xie, Nan Lang, Min-Lu Liang, Pei Zhang, Li-Chen OuYang, Zhang-Wei Lv, Cong-Wei Liu, Li-Ping Zhang, Chun Wang","doi":"10.1186/s12991-025-00570-0","DOIUrl":"10.1186/s12991-025-00570-0","url":null,"abstract":"<p><strong>Purpose: </strong>Suicidal and non-suicidal self-injuries are types of self-directed violence that can become complex health issues. This study assessed how and to what degree the factors of self-injuries are interrelated among enrolled students.</p><p><strong>Methods: </strong>A total of 1481 students were recruited from college and middle or secondary schools, and 1465 (98.92%) subjects comprised the final sample. Mixed graphical models were used to establish network structures. Also explore their shortest paths and conduct a regression analysis.</p><p><strong>Results: </strong>Of the 1465 students, we observed intersections that connected the cluster of early experiences and psychiatric/psychological using network analysis. Shortest paths analysis and regression analysis suggest that symptoms of schizoid (edge-weights = 0.336, OR = 2.79, p < 0.01) and narcissistic (edge-weights=-0.177, OR = 0.35, p < 0.05) personality disorders (PD), acceptance (edge-weights = 0.470, OR = 12.80, p < 0.01) and positive refocusing (edge-weights=-0.171, OR = 0.12, p < 0.05) strategies of emotion-regulation, mindfulness awareness (edge-weights=-0.263, OR = 0.24, p < 0.05), and emotional-neglect in childhood (edge-weights = 0.239, OR = 5.54, p < 0.05) were found with non-suicidal self-injury (NSSI). Symptoms of anxiety (edge-weights = 0.280, OR = 2.00, p < 0.01) and avoidant-PD (edge-weights = 0.229, OR = 1.75, p < 0.01) were associated with suicidal ideation, and symptoms of borderline-PD (edge-weights = 0.432, OR = 5.38, p < 0.05) and mindfulness awareness (edge-weights=-0.180, OR = 0.28, p < 0.05) were associated with suicide attempt.</p><p><strong>Conclusions: </strong>Relying exclusively on acceptance strategy may constitute an avoidance pattern, impeding the ability to confront emotional distress. Clinical intervention aimed at repairing father-child relationship may be helpful to recover from emotional trauma and improve current symptoms and self-injuries.</p>","PeriodicalId":7942,"journal":{"name":"Annals of General Psychiatry","volume":"24 1","pages":"28"},"PeriodicalIF":3.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}