Annales de biologie clinique最新文献_第6页

Reports of the Match 180 seconds from the French-speaking Days of Medical Biology 《医学生物学法语日》180秒比赛报道

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2022-11-01 DOI: 10.1684/abc.2022.1770

Marie-Hélène Tournoys, Amélie Bachelot, Bruno Baudin, Oulfa Boussetta-Charfi, Julie Catillon, Emma Chambery, Anne-Laure Demartin, Nesrine Ktari, Aurélie Truffot, Jules Weinhard, Sabine Zaepfel, Jérôme Grosjean, Carole Poupon

引用次数: 0

Lower-back pain and weight loss in a 75-year-old man 一名75岁男子的腰痛和体重减轻

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2022-11-01 DOI: 10.1684/abc.2022.1768

Aurélie Sarthou, Céline Bouchet-Seraphin, Maria-Margarita Hurtado-Nedelec, Katell Peoc’h

引用次数: 0

POCT management of neonatal bilirubinemia – guidelines for an optimization of kernicterus monitoring 新生儿胆红素血症POCT管理-核黄疸监测优化指南

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2022-11-01 DOI: 10.1684/abc.2022.1774

Michel Vaubourdolle, Agnès Mailloux

{"title":"POCT management of neonatal bilirubinemia – guidelines for an optimization of kernicterus monitoring","authors":"Michel Vaubourdolle, Agnès Mailloux","doi":"10.1684/abc.2022.1774","DOIUrl":"https://doi.org/10.1684/abc.2022.1774","url":null,"abstract":"In pediatrics, accurate measurement of total serum bilirubin (TSB) is of major importance for reliable diagnosis and appropriate management of neonatal jaundice. However, several studies evidenced poor comparability of results obtained with the different available methods either in central lab or in POCT, on serum, capillary blood or transcutaneous. This situation is partly due to the lack of Reference Materials, especially for high bilirubin concentrations but also on poor communication between central lab and neonatology unit. To progress on these issues, we have compiled some data from CNRHP to propose guidelines for choice, use and management of POCT devices and to help clinical laboratories to achieve a better answer to clinical needs with specific local constraints. The results from several CNRHP studies are presented: traceability to International System of Units, inter-laboratories comparability, POCT vs central labs comparisons with POCT CO-oximeter or photometer, integration of transcutaneous bilirubinometer. We propose, based on an analysis of devices advantages and issues, guidelines to help labs either to improve neonates monitoring in their local context; we distinguished the choices inside laboratory for a better harmonization of results compared to published thresholds and outside lab contexts, to organize a coordinated chain with POCT devices, with capillary and/or transcutaneous approaches.","PeriodicalId":7892,"journal":{"name":"Annales de biologie clinique","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10627235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cup-like blasts from different lineage: two clinical cases 来自不同血统的杯状胚:两例临床病例

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2022-11-01 DOI: 10.1684/abc.2022.1773

Jingnan Zhu, Fuping Shen, Sujie Zheng, Jiwei Zhao, Jinlin Liu

引用次数: 0

G6PD: a homozygous deficiency revealed by macrocytosis after acute alcoholism G6PD:急性酒精中毒后巨细胞增多症显示的纯合子缺陷

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2022-11-01 DOI: 10.1684/abc.2022.1767

Maïssa Souissi, Antoine Morel-Cahoreau, Sylvie Daliphard, Agnès Lahary, Victor Bobée

引用次数: 0

Neurofilaments: a key new biomarker for clinicians. Part 1: Importance of neurofilaments in the management of neurodegenerative diseases 神经丝:临床医生重要的新生物标志物。第1部分:神经丝在神经退行性疾病治疗中的重要性

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2022-09-01 DOI: 10.1684/abc.2022.1757

Constance Delaby, Olivier Bousiges, Damien Bouvier, Catherine Fillée, Anthony Fourier, Étienne Mondésert, Nicolas Nezry, Souheil Omar, Isabelle Quadrio, Benoit Rucheton, Susanna Schraen-Maschke, Vincent van Pesch, Stéphanie Vicca, Sylvain Lehmann, Aurélie Bedel

{"title":"Neurofilaments: a key new biomarker for clinicians. Part 1: Importance of neurofilaments in the management of neurodegenerative diseases","authors":"Constance Delaby, Olivier Bousiges, Damien Bouvier, Catherine Fillée, Anthony Fourier, Étienne Mondésert, Nicolas Nezry, Souheil Omar, Isabelle Quadrio, Benoit Rucheton, Susanna Schraen-Maschke, Vincent van Pesch, Stéphanie Vicca, Sylvain Lehmann, Aurélie Bedel","doi":"10.1684/abc.2022.1757","DOIUrl":"https://doi.org/10.1684/abc.2022.1757","url":null,"abstract":"Neurological biomarkers are of great use for clinicians, as they can be used for numerous purposes: guiding clinical diagnosis, estimating prognosis, assessing disease stage and monitoring progression or response to treatment. This field of neurology has evolved considerably in recent years due to analytical improvements in assay methods, now allowing the detection of biomarkers not only in cerebrospinal fluid (CSF) but also in blood. This progress greatly facilitates the repeated quantification of biomarkers, the collection of blood being much less invasive than that of CSF. Among the various informative biomarkers of neurological disorders, neurofilaments light chains (NfL) have proven to be particularly attractive in many contexts, in particular for the diagnosis and prognosis of neurodegenerative diseases (which this review will present), but also in other contexts of neurological disorders (which will be detailed in part 2). We further address the added value of NfL compared to other biomarkers commonly used to monitor the diseases described in this review.","PeriodicalId":7892,"journal":{"name":"Annales de biologie clinique","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40456896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of vascular endothelial growth factor (VEGF) insertion/deletion gene polymorphism and environmental risk factors in sample of Algerian population with neovascular age-related macular degeneration (nAMD) 阿尔及利亚新生血管性年龄相关性黄斑变性(nAMD)患者血管内皮生长因子(VEGF)插入/缺失基因多态性及环境危险因素分析

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2022-09-01 DOI: 10.1684/abc.2022.1762

Ghania Abid, Ahlem Messal, Mohammed Harmel, Nawel Adda Neggaz, Aicha Idder, Meriem Abdi, Djabaria Naima Meroufel, Mostefa Fodil, Faouzia Zemani-Fodil

{"title":"Analysis of vascular endothelial growth factor (VEGF) insertion/deletion gene polymorphism and environmental risk factors in sample of Algerian population with neovascular age-related macular degeneration (nAMD)","authors":"Ghania Abid, Ahlem Messal, Mohammed Harmel, Nawel Adda Neggaz, Aicha Idder, Meriem Abdi, Djabaria Naima Meroufel, Mostefa Fodil, Faouzia Zemani-Fodil","doi":"10.1684/abc.2022.1762","DOIUrl":"https://doi.org/10.1684/abc.2022.1762","url":null,"abstract":"Background: Increasing evidence shows that genetic and environmental factors can influence neovascular age-related macular degeneration (nAMD) risk. The aim of this study was first to analyse the association of insertion/deletion polymorphism in VEGF gene and environmental factors with the risk of nAMD, and then to investigate whether these factors have an impact on the age of onset of nAMD in a sample of the Algerian population.Methods: Seventy two patients with nAMD and one hundred twenty-four controls were recruited; standardized questionnaire was used to collect information regarding underlying systemic diseases and important environmental factors. Genotyping of VEGF (I/D) SNP was conducted using PCR-based assay approach, and statistical analyses were conducted using IBM SPSS statistics 21.Results: A significant association was reported of age (p < 0.05), smoking (p = 0.02), alcohol (p < 0.01), hypertension (p = 0.04), hyperlipidaemia (p = 0.008) and thyroid disease (p = 0.03) with nAMD. Also, Thyroid disease may have a role in accelerating the development of nAMD in an earlier age in our sample (p < 0.001). No association was found between the VEGF – 2549 I/D genotype and the presence of nAMD (p = 0.27), neither with the age of onset of nAMD (p = 0.21).Conclusion: Our results suggest that age, smoking, alcohol, hypertension, hyperlipidaemia and thyroid diseases are possible risk factors that could increase the risk of nAMD in a sample of Algerian population. In addition, VEGF – 2549 I/D might not be associated with the risk of nAMD development. Finally, thyroid disease may accelerate the development of nAMD in an earlier age.","PeriodicalId":7892,"journal":{"name":"Annales de biologie clinique","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40456022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disappearance of anti-thyroglobulin antibodies from the cerebrospinal fluid in parallel with neurological improvement during treatment for Hashimoto's encephalopathy 桥本脑病治疗期间脑脊液中抗甲状腺球蛋白抗体的消失与神经系统改善并行

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2022-09-01 DOI: 10.1684/abc.2022.1759

Maïwen Petithomme-Nanrocki, Aurélie Brunet, Kévin Didier, Maxime Hentzien, Thierry Tabary, Anne Doe de Maindreville, Firouzé Bani-Sadr

引用次数: 0

Primary plasma cell leukemia: what role does flow cytometry play? 原发性浆细胞白血病:流式细胞术起什么作用?

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2022-09-01 DOI: 10.1684/abc.2022.1751

Nour Louati, Yousra Fakhfakh, Mourad Chaari, Taycir Rekik, Olfa Kassar, Moez Elloumi, Hela Mnif

引用次数: 0

Self-portrait of a researcher belonging to UMR 1248 Inserm UMR 1248 Inserm研究员自画像

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2022-09-01 DOI: 10.1684/abc.2022.1756

Jean-Baptiste Woillard

引用次数: 0