桥本脑病治疗期间脑脊液中抗甲状腺球蛋白抗体的消失与神经系统改善并行

IF 0.4 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Annales de biologie clinique Pub Date : 2022-09-01 DOI:10.1684/abc.2022.1759

Maïwen Petithomme-Nanrocki, Aurélie Brunet, Kévin Didier, Maxime Hentzien, Thierry Tabary, Anne Doe de Maindreville, Firouzé Bani-Sadr

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引用次数: 0

摘要

在62-75%的桥本脑病病例中，脑脊液中甲状腺抗体异常升高。然而，脑脊液甲状腺抗体水平与治疗反应之间的关系尚未得到充分评价。我们报告一例68岁的桥本脑病患者，其良好的临床结果与脑脊液中抗甲状腺抗体的消失和血清甲状腺抗体的下降有关。

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Disappearance of anti-thyroglobulin antibodies from the cerebrospinal fluid in parallel with neurological improvement during treatment for Hashimoto's encephalopathy

Abnormal elevation of thyroid antibodies in the CSF is observed in 62-75% of Hashimoto's encephalopathy cases. However, the relationship between CSF thyroid antibody levels and response to therapy has been poorly evaluated. We report the case of a 68-year-old man with Hashimoto's encephalopathy, in whom there was a relation between the favorable clinical outcome and the disappearance of antithyroid antibodies from the CSF and a decrease in serum thyroid antibodies.

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来源期刊

Annales de biologie clinique 医学-医学：研究与实验

CiteScore

0.80

自引率

20.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Multidisciplinary information with direct relevance to everyday practice Annales de Biologie Clinique, the official journal of the French Society of Clinical Biology (SFBC), supports biologists in areas including continuing education, laboratory accreditation and technique validation. With original articles, abstracts and accounts of everyday practice, the journal provides details of advances in knowledge, techniques and equipment, as well as a forum for discussion open to the entire community.