Annales de biologie clinique最新文献_第3页

Gigantic Flaming Cells in an IgA-MGUS patient. IgA-MGUS患者体内巨大的燃烧细胞。

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2023-05-16 DOI: 10.1684/abc.2023.1795

Wei Pan, Yuguo Zhou, Jiwei Zhao, Jinlin Liu

引用次数: 0

[Monitoring of heparinization in cardiac surgery with ACT: accreditation of the point-of-care test in the Bordeaux University Hospital Centre]. [用ACT监测心脏手术中的肝素化:波尔多大学医院中心即时护理测试的认可]。

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2023-05-16 DOI: 10.1684/abc.2023.1794

Valentin Landrieu, Marie Christine Beauvieux, Thomas Vidal, Christine Mouton, Gladys Castaing-Mouhica, Laurent Dusseau, Eugen Stanciu, Julien Domingorena, David Roux, Julien Catel, Valerie Moreno, Nathalie Berthon, Delphine Bachellerie, Sandy Poisvert, Céline Delassasseigne

{"title":"[Monitoring of heparinization in cardiac surgery with ACT: accreditation of the point-of-care test in the Bordeaux University Hospital Centre].","authors":"Valentin Landrieu, Marie Christine Beauvieux, Thomas Vidal, Christine Mouton, Gladys Castaing-Mouhica, Laurent Dusseau, Eugen Stanciu, Julien Domingorena, David Roux, Julien Catel, Valerie Moreno, Nathalie Berthon, Delphine Bachellerie, Sandy Poisvert, Céline Delassasseigne","doi":"10.1684/abc.2023.1794","DOIUrl":"https://doi.org/10.1684/abc.2023.1794","url":null,"abstract":"ACT (Activated Clotting Time) is a point of care test (POCT) on whole blood, used to monitor the heparinization of patients in the operating room in cardiac surgery (ExtraCorporeal Circulation ECC) and in interventional cardiology (TAVI, AF ablation). The ACT is concerned both by the ISO 22 870 standard and French regulations regarding POCT. We performed an important work at the Bordeaux CHU on its accreditation, by rationalizing and making the park uniform (11 HemochronTM Signature Elite), standardizing the training and the habilitation of operators in medical units, introducing periodic quality controls, centralizing in the laboratory the management of the devices and reagents and by connecting it to the laboratory's computer system (Middleware, SIL et expert softwares). One year after, we have some positive feedbacks with only a few technical problems and with only few remarks raised during internal audits.","PeriodicalId":7892,"journal":{"name":"Annales de biologie clinique","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9485126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[AML with myelodysplasia-related changes complicating xeroderma pigmentosum]. [AML伴骨髓增生异常相关改变并发着色性干皮病]。

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2023-05-16 DOI: 10.1684/abc.2023.1799

Loubna Darfaoui, Salma Amrani Idrissi, Wafae Quiddi, Sanae Sayagh

引用次数: 0

Congenital analbuminemia associated with compound heterozygous novel nucleotide variations in a young adult with coronary thrombosis. 先天性白蛋白血症与冠状动脉血栓形成的年轻成人的复合杂合新核苷酸变异相关。

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2023-05-16 DOI: 10.1684/abc.2023.1806

Yessine Amri, Sana Aboulkacem, Rym Dabboubi, Manel Ayoub, Oussema Lamine, Mariem Othmani, Zied Aouni, Taieb Messaoud, Chakib Mazigh

{"title":"Congenital analbuminemia associated with compound heterozygous novel nucleotide variations in a young adult with coronary thrombosis.","authors":"Yessine Amri, Sana Aboulkacem, Rym Dabboubi, Manel Ayoub, Oussema Lamine, Mariem Othmani, Zied Aouni, Taieb Messaoud, Chakib Mazigh","doi":"10.1684/abc.2023.1806","DOIUrl":"https://doi.org/10.1684/abc.2023.1806","url":null,"abstract":"Congenital analbuminemia (CAA) is a very rare genetic disorder characterized by a significant reduced or even complete absence of human serum albumin. Our data describe the clinical features and laboratory results of a case confirmed by mutation analysis of the albumin gene in a 35-year-old man presenting recurrent acute coronary syndrome. To the best of our knowledge, only two cases of coronary artery disease have been reported worldwide without recurrence. Our findings contribute to shed light on the clinical characteristics and biochemical parameters of this disease and confirm that cardiovascular complications must be taken seriously in this pathology. Mutational screening disclosed two novel compound heterozygous nucleotide variations located in intron 12 and in 3'UTR. The prediction of the functional and structural impact of the reported variations using different bioinformatics tools demonstrates that these genetics variations affect RNA transcription and mRNA folding.","PeriodicalId":7892,"journal":{"name":"Annales de biologie clinique","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9468132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Democratization of Education: Adaptive Learning Courses in Laboratory Medicine Are Now Available without A Subscription Fee!] 教育民主化:检验医学的适应性学习课程现在可以免费使用!］

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2023-05-16 DOI: 10.1684/abc.2023.1792

Nader Rifai

引用次数: 0

[Real-life evaluation of hypersensitive I-troponin on a point-of care analyser in an emergency unit]. [在急诊病房的即时护理分析仪上对超敏感肌钙蛋白的真实评估]。

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2023-05-16 DOI: 10.1684/abc.2023.1804

Léo Mottin, Iliasse Idrissi Kassimy, Hélène Girot, Romain Leguillon, Luc Marie Joly, Valery Brunel

{"title":"[Real-life evaluation of hypersensitive I-troponin on a point-of care analyser in an emergency unit].","authors":"Léo Mottin, Iliasse Idrissi Kassimy, Hélène Girot, Romain Leguillon, Luc Marie Joly, Valery Brunel","doi":"10.1684/abc.2023.1804","DOIUrl":"https://doi.org/10.1684/abc.2023.1804","url":null,"abstract":"European Society of Cardiology (ESC) guidelines allow to perform rapid rule-in and rule-out algorithm with rapid troponin kinetics for the management of suspected Non ST-elevation acute coronary syndrome. These recommendations allow the use of point-of-care testing (POCT) systems provided that they have sufficient analytical performance. The aim of our study was to evaluate in real life the feasibility and performance of using a high sensitivity cardiac troponin I POCT system assay (hs-cTnI, Atellica® VTLi, Siemens) compared to high sensitivity cardiac troponin T values (hs-cTnT, e602®, Roche) obtained for patients admitted to emergency department. Analytical verification showed a coefficient of variation below 10% for hs-cTnI. Comparison of both troponins was moderate (r = 0.7). The study included 117 patients with a median age of 65 years, 30% had renal failure and 36% presented with chest pain. In this study, the hs-cTnT value was, more often, higher than the 99th percentile than the hs-cTnl value, even for an age-adjusted 99th percentile hs-cTnT value. The concordance of the results was moderate (Cohen's Kappa: 0.54), age remaining the most important explanatory value of discordance. Only hs-cTnT had a predictive value for hospitalization. We did not observe any interpretation discrepancies for patients who had troponin kinetics. This study confirms the feasibility of using a POCT analyzer in the emergency department, provided that it performs high sensitivity troponin. However, some data are missing to be able to use it in the framework of rapid algorithm. Finally, the implementation of POCT requires collaboration between biologists and emergency physicians in terms of organization and interpretation of values, for the overall benefit of the patient.","PeriodicalId":7892,"journal":{"name":"Annales de biologie clinique","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9483418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Blastoid variant mantle cell lymphoma with aberrant expression of CD10. CD10异常表达的胚样变套细胞淋巴瘤。

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2023-05-16 DOI: 10.1684/abc.2023.1796

Benjamin Podvin, Jean-Baptiste Bossard, Christine Pucalowski, Geoffrey Bouchez

引用次数: 0

[Contribution of hematology analyzers (Sysmex XN-Series) in the rapid diagnosis of malaria: case reports]. [Sysmex xn系列血液分析仪在疟疾快速诊断中的贡献:病例报告]。

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2023-03-21 DOI: 10.1684/abc.2023.1791

Pauline Pitti, Françoise Tassin, Aurore Keutgens

{"title":"[Contribution of hematology analyzers (Sysmex XN-Series) in the rapid diagnosis of malaria: case reports].","authors":"Pauline Pitti, Françoise Tassin, Aurore Keutgens","doi":"10.1684/abc.2023.1791","DOIUrl":"https://doi.org/10.1684/abc.2023.1791","url":null,"abstract":"Malaria is a potentially severe disease, particularly in Africa. In Europe, the majority of malaria cases come from travelers returning from endemic areas. The non-specific symptomatology may not alert the clinician if this notion of travel is not addressed. However, diagnosis and rapid initiation of treatment prevent the evolution of severe forms of the disease, especially in the case of Plasmodium falciparum infection, which can be life-threatening within 24 hours. Thin and thick blood smears microscopy is the main tools for diagnosis, but some automated hematology analyzers have demonstrated their ability to participate in early diagnosis. We describe two cases illustrating the contribution of the Sysmex XN-9100 automated system for the diagnosis of malaria. The first clinical case described a young man infected with numerous Plasmodium falciparum gametocytes. WNR (white blood cell count) and WDF (white blood cell differenciation) scattergrams showed an additional population, corresponding to gametocytes. The second case focused on a man with neuromalaria and high Plasmodium falciparum parasitaemia. Parasitized red blood cells form an inconspicuous double population on the reticulocyte scattergram, located at the discrimination limit between mature red blood cells and reticulocytes. Scattergram abnormalities, which can be visualized in a few minutes, offer an anticipation of the diagnosis of malaria in comparison to thin and thick smears microscopy, that requiring considerable time and expertise.","PeriodicalId":7892,"journal":{"name":"Annales de biologie clinique","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9482337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Help sheets for ordonnance in biochemistry: proposal]. [生物化学弹药说明书:提案]。

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2023-03-15 DOI: 10.1684/abc.2023.1783

Gaspard Beaune, Charlotte Oris, Hana Talabani Boizot, Magali Annette-Reisch, Matthieu Pecquet, François Schmitt

引用次数: 0

[Triose phosphate isomerase deficiency: a rare erythrocyte enzymopathy with a poor prognosis]. 磷酸三糖异构酶缺乏症:一种罕见的红细胞酶病，预后不良。

IF 0.5 4区医学

Annales de biologie clinique Pub Date : 2023-03-15 DOI: 10.1684/abc.2023.1789

Mélissa Julien, Calina Todosi, Fanny Fouyssac, Jean-François Lesesve, Delphine Gérard, Julien Perrin

引用次数: 0