Animal Science Journal最新文献_第7页

Effect of Supplemented Spent Mushroom Substrate (Pleurotus ostreatus) on Growth Performance, Nutrient Digestibility, Nitrogen Balance, and Blood Metabolites of Goats. 添加废菌底物对山羊生长性能、营养物质消化率、氮平衡和血液代谢物的影响

IF 1.6 3区农林科学

Animal Science Journal Pub Date : 2026-01-01 DOI: 10.1111/asj.70167

Jane Camille A Crisostomo, Momona Chujo, Melchor P Pascua, Neal A Del Rosario, Jamal James D Manlapig, Edgar A Orden, Hiroki Matsui, Tomomi Ban-Tokuda

{"title":"Effect of Supplemented Spent Mushroom Substrate (Pleurotus ostreatus) on Growth Performance, Nutrient Digestibility, Nitrogen Balance, and Blood Metabolites of Goats.","authors":"Jane Camille A Crisostomo, Momona Chujo, Melchor P Pascua, Neal A Del Rosario, Jamal James D Manlapig, Edgar A Orden, Hiroki Matsui, Tomomi Ban-Tokuda","doi":"10.1111/asj.70167","DOIUrl":"10.1111/asj.70167","url":null,"abstract":"This study evaluated the effects of Pleurotus ostreatus spent mushroom substrate (SMS), supplemented with 4% urea and 18% molasses, as a partial replacement for Napier grass. Four dietary treatments were formulated with 70% roughage (Napier grass) and 30% concentrate, replacing Napier grass with SMS at 0%, 20%, 35%, or 50% inclusion levels. A 120-day feeding including a 7-day digestibility trial was conducted using 20 3-month-old upgraded Anglo-Nubian goats (7.81 ± 0.39 kg). Goats fed diets containing 20%-35% SMS maintained average daily gain and feed conversion efficiency comparable to the control group, while 50% SMS inclusion significantly reduced both parameters (p < 0.05). Dry matter intake and digestibility of dry matter, organic matter, and crude protein decreased with increasing SMS levels, whereas ether extract digestibility improved. Nitrogen absorption was significantly reduced at higher inclusion levels (p < 0.05). Ruminal pH increased linearly, accompanied by a decrease in total short-chain fatty acids, acetate, and propionate concentrations. Serum glucose, total cholesterol, triglycerides, and creatinine remained within normal ranges, although blood urea nitrogen increased with higher SMS inclusion. Overall, moderate SMS inclusion (up to 35%) supported goat performance and nutrient utilization, while higher levels may limit digestibility and fermentation, indicating the need for additional processing to enhance its feeding value.","PeriodicalId":7890,"journal":{"name":"Animal Science Journal","volume":"97 1","pages":"e70167"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12983990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147442142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Field Validation of a Visible-Light Camera-Based Calving Detection System in Commercial Beef Cattle Farms. 基于可见光相机的产犊检测系统在商业肉牛养殖场的现场验证。

IF 1.6 3区农林科学

Animal Science Journal Pub Date : 2026-01-01 DOI: 10.1111/asj.70218

Hisashi Nabenishi, Miku Odaka, Miyu Mochizuki, Nagisa Taki, Shoji Nishibayashi, Tomoyuki Ishii

{"title":"Field Validation of a Visible-Light Camera-Based Calving Detection System in Commercial Beef Cattle Farms.","authors":"Hisashi Nabenishi, Miku Odaka, Miyu Mochizuki, Nagisa Taki, Shoji Nishibayashi, Tomoyuki Ishii","doi":"10.1111/asj.70218","DOIUrl":"10.1111/asj.70218","url":null,"abstract":"Efficient monitoring of cows during the periparturient period is essential for reducing calving-related losses and labor demands. This study evaluated a camera-based calving detection system using visible-light images under commercial farm conditions. A total of 61 cameras were installed on 31 beef cattle farms, and data from 357 calving events were analyzed. Behavioral parameters, including movement distance, posture changes and tail-raising behavior, were analyzed using an artificial intelligence-based system. An alert was generated when the estimated calving probability exceeded 70%. Using a predefined criterion of at least one alert within 24 h before calving, the system successfully detected 336 of 357 calving events, resulting in a sensitivity of 94.1%. A total of 448 successful alerts and 191 early alerts were recorded, resulting in a positive predictive value of 70.1%. The mean interval between the first alert and calving was 192 ± 9 min, and the median interval was 142 min (interquartile range: 75-250 min). Alert frequency increased significantly as calving approached (p < 0.05). These results indicate that visible camera-based monitoring can effectively detect calving events and may provide a practical, non-invasive tool for improving calving management in beef cattle.","PeriodicalId":7890,"journal":{"name":"Animal Science Journal","volume":"97 1","pages":"e70218"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13349422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148395631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pyruvate Dehydrogenase Kinase 4 Gene Expression Is Highly Responsive to Hypertonic Saline Administration in Chicks. 丙酮酸脱氢酶激酶4基因表达对高渗盐水的高度反应。

IF 1.6 3区农林科学

Animal Science Journal Pub Date : 2026-01-01 DOI: 10.1111/asj.70196

Nnamdi Godswill Dialoke, Kaoruko Murata, Yumi Sakanashi, Junya Takegaki, Takaoki Saneyasu, Kazuhisa Honda

{"title":"Pyruvate Dehydrogenase Kinase 4 Gene Expression Is Highly Responsive to Hypertonic Saline Administration in Chicks.","authors":"Nnamdi Godswill Dialoke, Kaoruko Murata, Yumi Sakanashi, Junya Takegaki, Takaoki Saneyasu, Kazuhisa Honda","doi":"10.1111/asj.70196","DOIUrl":"10.1111/asj.70196","url":null,"abstract":"Proteins and lipids are used as sources of endogenous water under dehydrated conditions in birds. However, it is unclear whether protein and fat are catabolized by dehydration in chickens. Elevated plasma osmolality is one of the responses to dehydration. The present study attempted to clarify the dose-dependent effects of hypertonic saline on plasma components and protein and lipid metabolism-related gene expression in the breast muscle and adipose tissue of chicks. The intraperitoneal administration of 1.2 M NaCl (5 mL/kg body weight) to 21-day-old chicks significantly increased the plasma concentration of nonesterified fatty acids, pyruvate dehydrogenase kinase 4 (PDK4) mRNA levels in breast muscle and adipose tissue, and atrogin-1 mRNA levels in breast muscle after 60 min. In the case of 0.6 M NaCl, a significant effect was only observed in PDK4 mRNA levels in both tissues. PDK4 functions as the metabolic switch from glucose to fatty acid utilization. Thus, hypertonic saline-induced changes in gene expression profiles suggest a potential shift toward lipid utilization in the peripheral tissues of chicks.","PeriodicalId":7890,"journal":{"name":"Animal Science Journal","volume":"97 1","pages":"e70196"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148040744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enriching Activated Charcoal With Aged Palm Sap Improves Laying Hen Performance, Egg Quality, and Reproductive Function. 用陈年棕榈液富集活性炭可提高蛋鸡生产性能、蛋品质和生殖功能。

IF 1.6 3区农林科学

Animal Science Journal Pub Date : 2026-01-01 DOI: 10.1111/asj.70250

Albert Uzochukwu Chinenye Ohanaka, Judith Nkechinyere Ohanaka, Ifeanyi Princewill Ogbuewu, Ifeanyi Charles Okoli

{"title":"Enriching Activated Charcoal With Aged Palm Sap Improves Laying Hen Performance, Egg Quality, and Reproductive Function.","authors":"Albert Uzochukwu Chinenye Ohanaka, Judith Nkechinyere Ohanaka, Ifeanyi Princewill Ogbuewu, Ifeanyi Charles Okoli","doi":"10.1111/asj.70250","DOIUrl":"https://doi.org/10.1111/asj.70250","url":null,"abstract":"This study evaluated the effects of activated charcoal (AC) and aged palm sap-enriched AC (AC + APS) on laying performance, egg quality, reproductive physiology, hematology, and serum biochemistry of laying hens alongside physicochemical characterization of the additives. Two hundred and forty Isa Brown hens were assigned to five dietary treatments: control, 0.5% AC, 1.0% AC, 0.5% AC + APS, and 1.0% AC + APS during a 12-week feeding trial. High-performance liquid chromatography identified glucose, fructose, lactic, pyruvic, and acetic acids as major APS metabolites, while Fourier transform infrared spectroscopy confirmed APS-mediated surface modification of AC through the emergence and intensification of oxygenated functional groups. Dietary supplementation significantly improved hen-day egg production, egg mass, feed conversion ratio, eggshell thickness, ovarian development, follicular recruitment, and progesterone concentration (p < 0.05). AC + APS-fed hens exhibited greater ovarian and follicular weights and more large yellow follicles than AC-only groups, indicating enhanced folliculogenesis. While increasing AC inclusion from 0.5% to 1.0% improved several productive indices, comparable responses between 0.5% and 1.0% AC + APS suggested enhanced biological efficiency following APS functionalization. Hematological and biochemical responses further supported enhanced metabolic adaptation and reproductive allocation. Overall, APS enrichment transformed AC into a multifunctional bioactive feed additive for sustainable laying hen production and biomass valorization.","PeriodicalId":7890,"journal":{"name":"Animal Science Journal","volume":"97 1","pages":"e70250"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Meat Hydrolysates Inhibited Dipeptidyl Peptidase-IV Activity In Vitro Model. 肉水解物抑制二肽基肽酶- iv体外模型活性。

IF 1.6 3区农林科学

Animal Science Journal Pub Date : 2026-01-01 DOI: 10.1111/asj.70202

Shinichi Takenoyama, Kumiko Kawakita, Toyoo Nakamura, Michio Muguruma

{"title":"Meat Hydrolysates Inhibited Dipeptidyl Peptidase-IV Activity In Vitro Model.","authors":"Shinichi Takenoyama, Kumiko Kawakita, Toyoo Nakamura, Michio Muguruma","doi":"10.1111/asj.70202","DOIUrl":"10.1111/asj.70202","url":null,"abstract":"The inhibitory activity of dipeptidyl peptidase-IV (DPP-IV), an enzyme involved in the suppression of blood glucose elevation, was evaluated using various meat hydrolysates and chicken meat hydrolysate pellet (CMP). Hydrolysates prepared from beef, pork, and chicken by digestion with the food-grade enzyme Protamex for 90 min exhibited approximately 70% DPP-IV inhibitory activity. The IC50 values for DPP-IV inhibition were 3.2, 3.4, and 3.9 mg/mL for beef, pork, and chicken hydrolysates, respectively. Solutions containing chicken hydrolysate tablets demonstrated concentration-dependent inhibitory activity, with a fivefold diluted solution still showing high inhibition of over 80%. The IC50 value of CMP was 3.3 mg/mL, indicating that inhibitory activity was retained following hydrolysis, spray-drying, and tableting. The fraction with a molecular weight ≤ 3000 Da, which accounts for 65% of the chicken meat hydrolysate tablets, was enriched in peptides with potent blood glucose-regulating and blood pressure-lowering activities. This study demonstrated that food-derived meat hydrolysates possess DPP-IV inhibitory activity associated with blood glucose regulation. Chicken meat hydrolysate products, developed as functional peptide powders and tablets with adjusted protein content, exhibit high digestibility and absorption, as well as antioxidant, anti-fatigue, blood pressure-lowering, and blood glucose-regulating effects.","PeriodicalId":7890,"journal":{"name":"Animal Science Journal","volume":"97 1","pages":"e70202"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148300703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Novel Genetic Management Procedure for Preserving the Genetic Composition of Captive Founders. 一种保存圈养创始人遗传组成的新遗传管理程序。

IF 1.6 3区农林科学

Animal Science Journal Pub Date : 2026-01-01 DOI: 10.1111/asj.70210

Takeshi Honda, Kazuaki Naito, Kenji Oyama

{"title":"A Novel Genetic Management Procedure for Preserving the Genetic Composition of Captive Founders.","authors":"Takeshi Honda, Kazuaki Naito, Kenji Oyama","doi":"10.1111/asj.70210","DOIUrl":"10.1111/asj.70210","url":null,"abstract":"Maintaining the genetic composition of the captive founders is one of the essential tasks in ex situ captive breeding programs. Although minimization of the average coancestry of the current animals is the most widely accepted genetic management procedure when relationships among the captive founders are unknown (MC method), it has become possible to estimate the relatedness of the founders owing to the development of genotyping techniques and population genetics theory. In this study, we propose a novel genetic management procedure for preserving the genetic composition of captive founders that is applicable when the relatedness among them can be accurately estimated. The expression of genetic drift derived in this study suggested that Nei's minimum distance between the captive founders and the current animals is a key indicator for the novel genetic management. Computer simulation assuming unspecified organism indicated that the novel management preserves the original allele frequencies more effectively than the MC method, especially when the population size is contracting, and keeps the expected heterozygosity at a higher level, especially when the population size is expanding. We also exemplify the practical application of the proposed method by computer simulation using demographic data of the Oriental stork raised in Japan.","PeriodicalId":7890,"journal":{"name":"Animal Science Journal","volume":"97 1","pages":"e70210"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148306530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Low-Protein Dried Distillers' Grains With Solubles in High-Concentrate Diets for Finishing Lambs. 低蛋白干酒糟与可溶性物在高精料饲粮中对育肥羔羊的影响。

IF 1.6 3区农林科学

Animal Science Journal Pub Date : 2026-01-01 DOI: 10.1111/asj.70190

Renan Marvila da Silva Santos, Alexandre Lima de Souza, Anderson de Moura Zanine, Luis Juliano Valério Geron, Daniele de Jesus Ferreira Zanine, André Gustavo Leão, Carla Heloisa Avelino Cabral, Rodrigo Junqueira Pereira, Luciano da Silva Cabral, Fagton de Mattos Negrão, Lucas Gimenes Mota

{"title":"Effects of Low-Protein Dried Distillers' Grains With Solubles in High-Concentrate Diets for Finishing Lambs.","authors":"Renan Marvila da Silva Santos, Alexandre Lima de Souza, Anderson de Moura Zanine, Luis Juliano Valério Geron, Daniele de Jesus Ferreira Zanine, André Gustavo Leão, Carla Heloisa Avelino Cabral, Rodrigo Junqueira Pereira, Luciano da Silva Cabral, Fagton de Mattos Negrão, Lucas Gimenes Mota","doi":"10.1111/asj.70190","DOIUrl":"10.1111/asj.70190","url":null,"abstract":"This study evaluated the effects of increasing inclusion levels of low-protein dried distillers' grains with solubles (DDGS) in high-concentrate diets on nutrient intake, digestibility, nitrogen balance, and ingestive behavior of finishing lambs. Four Santa Inês crossbred, uncastrated male lambs (24.8 ± 1.0 kg body weight) were assigned to four dietary treatments in a 4 × 4 Latin square design. Treatments consisted of a control diet without DDGS and diets containing 200, 400, or 600 g/kg dry matter (DM) of low-protein DDGS. DM and TDN intakes showed quadratic responses (p < 0.05) to DDGS inclusion. Neutral detergent fiber intake increased linearly, whereas NFC intake decreased linearly (p < 0.05). Inclusion of DDGS did not affect (p > 0.05) apparent digestibility of DM, CP, or EE. However, NDF digestibility increased linearly by 4.99 g/kg per unit of DDGS added. Nitrogen retention, plasma urea nitrogen, and blood glucose were not affected. Rumination time increased linearly (p < 0.05). Low-protein DDGS can be included at 600 g/kg DM in finishing lamb diets. However, including 200 or 400 g/kg DM may result in negative associative effects for some variables. Overall, low-protein DDGS remains a valuable feed ingredient for substituting ground corn and soybean meal.","PeriodicalId":7890,"journal":{"name":"Animal Science Journal","volume":"97 1","pages":"e70190"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148013120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and Validation of a 500-mL In Vitro Fermentation Bottle System for Gas Production, Methane, and Nutrient Degradability. 开发和验证一个500毫升体外发酵瓶系统的气体生产，甲烷，和营养降解。

IF 1.6 3区农林科学

Animal Science Journal Pub Date : 2026-01-01 DOI: 10.1111/asj.70193

Jane Camille A Crisostomo, Yuna Sakata, Takumi Sekoguchi, Toshiki Umeki, Yasunari Yamamoto, Tomomi Ban-Tokuda, Makoto Kondo, Hiroki Matsui

{"title":"Development and Validation of a 500-mL In Vitro Fermentation Bottle System for Gas Production, Methane, and Nutrient Degradability.","authors":"Jane Camille A Crisostomo, Yuna Sakata, Takumi Sekoguchi, Toshiki Umeki, Yasunari Yamamoto, Tomomi Ban-Tokuda, Makoto Kondo, Hiroki Matsui","doi":"10.1111/asj.70193","DOIUrl":"10.1111/asj.70193","url":null,"abstract":"A laboratory-scale in vitro fermentation system using modified 500-mL bottles was developed and validated for the measurement of gas, methane production, and nutrient degradability of ruminant feed substrates. The system was designed to accommodate a larger substrate volume than conventional small-volume in vitro systems while maintaining anaerobic conditions for gas sampling. Validation of the system was conducted using diets formulated at different roughage-to-concentrate ratios (80:20, 50:50, and 20:80), incubated with rumen fluid collected from Japanese Black cattle for 24 h at 39°C. In vitro dry matter and organic matter degradability and total gas production increased with a higher proportion of concentrate (p = 0.0002; p = 0.0002; and p < 0.0001, respectively), whereas methane production expressed per unit of degraded dry matter (CH4/DMD) and pH after 24 h of incubation decreased (p = 0.0008 and p = 0.0118, respectively). The crude protein, neutral detergent fiber, and acid detergent fiber degradability and the amount of short-chain fatty acid produced were not affected by the dietary treatment (p > 0.05). The modified 500-mL bottle system enabled simultaneous assessment of gas and methane production and multiple degradability parameters within a single incubation, supporting its use in laboratory-scale in vitro rumen fermentation studies.","PeriodicalId":7890,"journal":{"name":"Animal Science Journal","volume":"97 1","pages":"e70193"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148040796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estimation of Heritabilities for Meat Quality Traits Across Japanese Duroc Populations. 日本杜洛克群体肉质性状遗传力的估计。

IF 1.6 3区农林科学

Animal Science Journal Pub Date : 2026-01-01 DOI: 10.1111/asj.70231

Aisaku Arakawa, Motohide Nishio, Toshihiro Okamura, Masaaki Taniguchi, Chika Ohnishi, Kouen Kadowaki, Akira Yobuko, Tomohito Itoh, Nodoka Matsunaga, Fumika Homma, Kazunori Matsumoto, Takatoshi Kojima, Kazuo Ishii

{"title":"Estimation of Heritabilities for Meat Quality Traits Across Japanese Duroc Populations.","authors":"Aisaku Arakawa, Motohide Nishio, Toshihiro Okamura, Masaaki Taniguchi, Chika Ohnishi, Kouen Kadowaki, Akira Yobuko, Tomohito Itoh, Nodoka Matsunaga, Fumika Homma, Kazunori Matsumoto, Takatoshi Kojima, Kazuo Ishii","doi":"10.1111/asj.70231","DOIUrl":"10.1111/asj.70231","url":null,"abstract":"The genetic components for meat quality traits, such as physical characteristics and chemical traits, remain unclear. This study focused on estimating heritability for 44 meat quality traits, including chemical traits, such as general composition (moisture, crude fat, and crude protein), and fatty acid composition in Japanese Duroc populations. We collected samples from 312 commercial Duroc pigs at three different stations. Fatty acid compositions were measured in the loin eye (longissimus thoracis) muscle and subcutaneous fat. Estimates of heritability for general composition traits ranged from 0.11 to 0.87. In addition, the heritability estimates related to pork tenderness were assumed to be moderately heritable. The heritability estimates for fatty acid composition in both tissues ranged from 0.00 to 1.00. The weighted heritability estimates obtained by meta-analysis ranged from 0.01 to 0.61 for general composition traits and 0.25 to 1.00 for fatty acid composition in both tissues. Our findings suggest that most of meat quality traits in these Japanese Duroc populations are influenced by substantial genomic factors, and the influence of genetic factors on these traits could be shared across breeds. These results provide valuable genetic information needed to design a breeding program aimed at improving the pork quality of Duroc breeds.","PeriodicalId":7890,"journal":{"name":"Animal Science Journal","volume":"97 1","pages":"e70231"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13454515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148700619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peroxisome Proliferator-Activated Receptor Delta Regulates Myogenic Differentiation via Lipid Droplet-Associated Metabolic Remodeling and p38 MAPK Signaling. 过氧化物酶体增殖物激活受体通过脂滴相关代谢重塑和p38 MAPK信号传导调节肌源性分化。

IF 1.6 3区农林科学

Animal Science Journal Pub Date : 2026-01-01 DOI: 10.1111/asj.70221

Rumana Mahzabin, Md Rezwanul Habib, Yukako Tokutake, Shinichi Yonekura

{"title":"Peroxisome Proliferator-Activated Receptor Delta Regulates Myogenic Differentiation via Lipid Droplet-Associated Metabolic Remodeling and p38 MAPK Signaling.","authors":"Rumana Mahzabin, Md Rezwanul Habib, Yukako Tokutake, Shinichi Yonekura","doi":"10.1111/asj.70221","DOIUrl":"10.1111/asj.70221","url":null,"abstract":"Skeletal muscle development and metabolic regulation are critical for livestock productivity and meat quality. This study investigated the role of peroxisome proliferator-activated receptor delta (PPARδ) in myogenic differentiation and lipid droplet (LD) formation, focusing in particular on p38 mitogen-activated protein kinase (MAPK) signaling. C2C12 myoblasts were induced to differentiate and treated with the PPARδ agonist GW501516 or antagonist GSK3787. Myogenic differentiation was then assessed via myosin heavy chain immunostaining and calculation of the fusion index and myotube area. LD formation was evaluated by BODIPY staining and analysis of Plin2 expression. Activation of p38 MAPK was analyzed via Western blotting, and its role was examined using the inhibitor SB203580. Activation of PPARδ significantly enhanced myogenic differentiation, whereas its inhibition suppressed this process. PPARδ activation also promoted LD formation and upregulated Plin2 expression during early differentiation. In addition, GW501516 increased p38 MAPK phosphorylation. Inhibition of p38 MAPK markedly attenuated both LD formation and myogenic differentiation induced by PPARδ activation. These findings demonstrate that PPARδ promotes myogenic differentiation through coordinated lipid metabolic remodeling and p38 MAPK signaling, highlighting an association between metabolic regulation and muscle differentiation. This pathway may represent a potential target for improving muscle development and meat quality in livestock.","PeriodicalId":7890,"journal":{"name":"Animal Science Journal","volume":"97 1","pages":"e70221"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13374592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148468511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0