Anesthesiology and Pain Medicine最新文献

{"title":"Multimodal Regional Anesthesia Combining Spinal and Erector Spinae Plane Block for Spine Surgery in a High-Risk Patient with Systemic Sclerosis: A Case Report.","authors":"Alireza Shakeri, Jina Behjati","doi":"10.5812/aapm-160051","DOIUrl":"10.5812/aapm-160051","url":null,"abstract":"<p><strong>Introduction: </strong>The erector spinae plane block (ESPB) is a novel regional anesthesia technique that is increasingly incorporated into multimodal analgesia as part of enhanced recovery after surgery (ERAS) pathways in various surgical procedures, including spine surgery.</p><p><strong>Case presentation: </strong>We report the successful use of spinal anesthesia (SA), ESPB, and magnesium sulfate in a high-risk patient with systemic sclerosis and pulmonary fibrosis undergoing laminectomy. A multimodal approach was selected due to the patient's underlying condition. This strategy minimized respiratory complications associated with general anesthesia while providing effective surgical anesthesia and postoperative pain control without opioid-related complications.</p><p><strong>Conclusions: </strong>Our case highlights the utility of ESPB, not only for postoperative pain management but also as a valuable adjunct to primary anesthesia, especially in high-risk patients.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"15 2","pages":"e160051"},"PeriodicalIF":0.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding on \"Analyzing Patterns in Anesthesiology Residents' Exam Performance Using Data Mining Techniques\".","authors":"Seyed Mohammad Seyed Alshohadaei, Fereshteh Baghizadeh","doi":"10.5812/aapm-159478","DOIUrl":"10.5812/aapm-159478","url":null,"abstract":"","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"15 2","pages":"e159478"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Magnitude of Anesthesiology Residents Burnout at Shahid Beheshti University of Medical Sciences: A Cross-Sectional Study.","authors":"Maedeh Karimian, Ali Dabbagh, Parisa Sezari, Kamal Fani, Marzieh Shahrabi, Alireza Shakeri","doi":"10.5812/aapm-159987","DOIUrl":"10.5812/aapm-159987","url":null,"abstract":"<p><strong>Background: </strong>Burnout is a psychological syndrome characterized by emotional exhaustion, depersonalization, and reduced personal accomplishment, particularly prevalent among anesthesiology residents due to their demanding work environment.</p><p><strong>Objectives: </strong>This study aimed to assess the prevalence of burnout and its associations with depression, sleep quality, and quality of life among anesthesiology residents at Shahid Beheshti University of Medical Sciences.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in 2023 with 51 anesthesiology residents. Validated Persian versions of standardized tools, including the Maslach Burnout Inventory (MBI), Patient Health Questionnaire-9 (PHQ-9), Epworth Sleepiness Scale (ESS), STOP-Bang test, and World Health Organization (WHO) Quality of Life (WHOQOL-BREF) Questionnaire, were used to measure burnout, depression, sleep quality, and quality of life. Descriptive statistics and correlation analyses explored associations between these variables.</p><p><strong>Results: </strong>Burnout was highly prevalent: 41.2% of residents experienced severe emotional exhaustion, 66.7% exhibited high depersonalization, and 100% reported reduced personal accomplishment. Severe depression affected 17.65% of participants, correlating strongly with all burnout dimensions. Emotional exhaustion was significantly associated with increased daytime sleepiness (r = 0.470, P < 0.001), while burnout severity inversely impacted physical, psychological, and social quality of life. Emotional support emerged as a critical protective factor against burnout. Exploratory analyses revealed no significant gender differences in burnout, depression, or sleep quality, though small effect sizes suggested trends toward higher emotional exhaustion and depression among female residents.</p><p><strong>Conclusions: </strong>The study highlights the alarming prevalence of burnout among anesthesiology residents, driven by occupational stress, sleep disturbances, and mental health challenges. These findings align with research in other high-stress specialties, such as emergency medicine and surgery, but also underscore unique stressors faced by anesthesiology residents. Targeted interventions, such as optimizing work conditions, enhancing emotional support, and addressing mental health and sleep issues, are urgently needed. Longitudinal and comparative studies are recommended to further explore burnout progression and develop specialty-specific strategies to improve resident well-being and patient care outcomes.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"15 2","pages":"e159987"},"PeriodicalIF":0.0,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyoid Cricoid Distance-Based Method Versus Weight‑Based Method for Choosing the Appropriate Size for Classic Laryngeal Mask Airway Selection in Adults.","authors":"Dariush Abtahi, Ardeshir Tajbakhsh, Shahram Sayadi, Mohsen Shojaeian, Gholamali Arab Hesarsheneh, Soudeh Tabashi","doi":"10.5812/aapm-157335","DOIUrl":"https://doi.org/10.5812/aapm-157335","url":null,"abstract":"<p><strong>Background: </strong>Selecting the appropriate sizes for laryngeal mask airways (LMAs) has become a concern for anesthesiologists. Traditionally, size selection has relied on factors like patient weight and gender. Nevertheless, emerging research indicates that incorporating anthropometric data could benefit the identification of the optimal LMA size for individual patients.</p><p><strong>Objectives: </strong>This randomized controlled trial aims to compare the effectiveness of LMA size selection based on weight against that determined by measuring the hyoid-cricoid distance (HCD).</p><p><strong>Methods: </strong>A total of 64 patients scheduled for eye surgery under general anesthesia were randomly assigned to two groups, each consisting of 32 participants. In the \"W group\", the size of the LMA was chosen based on the manufacturer's guidelines, which relied exclusively on the patient's weight. Conversely, in the \"HCD group\", the selection of LMA size was based on measuring the HCD. We compared postoperative complications and the ease of LMA insertion in these groups.</p><p><strong>Results: </strong>Data from 28 patients in the W group and 30 in the HCD group were analyzed. The incidence of postoperative complications was comparable between groups, with 16 patients in the W group and 12 in the HCD group experiencing complications (P = 0.1). Additionally, metrics such as the number of attempts, time to insertion, ease of insertion, peak airway pressure, and abnormal curve shape showed no statistically significant differences (P > 0.05).</p><p><strong>Conclusions: </strong>Based on the findings in this study, the method for selecting LMA size based on HCD did not statistically reduce airway complications nor did it facilitate the insertion process. We recommend conducting larger studies to further investigate this topic.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"15 1","pages":"e157335"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12117262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autologous Platelet Rich Fibrin Versus Steroid in Ultrasound-Guided Sacroiliac Joint Injection for Joint Dysfunction: Randomized Comparative Study.","authors":"Omar Sayed Fargaly, Mohamed Ahmed Hamed, Maged Labib Boules, Mohammed Awad Alsaied, Mohammed Magdy Basiony, Mohammad Omar Mostafa, Amr Hamdy Mahmoud, Mohamed Ahmed Shawky","doi":"10.5812/aapm-158219","DOIUrl":"10.5812/aapm-158219","url":null,"abstract":"<p><strong>Background: </strong>Sacroiliac joint (SIJ) discomfort is frequently treated with steroids, although the relief is often temporary. The use of platelet-rich fibrin (PRF) may aid in tissue healing and prolong pain relief.</p><p><strong>Objectives: </strong>This study aims to compare the analgesic effects of a single autologous PRF injection with the commonly used steroid in ultrasound-guided intra-articular SIJ injections.</p><p><strong>Methods: </strong>This randomized clinical trial was conducted in the Department of Anesthesiology and Pain Management at Fayoum University Hospitals. The study included 94 adult patients with SIJ dysfunction confirmed by positive diagnostic tests. All patients were randomly assigned into two equal groups to receive either an ultrasound-guided PRF injection (group P, n = 47) or a steroid injection (group S, n = 47).</p><p><strong>Results: </strong>The Visual Analog Scale (VAS) score immediately after injection in group P was 7.51 ± 0.78 (mean ± SD), while in sroup S, it was 5.91 ± 0.54, with a highly significant difference between the two groups (P < 0.001). At six months, the VAS score was 3.51 ± 0.78 in group P compared to 4.68 ± 0.63 in group S, again showing a highly significant difference (P < 0.001). There was no significant difference in the Oswestry Disability Index (ODI) between the groups at one and six months.</p><p><strong>Conclusions: </strong>Intra-articular PRF injection is an effective therapy option for SIJ-related low back pain, offering prolonged pain relief compared to steroid injections.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"15 1","pages":"e158219"},"PeriodicalIF":0.0,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Effect of SAMPE and ALDERTE Checklists on the Incidence of Complications After Discharge of Radical Prostatectomy Patients from the Post-anesthesia Care Unit (PACU).","authors":"Alireza Zareie, Parisa Moradimajd, Azam Saei, Jamileh Abolghasemi","doi":"10.5812/aapm-156738","DOIUrl":"10.5812/aapm-156738","url":null,"abstract":"<p><strong>Background: </strong>Among the available tools, the SAMPE and ALDERTE checklists have been specifically designed to facilitate timely patient discharge, minimize human error, and optimize resource utilization. Given the complexities associated with surgical care, a comparative analysis of these two checklists is essential to evaluate their efficacy in improving discharge outcomes and preventing complications.</p><p><strong>Methods: </strong>This descriptive-analytical cross-sectional study assessed the distribution of complications following radical prostatectomy surgery by utilizing the SAMPE and ALDERTE checklists for discharge from the post-anesthesia care unit (PACU). A total of 156 participants, divided into three groups of 52 individuals each, were monitored for post-discharge complications 12 hours after their discharge from the PACU across three training centers. This methodology enabled a thorough evaluation of the roles of both checklists in mitigating adverse events during the critical post-operative period.</p><p><strong>Results: </strong>No significant differences in complication rates were observed among the groups; however, bleeding and vomiting were slightly more common in the SAMPE group.</p><p><strong>Conclusions: </strong>This study concluded that neither the SAMPE nor the ALDERTE checklist provided a distinct advantage over the control group, which comprised patients routinely discharged from the same treatment center. Both checklists demonstrated similar functionalities, with each showing relative strengths in specific aspects; however, neither was found to be universally superior to the other.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"15 1","pages":"e156738"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Chamomile in Reducing the Incidence and Severity of Nausea and Vomiting After Middle Ear Surgery: A Triple-Blind Randomized Study.","authors":"Maryam Sarkhosh, Ehsan Rajabi Visroodi, Hamidreza Samaee, Motahareh Farhadi, Parisa Moradimajd","doi":"10.5812/aapm-153566","DOIUrl":"https://doi.org/10.5812/aapm-153566","url":null,"abstract":"<p><strong>Background: </strong>Nausea and vomiting are among the most common complications after surgery.</p><p><strong>Objectives: </strong>The aim of this study was to investigate the effectiveness of chamomile in reducing the incidence and severity of nausea and vomiting after middle ear surgery.</p><p><strong>Methods: </strong>A total of 110 patients who met the inclusion criteria were randomly assigned to either the chamomile or placebo group. Group A consumed chamomile drops (500 mg), while group B consumed cornstarch with 30 mL of water, one hour before surgery. The severity of nausea and frequency of vomiting were recorded at recovery (time of zero), 1, 2, 4, and 6 hours after surgery using the Rhodes Index. Data were analyzed using SPSS v.21 software, paired <i>t</i>-tests, and chi-square tests.</p><p><strong>Results: </strong>A total of 110 patients were included, with an average age of 36.14 ± 10.3 years (group A) and 34.28 ± 13.3 years (group B). There was no statistically significant difference between the chamomile and placebo groups in terms of the severity of nausea and the frequency of vomiting immediately after recovery (time of zero), 1, 2, and 6 hours after surgery (P > 0.05). However, 4 hours post-surgery, the severity of nausea in the chamomile group was lower than in the placebo group, and a statistically significant difference was observed between the two groups (P = 0.03). No gastrointestinal side effects were reported.</p><p><strong>Conclusions: </strong>Based on the results of this study, chamomile can be used to reduce nausea and vomiting after middle ear surgery, given its availability and low cost.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"14 6","pages":"e153566"},"PeriodicalIF":0.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Preemptive/Preventive Effect of Dexmedetomidine and Ketorolac on Post-operative Pain of Appendectomy Patients: A Randomized Clinical Trial.","authors":"Sepideh Pakniyat, Ghasem Mousavi, Hashem Jarineshin, Fereydoon Fekrat, Narjes Sabet, Alireza Abdullahzadeh-Baghaei","doi":"10.5812/aapm-146868","DOIUrl":"10.5812/aapm-146868","url":null,"abstract":"<p><strong>Objectives: </strong>The primary objective was to test the hypothesis that the preemptive/preventive effect of Dexmedetomidine would attenuate the post-operative pain more effectively compared to ketorolac and control groups.</p><p><strong>Methods: </strong>This study was conducted in Shahid Mohamadi Hospital. Sixty patients undergoing appendectomy operations were randomized in 3 groups. Group A received intravenous Dexmedetomidine bolus (1 μg/kg) and infusion (0.5 μg/kg/h). Group B received slow intravenous bolus ketorolac 30 mg. Group C was the control group. Post-operatively fentanyl (5µg/mL) as patient control analgesia (PCA) was provided only on demand. The primary outcome was the Visual Analogue Scale (VAS) pain scores recorded at 1, 3, 6, 12 and 24 hours postoperatively. The secondary outcome was the 24-hour cumulative fentanyl PCA dose. Tertiary outcomes; changes in blood pressure, heart rate, body temperature, SpO₂ perioperatively. Quaternary outcomes were PONV, shivering.</p><p><strong>Results: </strong>In the Dexmedetomidine group the mean ± SD pain VAS scores 1.15 ± 1.98 and 0.95 ± 1.76 were significantly lower at 12 and 24 hours after operation (P = 0.004 and P = 0.003) compared to the other two (ketorolac and control) groups. The cumulative volume dose of fentanyl PCA 21.35 ± 11.77 mL was less in the Dexmedetomidine group compared to ketorolac (28.35 ± 9.82 mL, P = 0.629) and control (40.35 ± 12.90 mL, P = 0.003) groups.</p><p><strong>Conclusions: </strong>Preemptive/preventive effects of Dexmedetomidine were greatest after operation compared to the ketorolac and control groups in the terms of pain scores and amount of analgesia needed postoperatively.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"14 6","pages":"e146868"},"PeriodicalIF":0.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opioid-Free Anesthesia for Upper Limb Surgery in Obese Patients as a Day Case Surgery: A Prospective Observational Study.","authors":"Rana Ahmed Abdelghaffar, Mohamed Ahmed Hamed, Mohammed Magdy Basiony, Mohammad Fouad Algyar, Omar Sayed Fargaly, Mohamed Ahmed Shawky","doi":"10.5812/aapm-150997","DOIUrl":"10.5812/aapm-150997","url":null,"abstract":"<p><strong>Background: </strong>Opioid-free anesthesia (OFA) is a relatively new approach, and many studies are still needed to assess its effectiveness and compare it to opioid-based anesthesia (OBA).</p><p><strong>Objectives: </strong>This study investigated the use of OFA in obese patients undergoing upper limb surgery and compares its outcomes with those of OBA.Methods:This prospective randomized clinical study included 76 obese patients with a Body Mass Index (BMI) ≥ 30 kg/m² who were scheduled for upper limb surgery. Patients were randomly assigned to receive either OFA (group A, n = 38) or OBA (group B, n = 38). The OBA group was administered propofol, fentanyl, and atracurium, while the OFA group received lidocaine, propofol, atracurium, and dexmedetomidine. All patients were mechanically ventilated, and anesthesia was maintained with isoflurane and atracurium. Primary outcomes monitored included postoperative pain [Visual Analog Scale (VAS) ≥ 4] and the number of rescue doses of tramadol. Secondary outcomes included extubation time, any cardiac events, hypoxia, postoperative nausea and vomiting (PONV), intensive care unit (ICU) admission rates, and duration of hospital stay.</p><p><strong>Results: </strong>The OFA group had significantly lower extubation time, mean arterial pressure (MAP), and heart rate (HR) compared to the OBA group. Additionally, VAS scores were significantly lower at the 30-minute and 2-hour marks after extubation (P < 0.001 and P < 0.001, respectively) in patients receiving OFA. The OFA group also experienced fewer adverse effects, required fewer rescue doses of tramadol, and had shorter hospital stays.</p><p><strong>Conclusions: </strong>Opioid-free anesthesia may result in better and safer outcomes for obese patients undergoing upper limb surgeries, with fewer postoperative complications and shorter hospital stays. However, further research is needed to fully understand the potential benefits of OFA compared to OBA.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"14 6","pages":"e150997"},"PeriodicalIF":0.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Pregabalin and Midazolam as Premedication in Children Undergoing General Anesthesia for Dental Treatment.","authors":"Maryam Hajiahmadi, Nasser Kaviani, Elahe Asnaashari Esfahani, Sanaz Rajaee","doi":"10.5812/aapm-149486","DOIUrl":"10.5812/aapm-149486","url":null,"abstract":"<p><strong>Background: </strong>Pediatric dentists employ both pharmacological and non-pharmacological behavior control methods. Despite the use of behavioral control techniques, some young children cannot undergo treatment in the office, making sedation or general anesthesia necessary. Premedication drugs can be used before general anesthesia to reduce anxiety, control pain, induce amnesia, prevent nausea, and avert potential complications. The search for the ideal premedication for children is ongoing.</p><p><strong>Objectives: </strong>This study aims to compare the effects of pregabalin and midazolam (MID) in children undergoing dental treatment under general anesthesia.</p><p><strong>Methods: </strong>This prospective, triple-blind study included 64 children aged 2 - 6 years who required dental treatment under general anesthesia. Participants who met the inclusion criteria were enrolled. One group of children received pregabalin syrup, while the other group received MID syrup. The comfort of the child during separation from the parents, ease of venous access, and degree of sedation upon entering the operating room were evaluated. Blood pressure, heart rate, and blood oxygen levels were measured at baseline and every 30 minutes thereafter. Additionally, the duration of the patient's stay in recovery until discharge was recorded and compared between the two groups. Statistical analyses were performed using chi-square, Mann-Whitney U, Fisher's exact test, and SPSS version 14 software.</p><p><strong>Results: </strong>No statistically significant differences were found between premedication with MID and pregabalin in terms of anxiety during venous access, parental separation anxiety, restlessness in recovery, duration of recovery stay, or changes in heart rate, blood pressure, and blood oxygen levels between the two groups. However, a statistically significant difference was observed between the two groups regarding the degree of sedation before entering the operating room.</p><p><strong>Conclusions: </strong>Both pregabalin and MID were effective for premedication in terms of sedation and anxiety reduction, with no significant difference between the two drugs in these outcomes.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"14 6","pages":"e149486"},"PeriodicalIF":0.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}