Analytical Sciences最新文献_第8页

Triple-template surface imprinted magnetic polymers for wide-coverage extraction of steroid hormones from human serum 用于从人体血清中大范围提取类固醇激素的三模板表面印迹磁性聚合物。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-11-11 DOI: 10.1007/s44211-024-00690-9

Li Wang, Hongyu Wu, Caihong Wang, Yunfei Ma, Zheng Xiang

{"title":"Triple-template surface imprinted magnetic polymers for wide-coverage extraction of steroid hormones from human serum","authors":"Li Wang, Hongyu Wu, Caihong Wang, Yunfei Ma, Zheng Xiang","doi":"10.1007/s44211-024-00690-9","DOIUrl":"10.1007/s44211-024-00690-9","url":null,"abstract":"<div><p>In this study, novel triple-template magnetic nanospheres by surface imprinting, called triple-template magnetic molecularly imprinted polymers (tri-MMIPs), were prepared for the detection of steroid hormones in human serum. The polymers were constructed by Fe<sub>3</sub>O<sub>4</sub> as support, estrone (E1), progesterone (PROG), and estradiol (E2) as triple templates, acrylic acid (AA) as functional monomer and ethylene glycol dimethacrylate (EGDMA) as cross-linker. The resulting tri-MMIPs were further characterized and applied as sorbents in human serum pretreatment. Coupled with ultra-high performance liquid chromatography-triple quadrupole tandem mass spectrometry (UHPLC-MS/MS) profiling after derivatization, 15 steroids (E1, 6-ketoE1, 4-OHE1, 16α-OHE1, DHEA, 4-MeOE1, PROG, PREG, 17-OHPROG, 7-DHE2, E2, 2-OHE2, 16-epiE3, E3, 2-MeOE2) were successfully quantified. The developed method exhibited a good recovery (78.9–114%) and low limit of quantitation (LLOQ, 5–10 pg/mL), which indicates a great potential for application in the analysis of multiple steroid hormones in complex biological samples.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"41 2","pages":"151 - 163"},"PeriodicalIF":1.8,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142612436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of calcite for evaluation of spectral resolution of Raman spectrometers 利用方解石评估拉曼光谱仪的光谱分辨率。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-11-08 DOI: 10.1007/s44211-024-00684-7

Nobuyasu Itoh

{"title":"Use of calcite for evaluation of spectral resolution of Raman spectrometers","authors":"Nobuyasu Itoh","doi":"10.1007/s44211-024-00684-7","DOIUrl":"10.1007/s44211-024-00684-7","url":null,"abstract":"<div><p>Raman microscopes are widely used in various fields and their spectral resolutions differ greatly depending on the system and optical components. Thus, it is important to evaluate the spectral resolution of Raman systems under measurement conditions. Although both atomic emission lines and calcites have been used for the evaluation of spectral resolution and described in some guidelines, calcite is preferable because it contains information on laser width. Calcite is a crystal with a trigonal structure and the peak width of Raman spectra is sensitive to crystallinity, so the peak width of calcite may change depending on its quality. In this study, we examined differences in the peak width of atomic emission lines and calcites as well as laser line. The peak width of calcite at ~ 1086 cm<sup>−1</sup> was wider than that of laser and atomic emission lines due to contribution of laser width and calcite itself. Among various calcite samples, calcite blocks for optical prisms showed the narrowest peak width (< 1.3 cm<sup>−1</sup>) followed by high-grade reagent calcites (1.35–1.43 cm<sup>−1</sup>) and usual-grade reagent calcites (2.23–2.53 cm<sup>−1</sup>). Although the peak width of calcite slightly changed with temperature (~ 0.2 cm<sup>−1</sup> between 5 °C and 45 °C), it was comparable to the differences among high-grade reagent calcites. Thus, calcite is preferable for evaluating spectral resolution of Raman systems but its quality requires attention.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"41 2","pages":"95 - 100"},"PeriodicalIF":1.8,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resonance-enhanced multiphoton ionization time-of-flight mass spectrometry for direct analysis of liposome-encapsulated compounds 共振增强多光子电离飞行时间质谱法，用于直接分析脂质体包裹的化合物。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-11-07 DOI: 10.1007/s44211-024-00683-8

Keishi Yamashita, Kento Sakakibara, Yuta Kouyama, Hitomi Sugiyama, Tomohiro Ueyama, Koji Nishijima, Tomohiro Uchimura

{"title":"Resonance-enhanced multiphoton ionization time-of-flight mass spectrometry for direct analysis of liposome-encapsulated compounds","authors":"Keishi Yamashita, Kento Sakakibara, Yuta Kouyama, Hitomi Sugiyama, Tomohiro Ueyama, Koji Nishijima, Tomohiro Uchimura","doi":"10.1007/s44211-024-00683-8","DOIUrl":"10.1007/s44211-024-00683-8","url":null,"abstract":"<div><p>The direct measurement of compounds encapsulated into liposomes without pretreatment allows verification of both the encapsulation efficiency and the release rate of liposomes in their original state. In the present study, the direct analysis of liposomes was conducted via resonance-enhanced multiphoton ionization time-of-flight mass spectrometry (REMPI–TOFMS). When analyte species (2-phenoxyethanol) encapsulated in liposomes were measured online, spike signals appeared in a time profile of the peak area for 2-phenoxyethanol, which suggested a dispersion of the compound in this sample. In addition, the spikes disappeared when the liposomes collapsed following the addition of a Triton X-100 aqueous solution. These results strongly suggest that the appearance of spikes arises from the compound encapsulated into the dispersed liposomes. REMPI–TOFMS has an inherent characteristic of superior selectivity, which suggests that this process would be useful for achieving a precise evaluation of the release properties of target compounds even in a liposome sample containing a large variety of components.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"41 2","pages":"173 - 178"},"PeriodicalIF":1.8,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44211-024-00683-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial neural network in optimization of bioactive compound extraction: recent trends and performance comparison with response surface methodology 人工神经网络在生物活性化合物提取优化中的应用：最新趋势及与响应面方法的性能比较。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-11-06 DOI: 10.1007/s44211-024-00681-w

Vigneshwaran Subramani, Vidisha Tomer, Gunji Balamurali, Paul Mansingh

{"title":"Artificial neural network in optimization of bioactive compound extraction: recent trends and performance comparison with response surface methodology","authors":"Vigneshwaran Subramani, Vidisha Tomer, Gunji Balamurali, Paul Mansingh","doi":"10.1007/s44211-024-00681-w","DOIUrl":"10.1007/s44211-024-00681-w","url":null,"abstract":"<div><p>Plant products and its by-products are rich source of bioactive compounds like antioxidants, flavonoids, phenolics, pigments and phytochemicals. Bioactive compound’s health-promoting properties are well studied. However, optimal extraction of bioactive compounds is a complex, labour- and time-intensive process. It is also highly sensitive to experimental variables. Predicting output variables can reduce the experimental work and has positive environmental impact. Various tools such as Response Surface Methodology (RSM), Mathematical modelling have been commonly used for optimization and predictive modelling of the extraction process. Although mathematical modelling and RSM are efficient, recent studies have used Artificial Neural Network (ANN) which is more efficient and accurate and can perform extensive predictions with high accuracy. The manuscript focuses on current trends of ANN application in optimizing the extraction of bioactive compounds. In this study, ANN and RSM have been compared in terms of their performances in optimizing and modelling the extraction of bioactive compounds from herbs, medicinal plants, fruit, vegetables, and their by-products. The findings from the literature indicate that efficiency of ANN was superior to RSM. Future researches can focus on use of ANN in industrial optimization experiments.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"41 2","pages":"101 - 117"},"PeriodicalIF":1.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

pH monitoring in high ionic concentration environments: performance study of graphene-based sensors 高离子浓度环境中的 pH 值监测：石墨烯基传感器的性能研究。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-11-02 DOI: 10.1007/s44211-024-00682-9

Xin Qi, Wei Jin, Cao Tang, Xue Xiao, Rui Li, Yanqing Ma, Lei Ma

{"title":"pH monitoring in high ionic concentration environments: performance study of graphene-based sensors","authors":"Xin Qi, Wei Jin, Cao Tang, Xue Xiao, Rui Li, Yanqing Ma, Lei Ma","doi":"10.1007/s44211-024-00682-9","DOIUrl":"10.1007/s44211-024-00682-9","url":null,"abstract":"<div><p>Graphene-based pH sensors, acclaimed for their exceptional sensitivity to environmental variations, have garnered significant interest in scientific research. However, the sensor performance in high ionic concentration environments is limited, due to the Debye length ion screening effect. In this study, an innovative graphene channel pH sensing device was developed and modified by cross-linked poly(methyl methacrylate) (PMMA). Furthermore, even in high ionic concentrations, the pH value can be precisely measured by this sensor. The sensor has remarkable sensitivity, and high response rate of − 70.49 mV/pH within the pH range from 7 to 10. Notably, the sensors retain uniform response direction and sensitivity under different ionic concentrations environmental and maintain consistent reversibility and stability. This advancement in sensor technology paves the way for broader applications in complex ionic environments.</p><h3>Graphical abstract</h3><p>Left : A graphene-based pH sensor modified with a cross-linked PMMA film; Right : Sensitivity comparison of graphene-based sensors to pH under different electrolyte concentrations. This work presents a cross-linked PMMA film-modified graphene-based pH sensor that maintains high sensitivity even in high ionic strength environments.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"41 2","pages":"127 - 135"},"PeriodicalIF":1.8,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142563803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ionic liquid applications in analytical chemistry 离子液体在分析化学中的应用。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-10-28 DOI: 10.1007/s44211-024-00668-7

Kenta Fujii

引用次数: 0

Correction: Effect of the alkyl chain length of α,ω‑dichloroalkane on the Gibbs energy of transfer for functional groups 更正：α,ω-二氯乙烷烷基链长度对官能团转移吉布斯能的影响。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-10-22 DOI: 10.1007/s44211-024-00669-6

Kohei Uematsu, Erina Tanaka, Takanari Tanaka, Hajime Katano

引用次数: 0

Construction of all-solid-state ion-selective sensors using electrolyte-containing polymers 利用含电解质聚合物构建全固态离子选择性传感器。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-10-17 DOI: 10.1007/s44211-024-00678-5

Hiroki Ohashi, Keisei Sowa, Yuki Kitazumi, Osamu Shirai

{"title":"Construction of all-solid-state ion-selective sensors using electrolyte-containing polymers","authors":"Hiroki Ohashi, Keisei Sowa, Yuki Kitazumi, Osamu Shirai","doi":"10.1007/s44211-024-00678-5","DOIUrl":"10.1007/s44211-024-00678-5","url":null,"abstract":"<div><p>All-solid-state NO<sub>3</sub><sup>–</sup>, K<sup>+</sup>, NH<sub>4</sub><sup>+</sup>, Na<sup>+</sup>, and Ca<sup>2+</sup> ion-selective sensors (ISEs) were prepared using polyvinyl butyral (S-LEC®K KX-5). In the present case, polyvinyl butyral was used as a porous material to keep the internal solution of the respective ISE. All sensors exhibited near-Nernst responses in the concentration region between approximately 10<sup>–5</sup> and 0.1 mol dm<sup>–3</sup>. To avoid the influence of KCl as interfering ions, MgSO<sub>4</sub> was used as an electrolyte within the salt bridge. Although the liquid junction potential was generated, the potential difference was stabilized within about few minutes. The NO<sub>3</sub><sup>–</sup>-ISE showed high stability with no potential drift during 12 h of continuous measurements and maintained high sensitivity even after 3 weeks of storage in ultrapure water. Solidification of the internal solution is expected to make the sensor smaller and increase its mechanical strength. As an actual measurement, the sodium concentration in plasma samples using the Na<sup>+</sup>-ISE was measured to confirm agreement with literature values.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"41 1","pages":"71 - 78"},"PeriodicalIF":1.8,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Kinetic study on bimolecular photochemical quenching of tris(2,2′-bipyridyl)ruthenium(II) complex in water–ethylene glycol binary media 水-乙二醇二元介质中三(2,2'-联吡啶)钌(II)复合物双分子光化学淬灭的动力学研究。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-10-17 DOI: 10.1007/s44211-024-00680-x

Yuki Hamano, Takuhiro Otsuka, Takeshi Higashiguchi, Nobuo Uehara, Arinori Inagawa

{"title":"Kinetic study on bimolecular photochemical quenching of tris(2,2′-bipyridyl)ruthenium(II) complex in water–ethylene glycol binary media","authors":"Yuki Hamano, Takuhiro Otsuka, Takeshi Higashiguchi, Nobuo Uehara, Arinori Inagawa","doi":"10.1007/s44211-024-00680-x","DOIUrl":"10.1007/s44211-024-00680-x","url":null,"abstract":"<div><p>The bimolecular photochemical quenching of the tris(2,2′-bipyridyl)ruthenium (II) complex by ferricyanide ions in water–ethylene glycol binary media was investigated using a spectrophotometric approach, as previously reported by our research group. Time-resolved spectroscopy revealed that dynamic photochemical quenching occurred via a diffusion-dominated pathway. The static quenching process was found to occur significantly when the concentration of ethylene glycol was greater than 40 wt%. The analysis of the Stern–Volmer plots revealed that the emitters and quenchers tended to show ionic associations in water–ethylene glycol compared to our previous results with a water–glycerol binary solvent system. This is attributed to hydrophobicity, which is consistent with pioneering works that report that the addition of ethylene glycol to pure water forms hydrophobic regions, leading to dehydration of the complex ions.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"41 2","pages":"165 - 172"},"PeriodicalIF":1.8,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aptasensor based on cascaded fluorescent sensor assisted by exonuclease III for ultra-sensitive detection of Hg2+ 基于外切酶 III 辅助级联荧光传感器的光传感器，用于超灵敏检测 Hg2。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-10-11 DOI: 10.1007/s44211-024-00677-6

Xing Liu, Zhen Liu, Yiliang Pan, Xilin Xiao

{"title":"Aptasensor based on cascaded fluorescent sensor assisted by exonuclease III for ultra-sensitive detection of Hg2+","authors":"Xing Liu, Zhen Liu, Yiliang Pan, Xilin Xiao","doi":"10.1007/s44211-024-00677-6","DOIUrl":"10.1007/s44211-024-00677-6","url":null,"abstract":"<div><p>Construct a sensitive and rapid detection fluorescence biosensor with the assistance of exonuclease III to achieve efficient detection of Hg<sup>2+</sup>. Nucleic acid aptamer H0 specifically recognizes Hg<sup>2+</sup>, and under the action of exonuclease III, H0 bound to Hg<sup>2+</sup> is hydrolyzed, which in turn fails to trigger the catalytic hairpin self-assembly amplification reaction, resulting in a decrease in the number of double-stranded DNA bound to the fluorescent dye SYBR Green I in the solution, and a decrease in the fluorescence intensity. The results showed that the concentration of Hg<sup>2+</sup> showed a good linear relationship with the fluorescence intensity of the sensing system within the range of 3.8–10 pmol/L, and the detection limit was 0.53 pmol/L. The recoveries of Xiangjiang River water used for the analysis of the actual samples were in the range of 99.57–103.58%, and the relative standard deviations of the determined values were 2.4–3.7%. The method is simple, sensitive, specific, cost-effective and can be applied to water samples.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"41 1","pages":"63 - 69"},"PeriodicalIF":1.8,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0