Analytical Sciences最新文献_第7页

Robust machine learning and ensemble learning approach to predict variation in experimental data for multiple measurements and anomalies 鲁棒机器学习和集成学习方法预测多种测量和异常实验数据的变化。

IF 2 4区化学

Analytical Sciences Pub Date : 2026-04-24 DOI: 10.1007/s44211-026-00919-9

Yuta Sakai, Motosuke Katayama, Hiromasa Kaneko

{"title":"Robust machine learning and ensemble learning approach to predict variation in experimental data for multiple measurements and anomalies","authors":"Yuta Sakai, Motosuke Katayama, Hiromasa Kaneko","doi":"10.1007/s44211-026-00919-9","DOIUrl":"10.1007/s44211-026-00919-9","url":null,"abstract":"<p>In the field of chemistry, machine learning is widely used to develop desired properties and activities <i>y</i> of compounds and products from experimental conditions <i>x</i>. As <i>y</i> is measured several times, a mathematical model is constructed with <i>y</i> as the average value of these measurements, which cannot evaluate the variability of <i>y</i>. Therefore, a method was proposed to predict the variability of <i>y</i> by creating N sub-datasets with selected <i>y</i> values for each sample and constructing multiple models. However, this method reduces prediction accuracy when there are abnormal values due to measurement errors. To address these issues, we proposed a robust method that constructs multiple sub-datasets and selects only the models with the lowest mean absolute error for predictions. Validation on a film thickness and haze (light scattering intensity) dataset showed that the proposed method outperformed conventional approaches, including those that remove anomalies in advance, in predicting both the mean and variation of <i>y</i>. The proposed method could improve accuracy in datasets with multiple values of <i>y</i> and containing abnormal values without removing samples.</p>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"42 7","pages":"599 - 607"},"PeriodicalIF":2.0,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44211-026-00919-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147760110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research on peak shift probability method based on laser-induced plasma spectroscopy 基于激光诱导等离子体光谱的峰移概率方法研究。

IF 2 4区化学

Analytical Sciences Pub Date : 2026-04-23 DOI: 10.1007/s44211-026-00915-z

Yizhe Luo, Chang Liu, Jinshan Huang, Qiguo Xiao, Hongliang Li, Hui Yang, Jian Shan

{"title":"Research on peak shift probability method based on laser-induced plasma spectroscopy","authors":"Yizhe Luo, Chang Liu, Jinshan Huang, Qiguo Xiao, Hongliang Li, Hui Yang, Jian Shan","doi":"10.1007/s44211-026-00915-z","DOIUrl":"10.1007/s44211-026-00915-z","url":null,"abstract":"<div><p>The rapid and reliable in-situ detection of trace elements relevant to nuclear materials and metal elements in environmental matrices is a major challenge in the fields of environmental monitoring, nuclear safety, and resource assessment. Element identification in Laser-induced Plasma Spectroscopy (LIPS, synonymous with Laser-induced Breakdown Spectroscopy or LIBS) can be achieved by analyzing the corresponding peak information emitted by the plasma. However, due to differences in spectral databases (e.g., wavelength shift), making quick judgments remains challenging. To tackle this issue, we developed a novel data analysis strategy that explicitly accounts for spectral peak shifts. This method was evaluated using both the Akaike and Bayesian Information Criteria (AIC/ BIC) and correlation coefficients to enhance the reliability of LIPS for aerosol analysis. This approach statistically models inevitable spectral peak shifts to establish a probabilistic identification framework, offering clear evaluative criteria for detecting key elements in complex environmental samples. Experimental results demonstrate that this method substantially lowers misidentification risks and offers a robust analytical tool for field deployment and real-time environmental screening.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"42 6","pages":"461 - 478"},"PeriodicalIF":2.0,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147760056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of okadaic acid in scallop using microfluidic-based fluorescence polarization immunoassay 基于微流体的荧光偏振免疫分析法测定扇贝中冈田酸。

IF 2 4区化学

Analytical Sciences Pub Date : 2026-04-21 DOI: 10.1007/s44211-026-00897-y

Shunsuke Chida, Kazuki Takahashi, Mao Fukuyama, Motohiro Kasuya, Ayuko Imai, Anatoly V. Zherdev, Sergei A. Eremin, Masatoshi Maeki, Akihiko Ishida, Hirofumi Tani, Koji Shigemura, Akihide Hibara, Manabu Tokeshi

{"title":"Determination of okadaic acid in scallop using microfluidic-based fluorescence polarization immunoassay","authors":"Shunsuke Chida, Kazuki Takahashi, Mao Fukuyama, Motohiro Kasuya, Ayuko Imai, Anatoly V. Zherdev, Sergei A. Eremin, Masatoshi Maeki, Akihiko Ishida, Hirofumi Tani, Koji Shigemura, Akihide Hibara, Manabu Tokeshi","doi":"10.1007/s44211-026-00897-y","DOIUrl":"10.1007/s44211-026-00897-y","url":null,"abstract":"<p>A microfluidic device-based fluorescence polarization immunoassay (FPIA) enabling rapid assay completion within 20–25 min was developed for the rapid screening of okadaic acid (OA) in shellfish. A fluorescent tracer was synthesized by conjugating OA to a fluorescent dye, and two anti-OA monoclonal antibodies (7E1 and 9G3) were evaluated to optimize assay performance. Binding activity tests revealed that the 9G3 antibody exhibited a lower dissociation constant and superior assay performance. Calibration curves were constructed, and the dynamic range and sensitivity of the assay were investigated, with particular emphasis on OA concentrations around the regulatory limit (0.16 mg/kg). The applicability of the developed FPIA to real samples was assessed through spike-recovery tests using scallop extracts. Although a slight decrease in sensitivity was observed due to the presence of methanol in the extracts, OA concentrations near the regulatory threshold could be reliably discriminated. These results demonstrate that the developed microfluidic FPIA provides a rapid and simple screening approach for determining whether OA concentrations in shellfish exceed established regulatory limits, thereby supporting routine monitoring and on-site analysis.</p>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"42 7","pages":"535 - 541"},"PeriodicalIF":2.0,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147760142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent developments in rapid diagnostic methods for pathogenic bacteria 病原菌快速诊断方法的最新进展

IF 2 4区化学

Analytical Sciences Pub Date : 2026-04-20 DOI: 10.1007/s44211-026-00894-1

Saori Nakagawa

引用次数: 0

Determination of water in organic solvents by ligand-exchange reaction of Tris(2-methyl-8-quinolinolato)indium(III) complex 三（2-甲基-8-喹啉酸）铟（III）配合物配体交换反应测定有机溶剂中水的含量。

IF 2 4区化学

Analytical Sciences Pub Date : 2026-04-20 DOI: 10.1007/s44211-026-00911-3

Nanami Watanabe, Nobuo Uehara, Arinori Inagawa

{"title":"Determination of water in organic solvents by ligand-exchange reaction of Tris(2-methyl-8-quinolinolato)indium(III) complex","authors":"Nanami Watanabe, Nobuo Uehara, Arinori Inagawa","doi":"10.1007/s44211-026-00911-3","DOIUrl":"10.1007/s44211-026-00911-3","url":null,"abstract":"<div><p>The water content of organic solvents was determined by the ligand dissociation of a tris(2-methyl-8-quinolinolato)indium(III) complex. Water in the organic solvent reacts with the indium complex to induce a ligand-exchange reaction. The fluorescence of deprotonated 2-methyl-8-quinolinol disappears when the ligand-exchange reaction forms a neutral molecule; thus, the complex can serve as a turn-off water-detection sensor. We measured the water content of various organic solvents, including ethyl acetate, 1-octanol, and ethanol. The indium complex was dissolved in a water-containing organic solvent, the fluorescence of the 8-quinolonolate ion was measured, and determination curves were constructed based on the decrease in fluorescence intensity. To demonstrate the versatility of the present method, we measured the water content of alcoholic drinks. These results are consistent with the data obtained by Karl Fischer (KF) titration. Although the limits of detection and quantification were not as low as those of the KF titration, the simple experimental setup and procedure of this method are favorable for its application.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"42 6","pages":"479 - 486"},"PeriodicalIF":2.0,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44211-026-00911-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147728151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensitive determination and discrimination of fluorinated ions using ion-transfer voltammetry 用离子转移伏安法灵敏地测定和鉴别含氟离子。

IF 2 4区化学

Analytical Sciences Pub Date : 2026-04-17 DOI: 10.1007/s44211-026-00912-2

Kohei Uematsu, Kento Tamiya, Yuki Nara, Minato Tanaka, Hajime Katano

{"title":"Sensitive determination and discrimination of fluorinated ions using ion-transfer voltammetry","authors":"Kohei Uematsu, Kento Tamiya, Yuki Nara, Minato Tanaka, Hajime Katano","doi":"10.1007/s44211-026-00912-2","DOIUrl":"10.1007/s44211-026-00912-2","url":null,"abstract":"<div><p>We propose a sensitive method for discriminating fluorinated from non-fluorinated ions using ion-transfer voltammetry. This approach employed supported liquid membranes (SLMs) impregnated with either a fluorous solvent, 1<i>H</i>,1<i>H</i>,5<i>H</i>-octafluoropentyl-1,1,2,2-tetrafluoroethyl ether (OFE), or an organic solvent, 1,6-dichlorohexane (DCH). Ion-transfer reactions of the fluorinated ion perfluorooctanoate (PFOA<sup>−</sup>) and various non-fluorinated anions were measured at both the SLM(OFE)|water (W) and SLM(DCH)|W interfaces. Fluorinated ions exhibit fluorophilicity, while non-fluorinated ions show fluorophobicity toward fluorous solvents. Consequently, the shifts in the recorded ion-transfer potentials for PFOA<sup>−</sup> and non-fluorinated ions between the SLM(OFE)|W and SLM(DCH)|W interfaces exhibited opposite trends, indicating that fluorinated ions can be readily discriminated through voltammetric measurements. Furthermore, electrochemical preconcentration of PFOA<sup>−</sup> into the SLM proved feasible, enabling sensitive determination of PFOA<sup>−</sup> by subsequent voltammetric measurement. The proposed method is simple and cost-effective, making it a promising approach for the analysis of problematic per- and polyfluoroalkyl substances.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"42 6","pages":"451 - 460"},"PeriodicalIF":2.0,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147715600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantification of glyphosate and glufosinate in human blood using the aqueous layer recovered from QuEChERS extraction 利用QuEChERS提取液回收的水层定量测定人体血液中的草甘膦和草铵膦。

IF 2 4区化学

Analytical Sciences Pub Date : 2026-04-16 DOI: 10.1007/s44211-026-00913-1

Naoki Tachiiri, Kiyotaka Usui, Sohtaro Mimasaka

{"title":"Quantification of glyphosate and glufosinate in human blood using the aqueous layer recovered from QuEChERS extraction","authors":"Naoki Tachiiri, Kiyotaka Usui, Sohtaro Mimasaka","doi":"10.1007/s44211-026-00913-1","DOIUrl":"10.1007/s44211-026-00913-1","url":null,"abstract":"<div>\u0000 \u0000 <p>The Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) method is widely used as a pretreatment technique to extract a broad range of drugs and toxicants into the acetonitrile layer. However, the aqueous layer generated during the extraction process has a high-salt content and has not been analytically explored. This study focused on the unused aqueous layer and established a method for detecting the highly polar compounds glyphosate (Gly) and glufosinate (Glu) through derivatization with 9-fluorenylmethoxycarbonyl chloride, followed by liquid chromatography–tandem mass spectrometry. Under optimized conditions, both analytes were effectively separated and detected with favorable peak shapes from 50 µL of whole blood. Calibration curves exhibited good linearity over the range of 0.1–10 µg/mL, with correlation coefficients of 0.993 for Gly and 0.994 for Glu. The lower limit of quantification for both compounds was 0.1 µg/mL. The method also demonstrated acceptable precision, accuracy, process efficiency, and stability. Herein, we demonstrate that the aqueous layer generated during the QuEChERS extraction process can serve as a valuable analytical matrix for determining Gly and Glu in blood. This method can be employed by directly adding the derivatization reagent to the aqueous layer without modifying the conventional QuEChERS extraction process. This method has the ability to reduce sample consumption by employing multiple extraction layers with distinct physicochemical characteristics. This is particularly important when only a limited number of sample volumes is available such as in fatal cases or poisoning incidents.</p>\u0000 <span>AbstractSection</span>\u0000 Graphical abstract\u0000 <div><figure><div><div><picture><img></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div>\u0000 \u0000 </div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"42 6","pages":"441 - 450"},"PeriodicalIF":2.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147696961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual electrochemical sensor based on graphene aerogel for quantification of ascorbic acid in pharmaceutical samples and uric acid in urine 基于石墨烯气凝胶的双电化学传感器用于定量药物样品中的抗坏血酸和尿液中的尿酸。

IF 2 4区化学

Analytical Sciences Pub Date : 2026-04-15 DOI: 10.1007/s44211-026-00896-z

Alejandro Gutiérrez, Mario Sánchez-Suárez, Natalia Rey-Raap, Ana Arenillas, Janet Ledesma-García, Luis Gerardo Arriaga

{"title":"Dual electrochemical sensor based on graphene aerogel for quantification of ascorbic acid in pharmaceutical samples and uric acid in urine","authors":"Alejandro Gutiérrez, Mario Sánchez-Suárez, Natalia Rey-Raap, Ana Arenillas, Janet Ledesma-García, Luis Gerardo Arriaga","doi":"10.1007/s44211-026-00896-z","DOIUrl":"10.1007/s44211-026-00896-z","url":null,"abstract":"<div>\u0000 \u0000 <p>This work presents the advantages of modifying glassy carbon electrodes with a graphene aerogel (GA) dispersed in polyethylenimine (PEI). The presence of GA entrapped in PEI produces a catalytic effect that greatly facilitates the separation of the anodic peaks of ascorbic acid (AA) and uric acid (UA), enabling their detection and quantification by differential pulse voltammetry (DPV). The result is a highly efficient dual electrochemical sensor with a sensitivity of approximately 2.13 × 10<sup>4</sup> µAM<sup>− 1</sup> for AA and 5.0 × 10<sup>4</sup> µAM<sup>− 1</sup> UA. The current response showed a linear relationship for AA when the concentration ranged from 1.0 to 10 × 10<sup>− 4</sup> M, with a minimum detection concentration of 0.25 µM and a relative standard deviation (RSD) of 2.0%. For UA, the lineal range was 1.0–15.0 × 10<sup>− 5</sup> M, with a minimum detection concentration of 9 µM and an RSD of 2.8%. The promising analytical performance, which allows the evaluation of AA and UA, enables accurate quantification of AA in pharmaceutical samples and UA in urine without the use of enzymes or pretreatment.</p>\u0000 <span>AbstractSection</span>\u0000 Graphical abstract\u0000 <div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div>\u0000 \u0000 </div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"42 6","pages":"365 - 376"},"PeriodicalIF":2.0,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44211-026-00896-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-color image analysis for quantifying fluorescence intensity in plasma membrane region of cells 定量细胞质膜区荧光强度的双色图像分析。

IF 2 4区化学

Analytical Sciences Pub Date : 2026-04-14 DOI: 10.1007/s44211-026-00908-y

Satoshi Fujii, Keita Takaki, Shinji Sueda

{"title":"Dual-color image analysis for quantifying fluorescence intensity in plasma membrane region of cells","authors":"Satoshi Fujii, Keita Takaki, Shinji Sueda","doi":"10.1007/s44211-026-00908-y","DOIUrl":"10.1007/s44211-026-00908-y","url":null,"abstract":"<div><p>Quantitative evaluation of fluorescence intensity in the plasma membrane region is essential for a wide range of cell-based imaging studies, including membrane protein analysis and cell surface interaction assays. However, accurate quantification remains challenging because membrane regions are often manually selected, leading to subjective variabilities and limited reproducibility. Here, we developed a dual-channel image analysis framework and its web-based tool, DualCellQuant, which enables the objective and reproducible quantification of fluorescence intensity in the plasma membrane region. This method integrates automated cell segmentation using Cellpose-SAM with Euclidean distance transform-based radial normalization to define membrane regions at a fixed normalized distance from the cell boundary. The membrane region was determined on a reference channel, allowing robust quantification even for low-intensity target signals. In addition, ratiometric analysis between channels can mitigate cell-to-cell variability. We applied this approach to quantify rapamycin-induced binding between FKBP12 displayed on the cell surface and fluorescein-labeled FRB, demonstrating that membrane-associated fluorescence signals can be consistently extracted on a per-cell basis and used for binding-equilibrium analysis. This accessible framework is expected to facilitate the reproducible interpretation of multicolor cellular imaging data across diverse experimental settings.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"42 7","pages":"577 - 588"},"PeriodicalIF":2.0,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44211-026-00908-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147669892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Construction of a multi-label odor prediction model based on molecular structures and olfactory receptor binding profiles with a novel interpretability framework 基于分子结构和嗅觉受体结合谱的多标签气味预测模型的构建及新的可解释性框架。

IF 2 4区化学

Analytical Sciences Pub Date : 2026-04-13 DOI: 10.1007/s44211-026-00900-6

Yuta Wakutsu, Hiromasa Kaneko

{"title":"Construction of a multi-label odor prediction model based on molecular structures and olfactory receptor binding profiles with a novel interpretability framework","authors":"Yuta Wakutsu, Hiromasa Kaneko","doi":"10.1007/s44211-026-00900-6","DOIUrl":"10.1007/s44211-026-00900-6","url":null,"abstract":"<div><p>Predicting odors from molecular structures is a long-standing challenge in chemoinformatics, especially in cases where structurally similar compounds, such as optical isomers, exhibit distinct odor perceptions. To address this, we developed a multi-stage odor prediction framework that integrates both molecular structures and olfactory receptor (OR) binding information. Recognizing that human olfaction is mediated by complex receptor–ligand interactions, we divided the process into three mechanistic stages: (1) prediction of molecular binding to ORs (classification), (2) estimation of binding strength (regression), and (3) prediction of odor presence based on receptor responses (classification). We further introduced a novel interpretability metric, Positive likeness, which estimates the contribution of specific receptors to the likelihood of each odor label. Using this framework, we demonstrated the ability to distinguish odor differences between optical isomers and to identify ORs that are potentially responsible for the perception of specific odor attributes. The model also enabled extrapolative odor prediction for molecules with unknown odor annotations, leveraging receptor information and label propagation. Our results highlight the importance of receptor-level descriptors in enhancing predictive performance and biological interpretability. This study provides a foundation for receptor-guided odor modeling and supports applications in fragrance design and sensory informatics.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"42 7","pages":"543 - 556"},"PeriodicalIF":2.0,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s44211-026-00900-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147669772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0