Analytical Sciences最新文献

{"title":"Application of cellulose sponge modified by polypyrrole for thin film microextraction of polycyclic aromatic hydrocarbons.","authors":"Mohammad Saraji, Mahsa Aghaei, Salman Javadian","doi":"10.1007/s44211-026-00975-1","DOIUrl":"https://doi.org/10.1007/s44211-026-00975-1","url":null,"abstract":"<p><p>In this work, a flexible and environmentally compatible thin film, consisted of cellulose and polypyrrole, was prepared and used as a new thin film microextraction sorbent for adsorption and determination of trace amount of methylnaphthalene, anthracene and pyrene from aqueous samples. Analytes were determined by gas chromatography equipped with a flame ionization detector. polypyrrole was used as a modifier due to its porous structure and good mechanical stability in aqueous solution. Pyrrole monomers deposited on cellulosic substrate were polymerized through oxidative chemical polymerization. Extraction of analytes from sample solution to the cellulose/poly pyrrole film was performed through π-π interactions between the sorbent and polycyclic aromatic hydrocarbons (PAHs). Extraction efficiency was studied by changing parameters such as desorption solvent, time of desorption, volume of desorption solvent, salt concentration, temperature and extraction time were optimized. The detection limits of 1.40, 0.60 and 0.45 µg L^-1 were obtained for methylnaphthalene, anthracene and pyrene, respectively. The method showed good linearity in the concentration range of 4-3000, 2-1000, and 1-500 µg L^-1 for methylnaphthalene, anthracene and pyrene, respectively. Intra- and inter-day precision were in the range of 6.0-8.0% and 12.0-15.0%, respectively. Finally, PAHs were determined in real samples by this method. Recovery for real samples was in the range of 53-102%.</p>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a rotating microfluidic device for efficient solid-phase extraction in food analysis.","authors":"Masaya Shuto, Takahiro Matsuda, Tsukasa Endo, Kazuhiro Kobayashi, Toshihiro Kasama, Madoka Takai, Ryo Miyake","doi":"10.1007/s44211-026-00976-0","DOIUrl":"https://doi.org/10.1007/s44211-026-00976-0","url":null,"abstract":"<p><p>In recent years, microchemical devices have garnered increasing attention for enabling highly efficient chemical processes using minute sample volumes while offering advantages such as compactness and low environmental impact. In this study, a rotating microfluidic device capable of processing sample volumes on the order of several hundred microliters was developed utilizing centrifugal force as the driving mechanism. The device was designed to streamline labor-intensive solid-phase extraction (SPE) procedures commonly used in food analysis pretreatment. A centrifugal microfluidic device featuring a conditioning unit for SPE column preparation and a pretreatment unit for sample processing was developed. A validation study was conducted using this device on vitamin B1 (thiamine) retained on an SPE column. The measurement results met the relevant guidelines, and the method employing this device reduced processing time compared to conventional methods. As a preliminary evaluation, ascorbic acid 2-glucoside was also tested as a flow-through-mode analyte. However, device-associated chromatographic interference precluded confirmation of the quantitative validity of the method. Thus, this device is expected to contribute to labor and space savings as well as reduced environmental impact in food analysis pretreatment. However, further device design improvements and additional validation are required to expand its range of applicable targets.</p>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy deposition rhythm for optimizing high pulse repetition frequency LIBS signals under scan speed-laser frequency interaction.","authors":"Maoyuan Pang, Jinyi Li, Weiye Yu, Yujie Zhang, Xiaomeng Li, Zhenyan Feng, Yu Ding, Xinxin Liu","doi":"10.1007/s44211-026-00974-2","DOIUrl":"https://doi.org/10.1007/s44211-026-00974-2","url":null,"abstract":"<p><p>In microjoule high pulse repetition frequency laser induced breakdown spectroscopy systems, the traditional single-variable parameter optimization method can only analyze the effects of scan speed and laser frequency independently, without considering the interaction effect between these two factors. To address this issue, an optimization strategy based on energy deposition rhythm (EDR) was proposed for the proportional optimization of scan speed and laser frequency. To begin with, the interaction between scan speed and laser frequency was analyzed using two-factor analysis of variance. Based on this, the effects of proportionally increasing scan speed and laser frequency on spectral signals were investigated by maintaining a constant ratio between the two parameters under different EDR conditions, followed by quantitative analysis based on the optimized spectral signals. The results indicated that, at a fixed EDR, proportional increases in scan speed and laser frequency maintained a constant spatial interval between adjacent laser pulses, thereby reducing the interference caused by pulse-spacing variations in local ablation overlap and related ablation conditions. Meanwhile, this proportional increase also resulted in a larger number of laser pulses contributing within the fixed 20 ms integration window owing to the increase in laser frequency, thereby enhancing the accumulated spectral emission while maintaining signal stability. The accumulated spectral intensities of Mg, Mn, and Fe increased by approximately 4-9, 5-10, and 4-10 times, respectively. The most pronounced quantitative improvement was observed under EDR = 1/400, where the R² values for Mg, Mn, and Fe increased from 0.8826, 0.9516, and 0.9061 to 0.9745, 0.9722, and 0.9778. This study provides a simple and broadly applicable strategy for optimizing high pulse repetition frequency LIBS signals and improving multi-element quantitative analysis performance.</p>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A correlation-based model-free method for tracking structural changes in in situ X-ray diffraction datasets.","authors":"Yuji Shiramata, Masatsugu Yoshimoto, Yuki Sada, Seiya Shimono, Hiroki Yamada, Koji Ohara, Kazuhiko Omote","doi":"10.1007/s44211-026-00970-6","DOIUrl":"https://doi.org/10.1007/s44211-026-00970-6","url":null,"abstract":"<p><p>In situ X-ray diffraction (XRD) measurements are widely used to investigate structural changes and often generate large XRD datasets. Although principal component analysis (PCA) and Rietveld refinement are effective tools for data analysis, they generally require additional physical interpretation or structural models, making the screening of large datasets challenging. To address this challenge, we propose a model-free method based on time-dependent correlation functions for directly tracking structural changes in large in situ XRD datasets without requiring crystallographic models or profile fitting. The effectiveness of the proposed method was demonstrated using in situ XRD datasets collected during the amorphization of zeolites over a temperature range from room temperature to 1000 °C. The proposed method successfully tracked dehydration and amorphization processes directly from in situ XRD datasets and showed good agreement with the trends observed in differential thermal analysis (DTA) and thermogravimetry (TG) measurements. These results demonstrate that the proposed method provides a practical tool for screening and tracking structural changes in large in situ XRD datasets.</p>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of acrylamide in food additives via Michael addition derivatization and liquid chromatography-tandem mass spectrometry.","authors":"Shimba Kawasue, Takashi Kurohara, Koji Fujihara, Shohei Takada, Yutaka Abe, Naoki Sugimoto","doi":"10.1007/s44211-026-00973-3","DOIUrl":"https://doi.org/10.1007/s44211-026-00973-3","url":null,"abstract":"<p><p>Acrylamide (AA) is a highly polar compound that exhibits poor retention and low selectivity in conventional reversed-phase LC-MS analyses. To establish a derivatization-based LC-MS/MS method for AA, we evaluated the potential of 5-(dimethylamino)-N-(2-sulfanylethyl)naphthalene-1-sulfonamide (DNS-SH) as an effective derivatization reagent and compared its performance with that of other representative thiol reagents. The ionization efficiency, the formation of product ions during collision-induced dissociation, and the progress of the reaction-as analyzed by LC-MS (MS/MS)-were accurately evaluated based on the molar ratios determined by ¹H-qNMR. The DNS derivative of AA (AA-DNS) exhibited a superior MS response than its other thiol derivatives, providing a 4-17-fold higher MS/MS signal intensity. In addition, computational studies indicate that DNS-SH has the potential to be a more effective derivatization reagent with higher reactivity. These results indicate that analytical performance is strongly influenced by the structural characteristics of thiol reagents, particularly their ionization efficiency and product-ion formation. The newly developed analytical method was applied to quantify AA in food additives subjected to heating during manufacturing, revealing that its concentration was negligible in these samples. This finding suggests that food additives contribute minimally to overall dietary exposure to AA. Thus, the proposed method provides a highly sensitive approach for determining AA.</p>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A method for determining moment values of elution peaks measured by means of high-performance liquid chromatography or capillary electrophoresis.","authors":"Kanji Miyabe, Aki Yoshikawa","doi":"10.1007/s44211-026-00971-5","DOIUrl":"https://doi.org/10.1007/s44211-026-00971-5","url":null,"abstract":"<p><p>Moment analysis of first absolute (µ_1A) and second central (µ_2C) moments of elution peaks measured by using high-performance liquid chromatography or capillary electrophoresis is effective for extracting the information about chemical phenomena relating to their separation behavior from equilibrium and kinetic points of view. It is known that elution peak profiles should be integrated to obtain more accurate values of µ_1A and µ_2C. This means that it is required to appropriately determine the range for integrating the elution peak profiles. Our research group has used a method for determining the start and end points of the integration range. However, it seems that signal noise, baseline drift, and peak asymmetry affects the selection of the integration range and the accuracy in the determination of µ_1A and µ_2C values of elution peaks. Simulated elution peaks were prepared by adding signal noise of different intensities to a base Gaussian peak and by changing the slope of baseline. Asymmetrical peaks, i.e., tailing and leading, were also prepared by using the Exponentially Modified Gaussian function while changing the degree of asymmetry. The method was applied to choose the start and end points for integrating the simulated elution peaks. Then, the values of µ_1A and µ_2C were calculated by integrating the simulated elution peak profiles in the integration range. It was tried to clarify how the magnitude of signal noise, baseline drift, and peak asymmetry affect the selection of the integration range of elution peaks and the determination of their µ_1A and µ_2C values.</p>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149073263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasensitive Cr(VI) sensing via H₂O₂-free electron-accepting pathway using atomically dispersed CuCo-NC.","authors":"Jinhua Liang, Hongying Ye, Zuhuan Yuan, Zhaodi Wu, Guizhen Li, Ruizheng Hao, Xiaoqian Wu, Shipei Cheng, Yilin Hu, Wenyuan Zhu","doi":"10.1007/s44211-026-00972-4","DOIUrl":"https://doi.org/10.1007/s44211-026-00972-4","url":null,"abstract":"<p><p>Hexavalent chromium (Cr(VI)), a highly toxic and carcinogenic environmental pollutant, poses severe threats to ecological balance and human health. Traditional colorimetric detection methods relying on peroxidase-like nanozymes often suffer from interference caused by reactive oxygen species (ROS) and coexisting redox-active substances, compromising their accuracy in complex water matrices. Herein, we report a novel H₂O₂-free colorimetric strategy for the ultrasensitive detection of Cr(VI) using atomically dispersed CuCo-NC catalysts. Unlike conventional mechanisms, the synergistic interplay between Cu and Co atoms modulates the electronic structure (d-band center), enabling Cr(VI) to act as a direct electron acceptor. This unique pathway facilitates the oxidation of TMB without generating ROS intermediates, thereby conferring exceptional resistance to common interferents such as Fe²⁺/Fe³⁺. The sensor exhibits a wide linear range (50-1000 nM) and an ultralow detection limit of 1.12 nM, surpassing many existing methods. Furthermore, the practical applicability of this probe is validated through the successful monitoring of Cr(VI) in real water samples (e.g., Guilin Lijiang River), demonstrating its robustness for on-site environmental surveillance. This work not only provides a reliable tool for early-warning monitoring of chromium pollution but also offers mechanistic insights into H₂O₂-free catalytic pathways.</p>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149073374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: HPLC enantioseparation on composite chiral stationary phases based on homosubstituted and heterosubstituted amylose derivatives.","authors":"Shi-Yao Chen, Yi-Han Lou, Shou-Wan Tang","doi":"10.1007/s44211-026-00969-z","DOIUrl":"https://doi.org/10.1007/s44211-026-00969-z","url":null,"abstract":"","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Raman spectroscopy of metal complexes for electrochemical applications","authors":"Nobuyuki Serizawa","doi":"10.1007/s44211-026-00955-5","DOIUrl":"10.1007/s44211-026-00955-5","url":null,"abstract":"<div><div><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div></div>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":"42 10","pages":"901 - 903"},"PeriodicalIF":2.0,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148981299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An automated endpoint control platform for a cyclone concentration pipette.","authors":"Ruying Wang, Chenyu Zhou, Ryoichi Ohta, Kazuma Mawatari","doi":"10.1007/s44211-026-00967-1","DOIUrl":"https://doi.org/10.1007/s44211-026-00967-1","url":null,"abstract":"<p><p>In the point-of-care, microfluidic, and biochemistry areas, the sample volume is becoming as small as µL order. In this study, we introduce a cyclone concentration pipette that integrates quantitative concentration and sample ejection functions for liquid volume conversion (mL to µL). The concentration pipette is a three-scale polypropylene (PP) tube comprising a cm-scale cyclone concentration chamber, a mm-scale channel for keeping the 10 µL liquid, and a µm-scale orifice (105 µm ± 6 µm) for ejecting liquid. The cyclone concentration system requires continuous observation to determine the endpoint (10 µL). This work introduces an automated control system designed for precise control of a 10 µL volume. The system is built on a Raspberry Pi platform with a Logitech C920 USB camera (1920 × 1080). It monitors the tube in real-time using three parallel detection methods: a convolutional neural network (CNN) for liquid state classification, a MOG2 background subtractor for droplet movement detection, and temporal pixel variance analysis across a 40-frame rolling window for flow state monitoring. When no activity is detected by any method for 30 consecutive seconds, the Raspberry Pi automatically closes a KOGANEI proportional pneumatic valve via a PWM-to-voltage converter (0-10 V). The system automatically terminated concentration without manual intervention. For the water concentration, the mean final volume was 10.6 μL with a standard deviation of 1.65 μL, corresponding to a coefficient of variation (CV) of 15.6% and a bias of + 6.0% relative to the target volume of 10 μL (n = 10). The optimized imaging conditions improved the stability of endpoint detection and volume control, resulting in a final volume of 10.4 μL (CV = 8.2%) with a bias of + 4.0% relative to the 10 μL target, demonstrating acceptable endpoint control accuracy. For the Sunset Yellow solution, a recovery of > 90% and a concentration factor of approximately 90-fold were achieved, indicating that the automated control strategy maintained high sample recovery while achieving efficient concentration.</p>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148982088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}