Analytical Sciences最新文献

Sensitivity-enhanced potentiometric measurement by incorporating graphitic carbon nitride into the ion-to-electron transducer of potassium ion-selective electrodes.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-12-20 DOI: 10.1007/s44211-024-00705-5

Mingpeng Yang, Jinghan Cheng, Xingqiang Zhao, Jun Cai, Wangping Zhou

{"title":"Sensitivity-enhanced potentiometric measurement by incorporating graphitic carbon nitride into the ion-to-electron transducer of potassium ion-selective electrodes.","authors":"Mingpeng Yang, Jinghan Cheng, Xingqiang Zhao, Jun Cai, Wangping Zhou","doi":"10.1007/s44211-024-00705-5","DOIUrl":"https://doi.org/10.1007/s44211-024-00705-5","url":null,"abstract":"In recent years, wearable sweat sensors have garnered significant attention for real-time monitoring of human physiological information because of their ability to continuously and non-invasively detect multiple sweat biomarkers. Among these, potentiometric sensors stand out for their low power consumption, low cost, compact design, and real-time monitoring capabilities, making them an ideal alternative for sweat analysis. However, enhancing the sensitivity of ion-selective electrodes (ISEs), a critical parameter of potentiometric sensors, remains a challenging research focus. In this work, the sensitivity of K+ ISEs was significantly enhanced by doping two-dimensional nanoparticles graphitic carbon nitride (g-C₃N₄) into the ion-to-electron transducer of the electrode via electrodeposition. The calibration curve slope of the K+ potentiometric sensors with doped g-C3N4 reached 59.6 mV/dec, representing a 33% increase in sensitivity compared to the control sensor without g-C₃N₄. Furthermore, the developed sensors demonstrated excellent repeatability, and anti-interference capabilities. Finally, the feasibility of the prepared sensors was further validated in artificial sweat. The large specific surface area of g-C₃N₄ combined with the excellent conductivity of PEDOT: PSS, significantly improved the sensitivity of ISEs in this study. This innovative approach paves a new avenue for the application of two-dimensional materials in potentiometric sensors, potentially advancing the field of real-time sweat analysis.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficient single-channel current measurements of the human BK channel using a liposome-immobilized gold probe.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-12-20 DOI: 10.1007/s44211-024-00707-3

Minako Hirano, Mami Asakura, Toru Ide

{"title":"Efficient single-channel current measurements of the human BK channel using a liposome-immobilized gold probe.","authors":"Minako Hirano, Mami Asakura, Toru Ide","doi":"10.1007/s44211-024-00707-3","DOIUrl":"https://doi.org/10.1007/s44211-024-00707-3","url":null,"abstract":"The human BK channel (hBK) is an essential membrane protein that regulates various biological functions, and its dysfunction leads to serious diseases. Understanding the biophysical properties of hBK channels is crucial for drug development. Artificial lipid bilayer recording is used to measure biophysical properties at the single-channel level. However, this technique is time-consuming and complicated; thus, its measurement efficiency is very low. Previously, we developed a novel technique to improve the measurement efficiency by rapidly forming lipid bilayer membranes and incorporating ion channels into the membrane using a hydrophilically modified gold probe. To further improve our technique for application to the hBK channel, we combined it using the gold probe with a liposome fusion method. Using a probe on which liposomes containing hBK channels were immobilized, the channels were efficiently incorporated into the lipid bilayer membrane, and the measured channel currents showed the current characteristics of the hBK channel. This technique will be useful for the efficient measurements of the channel properties of hBK and other biologically important channels.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic labeling of RNA using ribonucleoside analogs enables the evaluation of RNA synthesis and degradation rates.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-12-19 DOI: 10.1007/s44211-024-00704-6

Hidenori Tani

引用次数: 0

Bromine isotope splitting in vibrational spectra of bromoform by time-resolved transient transmission spectroscopy.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-12-16 DOI: 10.1007/s44211-024-00702-8

W Gadomski, K Polok, K Skała, B Ratajska-Gadomska

{"title":"Bromine isotope splitting in vibrational spectra of bromoform by time-resolved transient transmission spectroscopy.","authors":"W Gadomski, K Polok, K Skała, B Ratajska-Gadomska","doi":"10.1007/s44211-024-00702-8","DOIUrl":"https://doi.org/10.1007/s44211-024-00702-8","url":null,"abstract":"The femtosecond pump-probe technique, i.e. the transient transmission spectroscopy, has been used for the first time, to detect the vibrational spectra of symmetric fundamentals ν2 and ν3 in bromoform and chloroform. The spectra were obtained by fast Fourier transforms of the time domain signals. For both, CHCl3 and CHBr3, there are four isotopologues contributing to the spectra, due to the existence of two stable isotopes; chlorine, 35Cl and 37Cl, and bromine, 79Br and 81Br, respectively. While for chloroform the isotope splitting of the ν3 spectral band can be observed even in the spontaneous Raman scattering, for bromoform it is not detectable. Herewith we show that using the time domain spectroscopy and the windowed Fourier transform method we can provide the high resolution spectrum of the ν3 fundamental in bromoform, in which the contributions of all isotopologues are well distinguishable. The data have been collected for few volume concentrations of the studied liquids diluted in the neutral solvent CCl4. It is shown that the intensity pattern of the spectra evolves with decreasing concentration and for the ν3 fundamental it reaches the natural abundance pattern at a very high dilution. The simple theoretical model, which treats the molecules in a liquid as interacting oscillators, allows us to explain the dependence of the shape of the spectrum on the strength of the intermolecular interactions.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyper-Raman spectroscopy of non-proteinogenic amino acids.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-12-13 DOI: 10.1007/s44211-024-00698-1

Tsung-Han Liu, Masanari Okuno

引用次数: 0

Extension of the molar absorption coefficient for non-ideal mixtures: an application to aqueous monovalent alcohol solutions.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-12-13 DOI: 10.1007/s44211-024-00703-7

Akifumi Ikehata

{"title":"Extension of the molar absorption coefficient for non-ideal mixtures: an application to aqueous monovalent alcohol solutions.","authors":"Akifumi Ikehata","doi":"10.1007/s44211-024-00703-7","DOIUrl":"https://doi.org/10.1007/s44211-024-00703-7","url":null,"abstract":"The hydration state of the alcohols was investigated using the extended molar absorption coefficient, which redefines the molar absorption coefficient as a differential coefficient of concentration. The extended molar absorption coefficient is a function of the concentration calculated from the difference in absorbance, and is consistent with the conventional molar absorption coefficient, allowing a complete quantitative comparison. The quantitative performance was verified using IR and NIR absorption spectra of aqueous solutions of monovalent alcohols (methanol, ethanol, 1-propanol, 2-propanol, and tert-butanol) that were soluble in water at any mixing ratio. Extended molar absorption coefficient spectra were calculated for the combination bands of water, which were further separated by multivariate curve resolution-alternating least squares (MCR-ALS) into molecular species with different peak wavenumbers: strongly hydrogen-bonded (SHB), weakly hydrogen-bonded (WHB), and free OH species. The number of water species that change when one alcohol molecule increases, i.e., the perturbed hydration number (PHN), was calculated by comparison with the conventional molar absorption coefficient of pure water. The calculated PHN indicates that the numbers of SHB and WHB species are reversed at approximately 20 wt%, and that the free OH species increase at higher alcohol concentrations and are more pronounced for alcohols with bulky alkyl groups. These results provide a quantitative answer to the long-debated question of anomalies in water-alcohol mixing.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142816997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibiotic SERS spectral analysis based on data augmentation and attention mechanism strategy.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-12-11 DOI: 10.1007/s44211-024-00695-4

Hang Zhao, Min Zhou, Chunlin Liu, Hongheng Sun, Panshuo Zhang, Jun Ma, Xiaofeng Shi

引用次数: 0

Photoionization of pyrenemethylamine-labeled oligosaccharides: a new MALDI-TOF precursor ion-type for efficient fragmentation.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-12-10 DOI: 10.1007/s44211-024-00700-w

Andreas H Franz, Nathan Ta, Ella Nguyen, Kendall Bromley, Hana Rosenblatt, Aprilrose Fabro, Geoff Lin-Cereghino

引用次数: 0

Review of the detection of pathogenic Escherichia coli based-microchip technology.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-12-09 DOI: 10.1007/s44211-024-00693-6

Xudong Xue, Yan Zhang

引用次数: 0

Simple, accurate, and precise detection of total nitrogen in surface waters using a smartphone-based analytical method.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-12-09 DOI: 10.1007/s44211-024-00696-3

Fatih Polat

{"title":"Simple, accurate, and precise detection of total nitrogen in surface waters using a smartphone-based analytical method.","authors":"Fatih Polat","doi":"10.1007/s44211-024-00696-3","DOIUrl":"https://doi.org/10.1007/s44211-024-00696-3","url":null,"abstract":"In this study, a simple, accurate, and precise analytical strategy was developed for the determination of total nitrogen (total dissolved nitrogen + particulate nitrogen) in surface waters using smartphone technology. The spectrophotometric method based on digestion with persulfate, commonly used in water analyses, was integrated with a digital image-based colorimetric detection system (DIC). To evaluate the accuracy of the total nitrogen-digital image-based colorimetric detection system (TN-DIC), results obtained from the Hach method and UV-VIS spectrophotometer were compared with the RGB values obtained from the smartphone imaging system. T-Test results indicated no statistically significant difference between the results obtained from the TN-DIC method and the standard methods. The linear range of the TN-DIC method was determined to be 0.25-5 mg/L. The analytical quality indicators of the system were established as follows: limit of detection (LOD) 0.095 ppm, limit of quantification (LOQ) 0.29 ppm, %RSD 0.32, and R2 value 0.9982. Recovery percentages (99-112%) used to measure the analytical performance of the method were calculated through spike applications at concentrations of 1 and 2 ppm in real water samples. Unlike traditional spectrophotometric methods, this smartphone-based approach is fast, simple, and cost-effective, requiring no complex equipment during analysis.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0