Analytical Sciences最新文献

A QuEChERS method based on octadecyl-bonded hectorite for the determination of ten mycotoxins in yak ghee. 基于十八烷基键合蛭石的 QuEChERS 方法测定牦牛酥油中的十种霉菌毒素。

IF 1.6 4区化学

Analytical Sciences Pub Date : 2024-09-11 DOI: 10.1007/s44211-024-00667-8

Jun Wang,Hai-Yan Yang,Jia-Jia Fan,Zi-Han Xu,Zai-Hui Pang,Yuan Feng,Na Wei

{"title":"A QuEChERS method based on octadecyl-bonded hectorite for the determination of ten mycotoxins in yak ghee.","authors":"Jun Wang,Hai-Yan Yang,Jia-Jia Fan,Zi-Han Xu,Zai-Hui Pang,Yuan Feng,Na Wei","doi":"10.1007/s44211-024-00667-8","DOIUrl":"https://doi.org/10.1007/s44211-024-00667-8","url":null,"abstract":"To develop a clean-up material suitable for high-fat food matrices for detecting mycotoxins in yak ghee, an octadecyl-bonded hectorite (Hectorite@NHCO(CH2)17CH3) was synthesized through multi-step chemical reactions. A modified QuEChERS-HPLC-MS/MS method for detecting ten mycotoxins in sesame oil in yak ghee was established using Hectorite@NHCO(CH2)17CH3 as clean-up agent. It involved extracting mycotoxin contaminants using acidified acetonitrile and employing the Hectorite@NHCO(CH2)17CH3 to remove interfering substances from the extract. The purified samples were then analyzed using HPLC-MS/MS. Within a linear range of 1.0-500 μg/kg, there was a good linear relationship between the quantification ion peak area of the target analytes and the corresponding concentrations (R2 ≥ 0.9991). The limit of detection (LOD) ranged from 0.10 μg/kg to 18.62 μg/kg and the limit of quantitation (LOQ) ranged 0.32-62.07 μg/kg. The recoveries at low, medium and high concentrations (25, 100 and 500 μg/kg) ranged from 72.2% to 113.9%, with relative standard deviations (RSD) between 3.2% and 17.5%. The intra-day and inter-day precision met experimental requirements. The proposed method was characterized by a high accuracy and precision, and it could cater to the current demand for detecting ten mycotoxins in yak ghee.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potentiometry in determining the antioxidant capacity of compounds of different hydrophilicity in the joint presence using mixed solvents and surfactants. 使用混合溶剂和表面活性剂测定不同亲水性化合物抗氧化能力的电位计。

IF 1.6 4区化学

Analytical Sciences Pub Date : 2024-09-10 DOI: 10.1007/s44211-024-00662-z

Elena Salimgareeva,Violetta Starcheusova,Elena Gerasimova,Daria Gordeeva,Alla Ivanova

{"title":"Potentiometry in determining the antioxidant capacity of compounds of different hydrophilicity in the joint presence using mixed solvents and surfactants.","authors":"Elena Salimgareeva,Violetta Starcheusova,Elena Gerasimova,Daria Gordeeva,Alla Ivanova","doi":"10.1007/s44211-024-00662-z","DOIUrl":"https://doi.org/10.1007/s44211-024-00662-z","url":null,"abstract":"In this work, for the first time, the potentiometric method was used to determine the antioxidant capacity (AOC) of compounds of different hydrophilicity in the joint presence using mixed solvents and surfactants. The AOC of model solutions of antioxidants of different hydrophilicity was determined separately and in the joint presence in the media of phosphate buffer-surfactant and mixed solvents-surfactant, using as an example the ascorbic acid and the α-tocopherol. It was shown that the surfactant Triton X-100 is able to solubilize α-tocopherol under the selected conditions, allows to obtain reproducible and accurate results, and has less effect on the equilibrium rate of the K3[Fe(CN)6]/K4[Fe(CN)6] system. Phosphate buffer-ethanol and phosphate buffer-acetonitrile media in the 3:2 ratio with Triton X-100 (5 mmol/dm3) were chosen as the analysis conditions (RSD ≤ 6%). The range of determined concentrations was (0.006-0.5) m mmol/dm3 in phosphate buffer-ethanol and (0.006-0.3) m mmol/dm3 in phosphate buffer-acetonitrile. AOC of raw materials infusions was determined in selected media. The positive correlation with the well-known Folin-Ciocalteu assay was obtained.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142224260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of stopped-flow hyper-CEST NMR method on recirculating hyperpolarization system as applied to void space analysis in polymers. 开发应用于聚合物空隙分析的循环超极化系统停流超 CEST NMR 方法。

IF 1.6 4区化学

Analytical Sciences Pub Date : 2024-09-10 DOI: 10.1007/s44211-024-00661-0

Hideaki Fujiwara,Hirohiko Imai,Atsuomi Kimura

{"title":"Development of stopped-flow hyper-CEST NMR method on recirculating hyperpolarization system as applied to void space analysis in polymers.","authors":"Hideaki Fujiwara,Hirohiko Imai,Atsuomi Kimura","doi":"10.1007/s44211-024-00661-0","DOIUrl":"https://doi.org/10.1007/s44211-024-00661-0","url":null,"abstract":"129Xe NMR spectroscopy of polymers can provide important information on void spaces, sometimes called free volume, in polymers. Unfortunately, the spectroscopy's low sensitivity has limited its widespread use in both academic and industrial research. In order to overcome such a difficult situation, hyper-CEST method which employs hyperpolarization and CEST techniques, is examined after the introduction of recirculation and subtraction modes. Alongside the incorporated stopped-flow technique, these modes were very efficient in detecting very weak hidden signals from cellulose nanofiber (CNF) and silk fibroin (SF) films and in discussing the void space in these polymers. From the analysis of detailed saturation frequency dependence in the increment of 100 Hz, the chemical shifts of hidden peaks were successfully determined to give reasonable values for the size of void space in CNF and SF. Application on thermoplastic polyurethane film also supported our method of analysis. The subtraction mode was very efficient in judging the presence or absence of any peak at a fixed saturation frequency. These facts support that the mode will surely be useful in the future exploratory study of very weak hidden signals.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of cell signaling profiles induced by DNA aptamer-based FGFR1 agonist. 基于 DNA aptamer 的 FGFR1 激动剂诱导的细胞信号谱分析。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-09-09 DOI: 10.1007/s44211-024-00660-1

Junya Hoshiyama, Yuri Hayata, Akihiro Eguchi, Jumpei Morimoto, Ryosuke Ueki, Shinsuke Sando

{"title":"Analysis of cell signaling profiles induced by DNA aptamer-based FGFR1 agonist.","authors":"Junya Hoshiyama, Yuri Hayata, Akihiro Eguchi, Jumpei Morimoto, Ryosuke Ueki, Shinsuke Sando","doi":"10.1007/s44211-024-00660-1","DOIUrl":"https://doi.org/10.1007/s44211-024-00660-1","url":null,"abstract":"DNA aptamers have attracted attention as an alternative modality for biomolecules due to their excellent target binding specificity and thermal stability, and they are also expected to be applied as artificial agonists for receptor proteins. DNA aptamer agonist TD0 targeting the receptor of fibroblast growth factor (FGFR), which plays an important role in the fields of wound healing and regenerative medicine, has been reported to induce cellular responses as well as its native ligands. However, it was also noted that there were some different responses upon long-term stimulation, suggesting that the intracellular signals induced by DNA aptamer agonist TD0 are different from those of natural ligands. In this paper, we comprehensively analyzed the intracellular signals induced by DNA aptamer agonist TD0 targeting FGFR1, and compared them with those by natural protein ligand FGF2. It was found that the intracellular signals were highly similar for short-term stimulation. On the other hand, the receptor and the downstream cellular signals showed different activation behaviors for long-time stimulation. Evaluating the stability and sustained activity of DNA aptamer agonist TD0 and FGF2 in the medium suggested that ligand stability may be important in properly regulating cellular responses.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142152986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Size-dependent As(V) adsorption of reduced graphene oxide/magnetite nanocomposites. 还原氧化石墨烯/磁铁矿纳米复合材料对 As(V) 的吸附与尺寸有关。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-09-06 DOI: 10.1007/s44211-024-00657-w

Duc Dung Mai, Thanh Loan To, Thi Hang Bui, Thi Kim Lien Nguyen, Thi Kim Phuong Luong, Thi Lan Nguyen

引用次数: 0

Fabrication of sulphur-doped graphitic carbon nitride anchored Ag@AgCl electrocatalyst for the sensing of chloramphenicol. 用于氯霉素传感的掺硫氮化石墨碳锚定 Ag@AgCl 电催化剂的制备。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-09-06 DOI: 10.1007/s44211-024-00658-9

Suparna Kallakkattil, Yarradoddappa Venkataramanappa

{"title":"Fabrication of sulphur-doped graphitic carbon nitride anchored Ag@AgCl electrocatalyst for the sensing of chloramphenicol.","authors":"Suparna Kallakkattil, Yarradoddappa Venkataramanappa","doi":"10.1007/s44211-024-00658-9","DOIUrl":"https://doi.org/10.1007/s44211-024-00658-9","url":null,"abstract":"We have developed sulphur-doped graphitic carbon nitride (S-GCN) anchored Ag@AgCl electrocatalyst through a green technique for the first time for the electrochemical sensing of chloramphenicol. The Ag@AgCl nanoparticles were synthesized using Rhoeo discolor (Tradescantia spathacea) plant extract without the use of any external halide source. As per our knowledge, this is the first time Rhoeo discolor (Tradescantia spathacea) plant extract was used for the synthesis of Ag@AgCl nanoparticles without the use of any external halide source. Using sonochemical technique, the green synthesized nanoparticle was combined with S-GCN to form Ag@AgCl/S-GCN electrocatalyst. The synthesized materials were characterized by suitable techniques such as UV-visible spectroscopy, X-ray powder diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy and elemental analysis. The electrocatalytic reduction mechanism of chloramphenicol was studied with the help of electrochemical impedance spectroscopy, cyclic voltammetry, and linear sweep voltammetry. The Ag@AgCl/S-GCN modified electrode has shown a linear response in the range of 1 to 650 μM, with a LOD of 420 <math><mtext>nM</mtext></math> . Further, the practical application of the developed sensor was analyzed using real samples such as milk and honey and satisfactory recovery rates were observed.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142144979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A fluorescent probe for monitoring carboxylesterases in pulmonary cells under permissive hypercapnia condition. 在允许性高碳酸血症条件下监测肺细胞中羧酸酯酶的荧光探针。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-09-06 DOI: 10.1007/s44211-024-00659-8

Xiao-Ping Wu, Na Yang, Qing-Qing Liu, Zhong-Quan Zhu

引用次数: 0

Separation and determination of tellurium(IV) and tellurium(VI) using reversed-phase high-performance liquid chromatography-inductively coupled plasma mass spectrometry. 利用反相高效液相色谱-电感耦合等离子体质谱法分离和测定碲（IV）和碲（VI）。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-09-05 DOI: 10.1007/s44211-024-00663-y

Tomohiro Narukawa, Ayaka Wada, Chikako Cheong, Koichi Chiba

引用次数: 0

Development of molecular sensors based on fluorescent proteins for polarized macrophages identification. 开发基于荧光蛋白的分子传感器，用于识别极化的巨噬细胞。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-09-05 DOI: 10.1007/s44211-024-00649-w

Udari Kalpana Bandaranayake, Hiroki Sato, Miho Suzuki

{"title":"Development of molecular sensors based on fluorescent proteins for polarized macrophages identification.","authors":"Udari Kalpana Bandaranayake, Hiroki Sato, Miho Suzuki","doi":"10.1007/s44211-024-00649-w","DOIUrl":"https://doi.org/10.1007/s44211-024-00649-w","url":null,"abstract":"Macrophages are a type of white blood cells that play key roles in innate immune responses as a part of cellular immunity for host defence and tissue homeostasis. To perform diverse functions, macrophages show high plasticity by transforming to polarized states. They are mainly identified as unpolarized, pro-inflammatory and antiinflammatory states and termed as M0, M1 and M2 macrophages respectively. Discriminating polarized states is important due to strict implication with inflammatory conditions resulting in many diseases as chronic inflammation, neurodegeneration, and cancer etc. Many polarization protein markers have been identified and applied to investigate expression profiles through PCR and other techniques with antibodies. However, they are time and cost consuming and sometimes show insufficient performances. We focused on the mannose receptor (CD206) as representative marker of M2 macrophage recognising terminal mannose. We developed dose dependent mannosylated fluorescent proteins (FPs) by conjugations with mannose derivative for around 20 modifiable sites on FPs surfaces. Maximum modifications did not spoil various features of FPs. We found further sensitive and specific discriminations among M2, M1 and M0 macrophages after treating polarized macrophages with adequately conditioned FPs compared to already established approaches using anti CD206 antibody through flow cytometric analysis. These results might be derived from direct ligand utilizations and increased avidity due to multivalent bindings with abundantly modified multimeric FPs. Our strategy is simple but addresses disadvantages of preceding methods. Moreover, this strategy is applicable to detect other cell surface receptors as FPs can be modified with ligands or recognizable aptamer like molecules.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142131657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of reflective fiber-optic surface plasmon resonance sensor for monitoring scale deposition. 评估用于监测鳞片沉积的反射式光纤表面等离子体共振传感器。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-09-04 DOI: 10.1007/s44211-024-00653-0

Takuya Okazaki, Miku Yokose, Yudai Ishii, Akira Ueda, Hideki Kuramitz, Tomoaki Watanabe

引用次数: 0