Analytical Sciences最新文献_第2页

Analysis of methamphetamine in urine by GC/MS coupled with solid-phase dispersive extraction and solid-phase derivatization. 利用气相色谱/质谱结合固相分散萃取和固相衍生化技术分析尿液中的甲基苯丙胺。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-09-27 DOI: 10.1007/s44211-024-00675-8

Koichi Saito, Noriko Segawa, Rie Ito

{"title":"Analysis of methamphetamine in urine by GC/MS coupled with solid-phase dispersive extraction and solid-phase derivatization.","authors":"Koichi Saito, Noriko Segawa, Rie Ito","doi":"10.1007/s44211-024-00675-8","DOIUrl":"https://doi.org/10.1007/s44211-024-00675-8","url":null,"abstract":"In this study, we investigated a solid-phase dispersive extraction (SPDE) method and solid-phase derivatization method using the same solid-phase gel to extract methamphetamine (MA) from urine samples more efficiently and perform trifluoroacetic acid (TFA) derivatization for MA analysis by gas chromatography/mass spectrometry (GC/MS). N-Methylbenzylamine (NMe-BA) was added to the urine sample as a surrogate, and MA was extracted by SPDE using Oasis® HLB gel as a solid-phase agent. After drying the solid-phase gel of the SPDE, anhydrous TFA was added to the MA-absorbed HLB gel in order to derivatize MA with TFA on the solid-phase, followed by elution of the TFA derivative from this gel using ethyl acetate. As a validation of the analytical method, the limit of detection (S/N = 3) and the limit of quantification (S/N > 10) of MA were 0.002 µg/mL and 0.01 µg/mL, respectively. And the average recovery rate was 97.6-100.1%, repeatability was 5.6-10.7%, and intermediate precision was 10.1-11.4% for low (0.02 µg/mL), intermediate (0.1 µg/mL), and high (1 µg/mL) concentrations of MA added in urine. The developed pretreatment method enabled continuous extraction, cleanup, and TFA derivatization of urinary MA on the same solid-phase. Thus, urinary MA can be analyzed easily, rapidly, and with high sensitivity and accuracy.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing the sensitivity of immunoassays toward single-cell secretion analysis 提高单细胞分泌分析免疫测定的灵敏度。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-09-24 DOI: 10.1007/s44211-024-00651-2

Masato Suzuki

引用次数: 0

Preparation of a covalent organic framework-modified silica-gel composite for the effective adsorption of Pd(II), Zr(IV) and Mo(VI) from nitric acid solution. 制备共价有机框架修饰的二氧化硅凝胶复合材料，用于有效吸附硝酸溶液中的钯（II）、锆（IV）和钼（VI）。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-09-20 DOI: 10.1007/s44211-024-00666-9

Hao Wu, Naoki Osawa, Masahiko Kubota, Seong-Yun Kim

引用次数: 0

Ultrahigh-sensitivity vinyl-COF fluorescent sensor for trace organic arsenic detection. 用于痕量有机砷检测的超高灵敏度乙烯基-COF 荧光传感器。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-09-19 DOI: 10.1007/s44211-024-00671-y

Wenyang Li, Qiangrong Xie

{"title":"Ultrahigh-sensitivity vinyl-COF fluorescent sensor for trace organic arsenic detection.","authors":"Wenyang Li, Qiangrong Xie","doi":"10.1007/s44211-024-00671-y","DOIUrl":"https://doi.org/10.1007/s44211-024-00671-y","url":null,"abstract":"Recently, the misuse of organic arsenic feed additives, such as roxarsone (ROX), has increasingly jeopardized both human health and the environment. In response, a unique electron-rich pyrazine-cored fluorescent covalent organic framework (COF) nanosheet, named as COF-TMP, was synthesized using an alkali-catalyzed reaction between 2, 3, 5, 6-tetramethylpyrazine (TMP) and terephthalaldehyde (TPA). Characterization demonstrated that COF-TMP boasted high porosity, pronounced fluorescence, and an abundance of (E)-2-styrylpyrazine (SPA) groups. These attributes render it an exceptional fluorescent sensor for the ultrahigh sensitivity detection of electron-deficient ROX molecules. The limit of detection (LOD) for COF-TMP in detecting ROX was found to be 0.015 ppb through fluorescence-quenching titration experiments-surpassing all previously reported fluorescent sensors. A combination of experimental results and theoretical calculations suggests that the extraordinary detection capability of COF-TMP for ROX arises from a static quenching mechanism. This study paves the way not only for a novel pyrazine-based fluorescent COF nanosheet with high porosity, exceptional fluorescent capabilities, and abundant SPA groups suitable for highly sensitive and selective ROX detection but also hints at its potential application as a fluorescent sensor for environmental pollution management and related domains.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemiluminescence detection of kanamycin by DNA aptamer regulating peroxidase-like activity of Co3O4 nanoparticles. 通过 DNA 配体调节 Co3O4 纳米粒子的过氧化物酶样活性对卡那霉素进行化学发光检测。

IF 1.6 4区化学

Analytical Sciences Pub Date : 2024-09-17 DOI: 10.1007/s44211-024-00672-x

Xuxin Zhang,Yihao Li,Shaojie Xia,Zhenyuan Yang,Baiyun Zhang,Yonghong Wang

{"title":"Chemiluminescence detection of kanamycin by DNA aptamer regulating peroxidase-like activity of Co3O4 nanoparticles.","authors":"Xuxin Zhang,Yihao Li,Shaojie Xia,Zhenyuan Yang,Baiyun Zhang,Yonghong Wang","doi":"10.1007/s44211-024-00672-x","DOIUrl":"https://doi.org/10.1007/s44211-024-00672-x","url":null,"abstract":"Kanamycin (KAN) is widely used as a growth hormone analog and an antibacterial agent. However, abuse of this substance has resulted in the accumulation of excessive residue levels in foods of animal origin, which presents a significant risk to human health. A chemiluminescent aptasensor was constructed for the rapid quantitative detection of KAN by combining the properties of Co3O4 nanoparticles (Co3O4 NPs) nanozyme activity and DNA aptamer with high specificity. The DNA aptamer/Co3O4 NPs nanozyme regulated the chemiluminescence signal by exploiting the chemiluminescent properties of luminol oxidation by H2O2. Specific binding of KAN to the aptamer led to the formation of a steric hindrance block in the solution, which inhibited the activity of nanozyme and reduced signal intensity. The degree of signal reduction is related to the concentration of KAN. Under optimal conditions, there was good linearity between KAN concentration and chemiluminescence signal intensity in the range of 0.5-8.0 μΜ, with a detection limit of 0.26 μΜ. The detection system performed well in the presence of competing antibiotics and was virtually unaffected. The method was also suitable for the detection of KAN in milk samples with sample recoveries of 97.8%-99.1%. The chemiluminescence sensor has the advantages of low cost, specificity, and sensitivity, and does not require an external light source or modification of the nucleic acid aptamer which makes it a promising candidate for applications in the field of food detection.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lateral flow immunoassay device to detect staphylococcal enterotoxin B (SEB) in durian candy. 检测榴莲糖中的葡萄球菌肠毒素 B (SEB) 的侧流免疫测定装置。

IF 1.6 4区化学

Analytical Sciences Pub Date : 2024-09-13 DOI: 10.1007/s44211-024-00665-w

Paquito E Relox,Katherine Ann C Israel,Yuki Hiruta,Daniel Citterio

{"title":"Lateral flow immunoassay device to detect staphylococcal enterotoxin B (SEB) in durian candy.","authors":"Paquito E Relox,Katherine Ann C Israel,Yuki Hiruta,Daniel Citterio","doi":"10.1007/s44211-024-00665-w","DOIUrl":"https://doi.org/10.1007/s44211-024-00665-w","url":null,"abstract":"Staphylococcal enterotoxin B (SEB), a potent enterotoxin produced by Staphylococcus aureus, has been implicated in incidences of Staphylococcal food poisoning in the Philippines. The use of lateral flow immunoassay devices to detect this toxin in solid food samples, like durian candy, at the point of sampling is constrained by the requirement for sample purification (e.g. centrifugation). This problem is also true with the other applications of LFIA devices on food samples. To overcome this challenge, a lateral flow immunoassay (LFIA) device capable of detecting SEB in unpurified durian candy sample was developed in this study. A modified LFIA device was assembled with three layers of glass fiber pads functioning as sample pads instead of a conventional cellulose fiber pad. Unlike with the cellulose fiber pad, the glass fiber sample pads acted as filter and allowed the flow of a 1:5 dilution of durian candy. The LFIA device applied to spiked 1:5 diluted durian candy samples achieved a visual limit of detection of 5 ng/mL for SEB, which is twofold lower than reported for previous LFIA devices designed to detect SEB in food samples.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low-tech innovation: biomimetic solid-contact potentiometric sensor for nanomolar-level atrazine detection. 低技术创新：用于检测纳摩尔级莠去津的仿生物固体接触电位传感器。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2024-09-12 DOI: 10.1007/s44211-024-00664-x

Anjana Kolarveetil Rajagopalan, Saumya Varghese, Aneesh Padmanabhan, Theertha Thayyullathil

{"title":"Low-tech innovation: biomimetic solid-contact potentiometric sensor for nanomolar-level atrazine detection.","authors":"Anjana Kolarveetil Rajagopalan, Saumya Varghese, Aneesh Padmanabhan, Theertha Thayyullathil","doi":"10.1007/s44211-024-00664-x","DOIUrl":"https://doi.org/10.1007/s44211-024-00664-x","url":null,"abstract":"Despite the fact that there are already a number of solid-contact-based ion-selective electrodes designed for atrazine detection, our ground-breaking contribution lies in introducing the first-ever atrazine potentioselectrode, enabling the ultra-sensitive detection of atrazine at nanomolar levels. Solid-contact ion-selective electrodes can offer advantages, such as improved stability, reproducibility, sensitivity, and selectivity compared to their liquid-contact counterparts. Here, a biomimetic potentiometric sensor for Atrazine was developed using economic, light weight, and flexible carbon cloth as solid-contact material. Our methodology entails the synthesis of a molecularly imprinted polymer (MIP) through straightforward precipitation polymerization, showcasing a streamlined and efficient method for creating highly specific molecular recognition elements. The validation of template removal is confirmed via meticulous analysis employing EDX and FTIR techniques, ensuring the efficacy of our methodology. The resulting sensing membrane are casted by dispersing the MIP in 2-nitrophenyl octyl ether plasticizer and embedding it within a PVC matrix containing sodium tetraphenyl borate as a lipophilic additive. The developed sensor responds to atrazine in the pH range of 2.8-3.3 over a wide concentration range of 1 × 10-8 M to 1 × 10-5 M & 1 × 10-5 M to 1 × 10-1 M with respective slopes of 29.2 mv & 58.7 mV and a limit of detection of 1 × 10-9 M. An impressive feature of this sensor lies in its swift response time, registering a rapid reaction within a mere 10 s. Emphasize the sensor's commendable attributes of reproducibility, selectivity, and sensitivity underscoring its successful application in field monitoring.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A QuEChERS method based on octadecyl-bonded hectorite for the determination of ten mycotoxins in yak ghee. 基于十八烷基键合蛭石的 QuEChERS 方法测定牦牛酥油中的十种霉菌毒素。

IF 1.6 4区化学

Analytical Sciences Pub Date : 2024-09-11 DOI: 10.1007/s44211-024-00667-8

Jun Wang,Hai-Yan Yang,Jia-Jia Fan,Zi-Han Xu,Zai-Hui Pang,Yuan Feng,Na Wei

{"title":"A QuEChERS method based on octadecyl-bonded hectorite for the determination of ten mycotoxins in yak ghee.","authors":"Jun Wang,Hai-Yan Yang,Jia-Jia Fan,Zi-Han Xu,Zai-Hui Pang,Yuan Feng,Na Wei","doi":"10.1007/s44211-024-00667-8","DOIUrl":"https://doi.org/10.1007/s44211-024-00667-8","url":null,"abstract":"To develop a clean-up material suitable for high-fat food matrices for detecting mycotoxins in yak ghee, an octadecyl-bonded hectorite (Hectorite@NHCO(CH2)17CH3) was synthesized through multi-step chemical reactions. A modified QuEChERS-HPLC-MS/MS method for detecting ten mycotoxins in sesame oil in yak ghee was established using Hectorite@NHCO(CH2)17CH3 as clean-up agent. It involved extracting mycotoxin contaminants using acidified acetonitrile and employing the Hectorite@NHCO(CH2)17CH3 to remove interfering substances from the extract. The purified samples were then analyzed using HPLC-MS/MS. Within a linear range of 1.0-500 μg/kg, there was a good linear relationship between the quantification ion peak area of the target analytes and the corresponding concentrations (R2 ≥ 0.9991). The limit of detection (LOD) ranged from 0.10 μg/kg to 18.62 μg/kg and the limit of quantitation (LOQ) ranged 0.32-62.07 μg/kg. The recoveries at low, medium and high concentrations (25, 100 and 500 μg/kg) ranged from 72.2% to 113.9%, with relative standard deviations (RSD) between 3.2% and 17.5%. The intra-day and inter-day precision met experimental requirements. The proposed method was characterized by a high accuracy and precision, and it could cater to the current demand for detecting ten mycotoxins in yak ghee.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potentiometry in determining the antioxidant capacity of compounds of different hydrophilicity in the joint presence using mixed solvents and surfactants. 使用混合溶剂和表面活性剂测定不同亲水性化合物抗氧化能力的电位计。

IF 1.6 4区化学

Analytical Sciences Pub Date : 2024-09-10 DOI: 10.1007/s44211-024-00662-z

Elena Salimgareeva,Violetta Starcheusova,Elena Gerasimova,Daria Gordeeva,Alla Ivanova

{"title":"Potentiometry in determining the antioxidant capacity of compounds of different hydrophilicity in the joint presence using mixed solvents and surfactants.","authors":"Elena Salimgareeva,Violetta Starcheusova,Elena Gerasimova,Daria Gordeeva,Alla Ivanova","doi":"10.1007/s44211-024-00662-z","DOIUrl":"https://doi.org/10.1007/s44211-024-00662-z","url":null,"abstract":"In this work, for the first time, the potentiometric method was used to determine the antioxidant capacity (AOC) of compounds of different hydrophilicity in the joint presence using mixed solvents and surfactants. The AOC of model solutions of antioxidants of different hydrophilicity was determined separately and in the joint presence in the media of phosphate buffer-surfactant and mixed solvents-surfactant, using as an example the ascorbic acid and the α-tocopherol. It was shown that the surfactant Triton X-100 is able to solubilize α-tocopherol under the selected conditions, allows to obtain reproducible and accurate results, and has less effect on the equilibrium rate of the K3[Fe(CN)6]/K4[Fe(CN)6] system. Phosphate buffer-ethanol and phosphate buffer-acetonitrile media in the 3:2 ratio with Triton X-100 (5 mmol/dm3) were chosen as the analysis conditions (RSD ≤ 6%). The range of determined concentrations was (0.006-0.5) m mmol/dm3 in phosphate buffer-ethanol and (0.006-0.3) m mmol/dm3 in phosphate buffer-acetonitrile. AOC of raw materials infusions was determined in selected media. The positive correlation with the well-known Folin-Ciocalteu assay was obtained.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142224260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of stopped-flow hyper-CEST NMR method on recirculating hyperpolarization system as applied to void space analysis in polymers. 开发应用于聚合物空隙分析的循环超极化系统停流超 CEST NMR 方法。

IF 1.6 4区化学

Analytical Sciences Pub Date : 2024-09-10 DOI: 10.1007/s44211-024-00661-0

Hideaki Fujiwara,Hirohiko Imai,Atsuomi Kimura

{"title":"Development of stopped-flow hyper-CEST NMR method on recirculating hyperpolarization system as applied to void space analysis in polymers.","authors":"Hideaki Fujiwara,Hirohiko Imai,Atsuomi Kimura","doi":"10.1007/s44211-024-00661-0","DOIUrl":"https://doi.org/10.1007/s44211-024-00661-0","url":null,"abstract":"129Xe NMR spectroscopy of polymers can provide important information on void spaces, sometimes called free volume, in polymers. Unfortunately, the spectroscopy's low sensitivity has limited its widespread use in both academic and industrial research. In order to overcome such a difficult situation, hyper-CEST method which employs hyperpolarization and CEST techniques, is examined after the introduction of recirculation and subtraction modes. Alongside the incorporated stopped-flow technique, these modes were very efficient in detecting very weak hidden signals from cellulose nanofiber (CNF) and silk fibroin (SF) films and in discussing the void space in these polymers. From the analysis of detailed saturation frequency dependence in the increment of 100 Hz, the chemical shifts of hidden peaks were successfully determined to give reasonable values for the size of void space in CNF and SF. Application on thermoplastic polyurethane film also supported our method of analysis. The subtraction mode was very efficient in judging the presence or absence of any peak at a fixed saturation frequency. These facts support that the mode will surely be useful in the future exploratory study of very weak hidden signals.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0