Analytical Sciences最新文献_第3页

Determination of the damaging effect of IR radiation on DNA by electrochemical methods and investigation of this effect in the presence of chitosan.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2025-02-17 DOI: 10.1007/s44211-025-00727-7

Pelin Uysal Çalıcıoğlu, Fatma Akpınar, Kübra Gençdağ Şensoy, Şerife Gökçe Çalışkan, Mihrican Muti

{"title":"Determination of the damaging effect of IR radiation on DNA by electrochemical methods and investigation of this effect in the presence of chitosan.","authors":"Pelin Uysal Çalıcıoğlu, Fatma Akpınar, Kübra Gençdağ Şensoy, Şerife Gökçe Çalışkan, Mihrican Muti","doi":"10.1007/s44211-025-00727-7","DOIUrl":"https://doi.org/10.1007/s44211-025-00727-7","url":null,"abstract":"Infrared (IR) rays released from natural and artificial sources reach the layers of the skin and cause different effects. The most important effects of IR rays are the deterioration of the structure of proteins in the skin and the inadequacy of the skin's defense system. Early diagnosis of DNA damage caused by IR rays and discovery of products with antioxidant properties that will reduce the effects of damage are important in the prevention and treatment of possible diseases. This study aimed to determine the harmful effects of IR rays on DNA by measuring the guanine oxidation signal. Within the scope of the study, electrodes with DNA immobilized on their surfaces were exposed to IR irradiation and the change in guanine oxidation was detected electrochemically. A 57% decrease in guanine oxidation signal was observed as a result of IR exposure, and this rate decreased in the presence of chitosan. The results obtained show that chitosan is effective in preventing DNA damage caused by IR rays and suggest that chitosan-supported products can be used to protect the skin from the harmful effects of sun rays. Furthermore, molecular docking analyses indicated no interaction between chitosan and collagen protein. This suggests that the addition of chitosan to any cosmetic product applied to the skin is unlikely to induce DNA damage attributable to chitosan.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extracting accurate PDF data from in situ environment of materials using X-ray diffractometer.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2025-02-13 DOI: 10.1007/s44211-025-00728-6

Yuji Shiramata, Takayuki Konya, Kentaro Kobayashi, Yui Ishii, Satoshi Hiroi, Hiroki Yamada, Koji Ohara

{"title":"Extracting accurate PDF data from in situ environment of materials using X-ray diffractometer.","authors":"Yuji Shiramata, Takayuki Konya, Kentaro Kobayashi, Yui Ishii, Satoshi Hiroi, Hiroki Yamada, Koji Ohara","doi":"10.1007/s44211-025-00728-6","DOIUrl":"https://doi.org/10.1007/s44211-025-00728-6","url":null,"abstract":"Pair distribution function (PDF) analysis is a technique traditionally used at synchrotron radiation facilities, but it is now possible to obtain adequate measurements using laboratory-based equipment as well. In addition, cryo-furnaces that enable in situ measurements while controlling temperature have been well established for some time. PDF analysis requires data from a wide range of reciprocal space, along with measurements at short wavelengths. However, the development of time-resolved PDF measurements, which can be captured within a short time span, has also made significant progress. In this study, we demonstrate the reliability of PDF measurements using laboratory equipment and perform a local structure analysis of materials exhibiting an interesting structural phase transition in LaCu6-xAgx through temperature-dependent in situ PDF analysis. By comparing these results with those obtained from synchrotron sources, we provide further validation of the laboratory-based measurements. Our results confirm that in situ PDF measurements obtained with laboratory-based equipment are reliable and effective for studying structural disorder in various materials.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accurate evaluation of diffusion coefficient for electroactive analytes in human serum samples using nitrogen-terminated sputtered carbon film electrode.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2025-02-07 DOI: 10.1007/s44211-025-00718-8

Saki Ohta, Tomonori Ozawa, Shunsuke Shiba, Tatsuhiko Yajima, Tomoyuki Kamata, Dai Kato, Osamu Niwa

{"title":"Accurate evaluation of diffusion coefficient for electroactive analytes in human serum samples using nitrogen-terminated sputtered carbon film electrode.","authors":"Saki Ohta, Tomonori Ozawa, Shunsuke Shiba, Tatsuhiko Yajima, Tomoyuki Kamata, Dai Kato, Osamu Niwa","doi":"10.1007/s44211-025-00718-8","DOIUrl":"https://doi.org/10.1007/s44211-025-00718-8","url":null,"abstract":"We have developed an N-terminated carbon film electrode that allows accurate determination of the diffusion coefficient of electroactive molecules dissolved in a highly concentrated serum protein solution. The carbon film electrode was formed by the unbalanced magnetron sputtering (UBM) method. Then, nitrogen functional groups were introduced by employing NH3 or H2O plasma treatment. Cyclic voltammetry measurements with ferricyanide ion ([Fe(CN)6]3-) showed that the N-terminated carbon film electrode exhibited great anti-fouling property against simulated serum proteins (50 mg/mL human serum albumin and 15 mg/mL γ-globulin dissolved in 1 M KCl solution). In contrast, glassy carbon, H2O plasma-treated, and especially untreated carbon film electrodes were subject to severe electrode fouling, making it difficult to electrochemically determine the diffusion coefficient of the [Fe(CN)6]3- ion. The control experiment using less adsorptive ethylene glycol as a viscosity modifier showed that the increase in viscosity is a main factor of the decrease in diffusion coefficient for nitrogen plasma treated electrode, which is not significantly affected by the possible interaction between [Fe(CN)6]3- ions and serum proteins. Finally, we applied the electrode for the electrochemical analysis of acetaminophen dissolved in phosphate buffer (0.1 M, pH = 7.0), which suggests that NH3 plasma-treated carbon film exhibits the lowest ΔE increase when we compare ΔE with and without proteins and also a more stable peak current in continuous voltametric measurements compared with other carbon electrodes.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in electrochemiluminescence sensing for in vitro cell analysis: a review.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2025-02-07 DOI: 10.1007/s44211-025-00723-x

Kosuke Ino, Tomas Mockaitis, Ryota Shikuwa, Kimiharu Oba, Kaoru Hiramoto, Inga Morkvenaite-Vilkonciene, Hiroya Abe, Hitoshi Shiku

{"title":"Recent advances in electrochemiluminescence sensing for in vitro cell analysis: a review.","authors":"Kosuke Ino, Tomas Mockaitis, Ryota Shikuwa, Kimiharu Oba, Kaoru Hiramoto, Inga Morkvenaite-Vilkonciene, Hiroya Abe, Hitoshi Shiku","doi":"10.1007/s44211-025-00723-x","DOIUrl":"https://doi.org/10.1007/s44211-025-00723-x","url":null,"abstract":"Electrochemiluminescence (ECL) is a chemiluminescence phenomenon triggered by electrochemical reactions and is widely used for (bio)chemical analyses and electrochemical bioimaging. Compared to fluorescence sensing, ECL sensing reduces background noise by eliminating autofluorescence associated with excitation light. In addition, compared with conventional electrochemical imaging with scanning electrochemical microscopes, ECL imaging is faster as it requires no scanning. Furthermore, unlike electrode arrays, ECL devices can function without complex wiring, simplifying their construction. These characteristics render ECL sensing a useful analytical tool. Recently, ECL sensing has been widely used for in vitro cell analysis due to high demand for biochips in regenerative medicine, drug screening, and microphysiological systems. This review focuses on recent advancements in ECL-based cell analysis with applications for the detection of H2O2, respiration activity, cell adhesion, lipid membranes, and bipolar electrochemistry-based devices.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electron transfer-chemical reaction-electron transfer study of dobutamine, isoprenaline, droxidopa, and methyldopa with carbon nanotube-based electrode. 使用碳纳米管电极对多巴酚丁胺、异丙肾上腺素、屈昔多巴和甲基多巴进行电子转移-化学反应-电子转移研究。

IF 1.8 4区化学

Analytical Sciences Pub Date : 2025-02-04 DOI: 10.1007/s44211-025-00725-9

Yoka Shu, Mei Kadowaki, Hitoshi Muguruma

引用次数: 0

Design and function of boronic acid-based polyamidoamine dendrimer probes for bacteria recognition.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2025-02-03 DOI: 10.1007/s44211-025-00724-w

Ayame Mikagi, Takashi Hayashita

{"title":"Design and function of boronic acid-based polyamidoamine dendrimer probes for bacteria recognition.","authors":"Ayame Mikagi, Takashi Hayashita","doi":"10.1007/s44211-025-00724-w","DOIUrl":"https://doi.org/10.1007/s44211-025-00724-w","url":null,"abstract":"Selective bacterial recognition and early diagnosis are urgently required to address the growing problem of antimicrobial resistance and are crucial for achieving sustainable development goals (SDGs). Saccharide recognition is a promising solution because bacterial surfaces are composed of specific polysaccharides. In this study, we summarize our investigations into the use of boronic acid analogs for bacterial recognition, which shows potential for broad applications in various bacterial detection methods using nanoprobes. Methods were developed for the convenient, sensitive, and selective recognition of bacteria using spherical poly(amidoamine) dendrimers functionalized with boronic acids. We evaluated various measurement protocols (turbidity and fluorescence), interactions with bacterial surfaces (electrostatic and hydrophobic), recognition targets, and the further development of ditopic and benzoxaborole-based probes. As these methods require less than ten min, boronic acid-based recognition could serve as a powerful tool for rapid and simple clinical applications in the future. We believe that our study makes a significant contribution to the field, as the findings can be effectively applied to other studies involving boronic acid compounds or targeting bacterial surface saccharides.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analytical techniques for arsenic speciation.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2025-01-31 DOI: 10.1007/s44211-025-00722-y

Yu-Ki Tanaka, Kemmu Matsuhashi, Yasumitsu Ogra

{"title":"Analytical techniques for arsenic speciation.","authors":"Yu-Ki Tanaka, Kemmu Matsuhashi, Yasumitsu Ogra","doi":"10.1007/s44211-025-00722-y","DOIUrl":"10.1007/s44211-025-00722-y","url":null,"abstract":"Due to its toxicity, contamination with arsenic, a Group 1 carcinogen, is a significant environmental and public health issue. The toxicity of arsenic varies with its chemical form. For example, inorganic species like arsenite (AsO33-) and arsenate (AsO43-) are generally more toxic than organoarsenic compounds. However, some organoarsenic species exhibit higher toxicity than inorganic species. Therefore, the precise quantification and speciation of arsenic is necessary. Chromatographic techniques, particularly liquid chromatography coupled with inductively coupled plasma mass spectrometry (LC-ICP-MS), are widely used for arsenic speciation owing to their high sensitivity and accuracy. Gas chromatography-mass spectrometry (GC-MS) is another effective technique for detecting arsenic species after derivatization. In addition to chromatographic methods, more straightforward and cost-effective techniques are available for inorganic arsenic speciation. These include adsorption techniques, colorimetric assays such as the molybdenum blue method, hydride generation reactions, and voltammetry. Emerging technologies, such as microfluidic and electrochemical devices, enable rapid and portable analysis, facilitating in situ detection of arsenite and arsenate in environmental samples. While LC-ICP-MS remains the gold standard for comprehensive arsenic speciation, other advanced technologies provide a practical, rapid, and cost-effective approach.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnesium phosphates experienced high-temperature transition found on the CI-like carbonaceous chondrite Yamato 980115 by Raman microspectroscopy.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2025-01-31 DOI: 10.1007/s44211-025-00720-0

Hiroharu Yui, Hayato Tsychiya, Aruto Kashima, Shu-Hei Urashima, Kenichi Oguchi, Naoya Imae, Akira Yamaguchi

{"title":"Magnesium phosphates experienced high-temperature transition found on the CI-like carbonaceous chondrite Yamato 980115 by Raman microspectroscopy.","authors":"Hiroharu Yui, Hayato Tsychiya, Aruto Kashima, Shu-Hei Urashima, Kenichi Oguchi, Naoya Imae, Akira Yamaguchi","doi":"10.1007/s44211-025-00720-0","DOIUrl":"https://doi.org/10.1007/s44211-025-00720-0","url":null,"abstract":"Magnesium phosphate grains, minor accessory minerals found on the primitive meteorite Yamato 980115 (Y 980115), were investigated by Raman microspectroscopy. All magnesium phosphate grains found in the present study can be assigned to farringtonite, dehydrated magnesium phosphate Mg3(PO4)2-I. Since the Mg3(PO4)2-I is generally formed via the irreversible thermal transition from the polymorphs of Mg3(PO4)2-II and -III at above 750-800 degree Celsius, we can infer that the parent body of the Y 980115 meteorites experienced thermal alteration with such a high temperature. This result is in good accordance with the previous studies and the proposals on the alteration history of Y 980115 by the electron-beam microscope and X-ray diffraction analyses. Furthermore, the hydrated form of the magnesium phosphates of Mg3(PO4)2·4H2O, Mg3(PO4)2·8H2O, and Mg3(PO4)2·22H2O was not found in the present research, also suggesting that the extensive vaporization of the hydrated water molecules with magnesium phosphate occurred by such high-temperature thermal alteration. Since Y 980115 has been historically categorized to heavily aqueously altered CI (Ivuna-type) carbonaceous chondrites but has distinct characteristic to CI meteorites, the present result would provide further evidence to the complexed alteration history of the parent body of Y 980115 meteorite.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An imidazo-pyridin derivative as fluorescent probe for the peroxynitrite detection in pulmonary permissive hypercapnia.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2025-01-31 DOI: 10.1007/s44211-025-00721-z

Junjun Qin, Mingyue Cheng, Changlin He, Xiong Shen, Zhongquan Zhu

引用次数: 0

Method for extracting elemental sulfur in environmental water and its application to blue tide samples from Tokyo Bay, Japan.

IF 1.8 4区化学

Analytical Sciences Pub Date : 2025-01-24 DOI: 10.1007/s44211-025-00717-9

Shogo Sugahara, Hiroto Higa, Mitsuki Iwama, Yoshiyuki Nakamura, Tetsunori Inoue, Yukiko Senga, Michiko Egawa, Yasushi Seike

{"title":"Method for extracting elemental sulfur in environmental water and its application to blue tide samples from Tokyo Bay, Japan.","authors":"Shogo Sugahara, Hiroto Higa, Mitsuki Iwama, Yoshiyuki Nakamura, Tetsunori Inoue, Yukiko Senga, Michiko Egawa, Yasushi Seike","doi":"10.1007/s44211-025-00717-9","DOIUrl":"https://doi.org/10.1007/s44211-025-00717-9","url":null,"abstract":"A simple method for determining elemental sulfur in environmental water was developed and applied to seawater samples collected immediately after the occurrence of blue tides in Tokyo Bay. To investigate the concentration and extraction methods, artificial elemental sulfur was quantitatively produced by oxidizing a sulfide solution with an iodine solution, then used as a standard reagent in the experiments. To concentrate the elemental sulfur in the water sample, glass filter paper (GF/F) was used to filter and collect the elemental sulfur. The elemental sulfur was then extracted using n-hexane, the main component of petroleum ether; however, the recovery of elemental sulfur from the wet glass filter paper was low, and remained so even when the glass filter paper was dried. We, therefore, used a mixture of n-hexane and an acetone solvent, which is a hydrophilic organic solvent, for extraction and succeeded in recovering more than 90% of the elemental sulfur from the wet glass filter paper. Using this solvent mixture, we extracted and quantified elemental sulfur from seawater samples collected after the occurrence of blue tide, and detected 0.36-0.38 mgS L-1 of elemental sulfur in the near-surface layer. We also found that the elemental sulfur concentrations were higher in the surface layer than in the bottom layer. Therefore, we demonstrated that the quantification of elemental sulfur is important to better understand the blue tide phenomenon.","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143031784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0