{"title":"吖啶-尿素偶联物在体孔和二氧化硅纳米孔体系中的阴离子识别性能。","authors":"Sho Kimura, Akira Yamaguchi","doi":"10.1007/s44211-025-00784-y","DOIUrl":null,"url":null,"abstract":"<p><p>This study investigated the anion recognition properties of acridine-urea conjugate (AcU) in bulk DMSO and silica nanopore. The free AcU in bulk DMSO was in tautomeric equilibrium between fluorescent amino form (a-AcU) and non-fluorescent imino form (i-AcU). Owing to this tautomerization of AcU, the free AcU worked as fluorescence enhancement sensing by hydrogen bonds mediated complexation between urea unit and anion. The estimated dissociation constants were 1.4 ± 0.2 mM for CH<sub>3</sub>COO<sup>-</sup> and 3.1 ± 1.0 mM for H<sub>2</sub>PO<sub>4</sub><sup>-</sup>, whereas those for Cl<sup>-</sup>, ClO<sub>4</sub><sup>-</sup>, and HSO<sub>4</sub><sup>-</sup>were quite large. The hydrogen bond between urea unit and anion was also available for the anion recognition by AcU immobilized at the pore surface of mesoporous silica when the anion concentration is above 0.2 mM. In addition, we found that fluorescence of protonated a-AcU (a-AcHU<sup>+</sup>) could also be utilized for the recognition of weak acid anions over strong acid anions when the anion concentration is below 0.1 mM. The AcU@MPS with two recognition system has potential application for the anion recognition.</p>","PeriodicalId":7802,"journal":{"name":"Analytical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Anion recognition properties of acridine-urea conjugate in bulk and silica nanopore systems.\",\"authors\":\"Sho Kimura, Akira Yamaguchi\",\"doi\":\"10.1007/s44211-025-00784-y\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study investigated the anion recognition properties of acridine-urea conjugate (AcU) in bulk DMSO and silica nanopore. The free AcU in bulk DMSO was in tautomeric equilibrium between fluorescent amino form (a-AcU) and non-fluorescent imino form (i-AcU). Owing to this tautomerization of AcU, the free AcU worked as fluorescence enhancement sensing by hydrogen bonds mediated complexation between urea unit and anion. The estimated dissociation constants were 1.4 ± 0.2 mM for CH<sub>3</sub>COO<sup>-</sup> and 3.1 ± 1.0 mM for H<sub>2</sub>PO<sub>4</sub><sup>-</sup>, whereas those for Cl<sup>-</sup>, ClO<sub>4</sub><sup>-</sup>, and HSO<sub>4</sub><sup>-</sup>were quite large. The hydrogen bond between urea unit and anion was also available for the anion recognition by AcU immobilized at the pore surface of mesoporous silica when the anion concentration is above 0.2 mM. In addition, we found that fluorescence of protonated a-AcU (a-AcHU<sup>+</sup>) could also be utilized for the recognition of weak acid anions over strong acid anions when the anion concentration is below 0.1 mM. The AcU@MPS with two recognition system has potential application for the anion recognition.</p>\",\"PeriodicalId\":7802,\"journal\":{\"name\":\"Analytical Sciences\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-05-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Analytical Sciences\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1007/s44211-025-00784-y\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical Sciences","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s44211-025-00784-y","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Anion recognition properties of acridine-urea conjugate in bulk and silica nanopore systems.
This study investigated the anion recognition properties of acridine-urea conjugate (AcU) in bulk DMSO and silica nanopore. The free AcU in bulk DMSO was in tautomeric equilibrium between fluorescent amino form (a-AcU) and non-fluorescent imino form (i-AcU). Owing to this tautomerization of AcU, the free AcU worked as fluorescence enhancement sensing by hydrogen bonds mediated complexation between urea unit and anion. The estimated dissociation constants were 1.4 ± 0.2 mM for CH3COO- and 3.1 ± 1.0 mM for H2PO4-, whereas those for Cl-, ClO4-, and HSO4-were quite large. The hydrogen bond between urea unit and anion was also available for the anion recognition by AcU immobilized at the pore surface of mesoporous silica when the anion concentration is above 0.2 mM. In addition, we found that fluorescence of protonated a-AcU (a-AcHU+) could also be utilized for the recognition of weak acid anions over strong acid anions when the anion concentration is below 0.1 mM. The AcU@MPS with two recognition system has potential application for the anion recognition.
期刊介绍：
Analytical Sciences is an international journal published monthly by The Japan Society for Analytical Chemistry. The journal publishes papers on all aspects of the theory and practice of analytical sciences, including fundamental and applied, inorganic and organic, wet chemical and instrumental methods.
This publication is supported in part by the Grant-in-Aid for Publication of Scientific Research Result of the Japanese Ministry of Education, Culture, Sports, Science and Technology.
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