Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress最新文献
A Fournier, R Demontis, Y Tahiri, M Herve, P Moriniere, A Leflon, Z Abdull-Massih, H Atik, S Benelmouffok
{"title":"1 alpha OH vitamin D3 increases plasma aluminium in haemodialysed patients taking Al (OH)3.","authors":"A Fournier, R Demontis, Y Tahiri, M Herve, P Moriniere, A Leflon, Z Abdull-Massih, H Atik, S Benelmouffok","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>1 alpha OH vitamin D3 at the dose of 6 micrograms per week was given for four weeks to 16 stable patients on chronic haemodialysis with a low dialysate aluminium while taking a constant dose of Al(OH)3. A significant increase of their plasma aluminium was observed while on 1 alpha(OH)D3 therapy and during the six weeks following. This increase correlated with the cumulative dose of Al(OH)3 and duration on dialysis but not with the recent dose of Al(OH)3. The increase in plasma aluminium observed with 1 alpha(OH)D3 and after its discontinuation is more likely to be due to aluminium redistribution than to increased intestinal aluminium absorption. This effect indicates the need for close monitoring of plasma aluminium in uraemic patients treated with 1 alpha(OH)D3.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"390-4"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15105177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Tielemans, R Wens, F Collart, M Dratwa, J Smeyers-Verbeke, I Van Hooff, G De Roy, P Bergmann, D Verbeelen
{"title":"Bone scan in haemodialysis patients: relation to hyperparathyroidism and aluminium toxicity.","authors":"C Tielemans, R Wens, F Collart, M Dratwa, J Smeyers-Verbeke, I Van Hooff, G De Roy, P Bergmann, D Verbeelen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The influence of hyperparathyroidism and aluminium toxicity on bone scan scores (FS = Fogelman's score) was studied in 37 haemodialysis patients (group 1), of whom 24 had aluminium toxicity (group 2). FS, parathormone (iPTH) and aluminium status were assessed simultaneously, the latter by measuring serum aluminium before (BAl) and 48 hours after (PAl) a desferrioxamine infusion. FS correlated directly with iPTH in all groups, inversely with PAl and DAl (= PAl - BAl) in group 1; FS less than or equal to 2 was found in group 2 only (2 alpha less than 0.05). The time course of FS and aluminium concentration was also studied in 24 patients: a PAl increase was significantly associated with a FS decrease (2 alpha less than 0.001). In conclusion, hyperparathyroidism increases and aluminium toxicity decreases FS; FS less than or equal to 2 is very suggestive of aluminium toxicity.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"399-402"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15105179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Salvadori, F Martinelli, L Comparini, S Bandini, A Sodi
{"title":"Nitrate induced anaemia in home dialysis patients.","authors":"M Salvadori, F Martinelli, L Comparini, S Bandini, A Sodi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Many home dialysis patients in Florence and the surrounding area suddenly showed an unusual anaemia. All used a softener for water treatment. They demonstrated methaemoglobinaemia, Heinz bodies and reduction in plasma haptoglobin indicating Hb oxidation. Tap water analysis showed excessive nitrates. The substitution of the softeners with deionisers solved this important and unusual clinical problem.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"321-5"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15105245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J B Cannata, C Suarez Suarez, V Cuesta, R Rodriguez Roza, M T Allende, J Herrera, J Perez Llanderal
{"title":"Gastrointestinal aluminium absorption: is it modulated by the iron-absorptive mechanism?","authors":"J B Cannata, C Suarez Suarez, V Cuesta, R Rodriguez Roza, M T Allende, J Herrera, J Perez Llanderal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Gastrointestinal aluminium (A1) absorption has been proved but its mechanism is still unknown. This study investigates the pattern of A1 absorption in patients with different degrees of iron stores. We studied 29 haemodialysis patients forming three groups according to their serum ferritin values. Over seven days all patients received the same dose of aluminium hydroxide after which patients with 'low-normal' and normal serum ferritin increased their serum A1 proportionally with the increased aluminium hydroxide intake. By contrast patients with high serum ferritin did not show any change in their serum A1 values. Our results therefore suggest that a 'common pathway' of metal absorption could be implicated in A1 absorption. Serum ferritin might be a valuable predictor of different behaviour.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"354-9"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15105249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P T Fröhling, R Schmicker, F Kokot, K Vetter, J Kaschube, K H Götz, M Jacopian, K Lindenau
{"title":"Influence of phosphate restriction, keto-acids and vitamin D on the progression of chronic renal failure.","authors":"P T Fröhling, R Schmicker, F Kokot, K Vetter, J Kaschube, K H Götz, M Jacopian, K Lindenau","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Progression of renal failure was investigated in a prospective follow-up study of 60 patients with mild and 100 patients with advanced renal failure. Phosphate restriction in mild and protein restriction in advanced renal failure can delay the progression rate of patients with chronic renal insufficiency. Simultaneous administration of Vitamin D does not effect the progression. Administration of keto-acids to the low protein diet has a strong delaying effect on the progression rate.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"561-6"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15106558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Cossu, G B Sorba, M Maioli, P Tomasi, G Delitala
{"title":"Effects of naloxone infusion on gonadotrophin and prolactin concentrations in patients with chronic renal failure.","authors":"M Cossu, G B Sorba, M Maioli, P Tomasi, G Delitala","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum prolactin, luteinising hormone and follicle-stimulating hormone, determined by radioimmunoassay were measured during the infusion of 10mg naloxone or saline in eight male patients with chronic renal failure on regular dialysis and in seven normal controls. Neither saline nor naloxone caused any significant change in luteinising hormone, follicle-stimulating hormone or prolactin in patients with chronic renal failure. On the contrary, luteinising hormone secretion was significantly stimulated by naloxone in normal controls. Since naloxone is a specific antagonist of opiate receptors, the results would suggest a reduced hypothalamic opiate tone in patients with chronic renal failure. The data does not support the concept that the high circulating met-encephalin reported in chronic renal failure represents the pathogenetic cause of hyperprolactinaemia in chronic renal failure.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"608-13"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15106563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Vie, M Bonneville, R Cariou, J F Moreau, J P Soulillou
{"title":"Increased interleukin II production during kidney allograft rejection.","authors":"H Vie, M Bonneville, R Cariou, J F Moreau, J P Soulillou","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We have studied the lectin-induced production of Interleukin II (IL-2) by peripheral blood leucocytes (PBL) obtained from recipients of kidney grafts. Pre-graft values (haemodialysed patients) are similar to those of healthy individuals. After grafting and during the first year the IL-2 levels produced by PBL from recipients with well functioning grafts are very low (p less than 0.001). Years after grafting the IL-2 yields tend towards restoration. At the onset of an acute rejection the IL-2 production rises significantly. These data show that an increase in IL-2 production may play a role in the rejection process.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"1006-9"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15003370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improvement in cyclosporine handling by anti-lymphocyte globulin in the early post-operative period.","authors":"R Grundmann, P Wienand, U Hesse","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The value of prophylactic anti-lymphocyte globulin (ALG) treatment after transplantation was examined in a prospectively randomised study. The control group was treated with azathioprine and steroids only. In a third group prophylactic ALG combined with azathioprine and steroids was given for 8.7 +/- 2.25 days after transplantation and was then replaced by cyclosporine and steroids. Renal graft survival rates could be improved if the conventional immunosuppression was accompanied by ALG prophylaxis. However, additional cyclosporine treatment proved to be desirable since in this way the number of early acute rejection episodes could be further reduced.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"987-91"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15003930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y Pirson, J Ghysen, J P Cosyns, J P Squifflet, G P Alexandre, C van Ypersele de Strihou
{"title":"Aetiology and prognosis of de novo graft membranous nephropathy.","authors":"Y Pirson, J Ghysen, J P Cosyns, J P Squifflet, G P Alexandre, C van Ypersele de Strihou","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In order to investigate the aetiology and prognosis of de novo graft membranous nephropathy (DNGMN), we review 25 such cases observed among 1258 grafts. Coexistence of chronic rejection lesions and their parallel progression with DNGMN suggest that DNGMN may be part of the rejection process. DNGMN developed in 12 per cent of HLA-identical living donor recipients vs only two per cent of both haplo-identical and cadaver donor recipients; in the latter group, all DNGMN patients had less than or equal to 2 HLA-AB mismatches. Graft survival after diagnosis of DNGMN is only 49 per cent at five years. We conclude that DNGMN is associated with chronic rejection, develops preferentially in well-matched grafts and carries a rather poor prognosis.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"672-6"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15003938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Olgaard, E Langhoff, E Tvedegaard, S Madsen, M Hammer, H Daugaard, M Egfjord, J Ladefoged
{"title":"Aldosterone response to modulation of potassium in patients on dialysis or with essential hypertension.","authors":"K Olgaard, E Langhoff, E Tvedegaard, S Madsen, M Hammer, H Daugaard, M Egfjord, J Ladefoged","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This investigation demonstrates in patients with essential hypertension an abnormal response of the adrenal glands to modulation of potassium metabolism by infusion of insulin-glucose. Similar results have been reported in anephric patients, while the inverse response of non-nephrectomised patients on dialysis corresponded to that of normal subjects. It is suggested that the abnormal response of patients with essential hypertension may be of importance to the understanding of the pathogenesis of this important disease.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"815-9"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15003940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}