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Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress最新文献

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Conversion from cyclosporine to prednisolone and azathioprine. Safe or unsafe? 环孢素转化为强的松龙和硫唑嘌呤。安全还是不安全?
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress Pub Date : 1985-01-01
D Adu, J Michael, T Vlassis, P McMaster
{"title":"Conversion from cyclosporine to prednisolone and azathioprine. Safe or unsafe?","authors":"D Adu,&nbsp;J Michael,&nbsp;T Vlassis,&nbsp;P McMaster","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Out of 58 consecutive cadaveric renal allograft recipients whose initial immunosuppression was cyclosporine (Cys) and prednisolone, 18 were converted to prednisolone and azathioprine. Of these all four patients converted because of rejection lost their grafts. Renal function improved in seven patients converted because of nephrotoxicity and in six out of seven patients converted for miscellaneous reasons. Out of five patients converted electively at three months, one died of infection and three developed acute rejection episodes.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"998-1001"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15003932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polycythaemia is erythropoietin-independent after renal transplantation. 肾移植后的红细胞增多症与促红细胞生成素无关。
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress Pub Date : 1985-01-01
S Lamperi, S Carozzi, A Icardi
{"title":"Polycythaemia is erythropoietin-independent after renal transplantation.","authors":"S Lamperi,&nbsp;S Carozzi,&nbsp;A Icardi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum erythropoietin increased in 55 patients after transplantation. The serum erythropoietin decreased when the haematocrit and haemoglobin reached high levels, indicating recovery of a feed-back control system. Despite the diminution of erythropoietin, six patients demonstrated a state of erythrocytosis while the in vitro cultures of BFU-e revealed high sensitivity to the reduced doses of erythropoietin, using monocyte-free T-lymphocyte-depleted peripheral blood. In polycythaemic transplanted patients it is possible that cellular interactions stimulate an early hyperproliferation of BFR-e with a greater erythropoietin sensitivity and a partial capacity to grow in the absence of erythropoietin.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"928-31"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15003945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thromboxane B2 and beta 2-microglobulin as early indicators of renal allograft rejection. 血栓素B2和β 2微球蛋白作为肾移植排斥反应的早期指标。
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress Pub Date : 1985-01-01
H B Steinhauer, H Wilms, P Schollmeyer
{"title":"Thromboxane B2 and beta 2-microglobulin as early indicators of renal allograft rejection.","authors":"H B Steinhauer,&nbsp;H Wilms,&nbsp;P Schollmeyer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a prospective study the diagnostic value of urinary thromboxane B2 (TXB2) and beta 2-microglobulin (beta MG) in renal allograft rejection was studied in 34 patients after transplantation. Twenty-four episodes of rejection were diagnosed by clinical symptoms. The clinical diagnosis of rejection was confirmed by an increase of urinary TXB2 in 21 (88%) cases. The augmented renal excretion of TXB2 proceded the clinical signs of rejection for 2.0 +/- 0.75 days. The symptoms in the remaining three (12%) cases of supposed allograft rejection without increased urinary TXB2 were caused by non-immunological events (urinary tract infection, acute tubular necrosis). No elevated TXB2 excretion was observed during urinary tract infection, sepsis, and acute tubular necrosis whereas urinary beta MG increased during these events as during transplant rejection. Urinary TXB2 was found to be an early, specific, and sensitive marker of renal allograft rejection with greater reliability than beta MG excretion or clinical signs of rejection.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"1032-6"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15004097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune function and renal transplantation in Fabry's disease. 法布里病的免疫功能和肾移植。
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress Pub Date : 1985-01-01
D Donati, M G Sabbadini, F Capsoni, L Baratelli, D Cassani, A De Maio, G Frattini, M Martegani, L Gastaldi
{"title":"Immune function and renal transplantation in Fabry's disease.","authors":"D Donati,&nbsp;M G Sabbadini,&nbsp;F Capsoni,&nbsp;L Baratelli,&nbsp;D Cassani,&nbsp;A De Maio,&nbsp;G Frattini,&nbsp;M Martegani,&nbsp;L Gastaldi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A deficient leucocyte immunological function could cause the reported high rate of lethal infections following renal transplantation in patients affected by Fabry's disease. We have studied humoral immunity, peripheral lymphocyte subsets, mitogenic lymphocyte response in vitro and granulocyte function in three patients with Fabry's disease. The immunological state appears to be quite similar to that of the uraemic population in general, not showing any specific impairment.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"686-92"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15037773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glomerular C3b receptor loss in renal allografts. 同种异体肾移植肾小球C3b受体丧失。
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress Pub Date : 1985-01-01
F Nolasco, B Hartley, R Reuben, K Welsh
{"title":"Glomerular C3b receptor loss in renal allografts.","authors":"F Nolasco,&nbsp;B Hartley,&nbsp;R Reuben,&nbsp;K Welsh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>There is almost no data from the glomeruli of allografted kidneys with respect to changes in the CR-1 (C3b) receptor expressed on glomerular podocytes. We studied 22 renal graft biopsies from rejecting and stable allografts, using a panel of monoclonal antibodies. We found that the CR-1 expression was decreased in a focal and segmental fashion in some biopsies, particularly in rejecting kidneys. These changes correlated with the intensity of glomerular mononuclear cell infiltration, but in contrast no correlation was seen with peripheral capillary wall deposition of complement (C3). Thus, some active process is occurring in the glomeruli of rejecting grafts which affects the expression of the CR-1 receptor.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"1015-20"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14288179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computerised program to compare tolerance of dialysis patients to different dialysis schedules. 计算机程序比较透析患者对不同透析计划的耐受性。
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress Pub Date : 1985-01-01
F Lonati, B Pea, A Castellani
{"title":"Computerised program to compare tolerance of dialysis patients to different dialysis schedules.","authors":"F Lonati,&nbsp;B Pea,&nbsp;A Castellani","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the attempt to compare rapidly and easily the tolerance of dialysis patients to different dialysis schedules, we developed a computerised program for use with a personal computer. As a first application of this program we analysed the effects of long-term substitution of bicarbonate for acetate in reducing dialysis hypotension.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"335-47"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14120180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ectopic calcification. The role of parathyroid hormone. 异位钙化。甲状旁腺激素的作用。
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress Pub Date : 1985-01-01
A M De Francisco, M J Cassidy, J P Owen, H A Ellis, J R Farndon, M K Ward, D N Kerr
{"title":"Ectopic calcification. The role of parathyroid hormone.","authors":"A M De Francisco,&nbsp;M J Cassidy,&nbsp;J P Owen,&nbsp;H A Ellis,&nbsp;J R Farndon,&nbsp;M K Ward,&nbsp;D N Kerr","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 42 uraemic patients radiological skeletal survey, biochemistry and bone histology were compared before and at 6-12 months (42 patients), 12-24 months (26 patients) or 24-48 months (12 patients) after parathyroidectomy. The presence of small vessel or non-visceral soft tissue calcification was not related to the age, sex, duration of end-stage renal failure treatment, total serum calcium, magnesium, phosphate, Ca x P product, alkaline phosphatase, ionised calcium, serum aluminium, iPTH, severity of radiological and histological osteitis fibrosa or parathyroid gland weight. Twenty-three patients (55%) had small vessel and 20 (48%) soft tissue calcification before parathyroidectomy. Despite a marked improvement in subperiosteal erosions (37 healed, 5 improved) and healing of osteitis fibrosa histologically, seven patients developed new and six developed increased peripheral arterial calcification while in 10 patients non-visceral soft tissue calcification disappeared and in two decreased. Successful parathyroidectomy improves non-visceral calcification but not arterial calcification despite reduction in Ca x P product and iPTH.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"888-94"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15103702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute renal failure in an infant with partial deficiency of hypoxanthine-guanine phosphoribosyltransferase. 次黄嘌呤-鸟嘌呤磷酸核糖基转移酶部分缺乏的婴儿急性肾功能衰竭。
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress Pub Date : 1985-01-01
A M Wingen, W Löffler, R Waldherr, K Schärer
{"title":"Acute renal failure in an infant with partial deficiency of hypoxanthine-guanine phosphoribosyltransferase.","authors":"A M Wingen,&nbsp;W Löffler,&nbsp;R Waldherr,&nbsp;K Schärer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A three week old boy presented with pneumonia, weight loss, metabolic acidosis and renal failure (serum creatinine 3.1 mg/100 ml, uric acid 11.5 mg/100 ml). Renal biopsy revealed severe crystal nephropathy. Low activity of hypoxanthine-guanine phosphoribosyltransferase (HPRT) in erythrocytes and fibroblasts suggested a partial deficiency of the enzyme. A family study proved the mother to be heterozygous and the maternal grandfather to be hemizygous for HPRT deficiency. The grandfather developed gouty nephropathy and uraemia. The propositus was treated with allopurinol and kept on low purine diet and high fluid intake with sodium bicarbonate. Thereafter GFR gradually improved. At the age of two and a half years, growth and psychomotor development were normal, but ultrasound examination still revealed a dense renal parenchyma. Partial HPRT deficiency is a newly recognised treatable form of renal failure in the newborn.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"751-5"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15103830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Filtration fraction: an index of renal disease activity in patients with systemic lupus erythematosus. 滤过分数:系统性红斑狼疮患者肾脏疾病活动性的指标。
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress Pub Date : 1985-01-01
H Favre, P A Miescher
{"title":"Filtration fraction: an index of renal disease activity in patients with systemic lupus erythematosus.","authors":"H Favre,&nbsp;P A Miescher","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Renal plasma flow (RPF) and glomerular filtration rate (GFR) were estimated by 125I hippuran and 51Cr EDTA clearances using a single shot technique on two occasions at one-year intervals in 22 patients fulfilling the ARA criteria for systemic lupus erythematosus (SLE). All these patients had histologically proven renal disease. Filtration fraction was a better parameter than proteinuria, urinary sediment or GFR for recognising diffuse proliferative glomerulonephritis with a sensitivity of 61 per cent and a specificity of 88 per cent. After one year all the patients with an initially low filtration fraction (FF) had significantly changed their GFR, which demonstrates that this parameter indicates the presence of an active renal lesion.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"717-21"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15103950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the intact hormone assay in the study of parathyroid autograft function. 完整激素测定法在自体甲状旁腺移植功能研究中的评价。
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress Pub Date : 1985-01-01
E C Wijeyesinghe, A J Parnham, J R Farndon, R Wilkinson
{"title":"Evaluation of the intact hormone assay in the study of parathyroid autograft function.","authors":"E C Wijeyesinghe,&nbsp;A J Parnham,&nbsp;J R Farndon,&nbsp;R Wilkinson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Parathyroid autograft function was studied using radioimmunoassay measuring intact parathormone (iPTH) and C-terminal PTH (C-PTH). Blood samples were taken from graft and non-graft arms pre- and post-dialysis. The intact assay showed an appreciably greater differential gradient pre- and post-dialysis than the C-terminal assay. We conclude that particularly in patients with chronic renal failure the intact assay is of greater value in monitoring graft function than the commonly used C-terminal assay. It may also be of value in distinguishing between graft overactivity and ectopic cervical parathyroid tissue in cases of recurrent hyperparathyroidism following apparently total parathyroidectomy and autotransplantation.</p>","PeriodicalId":77886,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress","volume":"21 ","pages":"426-30"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15105007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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