Bone scan in haemodialysis patients: relation to hyperparathyroidism and aluminium toxicity.

Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress Pub Date : 1985-01-01

C Tielemans, R Wens, F Collart, M Dratwa, J Smeyers-Verbeke, I Van Hooff, G De Roy, P Bergmann, D Verbeelen

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Abstract

The influence of hyperparathyroidism and aluminium toxicity on bone scan scores (FS = Fogelman's score) was studied in 37 haemodialysis patients (group 1), of whom 24 had aluminium toxicity (group 2). FS, parathormone (iPTH) and aluminium status were assessed simultaneously, the latter by measuring serum aluminium before (BAl) and 48 hours after (PAl) a desferrioxamine infusion. FS correlated directly with iPTH in all groups, inversely with PAl and DAl (= PAl - BAl) in group 1; FS less than or equal to 2 was found in group 2 only (2 alpha less than 0.05). The time course of FS and aluminium concentration was also studied in 24 patients: a PAl increase was significantly associated with a FS decrease (2 alpha less than 0.001). In conclusion, hyperparathyroidism increases and aluminium toxicity decreases FS; FS less than or equal to 2 is very suggestive of aluminium toxicity.

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血液透析患者的骨扫描:与甲状旁腺功能亢进和铝中毒的关系。

研究了甲状旁腺功能亢进和铝毒性对37例血液透析患者(1组)骨扫描评分(FS = Fogelman评分)的影响，其中24例有铝毒性(2组)。同时评估FS、甲状旁腺激素(iPTH)和铝状态，后者通过输注去铁胺前(BAl)和输注后48小时(PAl)测定血清铝。各组FS与iPTH呈正相关，与PAl、DAl呈负相关(= PAl - BAl);只有2组FS小于等于2 (2 α < 0.05)。还研究了24例患者的FS和铝浓度的时间过程:PAl升高与FS降低显著相关(2 α < 0.001)。综上所述，甲状旁腺功能亢进增加，铝毒性降低;FS小于或等于2，说明铝有毒性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress

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