Anais brasileiros de dermatologia最新文献

{"title":"Solitary verrucous plaque on the chin: hypertrophic discoid lupus erythematosus⋆","authors":"Carolina Viza Amorim, Maria de Lourdes Bialon Santana, Maria Leticia Cintra, Fernanda Teixeira","doi":"10.1016/j.abd.2024.06.005","DOIUrl":"10.1016/j.abd.2024.06.005","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 374-376"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and epidemiological characterization of patients with cutaneous tuberculosis treated at a referral center in the Brazilian Amazon: case series","authors":"Letícia Rezende da Silva Sobral ,&nbsp;Isabela de Nazaré Tavares Cardoso Souza ,&nbsp;Maria Fernanda de Almeida Cavalcante Aranha ,&nbsp;Ana Beatriz Dias Silva ,&nbsp;Maria Amélia Lopes dos Santos ,&nbsp;Renata Mie Oyama Okajima ,&nbsp;Francisca Regina Oliveira Carneiro ,&nbsp;Carla Andréa Avelar Pires","doi":"10.1016/j.abd.2024.05.007","DOIUrl":"10.1016/j.abd.2024.05.007","url":null,"abstract":"<div><h3>Background</h3><div>Cutaneous tuberculosis is a rare form of the disease that defies diagnosis due to the diversity of clinical presentations. This study was based on the reality of a dermatology referral center in the Brazilian Amazon region to detail several characteristics of this disease.</div></div><div><h3>Objective</h3><div>To describe a series of cases of cutaneous tuberculosis treated at a dermatology service in the Brazilian Amazon region, addressing epidemiological aspects, clinical forms, diagnostic methods, treatment, and outcomes.</div></div><div><h3>Methods</h3><div>This is a descriptive and observational study of the case series type, including eight patients with a confirmed diagnosis of cutaneous tuberculosis seen between 2021 and 2023. A standardized protocol was used to collect data from patients' medical records.</div></div><div><h3>Results</h3><div>Among the eight cases of cutaneous tuberculosis, there were four cases of erythema induratum of Bazin, one case of tuberculosis verrucosa cutis, two cases of scrofuloderma, and one case of lupus vulgaris. Erythema induratum of Bazin, the most common form in the study, occurred predominantly in women, presenting as infiltrated plaques and erythematous nodules. All eight cases were treated with the standard therapeutic regimen of the Brazilian Ministry of Health (rifampicin, isoniazid, pyrazinamide, and ethambutol).</div></div><div><h3>Study limitations</h3><div>They include the small sample size, making generalizations difficult.</div></div><div><h3>Conclusions</h3><div>The study addressed the clinical diversity of cutaneous tuberculosis, with erythema induratum of Bazin as the most common form. The importance of the socioeconomic context in the prevalence of the disease and the need for more comprehensive epidemiological studies to improve the understanding of cutaneous tuberculosis, especially in endemic regions, are highlighted.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 228-236"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zosteriform cutaneous metastases of HER-2 positive breast carcinoma resolved after treatment with lapatinib","authors":"Marcela Hernández-Coronado,&nbsp;Iván Alejandro Rivera-Alonso,&nbsp;Adrian Cuellar-Barboza,&nbsp;Jorge Ocampo-Candiani","doi":"10.1016/j.abd.2024.07.012","DOIUrl":"10.1016/j.abd.2024.07.012","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 403-406"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Representation of images of black skin in pediatric textbooks","authors":"Maria Eduarda Duarte de Oliveira,&nbsp;Ronald Godinho de Oliveira Silva,&nbsp;Melissa Moreira Mansur Clemente,&nbsp;Sabrine Teixeira Ferraz Grunewald","doi":"10.1016/j.abd.2024.07.006","DOIUrl":"10.1016/j.abd.2024.07.006","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 346-349"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"II Consensus of the Brazilian Society of Dermatology for the treatment of alopecia areata","authors":"Paulo Müller Ramos ,&nbsp;Alessandra Anzai ,&nbsp;Bruna Duque-Estrada ,&nbsp;Daniel Fernandes Melo ,&nbsp;Flavia Sternberg ,&nbsp;Leopoldo Duailibe Nogueira Santos ,&nbsp;Lorena Dourado Alves ,&nbsp;Fabiane Mulinari-Brenner","doi":"10.1016/j.abd.2024.10.001","DOIUrl":"10.1016/j.abd.2024.10.001","url":null,"abstract":"<div><h3>Background</h3><div>Alopecia areata is a highly frequent disease with great variability in clinical presentation, severity, and prognosis. It has a significant negative impact on quality of life, especially in the moderate and severe forms.</div></div><div><h3>Objective</h3><div>To disseminate guidelines, prepared by a group of Brazilian experts, for the treatment and follow-up of patients with alopecia areata.</div></div><div><h3>Methods</h3><div>Eight specialists from different university centers with experience in alopecia areata were appointed by the Brazilian Society of Dermatology to reach a consensus on its treatment. Using the adapted DELPHI methodology, relevant elements were considered and then an analysis of the recent literature was carried out and the text produced. Consensus on the guidelines was defined with the approval of at least 70% of the panel of experts.</div></div><div><h3>Results/Conclusions</h3><div>Treatments vary according to patient age and disease severity. Intralesional injectable corticosteroid therapy was considered the first option for localized disease in adults. In severe cases, Janus Kinase inhibitors are the treatment with the highest level of evidence. Systemic corticosteroid therapy and immunosuppressants (corticosteroid-sparing agents) are also options in these cases. Contact immunotherapy (diphencyprone) is an alternative for stable extensive cases. The assessment of side effects is as important as the hair regrowth rate.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 328-341"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interference of the positioning of nickel, chromium and cobalt in the results of patch tests","authors":"Ida Duarte ,&nbsp;Rosana Lazzarini ,&nbsp;Mariana Haffner ,&nbsp;Julia P. Silva","doi":"10.1016/j.abd.2024.03.016","DOIUrl":"10.1016/j.abd.2024.03.016","url":null,"abstract":"<div><h3>Background</h3><div>The positioning of substances, which are co-sensitizers and/or with a tendency to cross-react, is not considered in the technique when applying patch tests (PT).</div></div><div><h3>Objective</h3><div>To investigate the interference of the positioning of nickel (Ni), chromium (Cr) and cobalt (Co) in patch tests (PT) results, when applied close or distant from each other.</div></div><div><h3>Methods</h3><div>PT were performed in patients suspected of allergic contact dermatitis (ACD), using the standard battery (SB), with substances showing a tendency towards cross-react and co-sensitizers applied far apart, and an additional battery (AB) with the metals placed close to each other. For tabulation purposes, only the 96-h reading was considered.</div></div><div><h3>Results</h3><div>Of the 86 tested patients, 33 (38%) had negative testing for metals and 53 (62%) had one or more positive (+) tests for Ni, Cr and/or Co. Concordant results in both tests (SB/ AB) occurred in 18/53 (34%) and 35/53 (66%) had discordant results. Regarding the SB, of the 159 tests with metals (53 patients, three metals), 57 tests were (+) and 102 (-). In the AB, 87 tests were (+) and 72 (-), a statistically significant difference (p &lt; 0.05). Of the 57 (+) tests in the SB, 35 were for Ni, 18 for Co and four for Cr. In AB the number of (+) tests was 87, with 45 (+) tests for Ni, 35 for Co and seven for Cr. The difference in the number of positive tests between the two batteries was statistically significant for Co and Ni.</div></div><div><h3>Study limitations</h3><div>The number of cases.</div></div><div><h3>Conclusion</h3><div>The results showed that the positioning of the metals interferes with the PT results and should be considered as part of the PT application technique.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 272-276"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142811936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dapsone-induced methemoglobinemia in a child with leprosy","authors":"John Verrinder Veasey ,&nbsp;Bruna Cavaleiro de Macedo Souza ,&nbsp;Guilherme Camargo Julio Valinoto","doi":"10.1016/j.abd.2024.05.006","DOIUrl":"10.1016/j.abd.2024.05.006","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 391-394"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Telemedicine (mobile-Health) as an alternative in the follow-up of patients in a randomized clinical trial for the treatment of cutaneous leishmaniasis in the state of Amazonas, Brazil","authors":"Silmara Navarro Pennini ,&nbsp;Jorge Augusto de Oliveira Guerra ,&nbsp;Paula Frassinetti Bessa Rebello ,&nbsp;Marília Rosa Abtibol-Bernardino ,&nbsp;Amanda Canto Duarte ,&nbsp;Higor Marques de Queiroz ,&nbsp;Anette Chrusciak-Talhari ,&nbsp;Maria das Graças Vale Barbosa Guerra ,&nbsp;Sinésio Talhari","doi":"10.1016/j.abd.2024.08.003","DOIUrl":"10.1016/j.abd.2024.08.003","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 355-357"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cytokines, chemokines and growth factors involved in keloids pathogenesis","authors":"Mengguo Liu","doi":"10.1016/j.abd.2024.01.010","DOIUrl":"10.1016/j.abd.2024.01.010","url":null,"abstract":"<div><div>Keloid is a common fibrotic disease, which is difficult to treat. It often causes itching and pain, which greatly disturbs patients in their work and daily life and causing difficulties in social interaction. Its pathogenesis is not clear, but may be related to several aspects: genetic susceptibility, environmental, immunological and endocrine factors, trauma and tension. The central point of its pathogenesis is the excessive proliferation of fibroblasts, with excessive synthesis and secretion of extracellular matrix such as collagen. However, the cause of fibroblast excessive proliferation and differentiation is not clear. Immune abnormalities may play an important role, with cytokines, chemokines, growth factors, and other important immune molecules acting on fibroblasts. This paper presents a detailed and comprehensive literature review on this subject.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 300-307"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Should patients undergoing hematopoietic stem cell transplantation undergo screening and monitoring for skin cancer?","authors":"Miguel Mansilla-Polo","doi":"10.1016/j.abd.2024.06.007","DOIUrl":"10.1016/j.abd.2024.06.007","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 372-373"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}