Anais brasileiros de dermatologia最新文献

{"title":"Extradigital glomus tumor in the deltopectoral region","authors":"Mauricio Sandoval Osses, Karol Baksai Elespuru, Camila Tais Escobar Soto, Diego San Martín Morandé","doi":"10.1016/j.abd.2026.501407","DOIUrl":"10.1016/j.abd.2026.501407","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 4","pages":"Article 501407"},"PeriodicalIF":4.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148300625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between invasion front and survival of patients with cutaneous melanomas","authors":"Vinícius Marinho Carvalho, Leonardo Emílio Sátiro Bezerra, Francisco Alves Moraes Neto, Juliana Polizel Ocanha-Xavier, Marcel Arakaki Asato, José Cândido Caldeira Xavier-Júnior","doi":"10.1016/j.abd.2026.501409","DOIUrl":"10.1016/j.abd.2026.501409","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 4","pages":"Article 501409"},"PeriodicalIF":4.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148381480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The skin microbiome: from historical ecology to therapeutic frontiers","authors":"Sabri Saeed Sanabani","doi":"10.1016/j.abd.2026.501393","DOIUrl":"10.1016/j.abd.2026.501393","url":null,"abstract":"<div><h3>Background</h3><div>Human skin, the body's largest organ, hosts a diverse ecosystem of bacteria, fungi, viruses, and mites collectively known as the skin microbiome. This microbiome supports cutaneous homeostasis through barrier defense, immune education, and metabolic functions.</div></div><div><h3>Objective</h3><div>To narratively review the historical evolution of skin microbiome research, synthesize current knowledge on its composition, biogeography, and functional roles in health and disease, and highlight emerging microbiome-based therapeutic strategies in dermatology.</div></div><div><h3>Methods</h3><div>This review integrates seminal historical works with contemporary evidence from culture-independent sequencing and multi-omic investigations of the skin microbiome, identified through a selective search of recent dermatology and microbiome literature.</div></div><div><h3>Results</h3><div>Modern molecular and multi-omic approaches have revealed microbial diversity across sebaceous, moist, and dry skin niches and clarified key functions of the skin microbiome, including colonization resistance, immune modulation, metabolite production, and participation in the gut-skin axis. Dysbiosis of these communities is linked to inflammatory conditions such as atopic dermatitis, acne vulgaris, psoriasis, and chronic wounds. A growing body of work supports microbiome-targeted interventions, including probiotics, prebiotics, postbiotics, and microbiome engineering, as promising personalized strategies.</div></div><div><h3>Study limitations</h3><div>As a narrative review, this work may be subject to selection bias and does not provide a quantitative synthesis of all available studies on the skin microbiome.</div></div><div><h3>Conclusions</h3><div>By integrating historical context with mechanistic insights from modern microbiome research, this review underscores the skin microbiome as a central ecological determinant of cutaneous health and disease and provides a framework for translating microbiome science into clinical applications and precision dermatology.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 4","pages":"Article 501393"},"PeriodicalIF":4.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148337313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Upadacitinib therapy for foreign body granuloma induced by facial fillers","authors":"Mengying Duan,&nbsp;Yi Wu,&nbsp;Hong Shen,&nbsp;Yeqin Dai","doi":"10.1016/j.abd.2026.501375","DOIUrl":"10.1016/j.abd.2026.501375","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 4","pages":"Article 501375"},"PeriodicalIF":4.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148262829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Palmoplantar Psoriasis Quality of Life Index into Brazilian Portuguese (PPQLI-BRA) ‒ Translation, cultural adaptation, and validation","authors":"Paula Hitomi Sakiyama,&nbsp;Caio Cesar Silva de Castro,&nbsp;Helena Zenedin Marchioro,&nbsp;Hélio Amante Miot","doi":"10.1016/j.abd.2026.501399","DOIUrl":"10.1016/j.abd.2026.501399","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 4","pages":"Article 501399"},"PeriodicalIF":4.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148325083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor-like periungual cutaneous sporotrichosis in an endemic area","authors":"Mathias Ferreira,&nbsp;Thiago Vilas Boas,&nbsp;Kananda Kesye Sousa Nunes,&nbsp;Guilherme Caldas de Souza,&nbsp;Carolina Talhari","doi":"10.1016/j.abd.2026.501397","DOIUrl":"10.1016/j.abd.2026.501397","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 4","pages":"Article 501397"},"PeriodicalIF":4.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148358947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complementary strategies in Psoriasis – non-pharmacological approaches for comprehensive management","authors":"Fernando Valenzuela ,&nbsp;Eine Benavides ,&nbsp;Esther Verónica Echeverry ,&nbsp;Dan Hartmann ,&nbsp;Daniza Bilicic","doi":"10.1016/j.abd.2026.501356","DOIUrl":"10.1016/j.abd.2026.501356","url":null,"abstract":"<div><h3>Background</h3><div>Psoriasis is a chronic immune-mediated inflammatory disease linked to systemic comorbidities such as obesity, diabetes, cardiovascular disease, and inflammatory bowel disease. Non-pharmacological interventions, such as dietary modifications, nutritional supplementation, exercise, and psychological interventions, have emerged as complementary therapies in the management of psoriasis.</div></div><div><h3>Objectives</h3><div>Review the current and recent evidence and the role of trace elements, vitamins, diet, exercise, and psychological interventions as complementary approaches in the management of patients with psoriasis.</div></div><div><h3>Materials and methods</h3><div>A narrative review was conducted, analyzing clinical trials, meta-analyses, and cohort studies from major databases.</div></div><div><h3>Results</h3><div>Trace elements such as zinc, copper, and selenium, and vitamins including D, E, B-complex, and A, play roles in oxidative stress modulation, immune regulation, and keratinocyte biology. However, the clinical efficacy of micronutrient supplementation remains uncertain due to inconsistent and conflicting findings. Dietary interventions, particularly Mediterranean diet adherence and weight loss through caloric restriction or bariatric surgery, have been associated with reductions in psoriasis severity, although clear clinical protocols are lacking. Aerobic exercise appears beneficial but is underutilized, partially due to psychological and disease-related barriers. Furthermore, psoriasis is associated with a high prevalence of psychological disorders, with the necessity to integrate psychological interventions to optimize disease management.</div></div><div><h3>Study limitations</h3><div>The available evidence is limited and with heterogeneity in study design, with small sample sizes, observational methodologies, and inconsistent intervention protocols, restricting causal inference and generalizability.</div></div><div><h3>Conclusion</h3><div>While non-pharmacological strategies show promise as complementary interventions in psoriasis management, they cannot replace conventional therapy. Further studies are required to confirm their clinical impact. These approaches should be considered as complementary strategies, with individualized patient assessments and continuous follow-up being essential.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 3","pages":"Article 501356"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147799430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of tofacitinib in the treatment of refractory palmoplantar psoriasis (non-pustular): case report and literature review","authors":"Paula Hitomi Sakiyama ,&nbsp;Luciane Donida Bartoli Miot ,&nbsp;Hélio Amante Miot","doi":"10.1016/j.abd.2026.501357","DOIUrl":"10.1016/j.abd.2026.501357","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 3","pages":"Article 501357"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147873093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psoriasiform adult blaschkitis triggered by adalimumab: a rare paradoxical reaction","authors":"Hiram Larangeira de Almeida Jr. ,&nbsp;Martina Souilljee Birck ,&nbsp;Laura Marcon Bischoff Bialecki ,&nbsp;Aline Paganelli ,&nbsp;Luísa Becker Martini ,&nbsp;Rodrigo Pereira Duquia","doi":"10.1016/j.abd.2026.501361","DOIUrl":"10.1016/j.abd.2026.501361","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 3","pages":"Article 501361"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147925592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spitz nevus in a patient with oculocutaneous albinism: dermoscopic and histopathologic correlation","authors":"Julia Aires Thomaz Maya ,&nbsp;Priscila Ishioka ,&nbsp;Leonardo Romaniello Gama de Oliveira ,&nbsp;Carolina Reato Marçon","doi":"10.1016/j.abd.2026.501360","DOIUrl":"10.1016/j.abd.2026.501360","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 3","pages":"Article 501360"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147939615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}