Anais brasileiros de dermatologia最新文献

{"title":"Randomized, double-blind pilot study on botulinum toxin type A in the treatment of axillary hidradenitis suppurativa","authors":"Jessica Shen Tsy Wu Kim, Kevin Yun Kim, Laís de Abreu Mutti, Fernanda de Carvalho Tironi, Anamaria da Silva Facina, Samira Yarak, Sergio Henrique Hirata","doi":"10.1016/j.abd.2026.501461","DOIUrl":"10.1016/j.abd.2026.501461","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 5","pages":"Article 501461"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pro-oncogenic immunohistochemical markers in Merkel cell carcinoma with or without polyomavirus signature: a Brazilian cohort","authors":"Aline Siqueira Talarico, Murilo de Oliveira Lima Carapeba, Claudio de Lelis Filgueiras de Souza, Alexandre Ozores Michalany, Thiago Jeunon de Sousa Vargas, Gustavo Gonçalves Engelman, Rute Facchini Lellis, Rafael Fantelli Stelini, Julio Cesar Moraes, Fernanda Caramella Pereira, Isabel Cristina Gomes Moura, Daniela Cristina Gonçalves, Adilson Da Costa","doi":"10.1016/j.abd.2026.501438","DOIUrl":"10.1016/j.abd.2026.501438","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 5","pages":"Article 501438"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “Risk factors associated with chronic cutaneous graft-versus-host disease following hematopoietic stem cell transplantation: a pediatric cohort” – Reply","authors":"Daniela Carvajal, Teresa Dossi, Camila Downey, Daniela Krämer, Natalia González, Javier Fernández, Paula Muñoz","doi":"10.1016/j.abd.2026.501459","DOIUrl":"10.1016/j.abd.2026.501459","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 5","pages":"Article 501459"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Upadacitinib for refractory cutaneous disease in a patient with tif1γ-positive dermatomyositis","authors":"Yusuf Demir, Hande Ogun, Bercemhan Sulu, Muazzez Cigdem Oba, Emire Seyahi","doi":"10.1016/j.abd.2026.501443","DOIUrl":"10.1016/j.abd.2026.501443","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 5","pages":"Article 501443"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful treatment of coexisting alopecia areata and hidradenitis suppurativa with upadacitinib","authors":"Patrícia Moreira Gomes, Ruben Costa, Ana Pedrosa, Carmen Lisboa","doi":"10.1016/j.abd.2026.501453","DOIUrl":"10.1016/j.abd.2026.501453","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 5","pages":"Article 501453"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148863089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative clinical and sociodemographic analysis of well-differentiated squamous cell carcinoma and keratoacanthoma in kidney transplant recipients and immunocompetent individuals","authors":"Camila Santos Lopes, Lara Araújo Dias, Sergio Henrique Hirata, Milvia Maria Simões e Silva Enokihara, Heron Fernando de Sousa Gonzaga, Jane Tomimori","doi":"10.1016/j.abd.2026.501452","DOIUrl":"10.1016/j.abd.2026.501452","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 5","pages":"Article 501452"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION to “What is your diagnosis? CLOVES syndrome” An Bras Dermatol. 2016;91(3):378-80","authors":"Manuela Panteliades,&nbsp;Claudia Marcia Resende Silva,&nbsp;Bernardo Gontijo","doi":"10.1016/j.abd.2026.501462","DOIUrl":"10.1016/j.abd.2026.501462","url":null,"abstract":"<div><div>This article has been removed: please see Elsevier Policy on Article Withdrawal (<span><span>https://www.elsevier.com/about/policies/article-withdrawal</span><svg><path></path></svg></span>).</div><div>The Editorial Team of <em>Anais Brasileiros de Dermatologia</em> has requested the removal of this article for legal reasons.</div></div><div>This article has been removed: please see Elsevier Policy on Article Withdrawal (<span><span>https://www.elsevier.com/about/policies/article-withdrawal</span><svg><path></path></svg></span>).</div><div>The Editorial Team of <em>Anais Brasileiros de Dermatologia</em> has requested the removal of this article for legal reasons.</div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 5","pages":"Article 501462"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149073301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapy-associated facial redness in atopic dermatitis: insights from a case series","authors":"Karol Sabas-Ortega,&nbsp;Sergio García-González,&nbsp;Mariano Ara-Martín,&nbsp;Ana Luisa Morales-Moya,&nbsp;Sonia de la Fuente Meira,&nbsp;Elena Bularca,&nbsp;Pablo Villagrasa-Boli,&nbsp;Luis Martinez-Lostao,&nbsp;Ignacio Rivera-Fuertes,&nbsp;Lucía Prieto-Torres","doi":"10.1016/j.abd.2026.501398","DOIUrl":"10.1016/j.abd.2026.501398","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 4","pages":"Article 501398"},"PeriodicalIF":4.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148300688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanocarriers for topical minoxidil in androgenetic alopecia: systematic review of preclinical and clinical evidence","authors":"Heloisa da Rocha Picado Copesco,&nbsp;Gustavo Sartori Albertino,&nbsp;Filipe Rocha Lima,&nbsp;Antonio Claudio Tedesco,&nbsp;Marco Andrey Cipriani Frade","doi":"10.1016/j.abd.2026.501400","DOIUrl":"10.1016/j.abd.2026.501400","url":null,"abstract":"<div><h3>Background</h3><div>Androgenetic Alopecia (AGA) is the most prevalent hair disorder. Conventional topical minoxidil is limited by suboptimal follicular penetration, local adverse effects, and poor adherence; nanocarrier-based “nanominoxidil” systems may optimize delivery, but their clinical value remains uncertain.</div></div><div><h3>Objective</h3><div>To synthesize experimental and clinical evidence on nanocarrier-based topical minoxidil for AGA.</div></div><div><h3>Methods</h3><div>We systematically searched databases (2015–2024) for <em>in vitro</em>, <em>ex-vivo</em>, <em>in vivo</em>, and human studies evaluating nanocarriers &lt; 1000 nm loaded with minoxidil versus conventional minoxidil, placebo, or no treatment. Primary outcomes were follicular and cutaneous penetration or retention; secondary outcomes included hair length, density and/or coverage, biomarker modulation, adverse events, and formulation stability. Risk of bias was assessed with SYRCLE and OHAT.</div></div><div><h3>Results</h3><div>Of 410 records, 20 studies met eligibility criteria, predominantly preclinical, and one evaluated cutaneous tolerability in healthy volunteers. Across platforms (lipid, polymeric, hybrid and deformable systems, nanoemulsions), nanominoxidil consistently increased follicular deposition and cutaneous retention (≈2- to &gt; 7-fold vs conventional solutions) and improved hair growth surrogates and angiogenic or stem-cell markers. Local tolerability was generally acceptable and systemic exposure was negligible when reported.</div></div><div><h3>Study limitations</h3><div>Evidence is preclinical, with a single non-therapeutic human study; heterogeneity across models, comparators, doses, follow-up, and outcomes, and frequent lack of randomization, blinding, and standardized safety reporting, precluded meta-analysis and limited internal validity and generalizability.</div></div><div><h3>Conclusions</h3><div>Nanotechnology-based minoxidil formulations enhance follicular targeting and hair-growth surrogate outcomes in experimental models and appear locally safe, but randomized trials in patients with AGA are required before nanominoxidil can be recommended for routine clinical use.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 4","pages":"Article 501400"},"PeriodicalIF":4.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148381448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral white sponge nevus in patients with ectrodactyly-ectodermal dysplasia-cleft syndrome: two patients treated with liquid nitrogen cryotherapy","authors":"Paula Gerlero,&nbsp;Silvia Vanessa Lourenço,&nbsp;Marcello Menta Simonsen Nico","doi":"10.1016/j.abd.2026.501401","DOIUrl":"10.1016/j.abd.2026.501401","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 4","pages":"Article 501401"},"PeriodicalIF":4.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148270057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}