巴西一项多中心研究：酒渣鼻患者的临床人口学特征、加重因素、合并症和生活质量（GBPER：巴西酒渣鼻研究小组）

IF 3.6 4区医学 Q2 DERMATOLOGY

Anais brasileiros de dermatologia Pub Date : 2025-07-11 DOI:10.1016/j.abd.2025.501160

Renan Rangel Bonamigo , Paula Barea , Juliano Peruzzo , Juliana Boza , Hélio Amante Miot , Edileia Bagatin , Luiz Maurício Costa Almeida , Giovanni Indelicato Milano , Carla Wanderley Gayoso de Lima , Linácia Freitas Vidal , Fabíola Rosa Picosse , Bruna Manuella de Figueiredo Afonso , Clivia Maria Moraes de Oliveira

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引用次数: 0

摘要

背景：痤疮是最常见的面部慢性血管炎性皮肤病。其发病机制包括遗传和环境因素、神经血管改变和先天免疫。许多诱发和加重因素以及全身性合并症与该病有关，但在巴西对其流行病学的研究很少。目的描述在转诊中心治疗的酒渣鼻患者的概况，并调查合并症、饮食方面、恶化因素和生活质量的存在。方法巴西横断面多中心研究。评估临床和人口统计数据、疾病严重程度、触发和/或加重因素、饮食、合并症和对生活质量的影响。结果共纳入258例患者，年龄35 ~ 65岁，以女性为主。89%的病例的临床表现从轻度到中度不等，58%的病例的生活质量受到合理到轻微的影响。96%的患者报告了酒渣鼻的加重因素，其中气候暴露、酒精饮料和情绪变化是最常见的。在被提及为加重因素的食物中（28%），辣椒、其他调味品和热饮是最常见的。89%的参与者报告了合并症，重点是内分泌（48%）、精神（35%）、心血管（31%）和胃肠道（28%）疾病。研究限制：非对照研究，包括接受皮肤科治疗的患者。结论：本研究证实了巴西酒渣鼻患者的特征与文献中描述的一致，该疾病存在于较高的光型是相关的。辣椒等调味品和热饮是重要的加重因素，大多数患者报告存在各种合并症。

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Clinical-demographic profile, aggravating factors, comorbidities, and quality of life in patients with Rosacea: a Brazilian multicenter study (GBPER: Brazilian Research and Studies Group on Rosacea)

Background

Rosacea is the most prevalent chronic vascular-inflammatory dermatosis of the face. Its pathogenesis includes genetic and environmental factors, neurovascular alterations, and innate immunity. Many triggering and aggravating factors, as well as systemic comorbidities, have been associated with the disease, but there are few studies on its epidemiology in Brazil.

Objectives

To describe the profile of patients with rosacea treated at referral centers, as well as to investigate the presence of comorbidities, dietary aspects, worsening factors, and quality of life.

Methods

Cross-sectional and multicenter Brazilian study. Clinical and demographic data, disease severity, triggering and/or aggravating factors, diet, comorbidities, and impact on quality of life were evaluated.

Results

258 patients were included, predominantly women, between 35 and 65 years old and phototypes III, IV and II. The clinical picture ranged from mild to moderate in 89% of cases and quality of life was reasonable to slightly affected in 58% of cases. Aggravating factors for rosacea were reported by 96% of patients, with climate exposure, alcoholic beverages, and emotional changes being the most frequent. Among the foods mentioned as aggravating factors (28%), pepper, other condiments and hot beverages were the most frequently reported. Comorbidities were reported by 89% of the participants, with emphasis on endocrine (48%), psychiatric (35%), cardiovascular (31%) and gastrointestinal (28%) diseases.

Study limitations

Uncontrolled study, including patients undergoing dermatological treatment.

Conclusions

This study establishes that the profile of Brazilian patients with rosacea corroborates that described in the literature, with the presence of the disease in higher phototypes being relevant. Pepper and other condiments and hot beverages were important aggravating factors, and the presence of various comorbidities was reported by most of the patients.

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来源期刊

Anais brasileiros de dermatologia DERMATOLOGY-

CiteScore

2.40

自引率

0.00%

发文量

184

审稿时长

32 days

期刊介绍： The journal is published bimonthly and is devoted to the dissemination of original, unpublished technical-scientific study, resulting from research or reviews of dermatological topics and related matters. Exchanges with other publications may be accepted.