Carlos Baena-Palomino, Ana Castellano-Martínez, Moisés Rodríguez-González
{"title":"Uso de inhibidores del cotransportador de sodio-glucosa tipo 2 (iSGLT2) en tres adolescentes con insuficiencia cardiaca por miocardiopatía hipertrófica no obstructiva","authors":"Carlos Baena-Palomino, Ana Castellano-Martínez, Moisés Rodríguez-González","doi":"10.1016/j.anpedi.2025.503802","DOIUrl":"10.1016/j.anpedi.2025.503802","url":null,"abstract":"","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 6","pages":"Article 503802"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Johanna Ramírez-Romero, Claudia Cifuentes, Beatriz Azkunaga, Santiago Mintegi, Grupo de Trabajo de Intoxicaciones de la Sociedad Española de Urgencias Pediátricas
{"title":"Intoxicaciones por errores de dosificación de fármacos en España","authors":"Johanna Ramírez-Romero, Claudia Cifuentes, Beatriz Azkunaga, Santiago Mintegi, Grupo de Trabajo de Intoxicaciones de la Sociedad Española de Urgencias Pediátricas","doi":"10.1016/j.anpedi.2025.503888","DOIUrl":"10.1016/j.anpedi.2025.503888","url":null,"abstract":"<div><h3>Introduction</h3><div>Dosage errors are a common mechanism of poisoning in childhood. The aim of this study was to analyze the characteristics and management of poisoning secondary to dosage errors in pediatric emergency departments (EDs) in Spain.</div></div><div><h3>Methodology</h3><div>Study based on a prospective register of poisonings documented in 58 Spanish EDs participating in the Toxicology Surveillance Observatory of the Spanish Society of Paediatric Emergency Medicine (SEUP) between 2008 and 2023.</div></div><div><h3>Results</h3><div>The register documented 3429 episodes of exposure to toxic substances, of which 289 (8.4%) were medication dosing errors, with a vast majority occurring in the home setting. Seventy-eight (27.0%) occurred in children aged less than 1 year (amounting to 37.9% of poisonings in this age group and 85.0% of poisonings in infants aged less than 3 months). Overall, the most commonly involved medications were antipyretics/analgesics (35.6%, mainly paracetamol), with significant differences depending on patient age. Forty-nine of the patients (17.0%) were symptomatic, 118 (41.8%) underwent additional testing, 83 (28.7%) received treatment, and 115 (39.8%) were admitted to the ED observation unit or to hospital. All had favorable outcomes.</div></div><div><h3>Conclusions</h3><div>Medication dosing errors constitute an important mechanism of poisoning, especially in children aged less than 1 year, leading to a significant number of interventions in EDs. Preventive measures aimed at educating families to avoid these poisonings should be considered.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 6","pages":"Article 503888"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gerard Martínez-Segura , Silvia Rodríguez Ferradas , Cristina Macias Borras , Victoria Trenchs Sainz de la Maza , Ana Isabel Curcoy Barcenilla
{"title":"Sospecha de maltrato en urgencias: adecuación del tipo de consultas","authors":"Gerard Martínez-Segura , Silvia Rodríguez Ferradas , Cristina Macias Borras , Victoria Trenchs Sainz de la Maza , Ana Isabel Curcoy Barcenilla","doi":"10.1016/j.anpedi.2025.503808","DOIUrl":"10.1016/j.anpedi.2025.503808","url":null,"abstract":"","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 6","pages":"Article 503808"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Histiocitosis de células de Langerhans: imagen de un caso","authors":"Lidia Galán Cotelo, Tania Penas Iglesias, Natalian Mandiá Rodríguez, Alejandro Pérez Muñuzuri","doi":"10.1016/j.anpedi.2025.503780","DOIUrl":"10.1016/j.anpedi.2025.503780","url":null,"abstract":"","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 6","pages":"Article 503780"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reyes Fernández Montes , María Agustina Alonso Álvarez , María Fernández Miaja , Luis Vega López , María Álvarez Merino , Estíbaliz Garrido García
{"title":"Plasmalyte vs. suero fisiológico para rehidratación rápida en gastroenteritis: estudio observacional prospectivo","authors":"Reyes Fernández Montes , María Agustina Alonso Álvarez , María Fernández Miaja , Luis Vega López , María Álvarez Merino , Estíbaliz Garrido García","doi":"10.1016/j.anpedi.2025.503855","DOIUrl":"10.1016/j.anpedi.2025.503855","url":null,"abstract":"<div><h3>Introduction</h3><div>General recommendations suggest using physiological saline solution (PSS) in the guidelines for rapid intravenous rehydration (RIR) in children with dehydration secondary to acute gastroenteritis, although the use of a balanced crystalloid solution, such as Plasmalyte (PLA), could be more beneficial since its composition is more similar to plasma.</div></div><div><h3>Materials and Methods</h3><div>Single-center prospective and observational study with two treatment groups. The sample consisted of patients aged 3 months to 13 years with mild to moderate dehydration in whom RIR was indicated based on the SEUP guideline, who visited the pediatric emergency department (PED) of a tertiary care hospital. A total of 40<!--> <!-->mL/kg of solution (PLA or PSS, at the discretion of the physician in charge) supplemented with 2.5% glucose was administered over 2<!--> <!-->hours. We collected data on clinical and laboratory variables before and after RIR, length of stay, need for readmission and adverse events.</div></div><div><h3>Results</h3><div>A total of 169 patients (50.9% male; median age, 40 months) completed the study. Of these, 49.1% received PLA. The group that received PLA showed greater improvement in bicarbonate levels (3.7<!--> <!-->mmol/L vs 1.4<!--> <!-->mmol/L; <em>P</em> <!--><<!--> <!-->.001) and a lower increase in chloride levels (0.9<!--> <!-->mmol/L vs 4.1<!--> <!-->mmol/L; <em>P</em> <!--><<!--> <!-->.001). There were no differences in clinical dehydration scales, length of stay in PED or need for readmission. No serious adverse events were observed.</div></div><div><h3>Conclusions</h3><div>The use of PLA in the RIR protocol was effective and safe, showing greater recovery of bicarbonate with lesser elevation of chloride levels compared to the use of PSS. However, we did not find differences in clinical outcomes.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 6","pages":"Article 503855"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Gonzalez Jiménez , Juan Rodríguez Delgado , Cristina Campoy , Rafael Galera Martínez , Mercedes Gil-Campos , Susana Redecillas Ferreiro , Miguel Sáenz de Pipaón , Rosaura Leis , en representación del Comité de Nutrición y Lactancia Materna de la AEP
{"title":"Suplementación con vitamina D en población pediátrica sana","authors":"David Gonzalez Jiménez , Juan Rodríguez Delgado , Cristina Campoy , Rafael Galera Martínez , Mercedes Gil-Campos , Susana Redecillas Ferreiro , Miguel Sáenz de Pipaón , Rosaura Leis , en representación del Comité de Nutrición y Lactancia Materna de la AEP","doi":"10.1016/j.anpedi.2025.503874","DOIUrl":"10.1016/j.anpedi.2025.503874","url":null,"abstract":"<div><h3>Objective</h3><div>To review the current scientific evidence on the efficacy of universal vitamin<!--> <!-->D supplementation in healthy children with no risk factors and to propose updated modifications to the recommendations provided in the main clinical practice guidelines.</div></div><div><h3>Methods</h3><div>Scoping review through a literature search conducted in PubMed for articles published in English or Spanish in the past 15<!--> <!-->years using the following MeSH search terms: (vitamin D) AND (supplementation). The search yielded 2133 articles, of which 22 were selected.</div></div><div><h3>Results</h3><div>In infants aged less than 1<!--> <!-->year without risk factors, administration of 400<!--> <!-->IU/day improves serum levels of calcifediol, but most studies have not found an association with improved bone health assessed by dual-energy X-ray absorptiometry. In children aged more than 1<!--> <!-->year with calcifediol levels of less than 35<!--> <!-->ng/mL, supplementation with 400 to 800<!--> <!-->IU/day of vitamin<!--> <!-->D decreases the risk of respiratory infection. There is still no evidence in the pediatric population that vitamin<!--> <!-->D supplementation either decreases the risk or severity of other infections or offers any other clinically significant extraskeletal benefits.</div></div><div><h3>Conclusion</h3><div>Based on the main clinical practice guidelines, supplementation with vitamin<!--> <!-->D at a dose of 400<!--> <!-->IU/day is recommended for breastfed infants aged less than 1<!--> <!-->year or infants who do not achieve the recommended daily intake through infant formula. In children aged more than 1<!--> <!-->year, supplementation should be individualized.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 6","pages":"Article 503874"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}