Lectura crítica (ii): aplicación en artículos científicos sobre intervenciones terapéuticas, revisiones sistemáticas y metanálisis

IF 2.1 4区医学 Q2 PEDIATRICS

Anales de pediatria Pub Date : 2025-10-01 DOI:10.1016/j.anpedi.2025.503891

Álvaro Gimeno Díaz de Atauri , María Salomé Albi Rodríguez , Elena Pérez González , Jaime Javier Cuervo Valdés , Juan Ruiz-Canela Cáceres , Javier González de Dios , Comité de Trabajo de Pediatría Basada en la Evidencia

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引用次数: 0

Abstract

In this article, we discuss the methodology for the critical appraisal of clinical trials and systematic reviews. Studies of either type, when well designed and executed, provide the best evidence for clinical decision-making. Clinical trials are the primary source of evidence for evaluating therapeutic interventions, and systematic reviews analyze and synthesize research of a certain quality to answer a specific clinical question. To assess their validity, it is essential that they aim to answer a specific question in terms of population, intervention and outcomes, and that the risk of bias is reduced as much as possible during their development, from design to publication. The article addresses the steps to take to assess whether a clinical trial or systematic review meets the criteria for its results to be considered reliable (valid). Once their validity is confirmed, the magnitude and clinical relevance of the results must be assessed, in addition to their applicability to our patients in particular.

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评论阅读（ii）：在关于治疗干预措施、系统综述和荟萃分析的科学论文中的应用

在这篇文章中，我们讨论了临床试验和系统评价的批判性评价方法。任何一种类型的研究，如果设计和执行得当，都能为临床决策提供最好的证据。临床试验是评价治疗干预措施的主要证据来源，系统评价是分析和综合一定质量的研究来回答特定的临床问题。为了评估它们的有效性，至关重要的是，它们的目标是回答一个特定的问题，包括人口、干预和结果，并且在它们的开发过程中，从设计到发表，偏见的风险尽可能地降低。本文讨论了评估临床试验或系统评价是否符合其结果被认为可靠（有效）的标准所采取的步骤。一旦它们的有效性得到确认，必须评估结果的大小和临床相关性，以及它们对我们患者的适用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Anales de pediatria 医学-小儿科

CiteScore

2.10

自引率

4.80%

发文量

155

审稿时长

44 days

期刊介绍： La Asociación Española de Pediatría tiene como uno de sus objetivos principales la difusión de información científica rigurosa y actualizada sobre las distintas áreas de la pediatría. Anales de Pediatría es el Órgano de Expresión Científica de la Asociación y constituye el vehículo a través del cual se comunican los asociados. Publica trabajos originales sobre investigación clínica en pediatría procedentes de España y países latinoamericanos, así como artículos de revisión elaborados por los mejores profesionales de cada especialidad, las comunicaciones del congreso anual y los libros de actas de la Asociación, y guías de actuación elaboradas por las diferentes Sociedades/Secciones Especializadas integradas en la Asociación Española de Pediatría.