Anales de pediatria最新文献_第2页

Sífilis congénita en aumento. Revisión de 5 años en un hospital de referencia en Portugal 先天性梅毒上升。葡萄牙转诊医院5年复查

IF 1.5 4区医学

Anales de pediatria Pub Date : 2025-05-01 DOI: 10.1016/j.anpedi.2025.503800

Sara Catarino , Lídia Carvalho , Angélica Ramos , Manuela Rodrigues , Ana Reis-Melo

引用次数: 0

Síndrome del pinzamiento posterior del tobillo 踝关节后捏综合症

IF 1.5 4区医学

Anales de pediatria Pub Date : 2025-05-01 DOI: 10.1016/j.anpedi.2024.503722

Oihane Salcedo Fresneda , Estibaliz Garrido García

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Flebolitos como marcador radiológico de malformación venosa 小静脉石作为静脉畸形的放射标志物

IF 1.5 4区医学

Anales de pediatria Pub Date : 2025-05-01 DOI: 10.1016/j.anpedi.2024.503748

Israel Pérez-López, Marta Cebolla-Verdugo, Ricardo Ruiz-Villaverde

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Herpes-zóster en un paciente vacunado recientemente de varicela 最近接种过水痘疫苗的患者的带状疱疹

IF 1.5 4区医学

Anales de pediatria Pub Date : 2025-05-01 DOI: 10.1016/j.anpedi.2024.503723

Omar Al-wattar-Ceballos, Marina Montero-García, Mónica Gómez-Manzanares, Carlos Mendoza-Chaparro

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Avances en el tratamiento de la fibrosis quística: los moduladores de la CFTR 囊性纤维化治疗的进展：CFTR调制器

IF 1.5 4区医学

Anales de pediatria Pub Date : 2025-05-01 DOI: 10.1016/j.anpedi.2025.503857

Maria Dolores Pastor-Vivero , Jordi Costa i Colomer , Carlos Martín de Vicente , Saioa Vicente-Santamaria , Ruth García Romero , David González Jiménez , Carmen Luna Paredes

{"title":"Avances en el tratamiento de la fibrosis quística: los moduladores de la CFTR","authors":"Maria Dolores Pastor-Vivero , Jordi Costa i Colomer , Carlos Martín de Vicente , Saioa Vicente-Santamaria , Ruth García Romero , David González Jiménez , Carmen Luna Paredes","doi":"10.1016/j.anpedi.2025.503857","DOIUrl":"10.1016/j.anpedi.2025.503857","url":null,"abstract":"<div><div>Cystic fibrosis is a severe genetic disease caused by variants in the <em>CFTR</em> gene. Although it is a multisystem disease, respiratory involvement is the main cause of morbidity and mortality. Cystic fibrosis transmembrane conductance regulator modulator (CFTRm) therapies have advanced the treatment of this disease by improving function of this protein. Ivacaftor, the first CFTRm, has been found to significantly improve lung function and quality of life in patients with certain gating variants. However, only a small percentage of patients in Spain are eligible for this treatment. Combinations of correctors and potentiators, such as lumacaftor-ivacaftor or tezacaftor-ivacaftor, have been developed for treatment of patients with the most frequent variant (F508del), although with limited benefits. Triple therapy with elexacaftor-tezacaftor-ivacaftor has been found to significantly improve respiratory, gastrointestinal and nutritional outcomes as well as quality of life, thus changing the management of CF in eligible patients. The impact of triple therapy is also reflected in an increase in life expectancy and a decrease in mortality and lung transplantation. As regards hepatic and pancreatic involvement, while CFTR modulators have exhibited promising effects, further research is required. The use of CFTR modulators has also shifted nutritional status trends in patients with CF, reducing the risk of undernutrition but increasing the risk of obesity. The use of these drugs for treatment of less frequent variants and for potential antenatal treatment is currently being investigated. Despite these advances, there is still a subset of patients who are ineligible for treatment with modulators or highly effective therapy.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503857"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consentimiento sexual en la adolescencia. Influencia del consumo de la «nueva pornografia» en la toma de decisiones 青少年时期的性同意。“新色情”消费对决策的影响

IF 1.5 4区医学

Anales de pediatria Pub Date : 2025-04-01 DOI: 10.1016/j.anpedi.2025.503791

Ester Barrios Miras , Montserrat Esquerda Areste

{"title":"Consentimiento sexual en la adolescencia. Influencia del consumo de la «nueva pornografia» en la toma de decisiones","authors":"Ester Barrios Miras , Montserrat Esquerda Areste","doi":"10.1016/j.anpedi.2025.503791","DOIUrl":"10.1016/j.anpedi.2025.503791","url":null,"abstract":"<div><div>Adolescence is a transitional stage of development, with imprecise age limits, during which the individual progressively develops the maturity required for decision-making. Sexual consent is part of the right to sexual freedom, a fundamental right that must be promoted and taught from childhood. At present, there is considerable social alarm in relation to the risks associated with the increased consumption of pornography from an early age. Pornography provides a distorted image of sexual relations that does not feature the elements of consent or respect to the other, commonly offering visual content that normalizes violence, humiliation and the objectification of human beings. The lack of comprehensive sex education with an affective component, combined with the emergence of “new pornograph” as a school of sexuality, means that adolescents may come to accept and/or normalize nonconsensual sexual relations that can violate the dignity of the individual. The aim of the study was to perform a critical review of the literature available in the main databases published from 2015 to present in order to characterize the consumption of pornography by adolescents and its associated risks. Lastly, it addresses individual and social factors involved in sexual consent, as well as aspects related to the autonomy required for the individual to be able to consent.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 4","pages":"Article 503791"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cuidados paliativos para pacientes pediátricos con cáncer en España: análisis de los recursos y barreras descritos 西班牙儿童癌症患者的姑息治疗：资源和障碍分析

IF 1.5 4区医学

Anales de pediatria Pub Date : 2025-04-01 DOI: 10.1016/j.anpedi.2025.503767

Iñigo de Noriega , Fátima Parra Plantagenet-Whyte , José Antonio Salinas , Gisela Michel , Eddy Carolina Pedraza

引用次数: 0

Somatizaciones en la infancia y en la adolescencia: una enfermedad en aumento 儿童和青少年躯体化：一种日益严重的疾病

IF 1.5 4区医学

Anales de pediatria Pub Date : 2025-04-01 DOI: 10.1016/j.anpedi.2025.503797

Raquel Martínez Lorenzo, Laura Otero Pérez, Laura Piñeiro Feal, Hector Alejandro Rodriguez Chitiva

引用次数: 0

Otoscopia digital en urgencias de pediatría: ¿puede reducir la necesidad de repetir la otoscopia para supervisar a los residentes? 儿科急诊中的数字听诊器：它能减少为监测住院病人而重复进行听诊器检查的需要吗？

IF 1.5 4区医学

Anales de pediatria Pub Date : 2025-04-01 DOI: 10.1016/j.anpedi.2025.503766

Ibai Hernández Morrás, Sara Rey Grimón, Ana Vázquez Morales, Maite González Mentxakatorre, Frederic Samson

引用次数: 0

Disrafismo espinal oculto pediátrico: importancia del diagnóstico precoz 儿童隐性脊柱疾患：早期诊断的重要性

IF 1.5 4区医学

Anales de pediatria Pub Date : 2025-04-01 DOI: 10.1016/j.anpedi.2025.503776

Inés Loreto Gallán Farina , Alba Fernández Gómez , Jesús Adrián Moles Herbera , Jesús Manuel Esteban García

引用次数: 0