Anales de pediatriaPub Date : 2026-08-01Epub Date: 2026-06-25DOI: 10.1016/j.anpedi.2026.504275
Alba Molina Ureba, Jessica Gómez Ávila
{"title":"Oxigenoterapia de alto flujo en ≤ 32 semanas de edad gestacional en un hospital de tercer nivel: estudio descriptivo retrospectivo y su asociación con la displasia broncopulmonar y retinopatía de la prematuridad","authors":"Alba Molina Ureba, Jessica Gómez Ávila","doi":"10.1016/j.anpedi.2026.504275","DOIUrl":"10.1016/j.anpedi.2026.504275","url":null,"abstract":"<div><h3>Introduction</h3><div>High-flow oxygen therapy (HFOT) is increasingly used for respiratory support in preterm newborns (PTNBs). However, there is still limited evidence regarding the impact of its early and prolonged use in this population, as well as its association with clinical outcomes such as bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP). The aim of our study was to describe our experience with the use of HFOT in PTNBs and to analyze its association with the prevalence of BDP and ROP.</div></div><div><h3>Material and methods</h3><div>Retrospective descriptive study conducted in a cohort of PTNBs born between May 2019 and May 2024 with gestational age ≤ 32 weeks who received HFOT during their stay in the neonatal intensive care unit of a tertiary care hospital. We analyzed data on variables related to HFOT exposure (duration, maximum flow, and FiO<sub>2</sub>) and the presence of BPD and ROP.</div></div><div><h3>Results</h3><div>In the analyzed cohort, we found a potential association between HFOT exposure parameters (days of use, maximum flow, and FiO<sub>2</sub>) and the presence of BPD. Likewise, we found evidence of a potential negative impact, as the duration of HFOT and the FiO<sub>2</sub> were associated with the presence of ROP. The frequency of both complications increased with lower gestational age and lower birth weight.</div></div><div><h3>Conclusions</h3><div>In this cohort, we observed a possible negative impact of the use of HFNC on the development of BPD and ROP, which was more evident in infants with lower gestational ages and birth weights. These findings should be interpreted with caution due to the descriptive design of the study and the lack of a comparison group, and analytical studies with appropriate control groups are required to further investigate these associations.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"105 2","pages":"Article 504275"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148660376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-08-01Epub Date: 2026-06-22DOI: 10.1016/j.anpedi.2026.504276
Yéssica Rodríguez Santana, Elena Sánchez Almeida, Paula Fernández Martínez, Begoña Domínguez Aurrecoechea, Ana María Lorente García-Mauriño, Red de Investigación de la Asociación Española de Pediatría de Atención Primaria (PAPenRED)
{"title":"Impacto de la lactancia materna en la morbilidad durante los 2 primeros años de vida","authors":"Yéssica Rodríguez Santana, Elena Sánchez Almeida, Paula Fernández Martínez, Begoña Domínguez Aurrecoechea, Ana María Lorente García-Mauriño, Red de Investigación de la Asociación Española de Pediatría de Atención Primaria (PAPenRED)","doi":"10.1016/j.anpedi.2026.504276","DOIUrl":"10.1016/j.anpedi.2026.504276","url":null,"abstract":"<div><h3>Introduction</h3><div>Breastfeeding (BF) is associated with multiple benefits for child health, including a reduction in infectious morbidity. The aim of this study was to analyse the association between type of feeding and morbidity during the first 2 years of life.</div></div><div><h3>Methods</h3><div>Secondary analysis of a large breastfeeding study based on a prospective multicentre cohort conducted by a Spanish Primary Care paediatric research network. A total of 320 paediatricians participated, each recruiting one newborn per month over a one-year period, with follow-up until 24 months of age. Data on demographic characteristics, type of feeding, and morbidity were collected at 7 visits (<15 days; 1, 2, 6, 12, 18, and 24 months). Common infant conditions and 19 prevalent acute and chronic diseases were analysed. Associations were estimated using models adjusted for confounding variables (presence of siblings and attendance at childcare centres).</div></div><div><h3>Results</h3><div>A total of 2,046 children were included. BF was associated with a lower frequency of common infant conditions, such as constipation, particularly at early visits (p<!--> <!--><<!--> <!-->0.001). In addition, lower infectious morbidity was observed among children who received BF, especially at 12 and 18 months (p<!--> <!--><<!--> <!-->0.001). BF was associated with a reduced risk of the most frequent acute infections, including acute otitis media, conjunctivitis, bronchiolitis, gastroenteritis, and wheezing episodes, with statistically significant adjusted associations (p<!--> <!--><<!--> <!-->0.005). Exclusive breastfeeding during the first 6 months was associated with lower overall morbidity in the medium term across the 19 conditions analysed at 12, 18, and 24 months, with a sustained protective effect particularly for the most prevalent diseases.</div></div><div><h3>Conclusions</h3><div>BF, especially when exclusive during the first 6 months of life, is associated with lower rates of common childhood morbidity during the first 2 years, with a protective effect that persists in the medium term.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"105 2","pages":"Article 504276"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148660320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-08-01Epub Date: 2026-06-26DOI: 10.1016/j.anpedi.2026.504292
Gülsüm Yitik Tonkaz, Gökhan Tonkaz, Hilmi Furkan Arslan, Hasan Deliağa, Ali Çakır
{"title":"Síntomas psicopatológicos en la población pediátrica con vejiga hiperactiva e hipoactiva","authors":"Gülsüm Yitik Tonkaz, Gökhan Tonkaz, Hilmi Furkan Arslan, Hasan Deliağa, Ali Çakır","doi":"10.1016/j.anpedi.2026.504292","DOIUrl":"10.1016/j.anpedi.2026.504292","url":null,"abstract":"<div><h3>Objectives</h3><div>The aim of the study was to assess psychiatric manifestations, including externalizing and internalizing symptoms, as well as anxiety and depression symptoms, in children diagnosed with overactive bladder (OAB) and underactive bladder (UAB).</div></div><div><h3>Methods</h3><div>The study included 53 children with a diagnosis of OAB, 23 children with a diagnosis of UAB, and 30 controls. Participating children completed the Revised Child Anxiety and Depression Scale–Child Version (RCADS-C), while their parents completed the Strengths and Difficulties Questionnaire (SDQ).</div></div><div><h3>Results</h3><div>There were no statistically significant differences among the three groups in terms of age, sex, socioeconomic status, or years of education (<em>P</em>>.05). The SDQ subscale comparisons revealed that children with OAB scored significantly higher in conduct problems, hyperactivity, and externalizing problems compared to both children with UAB and controls (<em>P</em>=.024, <em>P</em>=.013, and <em>P</em>=.034, respectively). No significant differences were found among groups in emotional symptoms, peer relationship problems, prosocial behavior, or internalizing problems (<em>P</em>>.05). Similarly, RCADS anxiety and depression scores did not differ significantly between groups (<em>P</em>>.05).</div></div><div><h3>Discussion</h3><div>Our findings suggest that externalizing psychiatric symptoms are more prevalent in children diagnosed with OAB than children with UAB or healthy controls. These behavioral issues may be associated with delayed cortical maturation. Longitudinal studies using neuroimaging techniques are needed to further explore this association. Routine screening for psychiatric symptoms in children with bladder dysfunction may improve treatment outcomes and support a more comprehensive care approach.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"105 2","pages":"Article 504292"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148660321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-08-01Epub Date: 2026-04-08DOI: 10.1016/j.anpedi.2026.504198
Ana Paola Jiménez Jiménez, Noemí Muñoz Quesada, Pilar Ranchal Pérez, Zineb Al Kalii El Moussaoui
{"title":"Reconocimiento precoz de la infección por virus del herpes simple en un recién nacido: importancia de las lesiones vesiculosas","authors":"Ana Paola Jiménez Jiménez, Noemí Muñoz Quesada, Pilar Ranchal Pérez, Zineb Al Kalii El Moussaoui","doi":"10.1016/j.anpedi.2026.504198","DOIUrl":"10.1016/j.anpedi.2026.504198","url":null,"abstract":"","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"105 2","pages":"Article 504198"},"PeriodicalIF":2.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148660373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-07-01Epub Date: 2026-04-15DOI: 10.1016/j.anpedi.2026.504230
Carolina Bonzi, Teresa Balboa-Castillo
{"title":"Valores de referencia de circunferencia de cintura e índice cintura-talla en niños y adolescentes paraguayos","authors":"Carolina Bonzi, Teresa Balboa-Castillo","doi":"10.1016/j.anpedi.2026.504230","DOIUrl":"10.1016/j.anpedi.2026.504230","url":null,"abstract":"<div><h3>Objective</h3><div>To establish reference values for waist circumference (WC) and waist-to-height ratio (WHR) for Paraguayan children and adolescents aged 7 to 18 years to improve early detection of abdominal obesity.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional study using a nationally representative sample of Paraguayan schoolchildren. The analysis included a total of 12 611 students from public, private, and subsidized educational institutions. We determined reference values using smoothed percentiles for WC and WHR using the lambda-mu-sigma (LMS) method, stratified by age and sex.</div></div><div><h3>Results</h3><div>Of the total sample, 52% of participants were female, 81% resided in urban areas, and 68% were enrolled in the public education system. Regarding nutritional status, 36% had malnutrition due to excess BMI for age, and 25% had abdominal obesity. We generated reference values for WC and WHR by age and sex in the form of tables and reference curves. The WC showed a progressive increase with age in both sexes, with higher values in male participants. At age18 years, the 90th percentile for WC reached values cl</div><div>ose to the WHO metabolic risk thresholds for adults in both sexes.</div></div><div><h3>Conclusions</h3><div>This study provides, for the first time, national reference values for CC and WHR for the Paraguayan pediatric population. The generated curves are valuable tools for screening abdominal obesity and can complement nutritional monitoring for the early detection of cardiometabolic risk at an early age.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"105 1","pages":"Article 504230"},"PeriodicalIF":2.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148558616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-07-01Epub Date: 2026-02-08DOI: 10.1016/j.anpedi.2026.504138
Carla Corberó Rivali, Asier Apodaca Saracho
{"title":"El signo de la granada en ecografía: una clave visual para la parotiditis aguda","authors":"Carla Corberó Rivali, Asier Apodaca Saracho","doi":"10.1016/j.anpedi.2026.504138","DOIUrl":"10.1016/j.anpedi.2026.504138","url":null,"abstract":"","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"105 1","pages":"Article 504138"},"PeriodicalIF":2.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148558627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-07-01Epub Date: 2026-05-07DOI: 10.1016/j.anpedi.2026.504234
Francisco José Climent, Heidy Johana Campo Palacio, María Falcón, Mar Gutiérrez Alvariño, Ricardo López-Almaraz, Rubén Berrueco
{"title":"Enfermedad tromboembólica en pediatría: abordaje de situaciones clínicas especiales","authors":"Francisco José Climent, Heidy Johana Campo Palacio, María Falcón, Mar Gutiérrez Alvariño, Ricardo López-Almaraz, Rubén Berrueco","doi":"10.1016/j.anpedi.2026.504234","DOIUrl":"10.1016/j.anpedi.2026.504234","url":null,"abstract":"<div><h3>Introduction</h3><div>The incidence of pediatric venous thromboembolism (VTE) has increased due to increased health care complexity, improved diagnostic techniques, and greater clinical awareness. Most episodes are associated with iatrogenic risk factors, particularly the use of central venous catheters, and occur in vulnerable populations such as neonates or children with cancer, congenital heart disease, and/or short bowel syndrome.</div></div><div><h3>Objective</h3><div>To review special clinical scenarios of pediatric VTE and propose a practical approach to support decision-making in complex clinical settings.</div></div><div><h3>Methods</h3><div>Narrative review focused on clinical practice, addressing pathophysiological features, diagnosis, treatment, and follow-up, integrating recent guideline recommendations, observational case series, and clinical experience reports.</div></div><div><h3>Results</h3><div>In neonatology, developmental hemostasis, bleeding risk, and pharmacokinetics influence the indication, selection, and monitoring of anticoagulation therapy. The review discusses umbilical venous catheter-associated thrombosis, neonatal purpura fulminans, and renal and portal vein thrombosis, highlighting the criteria for anticoagulation and/or thrombolysis and the need for long-term follow-up to detect sequelae. In children with cancer, congenital heart disease, or short bowel syndrome, VTE is multifactorial and frequently catheter-related, requiring therapeutic adjustments (eg, thrombocytopenia, invasive procedures, preservation of vascular access). We summarize the current strategies for anticoagulation—including the emerging role of direct oral anticoagulants, with caution in selected subgroups—and thrombolysis.</div></div><div><h3>Conclusions</h3><div>In special pediatric populations, VTE requires individualized and multidisciplinary management. Disease severity, residual risk, and the need to balance bleeding and thrombosis should guide decisions regarding treatment intensity/duration as well as prophylaxis, with emphasis on organ preservation, maintenance of venous capital, and prevention of long-term complications.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"105 1","pages":"Article 504234"},"PeriodicalIF":2.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148558623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anales de pediatriaPub Date : 2026-07-01Epub Date: 2026-04-22DOI: 10.1016/j.anpedi.2026.504232
Itziar Iturralde Orive, Marina Sánchez de Medina
{"title":"Vacunación antigripal en grupos pediátricos de riesgo: entre la recomendación y la realidad asistencial","authors":"Itziar Iturralde Orive, Marina Sánchez de Medina","doi":"10.1016/j.anpedi.2026.504232","DOIUrl":"10.1016/j.anpedi.2026.504232","url":null,"abstract":"","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"105 1","pages":"Article 504232"},"PeriodicalIF":2.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148558619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}