{"title":"[Etiology and epidemiology of cancer].","authors":"Y Valladares","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 4","pages":"741-55"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15030442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Effect of tamoxifen on blood calcium and bone structure of normal and ovariectomized rats].","authors":"G Manso, J Sala, F Andrés-Trelles, A Hidalgo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of tamoxifen on calcaemia and framework was studied, both in normal and ovariectomized rats. Tamoxifen caused hypercalcaemia. Only in one of seven animals hypercalcaemia due tamoxifen was accompanied by radiological changes although no structural modification was histologically evident. In ovariectomized rats, tamoxifen dit not produce either hypercalcaemia or radiological changes. These data suggest that the antioestrogenic activity of tamoxifen is involved in the hypercalcaemia it produces.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 3","pages":"411-8"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14986364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Pérea García, F Rico Mena, J L Prieto Alonso, J M Guerra Flecha
{"title":"[Epidemiology and diagnosis of cervical cancer].","authors":"C Pérea García, F Rico Mena, J L Prieto Alonso, J M Guerra Flecha","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors study 567 medical histories of women with cancer of the uterine cervix. They describe the data in relation to epidemiology and cytology, colposcopy, and the procedure for an early diagnosis.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 4","pages":"641-8"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14997153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Action of radiation on the lung. Classic concepts and current interpretations].","authors":"A Villar, M Hernández, S Villa, R Galiana","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of irradiation on the pulmonary system are analyzed according to the classical radiobiological theories and the new ones. Special emphasis is put on the lineal-quadratic model which predicts the possibility of a greater tumor control without increasing the damage to the normal lung tissue, based on the differences between the survival curves for acute and late effects of irradiation. The clinical applications of the new radiobiological concepts can be carried out in the treatment of lung cancer and other neoplasms, especially those using total body irradiation.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 3","pages":"557-73"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15031935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Examples of the usefulness of tumor biological markers in the diagnosis and follow-up of various tumors].","authors":"Y Valladares","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>As an example of the usefulness of biological tumor markers for the diagnosis and following up of some tumors, the author reviews briefly their application in lung cancer, breast cervix uteri, prostate cancer and acute lymphoblastic leukemia.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 2","pages":"349-61"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14984330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Gastric carcinoma in Cantabria: I. Incidence and distribution].","authors":"C Blanco García, J F Val Bernal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We have proceeded to study the rate of incidence and distribution in Cantabria of six hundred and thirty two patients suffering from gastric carcinoma in a period of time ranging from 1970 to 1981. The rate of incidence being observed among this population amounts to 14.54, cases per one hundred thousand inhabitants and year between 1976-1981. This rate increases with age in women more than in men. We have also been able to see how those cases where the carcinoma has appeared at an early age, under thirty, concern females exclusively. Males have been affected by this pathology more than females in a proportion of 1.38:1. We have verified there exists a special geographical distribution of this kind of tumour in our region, being Reinosa the judicial district presenting the highest rate of incidence.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 3","pages":"487-95"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14987356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P Miranda Serrano, A Pérez Torrubia, J Bajo Arenas, J Grande García
{"title":"[Our results in the treatment of infiltrating carcinoma of the cervix].","authors":"P Miranda Serrano, A Pérez Torrubia, J Bajo Arenas, J Grande García","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors analyze the past history, evolution and results of therapy in 71 cases of invasive cervical carcinoma seen between 1980 and 1984. They are comparable to those published in the world literature.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 4","pages":"719-31"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15030441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A García Vilanova, R A Company Serrano, E Fuster Diana, F Checa Ayet, R Trullenque Peris, A García-Vilanova Comas
{"title":"[The 1978 TNM system for cancer of the breast: proposal for a modification].","authors":"A García Vilanova, R A Company Serrano, E Fuster Diana, F Checa Ayet, R Trullenque Peris, A García-Vilanova Comas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors study the 5 and 10 years survival of 1.058 cases of breast carcinoma treated between 1963 and 1981, classified according to the pTNM system. They suggest the convenience of eliminating some of the combinations in order to obtain a good correlation with prognostic criteria. The authors propose a modification of the TNM system with closer clinical significance.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 1","pages":"95-108"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14959487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Study and characterization of lipid factors that inhibit cellular proliferation in MCG3 rat T lymphoma].","authors":"R Rueda, R Fiestas, R Bordés, E García-Olivares","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lipid factors that inhibit cellular proliferation have been detected in MCG3 cells, a T lymphoma of B10 mouse. The inhibiting effect is cytostatic, non cytotoxic, reversible and lacks species and tissue-specificity. These lipids have been isolated by Thin Layer Chromatography (chloroform:methanol:water, 60:38:8) showing an Rf100 between 36 and 42, similar to that shown by gangliosides and phosphatidylinositol.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 4","pages":"617-25"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14997211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F R Pérez-López, H K Lorenzo, M A Urcia, J Hergueta, L Lafarga, V Guillen
{"title":"Lack of effect of indomethacin on the growth of N-nitrosomethylurea-induced rat mammary tumors.","authors":"F R Pérez-López, H K Lorenzo, M A Urcia, J Hergueta, L Lafarga, V Guillen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Elevated prostaglandin levels have been previously reported in mammary tumors. This study was designed to determine if treatment with indomethacin, a prostaglandin synthesis inhibitor, influenced the growth of N-nitrosomethylurea-induced mammary tumors in Wistar rats. Indomethacin was given in drinking water to tumor-bearing rats, and rats consumed between 2.5 and 3.0 mg/kg body weight/day. Continuous p.o. administration of indomethacin during 4 weeks did not affect the rate of tumor growth as compared to the control group of untreated rats. It can be concluded that indomethacin lack of effect on N-nitrosomethylurea-induced mammary tumors, and this may be due to a specific prostaglandin profile as compared with previous results using other experimental models.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 1","pages":"15-21"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14959481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}