[Study and characterization of lipid factors that inhibit cellular proliferation in MCG3 rat T lymphoma].

Abstract

Lipid factors that inhibit cellular proliferation have been detected in MCG3 cells, a T lymphoma of B10 mouse. The inhibiting effect is cytostatic, non cytotoxic, reversible and lacks species and tissue-specificity. These lipids have been isolated by Thin Layer Chromatography (chloroform:methanol:water, 60:38:8) showing an Rf100 between 36 and 42, similar to that shown by gangliosides and phosphatidylinositol.