J Cueto Ladrón de Guevara, J Villalba Moreno, J L García Puche, V Pedraza
{"title":"[Prolactin and human cancer of the breast. I. Levels of correlation].","authors":"J Cueto Ladrón de Guevara, J Villalba Moreno, J L García Puche, V Pedraza","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The correlation between breast cancer and serum prolactin levels in women is not so clear as it is in experimental animals. The study described in this work shows that there are no significant differences in prolactin levels in normal women and breast cancer patients, but that there is a direct relation between prolactin level and tumor mass in every patient.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 3","pages":"439-58"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14986366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P Miranda Serrano, J Grande García, C Gómez Alvarez, J Granada Corrochano
{"title":"[Epidemiologic factors in cervical intraepithelial neoplasia III in our experience].","authors":"P Miranda Serrano, J Grande García, C Gómez Alvarez, J Granada Corrochano","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The study of 52 cases of cervical intraepithelial neoplasia seen from 1980 to 1984 shows that early sexual activity increases the relative risk 3.35 times if the intercourse takes place before 20 years of age, and 2.5 times if before 15 years. The use of IUD increases the risk 2.77 times. Parity, civil status and gynecologic infections do not increase the risk. Cervical intraepithelial neoplasia is more frequently diagnosed in women with a higher socio-economic status, due to a better health care.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 4","pages":"657-70"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14997155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Nuclear medicine in osteoarticular pathology].","authors":"O Caballero Carpena","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The author writes about some facts related to the use of 99m-Tc-phosphate in skeletal scanning, specially to recognize cancer metastases, and vascular and inflammatory osseous diseases, and indicates some conditions to carry out the study.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 3","pages":"551-5"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15031934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Indications for radiotherapy in cancer of the pancreas].","authors":"S Ripol Girona","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Radiotherapy of pancreas is usually difficult because of the vicinity of important organs (stomach, small bowel, liver and kidneys) that may result damaged. However, the use of new T.A.C. procedures and the better employment of precision high energy radiotherapy permit the application of a valuable procedure in about fifty per cent of the cases to relieve the pain usually associated to pancreatic carcinoma. The procedure followed at the Radiotherapy Service of the \"Hospital General. Ntra. Sra. de la Esperanza\", in Barcelona is detailed, making a review of the experience from 1973-1985. Radiotherapy was always associated to chemotherapy.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 2","pages":"315-22"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14960705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[In vitro studies of the effect of a pulsed electromagnetic field on normal and cancer cells].","authors":"C Rius, Y Alvarez-Rodríguez, Y Valladares","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of an electromagnetic field of 100 Hz during 5 msec on HeLa, MMT and LMMB cell lines in vitro was investigated by means of videophotomicrography. An inhibition of cell growth of cancer cells was observed after the simultaneous action of light and electromagnetic field. The combined effect was also proved using plating efficiency tests.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 1","pages":"55-84"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14959485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[In vitro combination of mercaptopurine and human serum albumin].","authors":"G Frutos, C Mora, C Rueda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Through the use of the fluorescence absorbance technique, the parameters that define the association between the antineoplastic drug mercaptopurine and human serum albumin were determined for a concentration range for the ligand between 6 X 10(-5) and 10(-7) moles/L, keeping the concentration of the macromolecule fixed at 0.5 X 10(-6) moles/l. Given the structure of the macromolecule under study and the experimental conditions used, we established an association model with two different kinds of binding sites.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 2","pages":"255-63"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14960700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Bascuas, T Gutiérrez, J E Trigo, L Machuca, J L Bascuas
{"title":"[Radiological study of carcinoma of the lung in stage III].","authors":"S Bascuas, T Gutiérrez, J E Trigo, L Machuca, J L Bascuas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A radiologic study of 50 patients with stadium III lung cancer is made. The main radiologic signs were an opacity indicating a mass (100%), hilar widening (70%), mediastinal widening (40%), atelectasis 40% and pneumonitis (34%). The most common histologic diagnosis found was that of squamous carcinoma (38%).</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 2","pages":"343-8"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14960707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Biological markers in cancer of the ovary].","authors":"Y Valladares","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The organism produces substances whose presence or amount indicate the existence of a neoplastic process, called biological tumor markers. They can be used in the clinical laboratory for diagnostic purposes, and also to orient about the evolution of the tumoral mass. There are about 90 tumor markers, 33 of them have studied in relation to cancer of the ovary, that are described in this work. Eight of them are the most important: CSAp, OCA, OCAA, IAP, Nagao's isoenzyme, hCG/hCG beta, hPL, and AFP.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 2","pages":"363-73"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14960708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L S Rumi, N A Chasseing, A Couto, R M de Lederkremer
{"title":"Inhibition of tumor growth and leukocyte alterations in splenectomized mice treated with a PCj3 polysaccharide.","authors":"L S Rumi, N A Chasseing, A Couto, R M de Lederkremer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of a polysaccharide (PCj3), isolated from the ascomycete \"Cyttaria johowii\" was studied on the growth of the ascitic Sarcoma 180 (S180) inoculated subcutaneously in BALB/c mice which had been previously splenectomized. The leukocyte alterations in peripheral blood were analyzed simultaneously, and the percentage of cells with C3b receptors in the population of peritoneal cavity was evaluated through the E (IgM)C rosette technique. A significant inhibition of tumor growth was observed in the splenectomized mice treated with PCj3 with respect to the untreated splenectomized and to the control group, which had not been splenectomized. It was also found that the first group acquired relative resistance to the later inocula of the ascitic S180 via i.p. On the day 8 after the tumor inoculation a marked lymphocytosis increased up to 224% in PCj3 treated mice and only to 59% in untreated splenectomized mice. The increase in the controls, that had not been splenectomized was 18%. With regard to the number of neutrophils a significant difference was found between both splenectomized groups on the 8 day, corresponding the highest values to the group treated with PCj3. No differences were observed on the 25 day even though the neutrophilia was maintained. The percentage of cells with C3b receptors in population of peritoneal cavity was significantly lower in mice treated with PCj3, although an increase in the number of E (IgM)C attached per cell and ingestion of system were observed.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 2","pages":"215-26"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14962786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Expósito, N Olea, J M Ruiz de Almodovar, V Pedraza
{"title":"[Determination of estrogen and progesterone receptors in cancer of the breast. Frequency of presentation and prognostic significance].","authors":"J Expósito, N Olea, J M Ruiz de Almodovar, V Pedraza","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The assay of estrogen and progesterone receptors (RE and RP) is used to know the hormone dependency of breast tumors and to predict the response to endocrine therapy. In this study 68 per 100 of the patients were RE(+) within a range of 5 to 180 fmol/mg, and 45 per 200 were RP(+) between 10 and 400 fmol/mg. The frequency and concentration increase with age. Significative variations were not observed in RE(+) for either frequency or concentration between primary and metastatic samples. There is a correlation between phenotypes RE(+) and RE(-) and histopathologic prognostic features.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 3","pages":"471-85"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14986368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}