[Determination of estrogen and progesterone receptors in cancer of the breast. Frequency of presentation and prognostic significance].

Revista espanola de oncologia Pub Date : 1985-01-01
J Expósito, N Olea, J M Ruiz de Almodovar, V Pedraza
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Abstract

The assay of estrogen and progesterone receptors (RE and RP) is used to know the hormone dependency of breast tumors and to predict the response to endocrine therapy. In this study 68 per 100 of the patients were RE(+) within a range of 5 to 180 fmol/mg, and 45 per 200 were RP(+) between 10 and 400 fmol/mg. The frequency and concentration increase with age. Significative variations were not observed in RE(+) for either frequency or concentration between primary and metastatic samples. There is a correlation between phenotypes RE(+) and RE(-) and histopathologic prognostic features.

乳腺癌中雌激素和孕激素受体的测定。出现频率及预后意义]。
雌激素和孕激素受体(RE和RP)的测定用于了解乳腺肿瘤的激素依赖性和预测对内分泌治疗的反应。在这项研究中,每100名患者中有68名在5至180 fmol/mg范围内为RE(+),每200名患者中有45名在10至400 fmol/mg范围内为RP(+)。频率和浓度随年龄增加而增加。在原发和转移样本中,RE(+)的频率或浓度均未观察到显著差异。表型RE(+)和RE(-)与组织病理学预后特征之间存在相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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