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Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao最新文献

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Diagnosis and treatment of idiopathic necrosis of the femoral head. 特发性股骨头坏死的诊断与治疗。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1990-01-01
Y Z Li, T Yue
{"title":"Diagnosis and treatment of idiopathic necrosis of the femoral head.","authors":"Y Z Li,&nbsp;T Yue","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fifteen cases, 27 hips, of idiopathic necrosis of the femoral head (INFH) were included in our series. The roles of radiography, isotopic bone scanning, intraosseous pressure measurement and intraosseous venography in the diagnosis of INFH were evaluated. Radiological examination could not reveal early cases, while isotopic bone scanning was more sensitive. There was an increase of intraosseous pressure in most of the diseased hips, and intraosseous venography showed abnormalities in all examined hips. The latter two tests could therefore detect early INFH. Core decompression was performed in 23 hips, 21 of which were followed for 7 to 27 months. Functional evaluation was good or excellent in 18 hips. Radiological re-examination remained unchanged in 19 hips. Postoperative intraosseous pressure measurement and intraosseous venography revealed a decrease of intraosseous pressure and improvement of venous drainage. Core decompression is therefore an ideal method of treatment for early INFH.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"5 2","pages":"88-92"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13395807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunological classification of 31 multiple myeloma patients. 31例多发性骨髓瘤患者免疫学分型分析。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1990-01-01
W X Qiu, N H Huang, G H Wu
{"title":"Immunological classification of 31 multiple myeloma patients.","authors":"W X Qiu,&nbsp;N H Huang,&nbsp;G H Wu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Thirty-one multiple myeloma patients were classified chiefly by heavy and light chain detection of myeloma protein (M protein). The results were as follows: 19 out of the 31 cases belonged to the IgG class, including the following subclasses--IgG1-lambda, 7; IgG1-k, 5; IgG3-lambda, 1; IgG3-k, 2; double M myeloma, 2 (IgG3-lambda + IgG2-k, IgG1-lambda + IgG4-lambda); IgG-lambda, 1; and IgG1-k 1. Seven cases were light chain diseases, of which 4 belonged to lambda type, 2 were k, and one was a double light chain disease. Five cases belonged to the IgA class (IgA-lambda, 3; IgA-k, 2). We found no correlation between electrophoretic mobility and the antigenicity of M protein even within subclasses, and the highly concentrated BJP in urine had a tendency to form light chain polymers, possibly along different polymerization pathways.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"5 2","pages":"79-83"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13277298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The first report of experimental atherosclerosis in Chinese mini-pigs. 中国小型猪实验性动脉粥样硬化的首次报道。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1990-01-01
R Sun, D Wang
{"title":"The first report of experimental atherosclerosis in Chinese mini-pigs.","authors":"R Sun,&nbsp;D Wang","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"5 4","pages":"216-8"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13443648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical treatment for recurrent ovarian malignancies. 复发性卵巢恶性肿瘤的手术治疗。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1990-01-01
A Sun, L Lian, M Tang
{"title":"Surgical treatment for recurrent ovarian malignancies.","authors":"A Sun,&nbsp;L Lian,&nbsp;M Tang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Eighty-nine cases of recurrent ovarian malignancies which had undergone surgical treatment were studied. Debulking surgery is of great value in the treatment of primary ovarian carcinoma, but for recurrent carcinomas success depends upon the pathological type. The 5-year survival rate was 75% for patients with immature teratomas, but only 6.1% for those with epithelial ovarian carcinomas and 3.6% with endodermal sinus tumors. Two cases of recurrent dysgerminoma were both alive and well more than 10 years after treatment. So repeated debulking is worthwhile for recurrent immature teratoma and dysgerminoma, while in cases of epithelial type or endodermal sinus tumors successful debulking surgery should be followed by some new kinds of adjuvant therapy, otherwise only failure will result.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"5 4","pages":"219-22"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13443649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of purified compound (8501) on hyperlipidemia and the balance between thromboxane A2 and prostacyclin in rabbits. 纯化化合物(8501)对家兔高脂血症及血栓素A2与前列环素平衡的影响。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1990-01-01
Z Wang, Y Hu, Y An, G Zhu, R Huang, R Xia, B Zhang
{"title":"Effects of purified compound (8501) on hyperlipidemia and the balance between thromboxane A2 and prostacyclin in rabbits.","authors":"Z Wang,&nbsp;Y Hu,&nbsp;Y An,&nbsp;G Zhu,&nbsp;R Huang,&nbsp;R Xia,&nbsp;B Zhang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>New Zealand strain white male rabbits were divided into four groups to study the effects of 8501, extracted from a Chinese herb, on hyperlipidemia and the TXA2/PGI2 ratio in atherosclerotic rabbits. The results indicate that serum cholesterol and the levels of cholesterol and cholesteryl ester in aortic tissue were significantly increased in cholesterol-fed rabbits. The percentage of alpha-lipoprotein was significantly decreased and the aortic atherosclerotic plaque area was significantly increased. The data also demonstrate that the level of plasma TXB2 was markedly increased, while that of 6-keto-PGF1 alpha was significantly decreased. The TXB2/6-keto-PGF1 alpha ratio (T/6) was significantly increased. The decrease of 6-keto-PGF1 alpha occurred prior to the increase of TXB2. Compound 8501 not only lowered serum total cholesterol and aortic total cholesterol and cholesteryl ester but also antagonized the decrease of alpha-lipoprotein and atherosclerotic plaque formation. In addition, 8501 prevented the decrease of plasma 6-keto-PGF1 alpha and the increase of TXB2, and so the T/6 ratio was significantly decreased.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"5 4","pages":"228-32"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13443652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The characterization of EIAV reverse transcriptase and its inhibition by 5'-triphosphates of 2'-deoxyuridine analogs, PFA and PAA. 2'-脱氧尿苷类似物的5'-三磷酸、PFA和PAA对EIAV逆转录酶的抑制作用。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1990-01-01
P Tao, X Zhang, K Quan
{"title":"The characterization of EIAV reverse transcriptase and its inhibition by 5'-triphosphates of 2'-deoxyuridine analogs, PFA and PAA.","authors":"P Tao,&nbsp;X Zhang,&nbsp;K Quan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A characterization of equine infectious anemia virus reverse transcriptase (EIAV RT) and its inhibition by 5'-triphosphate analogs was undertaken to explore the possibility of using EIAV RT as an in vitro model for studying human immunodeficiency virus (HIV). EIAV RT activity was found to be dependent on the bivalent cations Mg++ and Mn++. The optimal pH for enzyme reaction was pH 8.2. EIAV RT preferred a 70 mmol/L concentration of monovalent salts. Phosphonoformic acid (PFA) was an active inhibitor of EIAV RT, but phosphonoacetic acid (PAA) and N-ethylmaleimide (NEM) were not. The inhibition of EIAV RT activity by 5'-triphosphates of nucleoside derivatives was in the following decreasing order: FLTTP greater than AZTTP greater than nPrearaUTP greater than nPredUTP = CEdUTP greater than EtdUTP greater than nPrdUTP greater than HMdUTP. nPrearaUTP was a linear competitive and PFA a linear noncompetitive inhibitor of EIAV RT with respect to dTTP. Apparent Kis and Kii were 1.5 and 2.2 mumol/L respectively. The susceptibility pattern of EIAV RT to inhibitors was similar to that of HIV RT.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"5 3","pages":"130-4"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12875791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of HPV-16 DNA in cervical carcinoma by paraffin section in situ hybridization. 石蜡切片原位杂交法检测宫颈癌组织中HPV-16 DNA。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1990-01-01
W Zhang, Y Sun, M Shang, S Jin, X Liang, K Liang, A Wu, G Nan, X Wang, W Zhang
{"title":"Detection of HPV-16 DNA in cervical carcinoma by paraffin section in situ hybridization.","authors":"W Zhang,&nbsp;Y Sun,&nbsp;M Shang,&nbsp;S Jin,&nbsp;X Liang,&nbsp;K Liang,&nbsp;A Wu,&nbsp;G Nan,&nbsp;X Wang,&nbsp;W Zhang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Thirty-eight cervical carcinomas and 1 cervical condyloma were examined for the presence of human papillomavirus (HPV) type 16 DNA using 3H-dCTP-labelled HPV-16 DNA probe in paraffin section in situ hybridization and 32P-dCTP-labelled probe in dot blot hybridization (Tm-17). The results showed an HPV-16 DNA positive rate in our series of about 74.4% (29/39) as determined by paraffin section in situ hybridization and about 71.8% (28/29) by dot blot hybridization. There was no significant difference between the two methods. We thus confirmed that paraffin section in situ hybridization is an informative, reliable, and sensitive method for the diagnosis of cervical HPV infection.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"5 3","pages":"174-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13125436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A proposed clinical classification of pelvic endometriosis. 盆腔子宫内膜异位症的临床分类建议。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1990-01-01
A Sun, M Han
{"title":"A proposed clinical classification of pelvic endometriosis.","authors":"A Sun,&nbsp;M Han","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two hundred and forty-four cases of pelvic endometriosis were diagnosed by laparoscopy between Jan. 1979 and Dec. 1986. Consulting the principles designated by the American Fertility Society (AFS) and Revised American Fertility Society (RAFS) classification, diseases were staged as mild, moderate and severe. The results of clinical classification were compared with those of laparoscopic classification. The conformance rate between clinical and RAFS classification was 74.2%. The pregnancy rates after operation were 69.2%, 42.9% and 38.5% among 94 patients clinically classified as mild, moderate and severe, respectively, as compared with 65.2%, 41.4% and 35.7% in terms of RAFS classification. The authors point out that laparoscopy is an excellent procedure for diagnosing and staging endometriosis. In hospitals where laparoscopic equipment is not available, clinical classification can be used as a substitute for staging those highly suspected of having endometriosis.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"5 3","pages":"163-7"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13306138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of patients with malignant pleural effusions due to advanced lung cancer by transfer of autologous LAK cells combined with rIL-2 or rIL-2 alone. 自体LAK细胞联合rIL-2或单独il -2移植治疗晚期肺癌恶性胸腔积液
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1990-01-01
D Li, Y Wang, X Yao, J Shao, Y Chen, D Ba
{"title":"Treatment of patients with malignant pleural effusions due to advanced lung cancer by transfer of autologous LAK cells combined with rIL-2 or rIL-2 alone.","authors":"D Li,&nbsp;Y Wang,&nbsp;X Yao,&nbsp;J Shao,&nbsp;Y Chen,&nbsp;D Ba","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"5 1","pages":"51-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13522076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro influence of enkephalins on the proliferative response of mouse and rat splenic lymphocytes to phytohemagglutinin. 脑啡肽对小鼠和大鼠脾淋巴细胞对植物血凝素增殖反应的体外影响。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1990-01-01
J Lin, G Lu, G Jiang
{"title":"In vitro influence of enkephalins on the proliferative response of mouse and rat splenic lymphocytes to phytohemagglutinin.","authors":"J Lin,&nbsp;G Lu,&nbsp;G Jiang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The opioid peptides leucine enkephalin (LENK) and methionine enkephalin (MENK) were investigated for their effect on the proliferative response of activated BALB/C mouse and Sprague-Dawley rat splenic lymphocytes in vitro. The results showed that LENK and MENK (1 x 10(-3) mg/ml to 1 x 10(-13) mg/ml) significantly suppressed the proliferative response of mouse lymphocytes to phytohemagglutinin (PHA) and enhanced the proliferation of rat lymphocytes at peptide concentrations similar to those effective in mice. It is proposed that endogenous ENKs play a neuroendocrine role between the central nervous system and the immune system.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"5 3","pages":"145-8"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13253866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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