{"title":"[Analysis of hospitalized tuberculosis patients at the Institute for Pulmonary Diseases and Tuberculosis in Belgrade, Serbia during 1988].","authors":"G Radosavljević, J Raković, N Bogdanović, V Kacar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The report presents the analysis of TB patients treated at the Institute for lung diseases and tuberculosis of SR of Serbia during 1988--a total of 567 or 10.18% of discharged patients. There were 77% TB patients from Belgrade and 23% from the province. Tuberculosis retains the characteristics of a social disease with a morbidity peak in the fourth decade of age. There were 93% of cases discovered due to disease symptoms. In 82% of patients it was a case of newly discovered specific process, 7.5% had a recurrent disease and 10.5% of patients had a chronic form of the disease. The patients had almost all forms of the specific process: primary tuberculosis 0.35%, postprimary phthisis 84.4%, specific pleuritis 10.6%, tuberculom 1.9%, miliary tuberculosis 1.8%, lymphoglandular tuberculosis 0.9%, while 1.4% had extrathoracic specific lesions associated with pulmonary lesions. Cavernous tuberculosis was observed in 89% of TB patients and extensive phthisis in 14% of cases. Atypical forms of parenchymal specific process were observed in 12% patients. Bacteriological or histological confirmation of tuberculosis existed for 82%. In 13% of patients treatment lasted longer than 3 months. Six or 1% of patients died due to pulmonary tuberculosis.</p>","PeriodicalId":77589,"journal":{"name":"Plucne bolesti : casopis Udruzenja pneumoftiziologa Jugoslavije = the journal of Yugoslav Association of Phthisiology and Pneumology","volume":"42 1-2","pages":"117-22"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13369202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z Dimcić, S Tanurdzić, J Balaban, V Durić, L Tomasević
{"title":"[Simultaneous recording of nonspecific bronchial response using continuous measurement of total respiratory resistance and oxygen saturation of arterial blood].","authors":"Z Dimcić, S Tanurdzić, J Balaban, V Durić, L Tomasević","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 78 patients with bronchial asthma symptoms undergoing nonspecific bronchial response test with bronchoprovocation inhalation of progressively increased methacholine concentrations, total respiratory resistance (Rrs) and oxygen saturation (SaO2) of arterial blood were continually measured. An average Rrs increase was 153% when compared to the initial values and it correlated with SaO2 decrease (5.5% of the initial values). In 45 patients along with continual Rrs and SaO2 measurements, bronchoprovocation test and spirogram flow-volume curve were periodically done. Ten of these patients had no significant Rrs or FEV1 changes, but there was a considerable drop in FEF50, FEF25 and SaO2. These results, associated with dyspnea and physical pulmonary findings in the course of BPT, as well as history of patients with similar difficulties in every-day life and in work environment, point to the need of expanding diagnostic criteria for positive BPT and for patients who did not have Rrs increased double the initial values nor sufficient FEV1 20% drop. Spirometry and oximetry as complementary methods, increase Astograph sensitivity to methacholine test. Oximetry has an advantage of enabling continual SaO2 monitoring and increased patient's safety during the BPT.</p>","PeriodicalId":77589,"journal":{"name":"Plucne bolesti : casopis Udruzenja pneumoftiziologa Jugoslavije = the journal of Yugoslav Association of Phthisiology and Pneumology","volume":"42 1-2","pages":"57-9"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13370757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Analysis of immunocompetent cells in bronchoalveolar lavage in patients with sarcoidosis].","authors":"I Tomić, M Colić, D Lilić, A Dujić, V Dangubić","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bronchoalveolar lavage through fiberoptic bronchoscope was performed in the right middle lobe or lingula of 8 patients with clinically and radiologically active sarcoidosis and 5 healthy persons. Pellet cells were analysed. Lymphocyte subsets were detected with monoclonal antibodies by fluorescent microscopy or flow cytometry (EPICS-C, Coulter). In patients with sarcoidosis lymphocyte proportion is elevated (29.88 +/- 4.32) as compared to healthy persons (5.2 +/- 3.4). We detected an increase of CD 3 lymphocytes (86.38 +/- 6.71) and CD 4 helper-inducer T lymphocytes compared to the total number of lymphocytes and, likewise, of the CD 4/CD 8 ratio--5.62 +/- 0.94. CD 8 suppressor-cytotoxic T lymphocytes are decreased (13.0 +/- 1.3 as compared to the healthy persons 22.0 +/- 3.84), which is a relative decrease because due to an increase of the total lymphocyte number, an increase of CD 8 T lymphocytes (3.85 +/- 0.41 as compared to the healthy persons 1.09 +/- 0.59) still exists, compared to the total number of pellet cells.</p>","PeriodicalId":77589,"journal":{"name":"Plucne bolesti : casopis Udruzenja pneumoftiziologa Jugoslavije = the journal of Yugoslav Association of Phthisiology and Pneumology","volume":"42 1-2","pages":"92-4"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13371495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Nonspecific bronchial response in asymptomatic female smokers and nonsmokers].","authors":"S Grobovsek-Opara","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 20 female smokers aged 21-58 yrs and 20 nonsmokers aged 22-48 yrs the effect of smoking on bronchial responsiveness was studied. In the study only those subjects were included who had no asthma and who had been without symptoms of any of the pulmonary disease and they had normal mean values of pulmonary function testing. In no subject the increase of bronchial responsiveness after maximal dose of 4 mg of metacholine was found. Since the statements in the literature are contradictory, further studies are necessary in order to clear up the effect of smoking on bronchial responsiveness.</p>","PeriodicalId":77589,"journal":{"name":"Plucne bolesti : casopis Udruzenja pneumoftiziologa Jugoslavije = the journal of Yugoslav Association of Phthisiology and Pneumology","volume":"42 1-2","pages":"22-3"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13369165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Evidence of the harmful effects of eosinophils in bronchial asthma].","authors":"B Mehić, A Konjicija, H Zutić, Z Lukić","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fifteen asthmatic patients were prospectively selected. If they had more than 450 eosinophils in peripheral blood on admission to hospital treatment and if before BAL had been performed they were not treated by corticosteroids. No associated disease was found which could cause the increased number of eosinophils in peripheral blood except bronchial asthma. BAL was performed when the subjects tested had no dyspnea, usually 1-3 days after the hospital admission. In contrast to blood eosinophilia, increase of eosinophils number in BAL was found to correlate to impairment of clinically measured parameters such as: ventilation level of blood gases and duration of hospitalisation. On the contrary there was no correlation between the level of blood eosinophilia and gas disturbance and duration of hospitalisation. Eosinophilic proteins (MBP, ECP, EPX, EPO) are not the only that harmfully effect the lung cells in the asthmatic attack but the fact that their level in lavage fluid correlates to eosinophilia degree in BAL is evident so the correlation between the number of eosinophils in BAL and impairment of clinically measured parameters is clear.</p>","PeriodicalId":77589,"journal":{"name":"Plucne bolesti : casopis Udruzenja pneumoftiziologa Jugoslavije = the journal of Yugoslav Association of Phthisiology and Pneumology","volume":"42 1-2","pages":"104-6"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13369199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The intensity of bronchial hyperreactivity and the evolution of pulmonary function].","authors":"P Trandafilovski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The relationship between the degree of the bronchial hyperreactivity (BH) and evolution or prognosis of the bronchial asthma is determined in this prospective study. BH has been examined in 108 asthmatic children and after a long period of time (average 5.5 years), the pulmonary function (VC, FEV1, FEF25-75, Raw, IGV, RV/TLC, flow-volume curve was evaluated. Impaired pulmonary function was found not to correlate with the degree of the BH. It is concluded that the degree of the BH might predict the evolution and the prognosis of the bronchial asthma.</p>","PeriodicalId":77589,"journal":{"name":"Plucne bolesti : casopis Udruzenja pneumoftiziologa Jugoslavije = the journal of Yugoslav Association of Phthisiology and Pneumology","volume":"42 1-2","pages":"36-7"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13369169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Inflammation of the bronchial mucosa as the basis for airway hyperreactivity].","authors":"R Dukanović","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The mechanisms that are involved in asthma pathogenesis have been the subject of intensive research in the last few years. Numerous studies have shown involvement of inflammatory cells and their mediators in the damage of the bronchi. Inflammation leads to morphological changes in the bronchial wall: damage of the epithelium, increased deposition of collagen beneath the epithelial basement membrane, oedema and infiltration of the mucosa with inflammatory cells, hyperplasia of the mucous glands and hypertrophy of the bronchial smooth muscles. The relationship between inflammation and bronchial hyperresponsiveness is complex and remains unclear. This review article will encompass the current understanding of inflammatory mechanisms in asthma and their association with morphological changes in the airways and the syndrome of bronchial hyperresponsiveness.</p>","PeriodicalId":77589,"journal":{"name":"Plucne bolesti : casopis Udruzenja pneumoftiziologa Jugoslavije = the journal of Yugoslav Association of Phthisiology and Pneumology","volume":"42 1-2","pages":"10-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13369197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N Vasić, B Banićević, L Rajner, G Radosavljević, B Igić
{"title":"[Dressler's syndrome during radiotherapy in bronchial carcinoma].","authors":"N Vasić, B Banićević, L Rajner, G Radosavljević, B Igić","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A case of Dressler's syndrome which has developed in a patient with bronchogenic carcinoma during radiotherapy is presented. Diagnosis is established according to symptomatology, clinical findings, chest X-ray, laboratory analysis and immunological findings. Existence of metastatic deposits in heart is excluded by the method of echocardiography. Short-term cardiologic therapy with antiflogistics is completely sufficient for maintaining the stability of \"cardiologic status\".</p>","PeriodicalId":77589,"journal":{"name":"Plucne bolesti : casopis Udruzenja pneumoftiziologa Jugoslavije = the journal of Yugoslav Association of Phthisiology and Pneumology","volume":"42 1-2","pages":"75-6"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13370762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A computer program for the interpretation of the acid-base status and respiratory gases].","authors":"D Novosel, V Bićanić, S Popović-Grle, F Pavicić","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A computer program for analysing the parameters of the acid-base status and respiratory gases has been designed. The program separates cases which are included into classical picture of certain respiratory, metabolic and mixed disorders. Out of a test series of 200 findings, 93% findings have been accurately interpreted. The program is written in BASIC, translated into machine code and occupies about 25 Kbyte computer memory. The main parts of the program use commands which do not favorize any version of BASIC increasing the program portability to other systems. The classification of respiratory gases and acid-base status was based on the already known facts.</p>","PeriodicalId":77589,"journal":{"name":"Plucne bolesti : casopis Udruzenja pneumoftiziologa Jugoslavije = the journal of Yugoslav Association of Phthisiology and Pneumology","volume":"42 1-2","pages":"113-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13369201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The role bronchial circulation in the etiopathogenesis of increased bronchial reactivity].","authors":"I Grbac, F Knezević, M Basić-Grbac","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The relationship between pathoanatomical changes in bronchial arteries and occurrence of chronic obstructive bronchitis (COB) and bronchial asthma (BA) was studied. Pathoanatomical changes in bronchial arteries were more frequently found in patients with COB and BA than in patients with other bronchopulmonary diseases, i.e. that bronchial circulation in patients with COB and BA is impaired. Due to these findings a theory of vasculary-metabolic explanation of pathogenesis of bronchial hyperresponsiveness is based on hypoperfusion and hypoxia of cellular structures in the bronchial wall. Hypoxia is supposed to be an endogenous change in the bronchial wall which causes bronchial hyperresponsiveness in various exogenous stimulants.</p>","PeriodicalId":77589,"journal":{"name":"Plucne bolesti : casopis Udruzenja pneumoftiziologa Jugoslavije = the journal of Yugoslav Association of Phthisiology and Pneumology","volume":"42 1-2","pages":"16-8"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13369163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}