American journal of veterinary research最新文献

{"title":"Transthoracic impedance in adult Thoroughbred horses is similar to other species.","authors":"Kavita Shroff, Claire Underwood, Darko Stefanovski, Klaus Hopster, JoAnn Slack","doi":"10.2460/ajvr.25.12.0431","DOIUrl":"10.2460/ajvr.25.12.0431","url":null,"abstract":"<p><strong>Objective: </strong>To determine transthoracic impedance (TTI) in adult horses using an exponential biphasic defibrillator and investigate patient and technique factors influencing TTI.</p><p><strong>Methods: </strong>A randomized crossover design with 2 phases was used. Phase 1: TTI was measured in dorsal and lateral recumbency, with and without manual pressure on the electrodes in deceased horses immediately following euthanasia. Phase 2: TTI was measured in dorsal recumbency during inspiration and expiration using anesthetized live horses sourced from 2 terminal studies. Mixed-effects linear regression modeling was performed to assess the influence of patient and technique factors on TTI.</p><p><strong>Results: </strong>19 adult Thoroughbred horses were included. The median TTI for all horses in all conditions was 56 Ω (range, 44 to 133). Eleven horses were enrolled in phase 1 and 8 horses were enrolled in phase 2. Phase 1: Shock 4 TTI (54.2 Ω; 95% CI, 49.0 to 59.3 Ω) was less than shock 1 (67.2 Ω; 95% CI, 55.1 to 79.4 Ω) and shock 2 (71.1 Ω; 95% CI, 54.4 to 87.9 Ω). Phase 2: TTI increased by 0.2% (95% CI, 0.11% to 0.28%) per kilogram of body weight. Terminal study allocation affected TTI.</p><p><strong>Conclusions: </strong>Patient weight and number of shocks influenced TTI. Patient position, manual pressure, and respiratory phase did not affect TTI. Limitations included convenience sampling of horses and the terminal study design.</p><p><strong>Clinical relevance: </strong>TTI in this population is similar to values reported in other species, indicating TTI may not be a primary factor limiting transthoracic cardioversion in the horse.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146257203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent pyuria is associated with shorter progression-free survival in dogs with bladder urothelial carcinoma.","authors":"Sung-Ho Choi, Jin-Kyung Kim, Se-Hoon Kim, Min-Ok Ryu, Kyoung-Won Seo","doi":"10.2460/ajvr.25.12.0438","DOIUrl":"https://doi.org/10.2460/ajvr.25.12.0438","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the association between pyuria and clinical outcomes in dogs.</p><p><strong>Methods: </strong>Data were collected from 2010 through 2025. Pyuria was defined as ≥ 5 WBCs/hpf in urine sediment. Dogs were stratified according to pyuria frequency (0, 1 to 2, or ≥ 3 episodes) and tumor size (< 3 or ≥ 3 cm). Progression-free survival (PFS) and overall survival were analyzed using Kaplan-Meier curves, log-rank tests, and Cox proportional hazards models.</p><p><strong>Results: </strong>51 dogs diagnosed with bladder urothelial carcinoma (UC) were included. When stratified by pyuria frequency, dogs with ≥ 3 episodes had a significantly shorter median PFS than dogs without pyuria (175 vs 365 days), whereas dogs with 1 to 2 episodes did not differ significantly from the nonpyuria group. In the multivariable analysis, ≥ 3 pyuria episodes remained a negative prognostic factor for PFS (hazard ratio, 3.57; 95% CI, 1.27 to 10.04) even after accounting for the total number of urinalyses performed. Dogs with pyuria at initial diagnosis had a shorter median overall survival than the nonpyuria group (353 vs 531 days).</p><p><strong>Conclusions: </strong>Dogs with pyuria at initial diagnosis and frequent pyuria (≥ 3 episodes) during the entire treatment period had shorter PFS than dogs without pyuria.</p><p><strong>Clinical relevance: </strong>This finding parallels observations in human medicine and suggests that pyuria may serve as a clinically useful marker of tumor progression in canine UC.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pilot study to assess feasibility of a computer-assisted surgery system for navigation in the equine cervical spine.","authors":"Samantha A Masca, Jeremiah T Easley, Drew W Koch, Juan M Aragon, Sam E Winston, Andres F Bonilla","doi":"10.2460/ajvr.25.12.0441","DOIUrl":"https://doi.org/10.2460/ajvr.25.12.0441","url":null,"abstract":"<p><strong>Objective: </strong>To validate the accuracy of the Synaptive Medical computer-assisted surgery (CAS) system for navigation in the equine cervical spine, focusing on anatomical targets that require precise localization.</p><p><strong>Methods: </strong>3 equine cervical spine cadavers were used (C1-T1) for an experimental study design. A custom fiducial array was mounted into the dorsal spinous process of C2, with additional fiducial markers distributed for landmark registration. Four participants with varying surgical expertise used the Synaptive Medical CAS system to navigate 9 radiodense pins into 3 anatomical targets, including the intervertebral foramen, articular process joint, and intervertebral disc. Pre- and postprocedural CT scans were used to evaluate pin placement accuracy, defined as the Euclidean distance between planned and achieved points. The procedure duration was also recorded.</p><p><strong>Results: </strong>The mean navigation error between the planned and reached target points was 11.33 ± 11.02 mm. Surgical experience influenced procedure duration; however, it did not significantly affect accuracy. Additionally, our results suggested that placement of a fiducial array into the dorsal spinous process of C2 allowed for successful registration.</p><p><strong>Conclusions: </strong>Use of the Synaptive Medical CAS system for navigation-assisted procedures in the equine cervical spine is feasible and may enhance surgical precision in veterinary applications.</p><p><strong>Clinical relevance: </strong>This study provides insight into the potential integration of CAS into the clinical application of equine cervical spine procedures. This validation supports that CAS can be an option for minimally invasive approaches aimed at reducing clinical complications when accessing the equine cervical spine.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":"1-6"},"PeriodicalIF":1.4,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The neutrophil-to-lymphocyte ratio is associated with disease severity and infectious etiologies of colitis in horses presenting with acute colitis.","authors":"Amanda N Samuels, Niamh Collins, Myriah Albrecht, Rosemary Cuming, Stephen Reed, Diego Gomez, Ramiro Toribio","doi":"10.2460/ajvr.25.12.0447","DOIUrl":"10.2460/ajvr.25.12.0447","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate associations between the neutrophil-to-lymphocyte ratio (NLR), nonsurvival, illness severity, and infectious etiologies.</p><p><strong>Methods: </strong>This was a retrospective multicenter study that included 100 healthy horses and 444 horses presenting with acute diarrhea to 5 equine referral hospitals. Inclusion criteria were diarrhea duration < 48 hours, complete hemograms, and outcome data. Illness severity was assessed using systemic inflammatory response syndrome. The results of pathogen testing for Salmonella spp, equine coronavirus, Clostridium spp, and Neorickettsia risticii/findlayensis were reviewed when available. Data were analyzed using nonparametric statistics and univariate and multivariable logistic regression models.</p><p><strong>Results: </strong>Median NLR [IQR] did not differ between healthy horses (2.06 [1.43 to 2.58]) and horses with colitis (1.93 [0.86 to 3.76]). The NLR was not significantly associated with nonsurvival; however, horses with an NLR < 1.43 demonstrated higher odds of nonsurvival. Horses meeting ≥ 2 systemic inflammatory response syndrome criteria had a lower NLR (1.56 [0.69 to 2.85]) compared with those meeting 0 to 1 criteria (2.54 [1.08 to 4.70]). Horses with an identified infectious cause had lower NLR than those without (1.38 [0.78 to 2.98] vs 2.37 [0.92 to 4.00]), with the lowest NLR observed in equine coronavirus-infected horses (0.73 [0.40 to 1.56]). The NLR alone had limited prognostic performance (area under the curve, 0.51), but multivariable models with NLR had good discriminatory ability (area under the curve, 0.84).</p><p><strong>Conclusions: </strong>While NLR alone is insufficient as a prognostic marker, it may reflect underlying immune dysregulation that contributes to disease severity.</p><p><strong>Clinical relevance: </strong>The NLR is an inexpensive, readily available biomarker that may help clinicians identify horses at risk of severe systemic inflammation and identify infectious colitis when interpreted with other clinical and laboratory findings.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity assessment for veterinary use of human laparoscopic cholecystectomy training models.","authors":"Alexa L Danner, Min Kyong Song, Agnieszka B Frącka, Rachel E Dickson, Boel A Fransson","doi":"10.2460/ajvr.25.07.0264","DOIUrl":"10.2460/ajvr.25.07.0264","url":null,"abstract":"<p><strong>Objective: </strong>To assess validity evidence of 2 commercially available human gallbladder models for canine laparoscopic cholecystectomy (LapChole) training. We hypothesized that both models would display construct validity and would render high face values. The physical model was hypothesized to have higher face validity and the virtual reality (VR) model higher construct validity.</p><p><strong>Methods: </strong>Experimental study. Laparoscopic cholecystectomy-experienced American College of Veterinary Surgeons (ACVS) diplomates and novice surgeons were enrolled. Surgical performance was assessed using a physical model in a box trainer and a VR model at a surgical conference in October 2022 and in a skills laboratory from September 2023 through March 2024. Performances were assessed via predetermined benchmarks and video-recorded for structured assessments by a blinded clinical LapChole-experienced surgeon and a nonblinded novice surgeon. Questionnaires for face value determination were completed by ACVS diplomates after each performance.</p><p><strong>Results: </strong>8 ACVS diplomates and 8 novice surgeons participated. The VR model showed strong correlation between clinical LapChole experience and model metrics, including time (Spearman rho = -0.85), visual analogue scores (rho = 0.79), and operative component rating scales scores (rho = 0.75). The physical model lacked correlation between experience and all model metrics (rho range, -0.02 to 0.21), which precluded construct validity comparisons between models. The VR model had higher face validity than the physical model.</p><p><strong>Conclusions: </strong>Overall, the VR model demonstrated construct validity and superior face value compared to the physical model.</p><p><strong>Clinical relevance: </strong>The VR cholecystectomy model could be considered for veterinary laparoscopic training.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146211959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Telmisartan has antioxidative effects in healthy dogs.","authors":"Kara M Maslyn, Jennifer R Hawley, Craig E Webb, Michael R Lappin","doi":"10.2460/ajvr.25.11.0396","DOIUrl":"10.2460/ajvr.25.11.0396","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the immunomodulatory properties and antioxidative effects of telmisartan in healthy dogs.</p><p><strong>Methods: </strong>8 healthy young-adult mixed-sex purpose-bred research Beagles were used for this study. Dogs were administered telmisartan at 10 mg once daily for 28 days. A CBC, serum cytokine/chemokine panel, and the following antioxidant assays were performed weekly over the course of the study: total antioxidant capacity, Cu-Zn superoxide dismutase, catalase, glutathione reductase, and glutathione peroxidase. Group mean values after starting telmisartan administration were compared to baseline values by repeated-measures ANOVA, with significance defined as P < .05.</p><p><strong>Results: </strong>While significant changes in arterial blood pressure, CBC, or cytokines/chemokines were not detected, telmisartan significantly upregulated the activity of serum superoxide dismutase, serum total antioxidant capacity, and plasma glutathione peroxidase on some sample dates over the 28-day trial when compared to baseline values. In addition, an average weight loss of 4.9% was detected in 7 of 8 dogs between days 0 and 28.</p><p><strong>Conclusions: </strong>Telmisartan has antioxidative effects in healthy dogs.</p><p><strong>Clinical relevance: </strong>This research suggests an additional indication to use this drug in the management of a variety of inflammatory conditions that also have arterial hypertension.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146211972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double J-shaped Kirschner wire fixation provides superior biomechanical stability for feline sacroiliac luxation compared with conventional techniques.","authors":"Sang-Kun Jang, Yookyeong Lee, Sangyul Lee, Jaewon Do, Jeong-Woon Kim, Jun-Sik Cho, Hwi-Yool Kim, Jung-Moon Kim","doi":"10.2460/ajvr.25.11.0422","DOIUrl":"10.2460/ajvr.25.11.0422","url":null,"abstract":"<p><strong>Objective: </strong>To compare the biomechanical stability of 3 fixation techniques for unilateral sacroiliac (SI) luxation using 3-D-printed feline pelvic models.</p><p><strong>Methods: </strong>Eighteen 3-D-printed pelvic models were generated from CT data of a 6.6-kg cat. The study was conducted from July 25 through September 10, 2025. A right SI luxation with ipsilateral pubic and ischial osteotomies was created, and models were fabricated for 3 fixation configurations (n = 6/group): single lag screw with transiliac pinning (SP), double parallel Kirschner wires (DK), and double J-shaped Kirschner wires (DJ). A 3-D-printed femur was toggle pinned to the acetabulum to reproduce stance. Axial compression was applied to the femoral head at 5 mm/min to 15° pelvic rotation. Outcomes included rotational stiffness (primary), maximum load at 10° rotation, and energy absorption.</p><p><strong>Results: </strong>DJ constructs showed approximately 3-fold greater initial rotational stiffness and higher energy absorption than SP and DK. Mean maximum load to 10° rotation was 93.10 N for DJ versus 33.32 N (SP) and 36.59 N (DK). No differences were detected between SP and DK for any parameter.</p><p><strong>Conclusions: </strong>In this ex vivo 3-D-printed model, DJ fixation provided superior rotational stability compared with SP and DK techniques.</p><p><strong>Clinical relevance: </strong>The DJ technique may offer a biomechanically robust alternative for stabilizing feline SI luxation. By avoiding the narrow sacral safe corridor required for lag screw placement, this method may reduce the risk of iatrogenic nerve injury while preserving sacral bone integrity to ensure optimal purchase and minimize the risk of fixation failure during stabilization.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146212027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of the immunomodulatory effects of extracellular vesicles from canine placental and adipose-derived mesenchymal stem cells.","authors":"Jeong-Ho Ha, Jin-Ok Ahn, Jung-Hoon Choi, Sae Hoon Kim, Jin-Young Chung","doi":"10.2460/ajvr.25.12.0426","DOIUrl":"10.2460/ajvr.25.12.0426","url":null,"abstract":"<p><strong>Objective: </strong>To compare the immunomodulatory capacities of canine placenta-derived mesenchymal stem cells (PMSCs; MSCs) and adipose-derived MSCs (ADMSCs) as well as the effects of their extracellular vesicles (EVs) on peripheral blood mononuclear cells (PBMCs).</p><p><strong>Methods: </strong>PMSCs and ADMSCs were isolated and characterized. The PBMCs were cocultured with each isolated MSC. PBMC viability was assessed by trypan blue, and CD4 expression and PBMC proliferation were analyzed by flow cytometry. Inflammatory cytokines in the supernatants were measured using an ELISA. In addition, each type of MSC-derived EV was extracted and incubated with PBMCs. Subsequently, the same analyses used in the MSC experiments were performed. Statistical analyses used SPSS 26 with the significance set at P < .05.</p><p><strong>Results: </strong>In MSC experiments, PMSC group exhibited the highest CD4 expression, and PBMC proliferation was also lowest in PMSC group. PBMC viability was significantly lower in PMSC group. A comparison of the inflammatory cytokine concentrations showed similar IL-2 and IL-10 levels in the groups, whereas TNF-α was significantly lower in PMSC group. In EV experiments, the PMSC EV had a greater ability to inhibit PBMC proliferation than the ADMSC EV, whereas CD4 expression showed no difference. PBMC viability and TNF-α concentration were lowest in PMSC EV group, whereas IL-2 concentration was lowest in ADMSC EV group.</p><p><strong>Conclusions: </strong>PMSCs and their EVs have comparable immunomodulatory effects to ADMSCs, with some statistically significant differences.</p><p><strong>Clinical relevance: </strong>PMSC-derived EVs may represent a potential therapeutic option for immune-mediated conditions.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146211961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep learning cascade networks for segmentation of fluorine-18 sodium fluoride positron emission tomography scans of equine metacarpo- and metatarsophalangeal joints outperform atlas-based method.","authors":"Sergey Anishchenko, Kathryn W Bills, David Beylin, Natalie Beylin, Danielle Beylin, Karina Stepanova, Pavel Stepanov, Mathieu Spriet","doi":"10.2460/ajvr.25.11.0421","DOIUrl":"10.2460/ajvr.25.11.0421","url":null,"abstract":"<p><strong>Objective: </strong>To create a labeled dataset and evaluate a convolutional neural network (CNN) for segmentation of fluorine-18 sodium fluoride PET scans of the equine metacarpo- and metatarsophalangeal joint (fetlock), targeting the third metacarpal bone, proximal phalanx, proximal sesamoid bone(s), and soft tissue.</p><p><strong>Methods: </strong>PET and corresponding CT scans were retrospectively selected from June 2024 through November 2025 using convenience sampling and coregistered to a common reference frame. The coregistered PET-CT scans were manually labeled; the labels were then transferred to PET-only images and used to train a cascade of CNNs with and without data augmentation. Segmentation accuracy was quantified using the Dice coefficient and compared to atlas-based segmentation of the PET-CT scans.</p><p><strong>Results: </strong>A total of 84 scans were collected from 2 facilities. For the test set (n = 8), the minimum, mean, and maximum Dice coefficients computed for all anatomical areas together were 0.85, 0.88, and 0.92, respectively, exceeding the values for atlas-based segmentation of 0.69, 0.80, and 0.87. Analysis of the Dice coefficient by area showed the best CNN segmentation for the third metacarpal bone (mean Dice coefficient (Dmean) = 0.92) and the worst for the medial proximal sesamoid bone (Dmean = 0.82); corresponding atlas-based values were 0.86 and 0.77.</p><p><strong>Conclusions: </strong>CNN-based segmentation of fluorine-18 sodium fluoride PET images of the fetlock outperforms an atlas-based method in both speed and accuracy measured by Dice coefficient. This advancement enables new, previously inaccessible strategies for PET image quantification.</p><p><strong>Clinical relevance: </strong>Accurate and robust segmentation of PET fetlocks enables more accurate analysis and novel insights into lesion characterization.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146211938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinesiology taping with a double-lymphatic pattern reduces canine stifle joint swelling 24 hours after tibial plateau-leveling osteotomy.","authors":"Brittany Ludwig, Amber Ihrke, Katharine Holich, Kathleen Neforos, Robert Eric Heidel","doi":"10.2460/ajvr.25.11.0398","DOIUrl":"10.2460/ajvr.25.11.0398","url":null,"abstract":"<p><strong>Objective: </strong>To assess the effect of kinesiology taping on stifle joint soft tissue swelling in canines 24 hours after tibial plateau-leveling osteotomy (TPLO). The hypothesis was that dogs with kinesiology tape applied postoperatively would have significantly less swelling within 24 hours of surgery compared to those with no kinesiology tape applied.</p><p><strong>Methods: </strong>Canine stifles undergoing TPLO from October 2023 through June 2025 were randomized into 2 groups: a treatment group with kinesiology tape applied in a double-lymphatic pattern to the surgical stifle postoperatively and a control group with no tape applied. Girth measurements were obtained with pressure-sensitive measuring tape at 3 locations (lateral fabella of the femur, joint line, and tibial tuberosity) at 5 time points (immediately before surgical preparation, immediately postoperatively, 3 hours postoperatively, 18 hours postoperatively [18H], and 24 hours postoperatively [24H]).</p><p><strong>Results: </strong>31 canine stifles were split between the treatment (n = 16) and nontreatment (15) groups. The treatment group had significantly less swelling than the control group at the lateral fabella of the femur location at 18H and 24H and at the tibial tuberosity location at 3 hours postoperatively, 18H, and 24H. The kinesiology tape application was well tolerated with no adverse effects.</p><p><strong>Conclusions: </strong>Kinesiology tape applied in a double-lymphatic pattern at the surgical stifle immediately after TPLO reduces soft tissue swelling during the early inflammatory period.</p><p><strong>Clinical relevance: </strong>Kinesiology taping provides a simple, low-cost, noninvasive method to reduce stifle joint soft tissue swelling in the immediate TPLO postoperative period.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146197207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}