American Journal of Tropical Medicine and Hygiene最新文献_第3页

Perspective of Quilombola Communities in Brazil on a Yellow Fever Outbreak and Vaccination. 巴西 Quilombola 社区对黄热病爆发和疫苗接种的看法。

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-04-01 DOI: 10.4269/ajtmh.24-0519

Aline Carralas Queiroz Leão, Sueli F Raymundo, Gabriel Fialkovitz, Luciana Vilas Boas Casadio, Tamar Roemer, Katia Regina Pisciotta, Anna S Levin

{"title":"Perspective of Quilombola Communities in Brazil on a Yellow Fever Outbreak and Vaccination.","authors":"Aline Carralas Queiroz Leão, Sueli F Raymundo, Gabriel Fialkovitz, Luciana Vilas Boas Casadio, Tamar Roemer, Katia Regina Pisciotta, Anna S Levin","doi":"10.4269/ajtmh.24-0519","DOIUrl":"10.4269/ajtmh.24-0519","url":null,"abstract":"In 2016-2019, Brazil faced the most important yellow fever (YF) outbreak in recent decades. In 2019, cases were concentrated in Ribeira Valley, in the southeast region of Brazil, and largely affected rural Quilombola communities, which can trace their origins to escaped, freed, or abandoned slaves in the mid-1800s, and which traditionally practice subsistence agriculture. We aimed to explore aspects of the YF outbreak and vaccination from the perspective of the Quilombola communities. This was a cross-sectional descriptive study conducted in two Quilombola communities in Ribeira Valley (Sapatu and Nhunguara), using an interviewer-administered questionnaire that included both closed and open-ended questions. Thematic reflective analysis principles were applied for qualitative analysis. We adopted a theoretical domains framework to identify and categorize reported facilitators and barriers to YF vaccination. A total of 226 participants were enrolled: 46% male, median age 44 years. Eighty participants reported acute illness during the outbreak; fever, headache, myalgia, and nausea were the most common symptoms. Only eight participants reported laboratory-confirmed YF. Almost all participants (96.5%) reported YF vaccination. Less than two-thirds of the participants were vaccinated before the first case in the Ribeira Valley; over a third were vaccinated after the death of a community leader. The themes were: concerns about the vaccine, difficulty in accessing healthcare, perception of disease risk, knowledge about disease severity, cultural beliefs, and influence of leaders. The outbreak in the Ribeira Valley may have been averted with an understanding of the vaccination decision-making process, influenced by individual, sociocultural, and contextual factors.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serotypes and Antimicrobial Resistance Patterns of Invasive Non-Typhoidal Salmonella in Uganda.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-04-01 DOI: 10.4269/ajtmh.24-0772

John Bosco Kalule, Valeria Nakintu Zalwango, Pauline Kyazike, Samuel Majalija

{"title":"Serotypes and Antimicrobial Resistance Patterns of Invasive Non-Typhoidal Salmonella in Uganda.","authors":"John Bosco Kalule, Valeria Nakintu Zalwango, Pauline Kyazike, Samuel Majalija","doi":"10.4269/ajtmh.24-0772","DOIUrl":"10.4269/ajtmh.24-0772","url":null,"abstract":"Drug-resistant invasive non-typhoidal Salmonella poses a significant challenge to the management of acute febrile illnesses in Uganda. However, the characteristics of invasive non-typhoidal Salmonella strains are not yet well understood. This study aimed to determine the serotypes and antimicrobial resistance patterns of invasive non-typhoidal Salmonella isolates from a local health center in Uganda. Invasive non-typhoidal Salmonella isolates archived over 5 years from febrile patients at a local health center were characterized for serotypes and antimicrobial susceptibility patterns using conventional methods. Among the 80 archived isolates, 18 serotypes of invasive non-typhoidal Salmonella were identified, with Salmonella Typhimurium (42.5%), Salmonella Enteritidis (20%), and Salmonella Haifa (8.8%) being the most prevalent. A total of 81.3% (65/80) of the isolates exhibited resistance to at least one antibiotic, with the highest resistance rates observed for streptomycin (72.5%), trimethoprim-sulfamethoxazole (66.2%), and ampicillin (56.2%). The most common antimicrobial resistance profile, found in 23.1% (15/65) of resistant isolates, was Amp-C-S10-S300-SXT. Notably, 81.5% of the drug-resistant isolates were multi-drug resistant. Invasive non-typhoidal Salmonella in this setting have a high rate of antimicrobial resistance to commonly used antibiotics. Improved treatment guidelines could be adapted for better clinical outcomes.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic Chagas Disease in the Brazilian Amazon: Serological Survey, Clinical Follow-Up, and Associated Risk Factors.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-03-25 DOI: 10.4269/ajtmh.24-0549

Susan Smith-Doria, Laise Kelma Costa Magalhães, Laylah Kelre Costa Magalhães, Suzane Ribeiro Prestes, Alba Regina Jorge Brandão, Emily de Sousa Moura, Elsa Isela Guevara Moctezuma, Monica Regina Hosanahh da Silva E Silva, Katia do Nascimento Couceiro, Yuliana Padrón-Antonio, Victor Irungu Mwangi, Jessica Vanina Ortiz, Leíla Ines Aguiar Raposo Câmara Coelho, Adriano Gomes-Silva, Henrique Silveira, João Marcos Bemfica Barbosa Ferreira, Jorge Augusto de Oliveira Guerra, Maria das Graças Vale Barbosa Guerra

{"title":"Chronic Chagas Disease in the Brazilian Amazon: Serological Survey, Clinical Follow-Up, and Associated Risk Factors.","authors":"Susan Smith-Doria, Laise Kelma Costa Magalhães, Laylah Kelre Costa Magalhães, Suzane Ribeiro Prestes, Alba Regina Jorge Brandão, Emily de Sousa Moura, Elsa Isela Guevara Moctezuma, Monica Regina Hosanahh da Silva E Silva, Katia do Nascimento Couceiro, Yuliana Padrón-Antonio, Victor Irungu Mwangi, Jessica Vanina Ortiz, Leíla Ines Aguiar Raposo Câmara Coelho, Adriano Gomes-Silva, Henrique Silveira, João Marcos Bemfica Barbosa Ferreira, Jorge Augusto de Oliveira Guerra, Maria das Graças Vale Barbosa Guerra","doi":"10.4269/ajtmh.24-0549","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0549","url":null,"abstract":"The prevalence and characteristics of chronic Chagas disease (CCD) in the Amazon Region remain underexplored. This study aimed to describe the challenges encountered during a serological survey and follow-up of CCD, while also highlighting potential risk factors in the Amazon Region. The serological survey involved residents of periurban and rural areas of Manaus in the Brazilian Amazon. All participants were invited to complete a clinical, epidemiological, and demographic questionnaire and provide a blood sample for anti-Trypanosoma cruzi (T. cruzi) IgG tests. A total of 1,845 participants were included, of whom 43 were identified as having presumed CCD, based on having at least two positive serological tests. Only 35 underwent complementary tests, and five had cardiac alterations not consistent with CCD. The main risk factors associated with CCD were age ≥20 years, living in periurban areas, reporting the presence of the insect vector inside the household, entering the forest, consumption of bushmeat, and having undergone blood transfusion. In the Amazon, the population is exposed to the sylvatic T. cruzi life cycle and is unaware of the associated risk factors. The divergent serology results raise doubts about the reliability of the commercial serological tests used for CCD screening in the region. Surveillance for CCD is important in the Amazon.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of Human Papillomavirus and Genotype Correlation with Cervical Lesions at the University Teaching Hospital of Kigali.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-03-25 DOI: 10.4269/ajtmh.24-0760

Evode Mbabazi, Jean Bosco Munyemana, Julienne Mukashema, Emmanuel Bazimaziki, Marie Claire Ndayisaba, Taofeek Tope Adegboyega, Belson Rugwizangoga

{"title":"Prevalence of Human Papillomavirus and Genotype Correlation with Cervical Lesions at the University Teaching Hospital of Kigali.","authors":"Evode Mbabazi, Jean Bosco Munyemana, Julienne Mukashema, Emmanuel Bazimaziki, Marie Claire Ndayisaba, Taofeek Tope Adegboyega, Belson Rugwizangoga","doi":"10.4269/ajtmh.24-0760","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0760","url":null,"abstract":"Cervical cancer remains a major health problem, especially in low- and middle-income countries (LMICs), with human papillomavirus (HPV) infection serving as the primary precursor. Despite global efforts to combat cervical cancer, including vaccination, a critical knowledge gap persists regarding HPV prevalence, genotype distribution, and their correlation with cervical lesions in LMICs. This study has assessed the prevalence of HPV infection, identified the most common HPV genotypes, and evaluated their correlation with cervical lesions at the University Teaching Hospital of Kigali, Rwanda. A total of 473 women were screened for HPV infection, with further evaluation of cervical lesions in HPV-positive women. The overall HPV prevalence was 74 of 473 (15.6%), with the highest concentration among women aged 41-45 years (29.7%). HPV genotypes 16 and 18 were most prevalent (7.6% each). Cyto-histological examination showed 23.6% cancerous lesions and 37.2% benign lesions in women with HPV-positive results. Women with high-risk HPV (HR-HPV) infections had a 2.67-fold increased risk of developing cancerous lesions compared with those with low-risk HPV infections (95% CI: 1.08-6.58, P = 0.033). Notably, 21.6% of HPV-positive women were also HIV-positive, highlighting the coinfection of these two viruses. In conclusion, this study demonstrates a varied distribution of HPV genotypes among Rwandan women and a significant association between HR-HPV types and cervical lesions. These findings emphasize the need for tailored cervical cancer prevention strategies, including targeted surveillance, vaccination, and enhanced screening in Rwanda and similar resource-limited settings.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Microfilaremic Individuals after Mass Drug Treatment with Ivermectin, Diethylcarbamazine, and Albendazole for Lymphatic Filariasis in Papua New Guinea.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-03-25 DOI: 10.4269/ajtmh.24-0382

Joycelyn Salo, Simon Westby, Ronnie Wakol, Nelly Sanuku, Krufinta Bun, Moses Laman, Christopher L King

{"title":"Evaluation of Microfilaremic Individuals after Mass Drug Treatment with Ivermectin, Diethylcarbamazine, and Albendazole for Lymphatic Filariasis in Papua New Guinea.","authors":"Joycelyn Salo, Simon Westby, Ronnie Wakol, Nelly Sanuku, Krufinta Bun, Moses Laman, Christopher L King","doi":"10.4269/ajtmh.24-0382","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0382","url":null,"abstract":"After mass drug administration (MDA) for lymphatic filariasis, which involved a single coadministered dose of ivermectin plus diethylcarbamazine and albendazole (IDA), concerns arose regarding individuals who remained microfilaremic. This situation raised questions about the efficacy of the drugs and whether some individuals had not ingested them. In East New Britain Province, Papua New Guinea (PNG), where 81.7% of the population received IDA, 10 individuals were found to have microfilaremia 12 months after the first round of MDA in an area that had a high baseline of microfilaremia (n = 29 microfilariae [Mf] positive pre-MDA). Of these 10 individuals, 7 reported having taken the IDA medication. When Mf detection was repeated 18 months later, all 10 individuals remained Mf positive. Additionally, three more Mf-positive household members were identified, and they also reported taking the IDA. These Mf-positive individuals were then retreated with IDA under direct observation. At 7 and/or 14 months after retreatment, all initially Mf-positive individuals, except for one, were found to be Mf free. Upon further questioning, it was revealed that all but one individual admitted to not taking the initial MDA. Thus, IDA effectively clears Mf in this region of PNG, and the persistent microfilaremia after MDA is primarily because of individuals failing to take the medications as prescribed.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Calcified Neurocysticercosis: Understanding Dead (Not Necessarily Inactive) Parasites.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-03-18 DOI: 10.4269/ajtmh.24-0446

Christina M Coyle, Javier A Bustos, Oscar H Del Brutto, Hector H Garcia, Theodore E Nash, Vedantam Rajshekhar

引用次数: 0

Combating Child Undernutrition through Community Participation and Action: Reviving Ballabgarh Mixture at Rural Villages of Haryana, India.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-03-18 DOI: 10.4269/ajtmh.24-0649

Ankit Chandra

引用次数: 0

Effect of Socioeconomic Strata and Land Cover on Dengue Hotspots in Medellin, Colombia.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-03-18 DOI: 10.4269/ajtmh.24-0665

Juliana Pérez-Pérez, John Alexander Pulgarin Diaz, Guillermo Rúa-Uribe, Blas Mola-Yudego, Eric Delmelle, Raúl Rojo, Frank Berninger

{"title":"Effect of Socioeconomic Strata and Land Cover on Dengue Hotspots in Medellin, Colombia.","authors":"Juliana Pérez-Pérez, John Alexander Pulgarin Diaz, Guillermo Rúa-Uribe, Blas Mola-Yudego, Eric Delmelle, Raúl Rojo, Frank Berninger","doi":"10.4269/ajtmh.24-0665","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0665","url":null,"abstract":"Despite extensive vector control programs, dengue remains a significant global health challenge, with outbreaks rising worldwide. Effective dengue control requires reinforcing the surveillance systems and using surveillance data to gain a better understanding of dengue dynamics at both spatial and temporal scales. We studied the effect of socioeconomic and land cover on the presence of dengue hotspots in Medellin (Colombia) from 2010 to 2020 and identified recurrent hotspots during severe epidemic (SE), epidemic (E), and non-epidemic (NE) years. We focused on spatial autocorrelation using global and local indicators of spatial association over 40,814 georeferenced dengue cases. Later, we tested if the spatial units identified as hotspots, recurrent hotspots, and non-hotspots were evenly distributed among socioeconomic strata and land cover categories. During the study period, 50% of the dengue cases were concentrated in 26% of the study area. We identified statistically significant hotspots, some recurring for up to 7 years with their spatial patterns differing between SE, E, and NE years, even though some recurred over time. Recurrent hotspots predominantly occurred in low-medium socioeconomic strata and were absent in the highest strata. Also, they predominated in human-made structures. The interaction between socioeconomic factors, land cover, and potentially, the vector presence seems to explain the spatial variation of dengue epidemics and their recurrent hotspots in Medellin.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends in Post-Kala-Azar Dermal Leishmaniasis in Sudan: Cases, Ethnic Distribution, and Recovery.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-03-18 DOI: 10.4269/ajtmh.24-0602

Osama S Osman, Mohamed E Hamid

{"title":"Trends in Post-Kala-Azar Dermal Leishmaniasis in Sudan: Cases, Ethnic Distribution, and Recovery.","authors":"Osama S Osman, Mohamed E Hamid","doi":"10.4269/ajtmh.24-0602","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0602","url":null,"abstract":"Post-kala-azar dermal leishmaniasis (PKDL) is a neglected tropical disease that can develop after treatment of leishmaniasis. It causes significant health risks and serves as a reservoir, perpetuating transmission. Current information on PKDL characteristics is crucial for effective disease management and control. This study aimed to describe clinical and epidemiological characteristics of PKDL patients in eastern Sudan. A retrospective cross-sectional study was conducted on suspected PKDL patients (N = 37) at a tertiary hospital in eastern Sudan. Blood samples were tested for anti-rK39 antibodies to confirm the diagnosis of the disease. Demographic, clinical, and epidemiological data of the PKDL patients were gathered and analyzed. Most PKDL cases (69.4%) came from specific locations involving one ethnic group (94.6%), mainly affecting young males (54.1%). A family history of PKDL was noted in only 27.0% of cases; 51.4% developed PKDL within 1 month after visceral leishmaniasis (VL) treatment. Most cases (56.8%) were grade 1 (a low level of parasitic load), predominantly featuring macular (51.4%), papular (18.9%), and nodular (13.5%) lesions. All patients had skin rashes; 91.9% exhibited no fever, and 29.7% reported itching. Lesions appeared within a month after VL treatment, with most patients recovering spontaneously within 3-18 months. PKDL was particularly prevalent in specific regions and ethnic groups, namely the Masaleet and Dago tribes. These findings can enhance PKDL understanding and management in the region.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mark-Release-Recapture of Packed and Shipped Aedes aegypti with Wolbachia: Implications for Conducting Remote Incompatible Insect Technique Programs.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-03-18 DOI: 10.4269/ajtmh.24-0262

Johanna R Ohm, Amy Lynd, Austin McGowan, Angel Cupid, Vernessa Bellot, James Q Le, Evdoxia Kakani, Josh Livni, Jacob E Crawford, Bradley J White

{"title":"Mark-Release-Recapture of Packed and Shipped Aedes aegypti with Wolbachia: Implications for Conducting Remote Incompatible Insect Technique Programs.","authors":"Johanna R Ohm, Amy Lynd, Austin McGowan, Angel Cupid, Vernessa Bellot, James Q Le, Evdoxia Kakani, Josh Livni, Jacob E Crawford, Bradley J White","doi":"10.4269/ajtmh.24-0262","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0262","url":null,"abstract":"Male mosquitoes containing the endosymbiont Wolbachia (Wb+) can be used as a tool to suppress wild mosquito populations through a technique termed incompatible insect technique (IIT). IIT programs reduce wild mosquitoes via incompatible matings between released males and wild females to reduce the number of viable offspring produced in the next generation. Successful programs rely on regular release of incompatible males to outcompete wild males for female mates. Past IIT programs have relied on local production of Wb+ males to support regular releases of incompatible males. Here, we evaluated the survival and dispersal of packed and shipped Wb+ Aedes aegypti males in mark-release-recapture studies at a release site in the British Virgin Islands (BVI), separated by over 3,600 miles from the centralized production facility. Released mosquitoes were recaptured using BG-Sentinel 2 traps collected daily for up to 7 days after release. Wb+ male mosquitoes packed and shipped from a centralized production facility performed similarly to males that were locally reared in the BVI in survival, dispersal, and recapture rates. Our results support the conclusion that packing and shipping live Wb+ male mosquitoes does not impact their ability to survive and disperse in release sites and suggests that IIT mosquito control programs can feasibly be conducted nearly anywhere in the world without the need for local mosquito production facilities.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0