Anaesthesia最新文献

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A pilot multicentre randomised clinical trial to determine the effect of a pharmacist-partnered opioid tapering intervention before total hip or knee arthroplasty. 一项试验性多中心随机临床试验,旨在确定在全髋关节或膝关节置换术前由药剂师协助进行阿片类药物减量干预的效果。
IF 7.5 1区 医学
Anaesthesia Pub Date : 2024-07-31 DOI: 10.1111/anae.16390
Shania Liu, Asad E Patanwala, Jennifer Stevens, Jonathan Penm, Justine Naylor
{"title":"A pilot multicentre randomised clinical trial to determine the effect of a pharmacist-partnered opioid tapering intervention before total hip or knee arthroplasty.","authors":"Shania Liu, Asad E Patanwala, Jennifer Stevens, Jonathan Penm, Justine Naylor","doi":"10.1111/anae.16390","DOIUrl":"https://doi.org/10.1111/anae.16390","url":null,"abstract":"<p><strong>Background: </strong>Opioid analgesic use before total hip or knee arthroplasty has been associated with worse postoperative outcomes. This pilot study aimed to examine the feasibility of a telehealth-based pharmacist-partnered opioid tapering intervention before elective primary hip or knee arthroplasty and its potential effectiveness compared with usual care.</p><p><strong>Methods: </strong>This study was conducted at seven hospitals in New South Wales, Australia. Eligible patients were those aged ≥ 18 years, scheduled to undergo primary hip or knee arthroplasty for osteoarthritis and taking opioid analgesics pre-operatively. The intervention group participated in an opioid tapering telehealth service, a partnership between a pharmacist and general practitioner, for 3 months pre-operatively up to the day of surgery, while the control group received usual care. The primary outcomes of the study were to investigate the feasibility of the intervention (i.e. adherence to treatment) and potential effectiveness in decreasing baseline daily opioid dose by > 50% before surgery.</p><p><strong>Results: </strong>Between December 2021 and June 2023, 70 patients were recruited and assigned randomly to the intervention group (n = 35) or control group (n = 35). Baseline characteristics were similar between groups. Thirty patients in each group completed their allocated treatment. All patients allocated to the intervention group completed at least one appointment with a pharmacist, with the median (IQR [range]) being 2 (1-4 [1-6]) appointments. The number of patients who successfully decreased their baseline daily opioid dose by ≥ 50% before surgery was 27/30 in the intervention group compared with 5/30 in the usual care group (p < 0.001).</p><p><strong>Conclusions: </strong>The findings of this pilot study support the feasibility of a telehealth-delivered, pharmacist-partnered opioid tapering service for patients scheduled for primary hip or knee arthroplasty. A broader multicentre study to examine the effectiveness of this intervention on clinical outcomes is warranted.</p>","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141858832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Re-exploration following caesarean birth: a prospective national case-control study using the United Kingdom Obstetric Surveillance System (UKOSS) data collection system. 剖腹产后再次剖腹产:利用英国产科监测系统(UKOSS)数据收集系统进行的前瞻性全国病例对照研究。
IF 7.5 1区 医学
Anaesthesia Pub Date : 2024-07-31 DOI: 10.1111/anae.16392
Kailash Bhatia, Malachy Columb, Marian Knight, Sarah Vause
{"title":"Re-exploration following caesarean birth: a prospective national case-control study using the United Kingdom Obstetric Surveillance System (UKOSS) data collection system.","authors":"Kailash Bhatia, Malachy Columb, Marian Knight, Sarah Vause","doi":"10.1111/anae.16392","DOIUrl":"https://doi.org/10.1111/anae.16392","url":null,"abstract":"<p><strong>Background: </strong>Re-exploration following caesarean birth and the associated maternal morbidity has not been investigated in the UK. Our aims were to determine the national incidence and identify the associated risk factors.</p><p><strong>Methods: </strong>We conducted a prospective observational case-control study across 194 UK consultant-led maternity units in women whose caesarean birth was complicated by a re-exploration. Independent factors for re-exploration were analysed using multivariable multi-level mixed effects logistic regression.</p><p><strong>Results: </strong>Over the study period (1 June 2021 and 31 May 2022) 238,423 caesarean births were recorded across the UK of which 187 women underwent re-exploration, giving an incidence of one re-exploration per 1282 caesarean births (95%CI 1:1099-1:1471). Haemorrhage (124/187, 66.3%) and sepsis (31/187, 16.6%) were the most common findings at re-exploration. Median (IQR [range]) time interval to re-exploration following the caesarean birth was 1 (0-4 [0-28]) day. Mechanical ventilation was required in 34 (18.6%) women, cardiac arrest was reported in 5 (2.7%) and 3 (1.6%) women died. Independent preceding factors associated with a re-exploration included: receipt of blood transfusion (adjusted OR (95%CI) 8.25 (2.66-25.61)); use of a general anaesthetic (adjusted OR (95%CI) 3.33 (1.61-6.88)); pre-eclampsia (adjusted OR (95%CI) 3.27 (1.55-6.91)); black ethnicity (adjusted OR (95%CI) 3.14 (1.39-7.11)); postpartum haemorrhage (adjusted OR (95%CI) 2.82 (1.81-4.37)); use of anticoagulants or antiplatelet drugs pre-caesarean birth (adjusted OR (95%CI) 2.26 (1.35-3.81)); and emergency caesarean birth (adjusted OR (95%CI) 1.89 (1.01-3.57)).</p><p><strong>Conclusion: </strong>Re-exploration following caesarean birth in the UK is uncommon but is associated with significant maternal morbidity and mortality. These study findings will help guide informed consent and encourage appropriate surveillance of high-risk women postpartum.</p>","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141858833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Time to motor block regression after neuraxial anaesthesia for caesarean delivery: a retrospective, cohort study 剖腹产神经麻醉后运动阻滞消退的时间:一项回顾性队列研究。
IF 7.5 1区 医学
Anaesthesia Pub Date : 2024-07-29 DOI: 10.1111/anae.16400
William Shippam, Simon Massey, Kathyrn Clark, Luc Saulnier, Anthony Chau
{"title":"Time to motor block regression after neuraxial anaesthesia for caesarean delivery: a retrospective, cohort study","authors":"William Shippam,&nbsp;Simon Massey,&nbsp;Kathyrn Clark,&nbsp;Luc Saulnier,&nbsp;Anthony Chau","doi":"10.1111/anae.16400","DOIUrl":"10.1111/anae.16400","url":null,"abstract":"&lt;p&gt;Prolonged motor block regression following neuraxial anaesthesia should prompt careful evaluation for serious postpartum neurological injuries and complications such as vertebral column haematoma. The ability to perform straight leg raise against gravity 4 h after neuraxial anaesthesia has been recommended as a time threshold to trigger review [&lt;span&gt;1&lt;/span&gt;]. However, using this time threshold, we observed a large number of our patients required review, resulting in a labour-intensive process that we found difficult to sustain [&lt;span&gt;2&lt;/span&gt;]. One possible explanation for the excessive number of triggers may be related to the increased local anaesthetic doses used at our institution, a practice that began during the COVID-19 pandemic and has continued. We hypothesised that the median time to motor block regression after spinal or epidural anaesthesia is &gt; 4 h. To test this, we conducted a retrospective cohort study to characterise the duration of sensory and motor block regression following neuraxial anaesthesia for caesarean delivery (Fig. 1).&lt;/p&gt;&lt;p&gt;The study was deemed a quality improvement project and research ethics committee approval was not required. Data from 200 patients receiving intrathecal (n = 100, 0.75% hyperbaric bupivacaine with fentanyl 10–15 mcg and morphine 100 mcg) and epidural (n = 100, lidocaine 2% with adrenaline 1:200,000, fentanyl 50–100 mcg and morphine 1.5–2 mg) anaesthesia for elective or emergency caesarean deliveries were retrospectively collected from patient records between December 2021 and February 2022. Sensory and motor evaluations were performed as per our standard institutional protocol. The primary outcome was median time to motor block regression, defined as time of intrathecal injection or epidural top-up, to time of recovery of straight leg raising, analysed using Kaplan–Meier curves with hazard ratio obtained via the Mantel–Haenszel method. Secondary outcomes were median time to motor block regression stratified by intrathecal dose, median time to ambulation and median time to S3 dermatome recovery of sensation to cold.&lt;/p&gt;&lt;p&gt;Results are presented in Table 1. The maximum time to straight leg raising in outliers was greater with increasing intrathecal dose used, although this study was not powered to examine differences between groups. For sensory block regression, there were significant outliers; four patients in the intrathecal group took 15–21 h for complete motor block regression and four patients in the epidural group took 16–27 h for complete sensory block regression. There were no cases of postpartum neuropathy.&lt;/p&gt;&lt;p&gt;Using 12.5 mg intrathecal 0.5% hyperbaric bupivacaine, Chapron et al. found the median (IQR [range]) time to complete motor block resolution was 3.7 (3.2–4.2 [1.5–5.0]) h [&lt;span&gt;3&lt;/span&gt;]. However, the use of a different dose, concentration and motor block endpoint makes it difficult to directly compare our findings with previous studies. Additionally, there are likely other c","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anae.16400","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First-attempt awake tracheal intubation success rate using a hyperangulated unchannelled videolaryngoscope vs. a channelled videolaryngoscope in patients with anticipated difficult airway: a randomised controlled trial. 在预计气道困难的患者中使用超切口无通道视频喉镜与有通道视频喉镜的首次尝试清醒气管插管成功率:随机对照试验。
IF 7.5 1区 医学
Anaesthesia Pub Date : 2024-07-29 DOI: 10.1111/anae.16389
Manuel Taboada, Jorge Fernández, Ana Estany-Gestal, Inma Vidal, Laura Dos Santos, Carmen Novoa, Alejandra Pérez, Javier Segurola, Edgar Franco, Julia Regueira, Paula Mirón, Rosa Sotojove, Julio Cortiñas, Agustín Cariñena, Marcos Peiteado, Alfonso Rodríguez, Teresa Seoane-Pillado
{"title":"First-attempt awake tracheal intubation success rate using a hyperangulated unchannelled videolaryngoscope vs. a channelled videolaryngoscope in patients with anticipated difficult airway: a randomised controlled trial.","authors":"Manuel Taboada, Jorge Fernández, Ana Estany-Gestal, Inma Vidal, Laura Dos Santos, Carmen Novoa, Alejandra Pérez, Javier Segurola, Edgar Franco, Julia Regueira, Paula Mirón, Rosa Sotojove, Julio Cortiñas, Agustín Cariñena, Marcos Peiteado, Alfonso Rodríguez, Teresa Seoane-Pillado","doi":"10.1111/anae.16389","DOIUrl":"https://doi.org/10.1111/anae.16389","url":null,"abstract":"<p><strong>Introduction: </strong>There is uncertainty about the optimal videolaryngoscope for awake tracheal intubation in patients with anticipated difficult airway. The use of channelled and unchannelled videolaryngoscopy has been reported, but there is a lack of evidence on which is the best option.</p><p><strong>Methods: </strong>We conducted a randomised clinical trial to compare the efficacy of the C-MAC D-Blade® vs. Airtraq® in adult patients (aged ≥ 18 y) scheduled for elective or emergency surgery under general anaesthesia with anticipated difficult airway who required awake tracheal intubation under local anaesthesia and conscious sedation. The primary endpoint was the first-attempt tracheal intubation success rate. Secondary outcomes included the overall success rate; number of tracheal intubation attempts; Cormack and Lehane glottic view; level of difficulty (visual analogue score); patient discomfort (visual analogue score); and incidence of complications.</p><p><strong>Results: </strong>Ninety patients (70/90 male (78%); mean (SD) age 65 (12) y) with anticipated difficult airways were randomly allocated to C-MAC D-Blade or Airtraq videolaryngoscopy. First-attempt successful tracheal intubation rate was higher in patients allocated to the C-MAC D-Blade group compared with those allocated to the Airtraq group (38/45 (84%) vs. 28/45 (62%), respectively; p = 0.006). The proportion of patients' tracheas that were intubated at the second and third attempt was 4/45 (9%) and 3/45 (7%) in those allocated to the C-MAC D-Blade group compared with 14/45 (31%) and 1/45 (2%) in those allocated to the Airtraq group (p = 0.006). There was no significant difference in overall tracheal intubation success rate (C-MAC D-Blade group 45/45 (100%) vs. Airtraq group 43/45 (96%), p = 0.494).</p><p><strong>Discussion: </strong>In patients with anticipated difficult airway, first-attempt awake tracheal intubation success rate was higher with the C-MAC D-Blade compared with Airtraq laryngoscopy. No difference was found between the two videolaryngoscopes in overall tracheal intubation success rate.</p>","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141791703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tracheal tube introducer-associated airway trauma: a systematic review 气管导管相关气道创伤:系统性综述。
IF 7.5 1区 医学
Anaesthesia Pub Date : 2024-07-28 DOI: 10.1111/anae.16379
Adam J. Boulton, Edward Smith, Ambreen Yasin, Joseph Moreton, Cyprian Mendonca
{"title":"Tracheal tube introducer-associated airway trauma: a systematic review","authors":"Adam J. Boulton,&nbsp;Edward Smith,&nbsp;Ambreen Yasin,&nbsp;Joseph Moreton,&nbsp;Cyprian Mendonca","doi":"10.1111/anae.16379","DOIUrl":"10.1111/anae.16379","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Tracheal tube introducers are recommended in airway management guidelines and are used increasingly as videolaryngoscopy becomes more widespread. This systematic review aimed to summarise the published literature concerning tracheal tube introducer-associated airway trauma.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>PubMed, EMBASE and CINAHL databases were searched using pre-determined criteria. Two authors independently assessed search results and performed data extraction and risk of bias assessments.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We included 16 randomised controlled trials and five observational studies involving 10,797 patients. There was heterogeneity in patient characteristics, airway manipulation, and airway trauma definition and measurement. One study investigated hyperangulated videolaryngoscopy. The standard stylet was the most commonly reported introducer, followed by bougie and stylets with additional features such as video or lighted tip. Airway trauma resulted in low harm and most frequently involved injuries to the upper airway, followed by laryngeal and tracheobronchial injuries. Eighteen studies were comparative and reported a reduction in airway trauma incidence when an introducer was used, with the exception of the standard stylet. Median (IQR [range]) pooled incidence of airway trauma associated with standard stylets was 13.1% (4.2–31.4 [0.5–79.2])% and with bougies was 5.4% (0.4–49.9 [0.0–68.0])%. The risk of bias of included studies was variable and many randomised trials were found to be at high risk due to non-robust measurement of the outcome.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Stylets might be associated with an increased risk of airway trauma compared with other devices or when no stylet was used, though the quality of evidence is modest. However, other introducers appear to be safe and reduce the risk of airway trauma.</p>\u0000 </section>\u0000 </div>","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anae.16379","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Not all tracheal tube introducers are created equal 并非所有气管导管都是一样的。
IF 7.5 1区 医学
Anaesthesia Pub Date : 2024-07-28 DOI: 10.1111/anae.16374
Ursula Galway, Basem B. Abdelmalak
{"title":"Not all tracheal tube introducers are created equal","authors":"Ursula Galway,&nbsp;Basem B. Abdelmalak","doi":"10.1111/anae.16374","DOIUrl":"10.1111/anae.16374","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges and support for workers coming back to work after maternity leave 为产假后重返工作岗位的工人提供挑战和支持
IF 7.5 1区 医学
Anaesthesia Pub Date : 2024-07-25 DOI: 10.1111/anae.16393
Parshant Mittal, Mayank Kulshrestha
{"title":"Challenges and support for workers coming back to work after maternity leave","authors":"Parshant Mittal,&nbsp;Mayank Kulshrestha","doi":"10.1111/anae.16393","DOIUrl":"10.1111/anae.16393","url":null,"abstract":"<p>Successful return to work after maternity leave is a global problem in all areas of work, including healthcare, as highlighted recently by Allen et al. [<span>1</span>]. In June 2020, the UK General Medical Council commissioned community research for induction of doctors, including those returning to work, and showed that the induction process was sometimes overlooked as employers were not aware of changes that might have occurred [<span>2</span>]. Safe return after maternity leave needs to be addressed [<span>3</span>]. A smooth induction should include a personal development plan to focus on areas of concern; a brief period of observation or shadowing; and appropriate measures to safeguard patient safety. Special return-to-work courses may help with this process. For workers who are breastfeeding, facilities to express and store milk, and rest areas should be provided [<span>3</span>].</p><p>According to NHS England around 10% of doctors in training posts are on pre-approved time-out from training for a long duration [<span>4</span>]. To support their re-joining, the NHS has a SuppoRTT programme (Supporting Return To Training) which can be accessed via local Health Education England offices [<span>4</span>]. This programme focuses on an enhanced supervised period, funding supernumerary working, refresher courses and funding for other courses as per individual needs. Some offices also provide Keeping In Touch (KiT) days after maternity leave and Shared Parental Leave In Touch (SPLiT) days to allow for attendance at relevant courses and meetings. Small amounts of funding are also provided to cover childcare during those periods [<span>4</span>].</p><p>Induction after maternity leave can be a daunting process and policies should be in place even before going on leave. Rotas need to be tailored to individual needs and modified gradually for full-time work. As the NHS is facing workforce challenges, smooth and planned induction can help to motivate a person's return to work at their full potential. Childcare and breastfeeding facilities should be in place to support the emotional health of the parents. Poor support after retuning back to practice can lead to adverse effects on mental health and loss of career ambition.</p>","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anae.16393","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141754531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
System leaks and the loss of sevoflurane 系统泄漏和七氟烷损失。
IF 7.5 1区 医学
Anaesthesia Pub Date : 2024-07-23 DOI: 10.1111/anae.16386
Alain F. Kalmar, An Teunkens, Steffen Rex, Hugo Vereecke, Harold Mulier, Michel M. R. F. Struys
{"title":"System leaks and the loss of sevoflurane","authors":"Alain F. Kalmar,&nbsp;An Teunkens,&nbsp;Steffen Rex,&nbsp;Hugo Vereecke,&nbsp;Harold Mulier,&nbsp;Michel M. R. F. Struys","doi":"10.1111/anae.16386","DOIUrl":"10.1111/anae.16386","url":null,"abstract":"<p>We thank Tokumine et al. for the valuable insights on the potential contribution of system leaks on the loss of sevoflurane [<span>1</span>]. If, as their findings convincingly suggest, the system leaks should be considered negligible, the question remains as to how the missing sevoflurane escaped the system [<span>2</span>]. Given that substantially higher systemic absorption is unlikely, incomplete capture by CONTRAfluran™ (Baxter International, Deerfield, IL, USA) appears to be one of the few plausible explanations.</p><p>Since the interaction between activated carbon and sevoflurane is driven by non-covalent forces (primarily Van der Waals interactions which are reversible) it is plausible that, particularly under high fresh gas flow and low partial pressure of sevoflurane, there is incomplete capture or even dissociation and re-release of sevoflurane. It is noteworthy that, to enable the recycling of the adsorbed volatile anaesthetics, the substrate of CONTRAfluran must be selected such that the molecular binding is not excessively strong, allowing desorption at a sufficiently low temperature to avoid degradation of the sevoflurane molecules [<span>3</span>].</p><p>In our study protocol, we aimed to achieve maximum elimination of sevoflurane with the patients' trachea intubated. Immediately after stopping sevoflurane administration, we maintained a fresh gas flow of 9 l.min<sup>-1</sup> for a considerable duration until the patient was responsive. A certain amount of desorption and re-release may have occurred during this phase. A possible recommendation could be to use a lower fresh gas flow during the elimination phase of volatile anaesthesia to minimise desorption. This reflects that there is still considerable room for further optimisation of the technology.</p>","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anae.16386","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141750847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peri-operative care of transgender and gender-diverse individuals: guidance for clinicians and departments 变性人和不同性别者的围手术期护理:临床医生和科室指南。
IF 7.5 1区 医学
Anaesthesia Pub Date : 2024-07-23 DOI: 10.1111/anae.16378
Stuart Edwardson, Luke Flower, Erik Fawcett, Rebecca Medlock, Ada S. Cheung, Kamilla Kamaruddin, Victoria L. McCormack, Seema Agarwal
{"title":"Peri-operative care of transgender and gender-diverse individuals: guidance for clinicians and departments","authors":"Stuart Edwardson,&nbsp;Luke Flower,&nbsp;Erik Fawcett,&nbsp;Rebecca Medlock,&nbsp;Ada S. Cheung,&nbsp;Kamilla Kamaruddin,&nbsp;Victoria L. McCormack,&nbsp;Seema Agarwal","doi":"10.1111/anae.16378","DOIUrl":"10.1111/anae.16378","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The objective of this document is to guide best practice to ensure the safety and dignity of transgender and gender-diverse people in the peri-operative period. While transgender and gender-diverse people may have specific health needs in relation to gender dysphoria, their health requirements go beyond their gender identity. Most doctors will provide care to someone who is transgender or gender-diverse at some stage in their career. It is therefore important that all anaesthetists are educated on specific considerations when caring for these patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A working party was assembled consisting of individuals with experience in direct clinical care of the relevant patient group, those who have expertise in endocrinology and gender-affirming hormones, educators on the topic of transgender and gender-diverse healthcare, and authors of both cisgender and transgender identities. After discussion among the working party, targeted searches of literature were undertaken.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The authors initially came up with a list of over 25 recommendations which was subsequently revised to a list of 15 recommendations after further review by the working party. These included airway assessment and management; management of hormonal therapy; relevant issues in obstetric anaesthesia; and hospital infrastructure and processes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This document provides the first guidance produced to advise on best practice to ensure the safety and dignity of trans and gender-diverse individuals in the peri-operative period.</p>\u0000 </section>\u0000 </div>","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anae.16378","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141750846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to “Prospective comparison of three methods for detecting peri-operative neurocognitive disorders in older adults undergoing cardiac and non-cardiac surgery” 对 "检测接受心脏和非心脏手术的老年人围手术期神经认知障碍的三种方法的前瞻性比较 "的更正。
IF 7.5 1区 医学
Anaesthesia Pub Date : 2024-07-22 DOI: 10.1111/anae.16387
{"title":"Correction to “Prospective comparison of three methods for detecting peri-operative neurocognitive disorders in older adults undergoing cardiac and non-cardiac surgery”","authors":"","doi":"10.1111/anae.16387","DOIUrl":"10.1111/anae.16387","url":null,"abstract":"<p>van Zuylen ML, Kampman JM, Turgman O, et al. Prospective comparison of three methods for detecting peri-operative neurocognitive disorders in older adults undergoing cardiac and non-cardiac surgery. <i>Anaesthesia</i> 2023; 78: 577–586. https://doi.org/10.1111/anae.15965.</p><p>In the article cited above, it has come to our attention that an inadvertent data processing error occurred during the merging of our datasets. Specifically, the column containing preoperative BNT-30 test scores was erroneously duplicated into the postoperative speed and attention cognitive domain column. Consequently, several erroneous outcomes were reported, including an inflated number of patients diagnosed with peri-operative neurocognitive disorders (PNCD).</p><p>After discovering this error, we repeated all statistical analyses with the correct data, taking utmost care to rectify the erroneous data. Despite the revised findings indicating a lower incidence of PNCD, all conclusions drawn in the original manuscript remain unchanged. The lower PNCD incidence remains appropriate for the population studied.</p><p>Revised supplementary materials have been posted to the original article; text corrections are outlined below. Corrected versions of Table 2 and Figure 3 appear following the text corrections.</p><p>Page 577, Summary:</p><p>“Postoperative Modified Telephone Interview for Cognitive Status and cognitive domain scores were very weakly to weakly correlated (r = 0.09–0.36).”</p><p>should be changed to “Postoperative Modified Telephone Interview for Cognitive Status and cognitive domain scores were very weakly to weakly correlated (r = <b>0.10</b>–0.36).”</p><p>Page 580, Results:</p><p>“Postoperative Modified Telephone Interview for Cognitive Status scores showed very weak to weak correlations with postoperative scores on the complete neuropsychological assessment (r = 0.09–0.36).”</p><p>should be changed to “Postoperative Modified Telephone Interview for Cognitive Status scores showed very weak to weak correlations with postoperative scores on the complete neuropsychological assessment (r = <b>0.10</b>–0.36).”</p><p>Page 582:</p><p>“showed moderate to good test–retest reliability, except for the ‘speed and attention’ cognitive domain (see online Supporting Information Appendix S10).”</p><p>should be changed to “showed moderate to good test–retest <b>reliability (see online</b> Supporting Information Appendix S10).”</p><p>“Of the included patients, 21 (27%) had postoperative neurocognitive disorders”.</p><p>should be changed to “Of the included patients, <b>14 (18%)</b> had postoperative neurocognitive disorders”.</p><p>Page 583:</p><p>“The exceptions to this were pre-operative Montreal Cognitive Assessment scores, which were higher in the postoperative neurocognitive disorder group (p = 0.032) and the ‘memory’ cognitive domain, which was higher in the postoperative neurocognitive disorders group (p = 0.006).”</p><p>Should be changed to “The exceptions to this were ","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anae.16387","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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