Anaesthesia最新文献

{"title":"Time to surgery as a prehabilitation window: insights from United States Medicare data","authors":"Kailin Xu, Steve Kwon, Chan Mi Park, Dae Hyun Kim","doi":"10.1111/anae.16675","DOIUrl":"https://doi.org/10.1111/anae.16675","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"56 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144503563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional anaesthesia for awake children: a reply","authors":"Olivier Maupain","doi":"10.1111/anae.16668","DOIUrl":"https://doi.org/10.1111/anae.16668","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"67 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144503571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Within-patient comparisons of direct and videolaryngoscopic view during routine use of a C-MAC® Macintosh videolaryngoscope","authors":"Christopher J. Thorne, Robert Penders, Matthew Hillier, Fiona E. Kelly, Tim M. Cook","doi":"10.1111/anae.16670","DOIUrl":"10.1111/anae.16670","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"80 8","pages":"1002-1003"},"PeriodicalIF":7.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anae.16670","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144500818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between postoperative anaemia and specific drivers of unplanned readmission","authors":"Kirstie Evans, Tim Makar, Lachlan F. Miles","doi":"10.1111/anae.16677","DOIUrl":"10.1111/anae.16677","url":null,"abstract":"<p>Unplanned readmissions after major surgery place a substantial burden on healthcare systems, highlighting the need to identify their causes and develop targeted prevention strategies. We previously identified the most common reasons for readmission after major surgery, with infection and cardiovascular complications the two leading causes [<span>1</span>]. In addition, we found that a lower discharge haemoglobin concentration was associated with an increased risk of readmission [<span>1</span>]. However, we did not explore if there was an association between these two results. Given known associations between anaemia and worse outcomes in conditions like heart failure [<span>2</span>], we aimed to explore whether postoperative anaemia is associated with the most common causes of readmission after major surgery.</p><p>We reanalysed our previously described database of 14,632 patients who had undergone major surgery with adjudicated readmissions [<span>1</span>]. We aimed to determine if there was an association between discharge haemoglobin concentration and each of the top five categories of readmission identified in our previous study: infection; cardiovascular; gastrointestinal; respiratory; and musculoskeletal (online Supporting Information Table S1). Ethics approval was granted with a waiver of informed consent from the Austin Health Human Research Ethics Committee.</p><p>For each readmission category, we applied univariable and multivariable binomial logistic regression models. Discharge haemoglobin concentration was maintained as a linear independent variable for ease of interpretation. Covariates were those previously selected a priori. Restricted cubic splines were used for the other continuous covariates. The number of knots was selected between 3 and 6 using an iterative process to minimise Akaike information criterion for each of the multivariable models.</p><p>We found that a decrease in discharge haemoglobin concentration was associated with increased odds of readmission due to infection (p = 0.002) and cardiovascular complications (p = 0.011) (Table 1). No significant relationship was identified with readmissions due to gastrointestinal, respiratory and musculoskeletal causes.</p><p>For every 10 g.l<sup>-1</sup> decrease in discharge haemoglobin concentration, we found a 12% increase in the odds of readmission due to infection. From our previous study, we found that most unplanned readmissions driven by infection are due to wound complications (232/2048, 11%) [<span>1</span>]. Deep surgical site infections (60/2048, 3%) and cellulitis (29/2048, 1%) were the next leading causes of infectious readmissions. Similarly, we found a 12% increase in the odds of cardiovascular causes of readmission for every 10 g.l<sup>-1</sup> decrease in discharge haemoglobin concentration. The leading cause of cardiovascular readmissions identified in our previous study was heart failure (107/2048, 5%), followed by arrhythmia (69/2048, 3%) and thromboe","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"80 8","pages":"1000-1001"},"PeriodicalIF":7.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anae.16677","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144500837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravenous lidocaine with propofol-based sedation for colonoscopy.","authors":"Xuemiao Tang, Qiang Fu","doi":"10.1111/anae.16671","DOIUrl":"https://doi.org/10.1111/anae.16671","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weathering the storm: the role of supervisors in resident anaesthetist wellbeing","authors":"Krishma Adatia","doi":"10.1111/anae.16669","DOIUrl":"https://doi.org/10.1111/anae.16669","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"22 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144503531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rates of discontinuation and non-publication of regional anaesthesia clinical trials: a registry-based cross-sectional analysis","authors":"Adam Khan, Ethan Black, Andrew Tran, Tag Harris, Matt Vassar","doi":"10.1111/anae.16674","DOIUrl":"10.1111/anae.16674","url":null,"abstract":"<p>Ultrasound-guided peripheral nerve, spinal and epidural anaesthesia deliver site-specific analgesia that lowers opioid use and the incidence of chronic postsurgical pain. Portable high-resolution ultrasound, introduced in the mid-2000s, enables direct needle visualisation and broadened safe block options.</p><p>Regional anaesthesia research publications have risen approximately 20-fold since the 1980s, with the steepest growth occurring after 2016 [<span>1</span>]. Randomised controlled trials, however, are often discontinued prematurely or remain unpublished. A 2022 meta-analysis of 326 protocols showed 30% stopped early and 21% were unpublished after 10 years, potentially wasting resources and slowing progress [<span>2</span>]. Anaesthesia mirrors this pattern; of 1052 abstracts presented at American Society of Anesthesiologists meetings (2001–2004), only 54% became papers and ‘positive’ trials were 42% more likely to publish [<span>3</span>]. Fewer than one in six completed anaesthesia trials on ClinicalTrials.gov post results, and almost half of published trials contain major outcome or sample-size discrepancies [<span>4, 5</span>]. Selective reporting skews meta-analyses, slows uptake of new blocks and undermines participant altruism. Therefore, we analysed registered regional anaesthesia studies to quantify completion and publication rates and identify factors linked to early termination or non-publication. Illuminating where and why trials go missing may guide practices that protect participant trust and strengthen the regional anaesthesia evidence base.</p><p>We searched ClinicalTrials.gov for phase 3–4 randomised controlled trials of regional anaesthesia. The strategy combined Medical Subject Heading (MeSH) and free-text terms for peripheral nerve, neuraxial and ultrasound-guided blocks (online Supporting Information Appendix S1). Trials with primary completion before 10 March 2023 (thereby guaranteeing ≥ 24 months for potential publication) and status ‘Completed’; ‘Terminated’; ‘Suspended’; ‘Withdrawn’; or ‘Unknown’ were eligible. For each trial we examined the registry ‘Publications’ field. If no matching citation appeared, three reviewers (TH, EB, AT) searched MEDLINE (via PubMed), Embase and Google Scholar independently using the title and the ClinicalTrials.gov identifier (NCT number). Publication was confirmed when a full manuscript or abstract, retracted papers included, matched the protocol. If a publication was absent, we emailed the study contact, principal investigator, chair and co-ordinator (sequentially) listed on ClinicalTrials.gov (weekly for 3 weeks, template in online Supporting Information Appendix S2). No response after 6 weeks classified ‘Terminated’/‘Suspended’/‘Withdrawn’ trials as ‘discontinued’ and ‘Completed’/‘Unknown’ trials as ‘not published’. If contact details were unavailable, the same rules applied. Raw data, correspondence and analyses are posted on Open Science Framework [<span>6</span>].</p><p>The se","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"80 8","pages":"1004-1007"},"PeriodicalIF":7.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anae.16674","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resident Doctors Conference Abstracts","authors":"","doi":"10.1111/anae.16654","DOIUrl":"https://doi.org/10.1111/anae.16654","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"80 S3","pages":"9-101"},"PeriodicalIF":7.5,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"List of Abstracts","authors":"","doi":"10.1111/anae.16653","DOIUrl":"https://doi.org/10.1111/anae.16653","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"80 S3","pages":"3-8"},"PeriodicalIF":7.5,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analgesic efficacy of continuous erector spinae plane block vs. opioid‐based regimen for postoperative pain management following video‐assisted thoracoscopic lung resection: a prospective, randomised, open‐label, non‐inferiority trial","authors":"Junqiang Hu, Weichao Zhou, Xi Zheng, Anyu Zhang, Qiang Huang, Chunmei Zhang, Yonghua Yao, Dianyu Lu, Wei Wei","doi":"10.1111/anae.16651","DOIUrl":"https://doi.org/10.1111/anae.16651","url":null,"abstract":"SummaryIntroductionVideo‐assisted thoracoscopic lung resection causes significant postoperative pain. We hypothesised that continuous erector spinae plane block would provide non‐inferior analgesia compared with a conventional opioid‐based regimen for this procedure.MethodsPatients were allocated randomly to continuous erector spinae plane block (continuous infusion of 0.25% ropivacaine via perineural catheters (5 ml.h<jats:sup>‐1</jats:sup>) combined with programmed intermittent bolus (10 ml every 6 h for the initial 24 h)) or conventional opioid‐based regimen (continuous infusion of opioid (2 μg.kg<jats:sup>‐1</jats:sup> sufentanil and 16 mg ondansetron diluted to 100 ml with 0.9% normal saline) at 2 ml.h<jats:sup>‐1</jats:sup> for 48 h). The primary outcome was overall analgesic efficacy with cough, quantified by the cumulative area under curve for the pain numeric rating scale scores, from post‐anaesthesia care unit discharge to 48 h postoperatively.ResultsThe cumulative area under curve for the pain numeric rating scale score in patients allocated to the continuous erector spinae plane block group was non‐inferior to those allocated to the conventional group (mean difference − 0.99, 95%CI ‐11.97–9.98, p = 0.011). Patients allocated to the continuous erector spinae plane block group showed superior quality of recovery‐15 scores at 24 h (median difference 11, 95%CI 6–16, p &lt; 0.001) and 48 h postoperatively (median difference 10, 95%CI 7–15, p &lt; 0.001), alongside reduced postoperative pulmonary complications (relative risk 0.45, 95%CI 0.21–0.96, p = 0.031). Safety outcomes favoured continuous erector spinae plane block, with lower incidences of postoperative nausea (relative risk 0.17, 95%CI 0.04–0.73, p = 0.005); retching (relative risk 0.11, 95%CI 0.02–0.89, p = 0.023); and dizziness (relative risk 0.22, 95%CI 0.07–0.72, p = 0.005).DiscussionFollowing video‐assisted thoracoscopic lung resection, continuous erector spinae plane block provides non‐inferior postoperative analgesia compared with conventional opioid‐based regimen whilst enhancing recovery quality significantly and reducing complications.","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"15 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}