Anaesthesia最新文献

{"title":"Effect of peri‐operative pharmacological interventions on postoperative delirium in patients having cardiac surgery: a systematic review and Bayesian network meta‐analysis","authors":"Ivo Queiroz, Lucas M. Barbosa, Mariano Gallo Ruelas, Beatriz Araújo, Maria L. R. Defante, Arthur H. Tavares, Cynthia Florencio de Mesquita, Tulio Pimentel, Beatriz Ximenes Mendes, Iuri Ferreira Felix, André Rivera, Rafael Oliva Morgado Ferreira, Helen M. de Oliveira, Bruno B. Righetto, Nathan J. Smischney, Guangyu Tong, Daqing Ma","doi":"10.1111/anae.16757","DOIUrl":"https://doi.org/10.1111/anae.16757","url":null,"abstract":"SummaryIntroductionPostoperative delirium is a common complication following cardiac surgery. Despite its known impact on patient outcomes, effective preventative strategies remain elusive. We aimed to perform a comprehensive Bayesian network meta‐analysis of randomised controlled trials assessing the effect of pharmacological interventions on the incidence of postoperative delirium.MethodsDatabases were searched from inception to September 2024. Our search was updated in January 2025. Eligible studies included randomised controlled trials reporting the incidence of postoperative delirium in patients having cardiac surgery treated with pharmacological interventions. Bayesian models were used to estimate risk ratios (RR) and mean differences with 95%CrI through Markov chain Monte Carlo. Interventions were ranked using the surface under the cumulative ranking curve. Sensitivity analyses and grading of recommendations, assessment, development and evaluation assessment were conducted to evaluate the robustness and certainty of evidence.ResultsSeventy‐nine randomised controlled trials comprising 24,827 patients were included, with 29 pharmacological interventions compared. Dexmedetomidine combined with melatonin was the most effective intervention, reducing the incidence of postoperative delirium compared with placebo (risk ratio 0.31, 95%CrI 0.13–0.69; low certainty). Dexmedetomidine with melatonin also significantly decreased intensive care unit stay (2.4 days, 95%CrI ‐3.50–1.10) and hospital stay (1.32 days, 95%CrI ‐2.09 to ‐0.57). Other interventions, including ketamine and risperidone, showed potential efficacy but with low or very low certainty of evidence.DiscussionWe identified dexmedetomidine with melatonin as the most effective pharmacological strategy for preventing postoperative delirium following cardiac surgery. Whilst these findings highlight potential benefits, the low certainty of evidence underscores the need for more high‐quality primary evidence.","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"6 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144923861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of anaesthesia and surgery on sleep–wake timing and subjective sleep quality in children: an observational study","authors":"Arjen J. G. Meewisse, Sharon J. Meijer, Kee Fong Choi, Stefan Kanters, Kim B. Meekel, Pia Burger, Reinoud J. B. J. Gemke, Dirk Jan Stenvers, Jeroen Hermanides, Mark L. van Zuylen, Jorinde Polderman","doi":"10.1111/anae.16710","DOIUrl":"https://doi.org/10.1111/anae.16710","url":null,"abstract":"SummaryIntroductionSurgery and anaesthesia can cause disruption of the circadian timing system and diurnal sleep–wake rhythm. However, it remains unknown how sleep–wake rhythm in children is affected by anaesthesia and surgery, and if anaesthesia without a surgical procedure disturbs sleep–wake cycles.MethodsWe recruited children aged 1–11 y undergoing anaesthesia for an elective surgical procedure or magnetic resonance imaging. The Children's Chronotype Questionnaire, Children's Sleep Habits Questionnaire and a daily sleep diary from three days before until seven days after anaesthesia were used to assess sleep–wake rhythm and sleep quality.ResultsIn total, 117 patients (median (IQR [range]) age 4 (2–6 [1–11]) y, 56 (47.9%) female) were included. The midpoint of sleep did not change on the night after anaesthesia when compared with three nights before (estimated median time difference 8 min, 95%CI ‐15–1, p = 0.12, n = 114). Median (IQR [range]) midpoint of sleep at baseline was 01.42 (01.22–02.19 [00.10–03.15]) for the surgical group and 01.22 (01.03–02.07 [00.15–04.02]) for the magnetic resonance imaging group. The midpoint of sleep did not shift on the night after anaesthesia for either group (surgical group: 01.37 (01.07–02.15 [23.00–03.12]), estimated median time difference ‐15 min, 95%CI ‐27–0, p = 0.07, n = 58; magnetic resonance imaging group: 01.30 (01.07–02.07 [23.45–05.00]), estimated median time difference 0 min, 95%CI ‐9–9, p = 0.90, n = 56), and there was no between‐group difference (estimated median time difference: ‐15 min, 95%CI ‐30–0 min, p = 0.07). Subjective sleep quality was unaffected.DiscussionWe found no disruption of sleep–wake rhythm in children after anaesthesia and surgery. Further research is needed to see whether more invasive procedures and accompanying anaesthesia pose a risk of disrupting sleep–wake rhythms in children.","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"10 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144915550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravenous methadone for pain management in cardiac surgery: a randomised controlled trial with plasma concentration analysis*","authors":"Henry Man Kin Wong, Veronica Ka Wai Lai, Sandra Lok Ching Chiu, Wai Tat Wong, Siu Kwan Wo, Joan Zhong Zuo, Xiaodong Liu, Randolph Hung Leung Wong, Kwok Ming Ho","doi":"10.1111/anae.16754","DOIUrl":"https://doi.org/10.1111/anae.16754","url":null,"abstract":"SummaryIntroductionPostoperative pain after cardiac surgery remains significant despite the administration of opioids. Methadone may improve pain control and decrease the need for postoperative opioids. Randomised controlled trials, however, are limited and the effects of cardiopulmonary bypass on methadone pharmacokinetics are unclear. The aims of this study were to compare methadone and morphine in cardiac surgery, measuring methadone concentrations and correlating them with pain control.MethodsPatients undergoing cardiac surgery that required cardiopulmonary bypass were allocated randomly to receive either 0.2 mg.kg<jats:sup>‐1</jats:sup> methadone or 0.2 mg.kg<jats:sup>‐1</jats:sup> morphine (based on actual body weight, maximum 20 mg for both drugs). Postoperative pain was assessed at 15 min and 8 h, 12 h, 24 h, 48 h and 72 h after tracheal extubation, by analysis of morphine consumption and pain scores. Opioid‐related adverse events were evaluated. Postoperative blood samples were collected for 96 h to measure plasma methadone concentrations.ResultsIn total, 80 patients were analysed (40 allocated to the methadone group, 40 allocated to the morphine group). Patients allocated to the methadone group had significantly reduced 24‐h and total postoperative morphine requirements compared to those allocated to the morphine group (median (IQR [range]) 9 (5–16 [0–40]) mg vs. 24 (17–43 [4–54]) mg (p &lt; 0.001) at 24 h and 35 (23–52 [5–66]) mg vs. 11 (7–20 [0–44]) mg (p &lt; 0.001) total). Patients allocated to the methadone group had lower pain scores at rest (β ‐2.24, standard error 0.49, p &lt; 0.001) and on coughing (β ‐2.16, standard error 0.50, p &lt; 0.001). There was no difference in the incidence of opioid‐related adverse effects between the two groups. Plasma methadone concentration decreased during cardiopulmonary bypass but remained above the minimum effective analgesic concentration for approximately 24 h after administration (mean (SD) 51 (24.7) ng.ml<jats:sup>‐1</jats:sup> at baseline to 30 (10.7) ng.ml<jats:sup>‐1</jats:sup> at 24 h).DiscussionIntra‐operative methadone reduces postoperative analgesia requirements without increasing the incidence of opioid‐related adverse events.","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"18 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144910953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between persistent postoperative anaemia and mortality 1 year after valvular heart surgery: a retrospective cohort study*","authors":"Hee Won Choi, Hyun‐Soo Zhang, Jae‐Kwang Shim, Jin Sun Cho, Seo Hee Ko, Young Lan Kwak","doi":"10.1111/anae.16753","DOIUrl":"https://doi.org/10.1111/anae.16753","url":null,"abstract":"SummaryIntroductionPeri‐operative anaemia is a common problem in patients undergoing cardiac surgery. Postoperative anaemia is not well understood relative to pre‐operative anaemia; limited data exist on haemoglobin recovery and mortality after discharge, especially in the era of restrictive transfusion practice. We aimed to investigate the associations of pre‐operative and persistent postoperative anaemia with 1‐year mortality in patients undergoing valvular heart surgery.MethodsWe identified patients who had undergone valvular heart surgery and allocated them to one of four groups based on their pre‐operative (haemoglobin ≥ 130 g.l<jats:sup>‐1</jats:sup> and &lt; 130 g.l<jats:sup>‐1</jats:sup> in men and ≥ 120 g.l<jats:sup>‐1</jats:sup> and &lt; 120 g.l<jats:sup>‐1</jats:sup> in women) and postoperative (measured 2 months after surgery; haemoglobin ≥ 100 g.l<jats:sup>‐1</jats:sup> and &lt; 100 g.l<jats:sup>‐1</jats:sup> in both men and women) anaemia status. The four groups were: pre‐ and postoperative non‐anaemia (non‐anaemia–non‐anaemia); pre‐operative anaemia–postoperative non‐anaemia (anaemia–non‐anaemia); pre‐ and postoperative anaemia (anaemia–anaemia); and pre‐operative non‐anaemia–postoperative anaemia (non‐anaemia–anaemia). The primary outcome was 1‐year mortality.ResultsData from 2486 patients were included. Pre‐operative anaemia was diagnosed in 1107 patients (44.5%) and 279 (11.9%) met the diagnostic criteria for persistent anaemia 2 months postoperatively. The overall 1‐year mortality rate was 3.3%. The highest rate was observed in the anaemia–anaemia group (17.8%), followed by the non‐anaemia–anaemia (13.1%), anaemia–non‐anaemia (2.9%) and non‐anaemia–non‐anaemia (0.5%) groups. Multivariable Cox regression analysis showed that the non‐anaemia–anaemia group had the highest risk of 1‐year mortality (adjusted hazard ratio 14.44, 95%CI 4.88–42.69), followed by the anaemia–anaemia group (adjusted hazard ratio 10.94, 95%CI 4.41–27.16).DiscussionOur study highlights the high prevalence of persistent anaemia following valvular heart surgery. Persistent anaemia 2 months postoperatively is associated with an increased risk of 1‐year mortality.","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"34 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144910955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Too unfit not to have surgery: is non‐operative care for hip fracture patients a viable option?","authors":"Nicolai B. Foss, Søren Overgaard","doi":"10.1111/anae.16735","DOIUrl":"https://doi.org/10.1111/anae.16735","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"17 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology, patient outcome and complications after non‐operative management of hip fracture: a systematic review","authors":"James Winfield, Lynn McNicoll, Iain K. Moppett","doi":"10.1111/anae.16732","DOIUrl":"https://doi.org/10.1111/anae.16732","url":null,"abstract":"SummaryIntroductionSurgery is the preferred treatment for hip fracture in older people. However, a proportion of patients with hip fracture do not receive surgery. There is a lack of contemporary evidence describing this patient population and what their associated outcomes are. We aimed to describe the variation in non‐operative management and its outcomes around the world.MethodsWe performed a systematic review and meta‐analysis of older people presenting to hospital with hip fracture, comparing those with and without surgery for non‐operative proportions, mortality and other outcomes. Risk of bias was assessed using the Newcastle‐Ottawa Scale. We performed a random effects meta‐analysis with adjustment for clustering.ResultsOf 4437 screened studies, 185 were included from 172 separate cohorts, 44 countries, six continents and involving 10,763,994 patients. The overall proportion of non‐operative management was 8.4% (95%CI 7.2–9.7%) with wide within‐country and regional variation. There was no consistent association of non‐operative management proportions with the admission characteristics of sex, fracture type or patient ethnicity. Non‐operative management was associated with a greater relative risk of death at all time points. Risk of bias was generally low except for the expected confounding by indication.DiscussionNon‐operative management of hip fracture is relatively common, but there is wide variation that is unexplained by differences in patient characteristics. The evidence is limited by incomplete reporting of patient characteristics and outcomes, and a lack of controlled studies even in the highest risk populations. Further work is needed to understand this decision‐making process.","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"12 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of default videolaryngoscopy instead of direct laryngoscopy for tracheal intubation: a narrative review of evidence and experiences","authors":"Fiona E. Kelly, Anette Scholz, Jonathan Mayer, Peter Groom, Barry McGuire, Tim M. Cook","doi":"10.1111/anae.16731","DOIUrl":"https://doi.org/10.1111/anae.16731","url":null,"abstract":"SummaryIntroductionDefault videolaryngoscopy – use of a videolaryngoscope in preference to a direct laryngoscope – remains a hotly debated topic. High‐risk tracheal intubations performed during the COVID‐19 pandemic added to the extensive existing evidence of advantages of videolaryngoscopy for patients and staff. Despite this, and calls for implementation of default videolaryngoscopy, it has not been adopted widely.MethodsWe summarise current evidence for the benefits of videolaryngoscopy and discuss (and where appropriate dispute) the common reasons given for not using videolaryngoscopy. The experiences of five UK NHS hospitals which have made a move to default videolaryngoscopy are described, with practical advice to assist other hospitals planning similar projects.ResultsSeveral recent large randomised controlled trials and meta‐analyses, incorporating data from over 200 trials, support the use of videolaryngoscopes. Guidelines and reports published since 2015 have recommended immediate access to videolaryngoscopes plus training and skill acquisition in the required techniques. Recent guidelines have recommended the routine use of videolaryngoscopes whenever possible. Reported advantages include: technical benefits (improved safety, efficacy and ease of tracheal intubation plus fewer complications); non‐technical benefits (including improved teamwork and communication); improved direct laryngoscopy training; and environmental benefits. Reasons cited for not using a videolaryngoscope include concerns that they: are unnecessary; lead to decay in or failure to learn direct laryngoscopy skills; videolaryngoscopy failure; ineffectiveness in a soiled airway; cost; and challenges relating to decontamination of reusable blades. We discuss these and, where appropriate, provide counter arguments.DiscussionThis narrative review provides the relevant evidence and information for clinicians, managers, procurement teams and sterile services departments to use, should a business case be proposed to implement default videolaryngoscopy. We describe effective practical strategies for addressing implementation challenges.","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"26 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study outcome measurements: statistically insignificant or non-inferior? A reply","authors":"Byung-Moon Choi,&nbsp;the authors","doi":"10.1111/anae.16745","DOIUrl":"10.1111/anae.16745","url":null,"abstract":"<p>We thank Professor Sethuraman for his comments [<span>1</span>] on our article [<span>2</span>]. Regarding the concern that the assumption of non-inferiority lacked justification, we believe it is important to consider the evidence available at the time the study was designed, rather than applying current standards retrospectively. Our trial was registered in December 2021, at which time there were no published studies directly comparing the incidence of delirium between remimazolam and propofol. Furthermore, since there had been reports suggesting that benzodiazepines could increase the risk of delirium in patients who are critically ill [<span>3, 4</span>], adopting a non-inferiority design was a reasonable choice at the time. When the study was completed and the article was written, several relevant studies had been published, and we considered it appropriate to reflect their findings in the introduction [<span>5</span>].</p><p>The second point concerns whether our study adhered to the principles of non-inferiority trial design and reporting. We believe this may reflect a misunderstanding. The study was, in fact, conducted within a non-inferiority framework. The absence of an explicit statement of non-inferiority in the Clinical Research Information Service registry reflects a limitation of the platform itself, which classifies studies only as interventional or observational and does not include an item to indicate non-inferiority designs. At the time of planning, no previous trials had compared remimazolam and propofol directly in this specific context. Consequently, sample size estimation had to rely on pilot data. Figure 1 supports our conclusion of non-inferiority.</p><p>The third point relates to the clinical interpretation of the non-inferiority design, specifically the omission of pharmaco-economic considerations. We acknowledge that this aspect was not addressed. However, we believe that while cost is an important factor, it is not a required component in the interpretation of every non-inferiority trial. As mentioned in the introduction, remimazolam offers several clinical advantages over propofol, including no injection pain, greater haemodynamic stability, and more rapid recovery [<span>2</span>]. For clinicians who place greater value on these features, the higher cost of remimazolam may be acceptable. We believe that our findings may serve as a meaningful reference when selecting anaesthetic drugs for older patients.</p><p>Non-inferiority trials are generally more complex and methodologically demanding than conventional randomised trials, but they are feasible within clinical research. Our study adhered to the principles of non-inferiority trial design, and we consider the interpretation of the results to be appropriate in showing non-inferiority.</p>","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"80 10","pages":"1284-1285"},"PeriodicalIF":6.9,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/epdf/10.1111/anae.16745","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Individual and combined effects of chemical and mechanical power on postoperative pulmonary complications: a secondary analysis of the REPEAT study.","authors":"Lukas M Müller-Wirtz, Thijs A Lilien, William M Patterson, Sascha Ott, Roland C E Francis, Marcelo Gama de Abreu, Ary Serpa Neto, Reinout A Bem, David M P van Meenen, Marcus J Schultz","doi":"10.1111/anae.16725","DOIUrl":"10.1111/anae.16725","url":null,"abstract":"<p><strong>Introduction: </strong>Intra-operative supplemental oxygen and mechanical ventilation expose the lungs to potentially injurious energy. This can be quantified as 'chemical power' and 'mechanical power', respectively. In this study, we sought to determine if intra-operative chemical and mechanical power, individually and/or in combination, are associated with postoperative pulmonary complications.</p><p><strong>Methods: </strong>Using an individual patient data analysis of three randomised clinical trials of intra-operative ventilation, we summarised intra-operative chemical and mechanical power using time-weighted averages. We evaluated the association between intra-operative chemical and mechanical power and a collapsed composite of postoperative pulmonary complications using multivariable logistic regression to estimate the odds ratios related to the effect of 1 J.min^-1 increase in chemical or mechanical power with adjustment for demographic and intra-operative characteristics. We also included an interaction term to assess for potential synergistic effects of chemical and mechanical power on postoperative pulmonary complications.</p><p><strong>Results: </strong>Of 3837 patients recruited to three individual trials, 2492 with full datasets were included in the analysis. Intra-operative time-weighted average (SD) chemical power was 10.2 (3.9) J.min^-1 and mechanical power was 10.5 (4.4) J.min^-1. An increase of 1 J.min^-1 in chemical power was associated with 8% higher odds of postoperative pulmonary complications (OR 1.08, 95%CI 1.05-1.10, p < 0.001), while the same increase in mechanical power raised odds by 5% (OR 1.05, 95%CI 1.02-1.08, p = 0.003). We did not find evidence of a significant interaction between chemical and mechanical power (p = 0.40), suggestive of an additive rather than synergistic effect on postoperative pulmonary complications.</p><p><strong>Discussion: </strong>Both chemical and mechanical power are independently associated with postoperative pulmonary complications. Further work is required to determine causality.</p>","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":" ","pages":""},"PeriodicalIF":6.9,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic postsurgical pain after caesarean delivery: should we care about pain incidence and intensity or pain interference?","authors":"Ruth Landau, Pervez Sultan","doi":"10.1111/anae.16750","DOIUrl":"10.1111/anae.16750","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":" ","pages":""},"PeriodicalIF":6.9,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}