Aesthetic Surgery Journal最新文献

{"title":"Local Tranexamic Acid vs Placebo in Patients Undergoing Septorhinoplasty: A Systematic Review and Meta-analysis of Randomized Controlled Trials.","authors":"Lorenzo Di Martino, Jonathan Mokhtar, Fatemeh Akbarpoor, Lucas Kreutz-Rodrigues, Krishna Vyas, Curtis L Cetrulo, Alexandre G Lellouch","doi":"10.1093/asj/sjaf172","DOIUrl":"https://doi.org/10.1093/asj/sjaf172","url":null,"abstract":"<p><p>Systemic tranexamic acid (TXA) reduces bleeding in nasal surgery but carries theoretical systemic risks. Topical TXA is an alternative, yet its efficacy in rhinoplasty and septoplasty is controversial because of inconsistent findings in individual trials. The aim of the authors of this systematic review and meta-analysis is to synthesize the evidence on the effectiveness of topical TXA in this setting. A systematic literature search was conducted from inception to July 2025 for randomized controlled trials (RCTs) comparing topical TXA to control in adults undergoing rhinoplasty, septoplasty, or septorhinoplasty. Primary outcomes included intraoperative blood loss, postoperative edema, and ecchymosis. Data were pooled using a random-effects model. Seven RCTs comprising 514 patients were included. The use of topical TXA was associated with a significant reduction in intraoperative blood loss (standardized mean difference [SMD] -1.20, 95% CI, -2.34 to -0.07; P = .04), overall postoperative edema (SMD -0.87, 95% CI, -1.35 to -0.39; P < .001), and ecchymosis (SMD -1.16, 95% CI, -1.63 to -0.69; P < .001). Secondary outcomes, such as surgeon satisfaction (SMD 0.74, 95% CI, -0.24 to 1.73, P  = .14) and operative time (SMD -1.03, 95% CI, -2.69 to 0.62, P  = .22), showed no statistically significant differences between the groups. In patients undergoing rhinoplasty or septoplasty, topical TXA significantly reduces intraoperative blood loss and postoperative edema and ecchymosis. These findings suggest it may serve as an effective adjunct for improving hemostasis and postoperative recovery. Level of Evidence: 3 (Therapeutic).</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145090746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Efficacy of Stromal Vascular Fraction and Adipose-derived Stem Cells in UVB-induced Skin Damage in Nude Mice.","authors":"Hui-Yi Hsiao, Chao-Yi Lai, Yung-Chun Chang, Shih-Han Huang, Jung-Ju Huang","doi":"10.1093/asj/sjaf179","DOIUrl":"https://doi.org/10.1093/asj/sjaf179","url":null,"abstract":"<p><strong>Background: </strong>Chronic UVB exposure accelerates skin aging by inducing oxidative stress and inflammation, leading to dehydration, reduced collagen density, and impaired epidermal and dermal integrity. Stem cell-based therapies, including the use of the stromal vascular fraction (SVF) and adipose-derived stem cells (ASCs), have emerged as promising approaches for skin regeneration.</p><p><strong>Objectives: </strong>This study evaluated the therapeutic effects of SVF and ASCs on UVB-induced skin damage.</p><p><strong>Methods: </strong>The mice were exposed to UVB irradiation (290-310 nm) for eight weeks to establish a photoaging model. Following UVB exposure, the SVF or ASCs were injected into the dorsal skin, and the skin samples were analyzed.</p><p><strong>Results: </strong>UVB exposure significantly reduced skin hydration (-26%), decreased collagen density, and led to a decrease in the thickness of the epidermal and dermal layers. The SVF and ASC treatments improved skin hydration, enhanced extracellular matrix remodeling, and increased collagen density. Both treatments reduced oxidative stress by decreasing reactive oxygen species (ROS) levels, with SVF-treated samples exhibiting increased BMAL1 expression. SVF and ASCs also promoted angiogenesis and lymphangiogenesis. A reduction in macrophage infiltration and a shift in polarization from the proinflammatory M1 phenotype to the anti-inflammatory M2 phenotype were also observed in the SVF and ASC groups, with ASCs exhibiting stronger immunomodulatory effects. The SVF and ASCs each displayed distinct therapeutic advantages in skin tissue restoration.</p><p><strong>Conclusions: </strong>These findings highlight the potential of the SVF and ASCs as therapeutic strategies for UVB-induced skin aging, warranting further clinical investigation.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145090747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scalpel Versus Electrocautery for Upper Lateral Cartilage Contouring in Dorsal Preservation Rhinoplasty: A Retrospective Comparative Study.","authors":"Serhat Şibar, Ayhan Işık Erdal, Mustafa Talha Okutan","doi":"10.1093/asj/sjaf180","DOIUrl":"https://doi.org/10.1093/asj/sjaf180","url":null,"abstract":"<p><strong>Background: </strong>Dorsal preservation rhinoplasty maintains dorsum integrity while refining nasal aesthetics, but dorsal hump recurrence is a common limitation, especially after extensive reshaping. Electrocautery offers precise cartilage contouring, yet its role in dorsal preservation rhinoplasty is under-investigated.</p><p><strong>Objectives: </strong>To compare the outcomes of scalpel-based mechanical reshaping versus electrocautery-assisted thermal reshaping of the upper lateral cartilage shoulders in low septal strip dorsal preservation rhinoplasty.</p><p><strong>Methods: </strong>This retrospective study included 205 patients who underwent low septal strip dorsal preservation rhinoplasty via open approach between February 2021 and May 2023. Patients were grouped according to the method used for reshaping the upper lateral cartilage: Group I underwent mechanical reshaping with a scalpel (mechanical/scalpel group), and Group II underwent thermal reshaping using monopolar electrocautery (thermal/electrocautery group). Dorsal hump recurrence and patient-reported outcomes were evaluated using standardized 12-month postoperative photographs and the Rhinoplasty Outcome Evaluation (ROE) questionnaire, respectively.</p><p><strong>Results: </strong>A total of 88 patients were included in the scalpel group and 117 in the electrocautery group. Demographic data, hump morphology, and amount of hump reduction were similar between groups. However, the recurrence rate of the dorsal hump was significantly lower in the electrocautery group (2.5%) compared to the scalpel group (13.6%). ROE scores were high in both groups (84.4 vs. 85.0, p>0.05).</p><p><strong>Conclusions: </strong>Electrocautery-assisted upper lateral cartilage reshaping in dorsal preservation rhinoplasty offers more consistent contouring and reduced recurrence rates compared to scalpel-based technique. It represents a valuable technical adjunct, especially in cases with challenging dorsal anatomy.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145090735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Degradability of Hyaluronic Acid by Ovine and Recombinant Human Hyaluronidase.","authors":"Tyler Safran, Roy Khalaf, Andrei Metelitsa, Julie Woodward, Andreas Nikolis","doi":"10.1093/asj/sjaf127","DOIUrl":"10.1093/asj/sjaf127","url":null,"abstract":"<p><strong>Background: </strong>The mainstay of treatment for adverse events to hyaluronic acid filler is the use of hyaluronidase (HYAL); however, the dose and dilution are not standardized.</p><p><strong>Objectives: </strong>The objective of this study was to examine differential dilutions and concentrations of HYAL, and to compare the effectiveness of ovine and human HYAL.</p><p><strong>Methods: </strong>Fillers were selected for study based on a variety of rheologic factors. A 0.2-mL dose of product was selected for use based on previous studies. Degradation was assessed by comparing both ovine and recombinant HYAL over a range of concentrations and dilutions.</p><p><strong>Results: </strong>In the 2:1 dilution group, Restylane Lidocaine (Galderma, Lausanne, Switzerland) was degraded by 100 U of ovine HYAL after 50 minutes. No other filler was completely degraded; Restylane Lyft (Galderma) was partially degraded after 1 hour of treatment with 100 U of HYAL. In both the 3:1 and 4:1 dilution groups, Restylane Shaype (Galderma) and Restylane Lyft fillers were most susceptible to degradation, dissolving within 30 minutes with 100 U of recombinant HYAL and within 40 minutes with 100 U of ovine HYAL. Juvéderm and RHA4 fillers were the most resistant, requiring 300 U of HYAL for degradation within 1 hour. Beyond a 3:1 dilution ratio, no further improvement was observed.</p><p><strong>Conclusions: </strong>This study demonstrates that 300 U of hyaluronidase is sufficient to degrade 0.2 mL of the most resistant hyaluronic acid fillers within 1 hour. Importantly, a minimum dilution of 3:1 should be used to provide adequate fluid for dissolving filler. Ovine HYAL appears to be just as effective as recombinant HYAL in terms of dissolving product.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"1086-1093"},"PeriodicalIF":3.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of an Artificial Intelligence-Driven Classification of Tuberous Breast Deformity: A Siamese Network Approach With a Continuous Tuberosity Score.","authors":"Stefano Vaccari, Alberto Paderno, Simone Furlan, Mattia Federico Cavallero, Alessandro Marco Lupacchini, Riccardo Di Giuli, Marco Klinger, Francesco Klinger, Valeriano Vinci","doi":"10.1093/asj/sjaf090","DOIUrl":"10.1093/asj/sjaf090","url":null,"abstract":"<p><strong>Background: </strong>Tuberous breast deformity (TBD) is a congenital condition characterized by constriction of the breast base, parenchymal hypoplasia, and areolar herniation. The absence of a universally accepted classification system complicates diagnosis and surgical planning, leading to variability in clinical outcomes. Artificial intelligence (AI) has emerged as a powerful adjunct in medical imaging, enabling objective, reproducible, and data-driven diagnostic assessments.</p><p><strong>Objectives: </strong>This study introduces an AI-driven diagnostic tool for TBD classification using a Siamese network trained on paired frontal and lateral images. Additionally, the model generates a continuous Tuberosity Score (ranging from 0 to 1) based on embedding vector distances, offering an objective measure to enhance surgical planning and improved clinical outcomes.</p><p><strong>Methods: </strong>A dataset of 200 expertly classified frontal and lateral breast images (100 tuberous, 100 non-tuberous) was used to train a Siamese network with contrastive loss. The model extracted high-dimensional feature embeddings to differentiate tuberous from non-tuberous breasts. Five-fold cross-validation ensured robust performance evaluation. Performance metrics included accuracy, precision, recall, and F1-score. Visualization techniques, such as t-distributed Stochastic Neighbor Embedding clustering and occlusion sensitivity mapping, were employed to interpret model decisions.</p><p><strong>Results: </strong>The model achieved an average accuracy of 96.2% ± 5.5%, with balanced precision and recall. The Tuberosity Score, derived from the Euclidean distance between embeddings, provided a continuous measure of deformity severity, correlating well with clinical assessments.</p><p><strong>Conclusions: </strong>This AI-based framework offers an objective, high-accuracy classification system for TBD. The Tuberosity Score enhances diagnostic precision, potentially aiding in surgical planning and improving patient outcomes.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"1094-1100"},"PeriodicalIF":3.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on: Evaluation of Major Complications Following Ruptured Implant Removal: A National Surgery Quality Improvement Program Database Analysis.","authors":"William P Adams","doi":"10.1093/asj/sjaf146","DOIUrl":"10.1093/asj/sjaf146","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"NP193"},"PeriodicalIF":3.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144740952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Major Complications Following Ruptured Implant Removal: A National Surgery Quality Improvement Program Database Analysis.","authors":"Puja Jagasia, Jason Zhang, Isabel Cohen, John Y S Kim, Megan Fracol","doi":"10.1093/asj/sjaf068","DOIUrl":"10.1093/asj/sjaf068","url":null,"abstract":"<p><strong>Background: </strong>After the removal of ruptured breast implants, patients may elect to replace or not replace ruptured implants. They also may elect to undergo mastopexy alone without replacement of breast implants to maintain a more aesthetic shape of the breast after ruptured implant removal.</p><p><strong>Objectives: </strong>The objective of this study was to cultivate an understanding of demographic differences in patient populations who opted for various surgical options at the time of ruptured implant removal. We hypothesized that procedures performed at the time of ruptured breast implant removal had a favorable complication profile.</p><p><strong>Methods: </strong>Utilizing the American College of Surgeons' National Surgery Quality Improvement Program (NSQIP) database (2011-2022), surgeries performed at the same time of ruptured breast implant removal (CPT 19330) were analyzed. To capture cosmetic patients, any patient with an ICD or CPT code related to breast cancer was excluded. Patients with implant replacement were identified with appropriate CPT codes. For those who did not undergo implant replacement, a subgroup was created for those who underwent mastopexy. Demographics and complication rates between groups were compared with Welch's t tests or chi-square tests.</p><p><strong>Results: </strong>The majority (54.9%; 1662/3028) of patients elected to have new implants placed. Of those who did not undergo implant replacement, 12.2% (167/1366) had a mastopexy. Regardless of whether the patient chose to replace implants or undergo mastopexy, there were low complication rates, including infection (0.9%-2.4%), abscess (0.0%-1.4%), dehiscence (0.3%-0.5%), and bleeding (0.0%-0.6%). Rates of reoperation (1.2%-1.8%) and readmission (0.0%-1.8%) also were low.</p><p><strong>Conclusions: </strong>Removal of ruptured implants is a safe procedure, with low levels of complication, regardless of whether the patient chooses to replace or not to replace ruptured implants.</p><p><strong>Level of evidence: 4 (therapeutic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"NP187-NP192"},"PeriodicalIF":3.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144740953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinically Relevant Manual One-Shot Learning Technique (MOST) to Personalize Fractional Carbon Dioxide Laser Treatment for Eyelid Scars.","authors":"Dingqiao Wang, Zhen Mao, Wuyou Gao, Yanjing Huang, Xingyi Li, Jun Mao, Rongxin Chen, Xuanwei Liang, Xianchai Lin","doi":"10.1093/asj/sjaf091","DOIUrl":"10.1093/asj/sjaf091","url":null,"abstract":"<p><strong>Background: </strong>Hypertrophic and keloid eyelid scars cause functional and aesthetic problems. Traditional fractional carbon dioxide (CO2) laser treatments require multiple sessions and use uniform parameters regardless of scar characteristics, limiting their effectiveness for complex eyelid scars.</p><p><strong>Objectives: </strong>In this study, the authors evaluate the efficacy and safety of the Manual One-shot Learning Technique (MOST) with fractional CO2 laser for personalized treatment of eyelid scars.</p><p><strong>Methods: </strong>A retrospective study involved 154 patients with hypertrophic and keloid eyelid scars treated with the MOST fractional CO2 laser. Functional and aesthetic outcomes were assessed utilizing degree of incomplete eyelid closure, ectropion, and Vancouver Scar Scale (VSS). Patients were followed up for a total of 12 months to evaluate outcomes and monitor complications.</p><p><strong>Results: </strong>The study included 154 patients (98 males, 56 females; mean age 32.6 ± 14.2 years). A single treatment session resulted in significant improvements, with a mean VSS score reduction of 2.75 ± 1.50 (P = .021), and 57.8% of patients achieving >75% scar clearance. After 1 to 3 treatment sessions, all patients showed significant functional and aesthetic improvements, with incomplete eyelid closure and ectropion significantly reduced (both P < .001), VSS scores decreased by 3.02 ± 1.76 (P < .001), and 90.9% of patients achieved >75% scar clearance. Complications included recurrence (10.4%), hypopigmentation (5.2%), and skin atrophy (5.2%).</p><p><strong>Conclusions: </strong>The MOST laser technique significantly improves functional and aesthetic outcomes for eyelid scars with fewer treatment sessions. By personalizing treatment based on tissue response, this approach enhances efficiency while reducing both patient burden and resource use.</p><p><strong>Level of evidence: 4 (therapeutic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"1002-1011"},"PeriodicalIF":3.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Deep Plane Facelift: A Classified Approach.","authors":"Mirza Firat","doi":"10.1093/asj/sjaf110","DOIUrl":"10.1093/asj/sjaf110","url":null,"abstract":"<p><strong>Background: </strong>Traditional facelift techniques, although effective in addressing facial aging, are often associated with visible scarring and stigmas. These factors contribute to patient hesitation and a growing preference for nonsurgical alternatives. In recent years, endoscopic approaches have gained popularity by offering scar-concealed access and deep plane dissection, but many techniques lack a standardized framework for patient selection and reproducibility.</p><p><strong>Objectives: </strong>The aim of this study was to present a systematic endoscopic facelift technique which proposes a 5-group classification system to guide patient-specific surgical planning and optimize aesthetic outcomes.</p><p><strong>Methods: </strong>A total of 393 patients underwent endoscopic facelift surgery performed by a single surgeon between 2020 and 2024. Patients were categorized into 5 groups based on facial aging patterns and anatomical needs, including brow lift, midface lift, lower facelift, and neck correction. The technique emphasized minimal skin undermining, vertical vector elevation, and cable suture suspension. All patients were followed for a minimum of 12 months postoperatively. Complications, revisions, and outcomes were recorded prospectively.</p><p><strong>Results: </strong>There were no cases of permanent nerve injury. Revision surgery for cosmetic concerns was performed in 19 patients (4.8%), most of whom were among the first 100 cases.</p><p><strong>Conclusions: </strong>This vertical vector endoscopic facelift technique demonstrates consistent aesthetic results with low complication and revision rates. By combining a classification-based surgical strategy with minimally invasive access and deep anatomical correction, this method offers a reproducible, safe, and natural-appearing alternative to traditional facelift approaches. Future studies will aim to incorporate objective assessments and patient- reported outcome measures.</p><p><strong>Level of evidence: 4: </strong>(Therapeutic).</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"989-1001"},"PeriodicalIF":3.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Labiaplasty on Self-perception and Quality of Sexual Life in Women: Functional and Psychological Reflections.","authors":"Elif Ucar, Melih Bestel","doi":"10.1093/asj/sjaf145","DOIUrl":"10.1093/asj/sjaf145","url":null,"abstract":"<p><strong>Background: </strong>Female genital cosmetic procedures, particularly labiaplasty, have become increasingly popular due to rising concerns about both aesthetic dissatisfaction and functional limitations. Enlarged or asymmetric labia may result in physical discomfort, hygiene-related problems, or reduced sexual satisfaction. Although labiaplasty is believed to improve genital self-image, emotional well-being, and sexual functioning, studies employing validated psychometric tools to assess these outcomes remain limited.</p><p><strong>Objectives: </strong>In this study we aimed to evaluate the psychological, functional, and sexual outcomes of labiaplasty in women, focusing on changes in genital self-perception, depression levels, sexual function, and overall quality of sexual life.</p><p><strong>Methods: </strong>A total of 48 women, ages between 21 and 52 years, who underwent labiaplasty were included in the study. Standardized instruments including the Beck Depression Inventory (BDI), Female Genital Self-Image Scale (FGSIS), Female Sexual Function Index (FSFI), Quality of Sexual Experience scale (QSE), and Sexual Quality of Life Questionnaire-Female (SQoL-F) were administered before and after surgery to assess multidimensional outcomes.</p><p><strong>Results: </strong>The leading reasons for seeking labiaplasty were labial asymmetry (47.9%), low self-esteem (41.7%), and negative partner experiences (10.4%). Postoperative scores revealed significant improvements in all assessed domains. BDI scores decreased significantly (P = .037), and FGSIS, FSFI, QSE, and SQoL-F scores increased markedly (P < .001 for each), reflecting enhanced genital self-image, sexual function, and quality of life.</p><p><strong>Conclusions: </strong>Labiaplasty appears to offer meaningful benefits beyond aesthetics, contributing to improved psychological well-being and sexual health. These findings support its value as a functional and psychosocially beneficial intervention in appropriately selected patients.</p><p><strong>Level of evidence: 4 (therapeutic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"NP194-NP199"},"PeriodicalIF":3.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}