Aesthetic Surgery Journal最新文献

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Critical Evaluation of Generative Text-to-Image AI Models in Plastic Surgery: Balancing Promise and Precision. 整形外科中生成文本到图像的人工智能模型的关键评价:平衡承诺和精度。
IF 3 2区 医学
Aesthetic Surgery Journal Pub Date : 2025-05-28 DOI: 10.1093/asj/sjaf098
Berk B Ozmen, Graham S Schwarz
{"title":"Critical Evaluation of Generative Text-to-Image AI Models in Plastic Surgery: Balancing Promise and Precision.","authors":"Berk B Ozmen, Graham S Schwarz","doi":"10.1093/asj/sjaf098","DOIUrl":"https://doi.org/10.1093/asj/sjaf098","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aesthetic Submandibular Gland Resection: A Review of Complication Incidence and Prevention. 美学颌下腺切除术:并发症发生率及预防综述。
IF 3 2区 医学
Aesthetic Surgery Journal Pub Date : 2025-05-27 DOI: 10.1093/asj/sjaf096
Sara B A Morel, Luis H Macias, Ritu Chopra, Joshua Vorstenbosch, Tyler Safran
{"title":"Aesthetic Submandibular Gland Resection: A Review of Complication Incidence and Prevention.","authors":"Sara B A Morel, Luis H Macias, Ritu Chopra, Joshua Vorstenbosch, Tyler Safran","doi":"10.1093/asj/sjaf096","DOIUrl":"https://doi.org/10.1093/asj/sjaf096","url":null,"abstract":"<p><p>Achieving optimal neck contour during facial rejuvenation may require addressing the submandibular glands, as supraplatysmal fat removal alone is insufficient for many patients, particularly those with fuller necks. The purpose of this study is to review the rate of complications associated with removal and techniques to improve safety. A comprehensive search was conducted to identify literature on complications associated with submandibular gland removal in the context of facial rejuvenation. Studies were included if they provided patient data and complication rates following surgical outcomes. Screening of 908 articles identified 11 (1.21%) studies on complication rates related to submandibular gland resection for aesthetic purposes. A total of 3379 participants were included, of which 48.86% (n=1651) underwent submandibular gland resection, with a mean age of 50.4 years (range 32-83), and 88.53% (n=247) were female. Complications included hematomas (1.15%, n=16), requiring reoperation in 23.08% (n=3) of cases, sialoceles (1.33%, n=21), salivary fistulas (0.82%, n=6), nerve injury (3.97%, n=40), xerostomia (0.13%, n=1), and neck induration (21.43%, n=21), with complication rates varying across studies. Submandibular gland reduction offers aesthetic benefits but comes with potential risks. Effective preoperative planning, meticulous gland mobilization, and proper exposure are essential for minimizing risks. Advances in techniques, such as improved dissection methods, the use of botulinum toxin, netting techniques, and energy-based instruments like LigaSure, have enhanced the safety of the procedure. While complications can arise, they typically resolve within a few months, and the overall outcomes improve with surgical experience. The associated risks and benefit profile should be discussed thoroughly with patients.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-surgical Pyoderma Gangrenosum in Breast Surgery: An Updated Systematic Review, Takeaways, and the 6 Commandments. 乳房手术后坏疽性脓皮病:最新的系统综述,要点和6条戒律。
IF 3 2区 医学
Aesthetic Surgery Journal Pub Date : 2025-05-26 DOI: 10.1093/asj/sjaf095
Giorgio Caddia, Delphine Voulliaume, Laura Dettori, Corrado Rubino, Emmanuel Delay
{"title":"Post-surgical Pyoderma Gangrenosum in Breast Surgery: An Updated Systematic Review, Takeaways, and the 6 Commandments.","authors":"Giorgio Caddia, Delphine Voulliaume, Laura Dettori, Corrado Rubino, Emmanuel Delay","doi":"10.1093/asj/sjaf095","DOIUrl":"https://doi.org/10.1093/asj/sjaf095","url":null,"abstract":"<p><strong>Background: </strong>Post-surgical pyoderma gangrenosum (PSPG) is a rare and under-recognized inflammatory dermatosis that can develop after surgery. When it occurs following breast procedures, its clinical presentation often mimics surgical site infection or necrosis, leading to delayed diagnosis and inappropriate treatment, with potentially severe aesthetic and functional consequences.</p><p><strong>Objectives: </strong>To update the literature on PSPG following reconstructive and aesthetic breast surgery and to provide clinicians with practical tools for early recognition and management, including clinical red flags, a diagnostic framework, and therapeutic guidelines.</p><p><strong>Methods: </strong>A systematic review was conducted in March 2025 according to PRISMA guidelines, updating the work of Ehrl et al. by including studies published from 2017 onward. Data from 65 new cases were extracted and analyzed descriptively. We also report three institutional cases and one case of recurrence to provide additional clinical insight.</p><p><strong>Results: </strong>A total of 65 new PSPG cases were identified across 45 studies, for a cumulative total of 152. Reduction mammoplasty was the most frequent surgical trigger. The condition involved multiple sites in 71.4% of combined breast-abdominal procedures. Pain was the most common symptom (86.2%), and the nipple-areola complex was spared in 80.7% of cases. C-reactive protein was often elevated (>200 mg/L), and microbiological cultures were negative in 76.9% of cases. Systemic corticosteroids were the most effective treatment. Mean healing time was 4.5 months; surgical reconstruction was needed in 29% of cases.</p><p><strong>Conclusions: </strong>PSPG remains a diagnostic challenge with significant consequences if unrecognized. Key clues include exaggerated postoperative pain, NAC sparing, elevated CRP, and poor response to antibiotics. We propose a practical flowchart and summarize six core management principles. Preoperative counseling and informed consent, particularly in reduction mammoplasty, should include this rare but serious complication.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aesthetic Surgery Journal Welcomes the Kuwait Plastic Surgery Society. 美容外科杂志欢迎科威特整形外科协会。
IF 3 2区 医学
Aesthetic Surgery Journal Pub Date : 2025-05-23 DOI: 10.1093/asj/sjaf087
Hisham Burezq, Jeffrey M Kenkel
{"title":"Aesthetic Surgery Journal Welcomes the Kuwait Plastic Surgery Society.","authors":"Hisham Burezq, Jeffrey M Kenkel","doi":"10.1093/asj/sjaf087","DOIUrl":"https://doi.org/10.1093/asj/sjaf087","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strategic Use of the V-Shaped Columella- Labial Incision for Reconstructive Rhinoplasty in Severely Compromised Noses. v型鼻小柱唇切口在重度鼻部再造术中的策略性应用。
IF 3 2区 医学
Aesthetic Surgery Journal Pub Date : 2025-05-23 DOI: 10.1093/asj/sjaf060
Amir A Sazgar, Mehr A Sazgar, Rojan Zarei, Amir K Sazgar
{"title":"Strategic Use of the V-Shaped Columella- Labial Incision for Reconstructive Rhinoplasty in Severely Compromised Noses.","authors":"Amir A Sazgar, Mehr A Sazgar, Rojan Zarei, Amir K Sazgar","doi":"10.1093/asj/sjaf060","DOIUrl":"https://doi.org/10.1093/asj/sjaf060","url":null,"abstract":"<p><strong>Background: </strong>Columellar incision techniques for multiply operated and/or severely compromised noses are critical in reconstructive rhinoplasty, because they impact both the final outcome and the risk of complications, such as wound dehiscence and skin flap necrosis.</p><p><strong>Objectives: </strong>The aims of the study are to evaluate the safety of the columella-labial incision in patients with previous mid-columellar scars and assess the functional and aesthetic outcomes of reconstructive septorhinoplasty using this strategic incision through patient-reported outcome measures and chart reviews.</p><p><strong>Methods: </strong>This case series included patients with previous unsuccessful rhinoplasties and mid-columellar scars who underwent open-approach reconstructive septorhinoplasty with a columella-labial incision. Collected data included demographics, medical history, operative reports, and postoperative events. Skeletal reconstruction was performed using various autografts. The Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS) was administered preoperatively and 1 year postoperatively.</p><p><strong>Results: </strong>Most patients were female (68/91, 75%), with a mean age of 37.6 years and 1.74 previous rhinoplasties. The average surgery duration was 239.5 min. Autografts included auricular cartilage (64), costal cartilage (43), temporal fascia (12), and rectus fascia (24). No cases of dehiscence or vascular complications occurred, even in patients with multiple previous mid-columellar incisions. SCHNOS scores significantly improved, with obstruction scores decreasing from 52.86 to 18.43 (standard deviation [SD] = 8.33 vs 3.95) and cosmesis scores from 78.09 to 20.19 (SD = 6.44 vs 5.13).</p><p><strong>Conclusions: </strong>The V-shaped columella-labial incision does not increase the risk of vascular compromise, even in patients with mid-columellar scars. Its strategic use facilitates skeletal reconstruction while effectively improving nasal contour and columellar length with acceptable scarring.</p><p><strong>Level of evidence: 4 (therapeutic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perception of Changes in Functional Symptoms and Psychological Aspects Related to Rectus Muscle Diastasis in Women Who Have Undergone Reparative Abdominoplasty. 修复性腹部成形术妇女与直肌移位相关的功能症状和心理方面的变化
IF 3 2区 医学
Aesthetic Surgery Journal Pub Date : 2025-05-23 DOI: 10.1093/asj/sjaf057
Giovanni Francesco Marangi, Marco Gratteri, Fara Desiree Romano, Vito Toto, Angelo Faiola, Matteo Pazzaglia, Lucrezia Chiacchierini, Alessandro Cocomazzi, Annalisa Cogliandro, Paolo Persichetti
{"title":"Perception of Changes in Functional Symptoms and Psychological Aspects Related to Rectus Muscle Diastasis in Women Who Have Undergone Reparative Abdominoplasty.","authors":"Giovanni Francesco Marangi, Marco Gratteri, Fara Desiree Romano, Vito Toto, Angelo Faiola, Matteo Pazzaglia, Lucrezia Chiacchierini, Alessandro Cocomazzi, Annalisa Cogliandro, Paolo Persichetti","doi":"10.1093/asj/sjaf057","DOIUrl":"https://doi.org/10.1093/asj/sjaf057","url":null,"abstract":"<p><strong>Background: </strong>Very little is known of how urinary symptoms and low back pain related to rectus abdominis diastasis tend to change after reparative surgery.</p><p><strong>Objectives: </strong>In this study we aimed to investigate these symptom changes in women who underwent abdominoplasty with diastasis correction, and also provide an overview on quality of life, psychosocial aspects, and patient satisfaction.</p><p><strong>Methods: </strong>A total of 78 patients underwent abdominoplasty with diastasis repair and were included in this prospective study. Urinary symptoms and low back pain were evaluated respectively by the International Consultation on Incontinence Questionnaire, Female Lower Urinary Tract Symptoms Modules (ICIQ-FLUTS) and the Roland-Morris questionnaire. The Derriford Appearance Scale (DAS-59) was administered for evaluation of the respondent's discomfort, as was the BODY-Q for body image and quality of life. Furthermore, the assessment of satisfaction by 3 external surgeons was obtained. Statistical analysis was conducted with Prism 9.</p><p><strong>Results: </strong>Statistically significant differences between time T0 (preoperative) and T3 (3 months postoperatively) and between time T0 and T12 (12 months postoperatively) were found for the BODY-Q, ICIQ-FLUTS, and Roland-Morris scores. No correlation was found between diastasis width and the difference from T0 to T12 in any of the symptom questionnaires. A correlation between patient and surgeon satisfaction emerged. In just 9 cases the patient was dissatisfied when the expert observer was satisfied. The mean preoperative DAS-59 value of satisfied patients and satisfied surgeons was compared with that of dissatisfied patients and satisfied surgeons, and a statistically significant difference was noted.</p><p><strong>Conclusions: </strong>Abdominoplasty with correction of rectus muscle diastasis may improve women's quality of life. From the patient's point of view, voiding and incontinence symptoms and back pain tended to improve after surgery regardless of the width of the diastasis.</p><p><strong>Level of evidence: 3 (therapeutic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Retrospective Case Series Study of Illegal Cosmetic Iatrogenic Botulism: Outbreak Analysis and Response Lessons. 非法美容医源性肉毒杆菌中毒的回顾性病例系列研究:爆发分析和应对经验教训。
IF 3 2区 医学
Aesthetic Surgery Journal Pub Date : 2025-05-20 DOI: 10.1093/asj/sjaf088
He Qiu, Jiang Shen, Yali Tang, Qiang Ji, Xiaoqun Lin, Dongmei Wu
{"title":"A Retrospective Case Series Study of Illegal Cosmetic Iatrogenic Botulism: Outbreak Analysis and Response Lessons.","authors":"He Qiu, Jiang Shen, Yali Tang, Qiang Ji, Xiaoqun Lin, Dongmei Wu","doi":"10.1093/asj/sjaf088","DOIUrl":"https://doi.org/10.1093/asj/sjaf088","url":null,"abstract":"<p><strong>Background: </strong>Botulism is a rare and possibly life-threatening neuroparalytic syndrome. Recent large-scale outbreaks of iatrogenic botulism, primarily linked to cosmetic injections, have garnered significant attention.</p><p><strong>Objectives: </strong>This study discusses the factors that may lead to the outbreak of cosmetic iatrogenic botulism (CIB), provides the epidemiological description of CIB cases and puts forward response measures.</p><p><strong>Methods: </strong>All clinical data, laboratory investigations, and therapeutic procedures of CIB patients in a large single-center retrospective cohort (2014-2024) were reviewed and analyzed.</p><p><strong>Results: </strong>Over a 10 year period, 161 cases of CIB were identified, of which 81 (50.31%) were hospitalized and 80 (49.69%) were outpatient cases. Most patients received botulinum toxin (BoNT) injections of unknown origin from unlicensed practitioners in non-medical settings. Severe and moderate cases of CIB accounted for up to 60%, with the majority of outbreaks occurring in 2024. The median time from botulism onset was 0 to 17 days, with the highest incidence occurring within 3 days following the injection. Hospitalized patients were discharged after a mean of 11.64 ± 9.40 days (range: 1 to 39 days), and symptoms resolved in botulism patients within a mean of 24.85 ± 11.67 days following treatment. Treatments included antitoxin administration, hyperbaric oxygen therapy, pyridostigmine, other symptomatic treatment and supportive care.</p><p><strong>Conclusions: </strong>This represents the largest reported outbreak of illicit CIB worldwide, highlighting the risks associated with counterfeit BoNT, non-compliant practices, and underscoring the critical need for stringent surveillance of BoNT distribution. Clinicians should be adept at recognizing and adhering to the diagnosis, treatment, and follow-up management of CIB.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility of an AI-driven Classification of Tuberous Breast Deformity: A Siamese Network Approach with a Continuous Tuberosity Score. 人工智能驱动的结节性乳房畸形分类的可行性:连续结节评分的暹罗网络方法。
IF 3 2区 医学
Aesthetic Surgery Journal Pub Date : 2025-05-20 DOI: 10.1093/asj/sjaf090
Stefano Vaccari, Alberto Paderno, Simone Furlan, Mattia Federico Cavallero, Alessandro Marco Lupacchini, Riccardo Di Giuli, Marco Klinger, Francesco Klinger, Valeriano Vinci
{"title":"Feasibility of an AI-driven Classification of Tuberous Breast Deformity: A Siamese Network Approach with a Continuous Tuberosity Score.","authors":"Stefano Vaccari, Alberto Paderno, Simone Furlan, Mattia Federico Cavallero, Alessandro Marco Lupacchini, Riccardo Di Giuli, Marco Klinger, Francesco Klinger, Valeriano Vinci","doi":"10.1093/asj/sjaf090","DOIUrl":"https://doi.org/10.1093/asj/sjaf090","url":null,"abstract":"<p><strong>Background: </strong>Tuberous breast deformity (TBD) is a congenital condition characterized by constriction of the breast base, parenchymal hypoplasia, and areolar herniation. The absence of a universally accepted classification system complicates diagnosis and surgical planning, leading to variability in clinical outcomes. Artificial intelligence (AI) has emerged as a powerful adjunct in medical imaging, enabling objective, reproducible, and data-driven diagnostic assessments.</p><p><strong>Objectives: </strong>This study introduces an AI-driven diagnostic tool for tuberous breast deformity (TBD) classification using a Siamese Network trained on paired frontal and lateral images. Additionally, the model generates a continuous Tuberosity Score (ranging from 0 to 1) based on embedding vector distances, offering an objective measure to enhance surgical planning and improved clinical outcomes.</p><p><strong>Methods: </strong>A dataset of 200 expertly classified frontal and lateral breast images (100 tuberous, 100 non-tuberous) was used to train a Siamese Network with contrastive loss. The model extracted high-dimensional feature embeddings to differentiate tuberous from non-tuberous breasts. Five-fold cross-validation ensured robust performance evaluation. Performance metrics included accuracy, precision, recall, and F1-score. Visualization techniques, such as t-SNE clustering and occlusion sensitivity mapping, were employed to interpret model decisions.</p><p><strong>Results: </strong>The model achieved an average accuracy of 96.2% ± 5.5%, with balanced precision and recall. The Tuberosity Score, derived from the Euclidean distance between embeddings, provided a continuous measure of deformity severity, correlating well with clinical assessments.</p><p><strong>Conclusions: </strong>This AI-based framework offers an objective, high-accuracy classification system for TBD. The Tuberosity Score enhances diagnostic precision, potentially aiding in surgical planning and improving patient outcomes.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measuring Satisfaction With Minimally Invasive Aesthetic Treatments With the SKIN-Q Treatment Outcome Scale. 用SKIN-Q治疗结果量表测量微创美容治疗满意度。
IF 3 2区 医学
Aesthetic Surgery Journal Pub Date : 2025-05-20 DOI: 10.1093/asj/sjaf075
Anne F Klassen, Charlene Rae, Lucas Gallo, Stefan Cano, Manraj Kaur, Steven Dayan, Katie Armstrong, Lotte Poulsen, Elena Tsangaris, Katherine B Santosa, Andrea L Pusic
{"title":"Measuring Satisfaction With Minimally Invasive Aesthetic Treatments With the SKIN-Q Treatment Outcome Scale.","authors":"Anne F Klassen, Charlene Rae, Lucas Gallo, Stefan Cano, Manraj Kaur, Steven Dayan, Katie Armstrong, Lotte Poulsen, Elena Tsangaris, Katherine B Santosa, Andrea L Pusic","doi":"10.1093/asj/sjaf075","DOIUrl":"https://doi.org/10.1093/asj/sjaf075","url":null,"abstract":"<p><strong>Background: </strong>A key outcome in aesthetic treatments is the patient's view of how their skin looks and feels after a treatment.</p><p><strong>Objectives: </strong>To add a Treatment Outcome scale to the SKIN-Q patient-reported outcome measure.</p><p><strong>Methods: </strong>Concept elicitation interviews were performed with patients recruited from clinics in Canada and the USA. Data were coded, analyzed, and used to draft a Treatment Outcome scale. The scale was refined with patient and expert feedback and field tested in an online sample (i.e., Prolific). Rasch measurement and classical test theory psychometric analyses were performed to examine scale reliability and validity.</p><p><strong>Results: </strong>The concept elicitation interviews included 26 participants. The first draft of the Treatment Outcome scale included 32 items that assessed changes in appearance (e.g., look better) and wellbeing (e.g., feel more confident). Items were revised with input from 12 experts, 11 patients, and 174 online participants who had aesthetic face and/or body treatments and provided 180 survey responses, resulting in 36 items. Prolific data were collected from 499 participants who provided 542 assessments. The sample comprised 80.6% women; 78.8% had a facial treatment, 11.4% had a body treatment, and 9.8% had both a facial and body treatment. Data for a final 10-item Treatment Outcome scale fit the Rasch model (Chi-square = 50.46, df=40, p=0.124). The scale evidenced high reliability, with a person separation index and Cronbach alpha values >0.87. A total of 20/22 (91%) pre-defined construct validation hypotheses were accepted. A total of 136 participants completed the Treatment Outcome scale a second time within 7-14 days. The intraclass correlation coefficient for the test-retest was 0.89 (95% CI 0.85, 0.92).</p><p><strong>Conclusions: </strong>This new SKIN-Q scale can be used alongside other patient-centered outcome tools to measure how patients look and feel after minimally invasive aesthetic treatments for the body and/or face.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Safety and Effectiveness of Cold-Crosslinked Hyaluronic Acid Fillers: Multicenter, Randomized, Controlled, Double-Blind Study. 冷交联透明质酸填充剂的长期安全性和有效性:多中心、随机、对照、双盲研究。
IF 3 2区 医学
Aesthetic Surgery Journal Pub Date : 2025-05-16 DOI: 10.1093/asj/sjaf080
Michael S Kaminer, Rui L Avelar, Leslie Baumann, Valerie Callender, Steven H Dayan, Jeremy B Green, Steven K Grekin, Sebastien Guyon
{"title":"Long-Term Safety and Effectiveness of Cold-Crosslinked Hyaluronic Acid Fillers: Multicenter, Randomized, Controlled, Double-Blind Study.","authors":"Michael S Kaminer, Rui L Avelar, Leslie Baumann, Valerie Callender, Steven H Dayan, Jeremy B Green, Steven K Grekin, Sebastien Guyon","doi":"10.1093/asj/sjaf080","DOIUrl":"https://doi.org/10.1093/asj/sjaf080","url":null,"abstract":"<p><strong>Background: </strong>EVOLYSSE FORM (EVLF) and EVOLYSSE SMOOTH (EVLS) are new hyaluronic acid fillers created using an innovative cold crosslinking process.</p><p><strong>Objectives: </strong>To collect safety and effectiveness data on new cold-crosslinked fillers to support US approval for the correction of moderate to severe dynamic facial wrinkles and folds.</p><p><strong>Methods: </strong>In this randomized, controlled, split-face study, 140 subjects with moderate to severe nasolabial folds received a cold-crosslinked filler in 1 nasolabial fold (EVLF = 70, EVLS = 70) and a traditionally-crosslinked filler, Restylane-L (RESL), in the contralateral fold and were followed through 12 months with an optional retreatment at that timepoint and subsequent 3 months of safety follow-up.</p><p><strong>Results: </strong>The primary endpoint of mean Wrinkle Severity Rating Scale change from baseline to Month 6 as rated by photographic review panel demonstrated non-inferiority and statistical superiority for the cold-crosslinked fillers. Blinded evaluator Wrinkle Severity Rating Scale assessments showed a mean change from baseline that was statistically significantly better than RESL for EVLF at all visits through 12 months and for EVLS at 6 and 9 months. Most subjects were responders on the Global Aesthetic Improvement Scale throughout the study according to ratings by blinded evaluators, treating investigators, and subjects. The FACE-Q Appraisal of Nasolabial Folds overall mean score showed significant improvement from baseline (p < 0.0001) at all timepoints through Month 12 for all treatment groups. All treatments were well tolerated.</p><p><strong>Conclusions: </strong>The new cold-crosslinked fillers were shown to be safe and effective for correction of nasolabial folds, with results lasting for 1 year.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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