Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering最新文献_第4页

Influence of a fat on muscle oxygenation measurement using near-IR spectroscopy: quantitative analysis based on two-layered phantom experiments and Monte Carlo simulation. 脂肪对近红外光谱测量肌肉氧合的影响:基于双层模型实验和蒙特卡罗模拟的定量分析。

Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering Pub Date : 2000-01-01 DOI: 10.1163/15685570052061531

L Lin, M Niwayama, T Shiga, N Kudo, M Takahashi, K Yamamoto

{"title":"Influence of a fat on muscle oxygenation measurement using near-IR spectroscopy: quantitative analysis based on two-layered phantom experiments and Monte Carlo simulation.","authors":"L Lin, M Niwayama, T Shiga, N Kudo, M Takahashi, K Yamamoto","doi":"10.1163/15685570052061531","DOIUrl":"https://doi.org/10.1163/15685570052061531","url":null,"abstract":"The influence of a subcutaneous fat layer on measurement of muscle oxygenation using near-IR spectroscopy was quantitatively investigated by two-layered phantom experiments and Monte Carlo simulations, with the aim of developing an algorithm that can correct this influence. The phantom consisted of a fat-like layer, which was a mixture of agar and titanium dioxide powder, and a muscle-like layer, which was suspension of washed bovine blood in Intralipid solution. An LED with 760 and 840 nm elements was used as an optical source, and the backscattered light was detected by photodiodes at source-detector distances of 20, 30 and 40 mm. The relationships between changes in optical density and blood concentrations were obtained at fat-like layer thicknesses of 0.5,10 and 15 mm under fully oxygenated and fully deoxygenated states. It was experimentally found that the change in optical density is significantly decreased and the linearity of measurement characteristics is clearly distorted by the presence of a fat layer. In the simulations, normalized light reflectance and mean optical pathlength in a muscle layer were calculated. The simulation results of the light reflectance agreed well with the experimental results. When the absorption in a muscle layer was relatively high, the mean optical pathlength in the muscle layer, or the measurement sensitivity, was not so dependent on the absorption. Therefore, the modified Beer-Lambert law can still be applied to estimate changes in muscle absorption from changes in optical density, even when a fat layer is involved. The results of simulation also suggested that the influence of a fat layer can be eliminated by correcting the measurement sensitivity using the fat layer thickness.","PeriodicalId":77139,"journal":{"name":"Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering","volume":"10 1","pages":"43-58"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1163/15685570052061531","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21739326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 29

Automatic detection of open and closed eye states in the electroencephalographic (EEG) record for background EEG interpretation by the trigger method. 利用触发法自动检测脑电图记录中的睁眼和闭眼状态，用于背景脑电图解释。

Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering Pub Date : 2000-01-01 DOI: 10.1163/15685570052061504

O Bai, M Nakamura, A Ikeda, H Shibasaki

{"title":"Automatic detection of open and closed eye states in the electroencephalographic (EEG) record for background EEG interpretation by the trigger method.","authors":"O Bai, M Nakamura, A Ikeda, H Shibasaki","doi":"10.1163/15685570052061504","DOIUrl":"https://doi.org/10.1163/15685570052061504","url":null,"abstract":"Automatic detection of open and closed eye states in electroencephalographic (EEG) records was investigated in this study as a part of procedures for the precise interpretation of the background EEG to achieve a comprehensive automatic EEG interpretation system. The features of eye open and closure were extracted from the EEG using a Markov process amplitude (MPA) EEG model, which could efficiently express the features of the EEG using a small number of parameters. A new technique, named the trigger method, was also developed to overcome the difficulty resulting from large differences in the EEG features among different subjects, because an accurate detection could not be obtained by using the conventional threshold method. The proposed method gave satisfactory results which conformed with those of visual inspection by a qualified EEGer and could be clinically used as a preprocessing method for the automatic interpretation of the awake background EEG.","PeriodicalId":77139,"journal":{"name":"Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering","volume":"10 1","pages":"1-15"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1163/15685570052061504","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21739323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

New polymeric biomaterials-phospholipid polymers with a biocompatible surface. 新型高分子生物材料——具有生物相容性表面的磷脂聚合物。

Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering Pub Date : 2000-01-01 DOI: 10.1163/15685570052061946

K Ishihara

{"title":"New polymeric biomaterials-phospholipid polymers with a biocompatible surface.","authors":"K Ishihara","doi":"10.1163/15685570052061946","DOIUrl":"https://doi.org/10.1163/15685570052061946","url":null,"abstract":"New biomedical polymers were designed with attention to the surface of biological membranes, i.e. the surface was completely covered with phospholipid polar groups. The polymers with a phosphorylcholine group, 2-methacryloyloxyethyl phosphorylcholine (MPC) co-polymerized with hydrophobic alkyl group, could interact with phospholipids in plasma selectively and strongly. The adsorbed phospholipids on the polymer surface were concentrated, organized each other and then formed a self-assembled biomimetic membrane surface. The surface showed excellent resistance for both protein adsorption and blood cell adhesion, i.e. the MPC polymer showed good blood compatibility. Based on these characteristics of the MPC polymer, it was applied to improve the biocompatibility and biostability of an implantable glucose sensor. The relative output current of the sensor covered with the MPC polymer membrane was maintained as the initial level even after 14 days of subcutaneous implantation in a rat. Therefore, it is concluded that the MPC polymer membrane is an excellent material for implantable biomedical devices.","PeriodicalId":77139,"journal":{"name":"Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering","volume":"10 2","pages":"83-95"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1163/15685570052061946","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21740039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 30

Oximetric and capnometric studies--aspects of natural and artificial ventilation. 血氧计和碳热计研究——自然和人工通气的方面。

Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering Pub Date : 2000-01-01 DOI: 10.1163/15685570052062585

T Pałko

{"title":"Oximetric and capnometric studies--aspects of natural and artificial ventilation.","authors":"T Pałko","doi":"10.1163/15685570052062585","DOIUrl":"https://doi.org/10.1163/15685570052062585","url":null,"abstract":"Methods and instrumentation of own design and their application to the measurement of oxygen and CO2 content in blood and respiration gases are discussed. Spectrophotometry, particularly double wavelength colorimetry using red light and IR light, applied to the measurement of oxygen blood saturation for in vitro examination and through an intravascular catheter for invasive in vivo study and by means of pulse oximetry for non-invasive in vivo examination are presented. The electrochemical methods applied to in vitro and in vivo measurement of oxygen in blood (amperometric method) and in respiration gases (amperometric and fuel cell methods) are discussed. The electrochemical Stow-Severinghaus method of CO2 tension measurement in blood and CO2 partial pressure in respiratory gases as well as the selective IR light (4.26 microm) absorption method and instruments of own design for CO2 measurements in respiratory gases are also discussed. The methods and instrumentation described are very important for monitoring respiratory and circulatory function, particularly during artificial ventilation and circulatory support.","PeriodicalId":77139,"journal":{"name":"Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering","volume":"10 3","pages":"185-98"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1163/15685570052062585","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21846642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Surface pitting of heart valve disks tested in an accelerated fatigue tester. 在加速疲劳试验机上对心脏瓣膜表面点蚀的试验。

Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering Pub Date : 2000-01-01 DOI: 10.1163/15685570052062567

H Lee, T Shimooka, Y Mitamura, K Yamamoto, T Yuhta

引用次数: 10

Heart and lung support interaction--modeling and simulation. 心肺支持相互作用——建模和仿真。

Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering Pub Date : 2000-01-01 DOI: 10.1163/15685570052062648

M Darowski

{"title":"Heart and lung support interaction--modeling and simulation.","authors":"M Darowski","doi":"10.1163/15685570052062648","DOIUrl":"https://doi.org/10.1163/15685570052062648","url":null,"abstract":"Mechanical support of the lungs used to preserve life or during any kind of surgery may have an adverse effect on the cardiovascular system. Usually, positive pressure in alveoli diminishes lung perfusion, venous return and cardiac output. Positive pressure during the respiratory cycle is transfered into the thoracic space. The aim of this study was to assess how synchronization of the respirator with spontaneous breathing influences the distribution of pressure and ventilation in nonhomogeneous lungs and how it should influence hemodynamics. For this purpose a multicompartmental model of respiratory system mechanics was used in the electrical analog of a respirator-lung circuit, which enabled us to simultaneously simulate ventilatory support and spontaneous breathing. Mechanical properties of the respiratory system were modeled by lumped parameters: resistances and capacitances of constant values, independent of lung volume or inspiratory flow changes. A multicompartmental model of the respiratory system enabled us to simulate lung pathology characterized by non-homogeneity of the mechanical properties of the different parts of the lungs. The results of simulations presented in the paper enable us to conclude that lung volume increase, independent of the respirator-patient breathing synchronization, may be modeled as the increase in pulmonary vascular resistance and alveolar pressure increase, dependent on respirator-patient breathing synchronization, may be averaged by esophageous balloon measurements which show intrathoracic pressure changes.","PeriodicalId":77139,"journal":{"name":"Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering","volume":"10 3","pages":"157-65"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1163/15685570052062648","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21846639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Artificial ventilation of the lungs for emergencies. 紧急情况下进行肺部人工通气。

Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering Pub Date : 2000-01-01 DOI: 10.1163/15685570052062576

M Darowski, M Englisz

{"title":"Artificial ventilation of the lungs for emergencies.","authors":"M Darowski, M Englisz","doi":"10.1163/15685570052062576","DOIUrl":"https://doi.org/10.1163/15685570052062576","url":null,"abstract":"The necessity for extraordinary ventilatory support may appear in different places all over the world in cases of a massive disaster (industrial or natural), connected with gas poisoning on a huge scale. Hospitals equipped with limited number of respirators, adequate for peacetime activity, are not able to meet suddenly multiplied requirements for ventilatory support. This paper describes a preliminary study to develop a convenient, reliable method of performing artificial ventilation of at least two patient by means of only one ventilator. We developed a unique, new control system (patent pending) which, when placed between a respirator and endotracheal tubes of the patients, divides the total tidal volume between the patients' lungs and controls pressures at their airways. A special arrangement of valves in the control system enables us to separate inspiratory and expiratory paths for each patient and to avoid cross-infection. The model study performed, according to ISO standards, on mechanical test lungs has shown that the proposed control system enables us to adjust ventilatory parameters at desired values, when lung compliance or respiratory airway resistance differ. The proposed one-source artificial ventilation is a simple solution to provide ventilatory support when the number of patients is greater than the number of respirators that are available.","PeriodicalId":77139,"journal":{"name":"Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering","volume":"10 3","pages":"177-83"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1163/15685570052062576","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21846641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Acquisition and analysis of brainstem auditory evoked responses of normal and diseased subjects by spectral estimation. 用谱估计法获取和分析正常和病变受试者的脑干听觉诱发反应。

Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering Pub Date : 2000-01-01 DOI: 10.1163/15685570052061559

H C Nagaraj, S Radhakrishnan, S Srinivasan, T R Swaminathan

{"title":"Acquisition and analysis of brainstem auditory evoked responses of normal and diseased subjects by spectral estimation.","authors":"H C Nagaraj, S Radhakrishnan, S Srinivasan, T R Swaminathan","doi":"10.1163/15685570052061559","DOIUrl":"https://doi.org/10.1163/15685570052061559","url":null,"abstract":"Human brainstem auditory evoked responses (BAERs) are sensory evoked potentials that can be recorded within a few milliseconds following a transient acoustic stimulus (click signal). This paper suggests a novel technique to clearly demarcate normals and patients with complaints of vertigo and deafness by computing hitherto unused power spectral parameters from the BAER signals recorded on them. The BAER spectrum of normal subjects contains three main frequency components, i.e. low-, mid- and high-frequency components around 100, 500 and 1000 Hz, respectively, which is not so in the case of diseased subjects. The spectral parameters, i.e. the mean power frequency, median frequency, the ratios of the integrated power at dominant frequencies to that of the total power in spectrum and change in spectral power (CP) between these dominant frequency components are used to classify the recorded BAER signals into those of normals and the patients, and aid the clinician in quick and better diagnosis. The ranges of CP are estimated for the different groups and appear to be the most dominant parameter in the classification of the BAER signals.","PeriodicalId":77139,"journal":{"name":"Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering","volume":"10 1","pages":"67-75"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1163/15685570052061559","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21739328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Super-elastic property of Ti-Ni alloy for use in dentistry. 牙科用钛镍合金的超弹性性能。

Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering Pub Date : 2000-01-01 DOI: 10.1163/15685570052061955

T Yoneyama, H Doi, E Kobayashi, H Hamanaka

引用次数: 4

Interaction between tissues and implantable materials. 组织与植入材料之间的相互作用。

Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering Pub Date : 2000-01-01 DOI: 10.1163/15685570052061937

M Lewandowska-Szumieł, J Komender

引用次数: 11