Age and ageingPub Date : 2025-03-03DOI: 10.1093/ageing/afaf068
Omar Ammous, Dawid Pieper, Petra Thürmann, Tim Mathes
{"title":"Potentially inappropriate medication lists for older people: a review of methods applied to the development.","authors":"Omar Ammous, Dawid Pieper, Petra Thürmann, Tim Mathes","doi":"10.1093/ageing/afaf068","DOIUrl":"https://doi.org/10.1093/ageing/afaf068","url":null,"abstract":"<p><strong>Introduction: </strong>With a growing older population and an increasing prevalence of age-related health conditions, inappropriate prescription (IP) has become a concern in public health. Potentially Inappropriate Medication (PIM) lists were developed to address issues related to IP in the older population.</p><p><strong>Objectives: </strong>Systematically compare the approaches adopted to develop PIM lists.</p><p><strong>Methods: </strong>We searched MEDLINE (06/02/22) and reference lists of eligible studies, and we included the most recent version of explicit PIM lists published from 1990 onwards in English or German. Two reviewers performed the screening, and one extracted the data. A second reviewer double-checked 20% of the data extraction. We identified key approaches and synthesised them narratively.</p><p><strong>Results: </strong>We included 31 PIM lists, consisting of new lists (N = 18) or updates (N = 8), adjustments-validation (N = 3) and extensions of old lists (N = 2).Twenty studies focused on a specific geographic location and five on a particular condition. The others were general lists. The definition of the older population ranged from ≥65 to ≥75 years.The sources explored to determine eligible drugs varied significantly. PubMed was the most searched database, and most studies relied on previously published lists to create their own. Two studies underwent critical appraisal and certainty of evidence assessment.The Delphi was the widely used consensus technique. However, there were extensive variations in the organisation of the first draft, panellist selection, consensus thresholds and the presentation of the final list.</p><p><strong>Conclusion: </strong>Given the variability of the methods used, creating a consensus to standardise the development of PIM lists has become critical.</p>","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"54 3","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Age and ageingPub Date : 2025-03-03DOI: 10.1093/ageing/afaf061
Katy Jenks, Jennifer Kirsty Burton
{"title":"Linking data to explore variation in care home prescribing: a helpful tool for starting conversations to enable change.","authors":"Katy Jenks, Jennifer Kirsty Burton","doi":"10.1093/ageing/afaf061","DOIUrl":"https://doi.org/10.1093/ageing/afaf061","url":null,"abstract":"","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"54 3","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Age and ageingPub Date : 2025-03-03DOI: 10.1093/ageing/afaf045
Frank F Huang, Jitong Liang, Chung-Ying Lin, Dino Samartzis, Jaro Karppinen, Yongping Zheng, Zhixing Zhou, Daniel K Y Zheng, Jeremy R Chang, Katie de Luca, Arnold Y L Wong
{"title":"Measurement properties of self-reported outcome measures for older adults with nonspecific low back pain: a systematic review.","authors":"Frank F Huang, Jitong Liang, Chung-Ying Lin, Dino Samartzis, Jaro Karppinen, Yongping Zheng, Zhixing Zhou, Daniel K Y Zheng, Jeremy R Chang, Katie de Luca, Arnold Y L Wong","doi":"10.1093/ageing/afaf045","DOIUrl":"10.1093/ageing/afaf045","url":null,"abstract":"<p><strong>Objective: </strong>To summarise the measurement properties of patient-reported outcome measures (PROMs) for older adults with nonspecific low back pain.</p><p><strong>Methods: </strong>Eight databases were searched from inception to January 2024. Two independent reviewers conducted article screening, data extraction, risk of bias assessments, evaluations of measurement properties of PROMs, syntheses of quality of evidence and forming recommendation levels using relevant checklists and assessment tools.</p><p><strong>Results: </strong>Ten PROMs were identified from 12 included studies. The Functional Rating Index, Oswestry Disability Index, Roland Morris Disability Questionnaire and Quebec Back Pain Disability Scale demonstrated the highest recommendation (category A: PROM most suitable) for evaluating pain-related functional limitation or pain intensity in older adults with acute, subacute or chronic nonspecific low back pain. The Pain Response to Activity and Positioning questionnaire obtained a category A recommendation for making a differential diagnosis of chronic nonspecific low back pain in older adults. The 36-Item World Health Organization Disability Assessment Schedule 2.0 was considered promising (category B: PROM recommended) for assessing physical functioning, while the Back Believe Questionnaire, Catastrophizing Avoidance Scale D-65+, Pain Catastrophizing Scale and Psychological Inflexibility in Pain Scale obtained category B recommendation for evaluating negative thoughts in this population, although further validation is warranted.</p><p><strong>Conclusions: </strong>This systematic review identified suitable PROMs for assessing physical function in older adults with nonspecific low back pain, but more studies are needed to evaluate the measurement properties of questionnaires on other outcome domains in this population.</p>","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"54 3","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11942786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Age and ageingPub Date : 2025-03-03DOI: 10.1093/ageing/afaf071
{"title":"Correction to: Effects of osteoporosis treatment and multicomponent integrated care on intrinsic capacity and happiness among rural community-dwelling older adults: the Healthy Longevity and Ageing in Place (HOPE) randomised controlled trial.","authors":"","doi":"10.1093/ageing/afaf071","DOIUrl":"10.1093/ageing/afaf071","url":null,"abstract":"","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"54 3","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Age and ageingPub Date : 2025-03-03DOI: 10.1093/ageing/afaf059
{"title":"Correction to: The British Geriatrics Society's position on assisted dying.","authors":"","doi":"10.1093/ageing/afaf059","DOIUrl":"https://doi.org/10.1093/ageing/afaf059","url":null,"abstract":"","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"54 3","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Age and ageingPub Date : 2025-03-03DOI: 10.1093/ageing/afaf065
Roy L Soiza
{"title":"Editor's view-political interference, assisted dying and multicomponent interventions.","authors":"Roy L Soiza","doi":"10.1093/ageing/afaf065","DOIUrl":"https://doi.org/10.1093/ageing/afaf065","url":null,"abstract":"","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"54 3","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Age and ageingPub Date : 2025-02-25DOI: 10.1093/ageing/afaf028
Sarah A Hopkins, Annabel Price, Simon N Etkind
{"title":"Why we need to consider frailty in the assisted dying debate","authors":"Sarah A Hopkins, Annabel Price, Simon N Etkind","doi":"10.1093/ageing/afaf028","DOIUrl":"https://doi.org/10.1093/ageing/afaf028","url":null,"abstract":"Background Assisted dying/assisted suicide (AD/AS) is legal or decriminalised in several countries and Bills to legalise it are currently being considered by the UK and Scottish Parliaments. Older adults living with frailty make up an increasing proportion of those who die, yet the possible implications of AD/AS for these individuals are relatively unexplored. Here, we discuss some of these issues. Discussion Frailty complicates AD/AS in relation to eligibility because of ambiguity over whether frailty constitutes a terminal illness, challenges in accurately predicting prognosis, and difficulty determining reversibility of suffering. Frailty also blurs the distinction between terminal illness and disability, in contrast to the clear-cut language of current proposed legislation where those with a terminal illness are eligible, but those with disability are not. We discuss that decisions regarding AD/AS are often framed in terms of individual autonomy, whereas relational autonomy is the norm for many living with frailty, meaning that concerns regarding implicit coercion need careful consideration. Further, there is an established link between frailty and feeling a burden to others. There is an open question as to whether this, combined with persisting ageist attitudes in society, could influence decisions of people living with frailty about an assisted death. Conclusion The above issues make the place of frailty in proposed legislation on AD/AS uncertain. Further consideration is needed regarding eligibility, safeguards in the context of relational autonomy and for those who already feel a burden, and how to mitigate risks of further entrenching ableist and ageist attitudes.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"1 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143495157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Age and ageingPub Date : 2025-02-25DOI: 10.1093/ageing/afaf029
Rowan H Harwood
{"title":"We should not fear assisted dying","authors":"Rowan H Harwood","doi":"10.1093/ageing/afaf029","DOIUrl":"https://doi.org/10.1093/ageing/afaf029","url":null,"abstract":"The argument for allowing assisted dying (ad) is based on two principles: (i) respect for autonomy and (ii) adequate safeguards to avoid coercion or abuse. We should ensure that ad is accessible, equitable and regulated. It is wrong, without very good reason, to impose a set of beliefs on other people who do not hold those views. We should therefore not impose an obligation to go on living if an individual considers that it is associated with unwanted suffering, distress, dependency, indignity or cost. We should accept, and provide for, diversity and variation in people’s views on ad. The right to refuse life-prolonging therapies, or to have drugs to control distressing symptoms that incidentally shorten life, is well-established. The ethical distinction between these and ad is arguable. Worldwide, most people who choose to end their lives, are already close to death. Some people need protection from the possibility of their lives being ended when they did not intend or want it. However, older people are capable of making informed decisions on serious matters, with or without the support of others. To suggest otherwise is paternalistic and ageist. Multiple jurisdictions worldwide have developed and use effective safeguards. In these countries, ad is mostly welcomed and has not led to undue legal, social or human rights problems. Legal provision for ad is both desirable and necessary.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"12 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143495170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Age and ageingPub Date : 2025-02-23DOI: 10.1093/ageing/afaf033
Anita Wong, Claudia Cooper, Catherine J Evans, Mark James Rawle, Kate Walters, Simon Paul Conroy, Nathan Davies
{"title":"Supporting older people through Hospital at Home care: a systematic review of patient, carer and healthcare professionals’ perspectives","authors":"Anita Wong, Claudia Cooper, Catherine J Evans, Mark James Rawle, Kate Walters, Simon Paul Conroy, Nathan Davies","doi":"10.1093/ageing/afaf033","DOIUrl":"https://doi.org/10.1093/ageing/afaf033","url":null,"abstract":"Introduction Hospital at Home provides hospital-level type care at home, both remote and face-to-face by a multidisciplinary team of healthcare professionals. In practice, various different models are employed, but we do not know what older people, their family carers (carers) and healthcare professionals think of what works best for them. This review aimed to describe the various Hospital at Home models and synthesise literature exploring patient, carer and staff perspectives of Hospital at Home care for older people. Methods and analysis A systematic review of UK studies. Medline, Embase and CINAHL and grey literature were searched from 1991 to 2024, using predetermined inclusion and exclusion criteria; data were extracted from included papers. Tabulation, thematic grouping and concept mapping of themes were used to narratively synthesise the literature. Results Twenty studies met eligibility. Hospital at Home models included admission avoidance and early discharge. Studies were largely positive regarding Hospital at Home, with benefits including home familiarity, enabling person-centred care and shared decision-making and provision of family carer support. Challenges included staff accessibility, patient and carer anxieties regarding the safety of virtual wards, coordination across sectors and older people using technology. Conclusion Provision of holistic, accessible and continuous care for older people in Hospital at Home services facilitated patient and carer empowerment, dignity and autonomy. There are gaps in our understanding and evidence surrounding paid care workers and informal carers’ perspectives in UK settings, especially within rigorous Hospital at Home literature.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"209 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143477570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Age and ageingPub Date : 2025-02-21DOI: 10.1093/ageing/afaf035
Paula Etayo-Urtasun, Mikel L Sáez de Asteasu, Mikel Izquierdo
{"title":"Comparison of hospitalisation settings and exercise interventions in acute care: a systematic review and meta-analysis","authors":"Paula Etayo-Urtasun, Mikel L Sáez de Asteasu, Mikel Izquierdo","doi":"10.1093/ageing/afaf035","DOIUrl":"https://doi.org/10.1093/ageing/afaf035","url":null,"abstract":"Background Inpatient hospitalisation is associated with adverse outcomes in older adults, including hospital-associated deconditioning. The hospital-at-home (HaH) model may promote physical activity. This systematic review and meta-analysis compares functional outcomes between inpatient and HaH settings and evaluates the efficacy of exercise interventions in both settings. Methods Systematic searches of PubMed, Scopus, Web of Science and ScienceDirect were conducted on 27 April 2024. Three distinct searches were performed: (i) studies comparing HaH and inpatient hospitalisation, (ii) trials evaluating inpatient exercise interventions and (iii) research on HaH exercise interventions. Two reviewers independently selected studies published from 2014 onwards using the PICOS framework and they assessed quality using PEDro scale. A meta-analysis was performed using a random effects model to analyse exercise interventions. This systematic review with meta-analysis was conducted according to PRISMA 2020 guidelines and was registered on PROSPERO (CRD42024598286). Results Among the 9470 studies identified, nine studies comparing acute-care settings and 21 studies on exercise interventions (one in HaH) were included. Findings suggest that HaH may positively affect functional and cognitive outcomes. Inpatient exercise interventions significantly improved physical performance [standardised mean difference (SMD) = 0.42, 95% confidence interval (CI) = 0.12–0.72] and functional independence (SMD = 0.45, 95% CI = 0.14–0.77) at discharge. Conclusion HaH may contribute to preserving physical and cognitive status. Supervised exercise interventions during inpatient hospitalisation are safe and effective for improving older adults’ functional status, although further research in the HaH model is needed.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"19 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143462813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}