Age and ageing最新文献_第7页

Association of body age and multiorgan ages with cognitive decline in older adults: a nationwide longitudinal study. 老年人身体年龄和多器官年龄与认知能力下降的关系：一项全国性的纵向研究。

IF 6 2区医学

Age and ageing Pub Date : 2025-05-03 DOI: 10.1093/ageing/afaf132

Maiwulamujiang Maimaitiyiming, Yun Yang, Xueyao Jia, Xinyu Zhang

{"title":"Association of body age and multiorgan ages with cognitive decline in older adults: a nationwide longitudinal study.","authors":"Maiwulamujiang Maimaitiyiming, Yun Yang, Xueyao Jia, Xinyu Zhang","doi":"10.1093/ageing/afaf132","DOIUrl":"https://doi.org/10.1093/ageing/afaf132","url":null,"abstract":"Background: It is unknown whether the relationship between ageing of different organs and cognitive decline varies in older adults.Objectives: This study investigated the association of body ageing and organ-specific ageing with cognitive decline, and whether this relationship was strengthened by hearing loss.Methods: The study included older adults free from cognitive impairment, drawn from the Chinese Longitudinal Healthy Longevity Survey. Organ-specific ages were estimated using the support vector machines. The age gap and ageing rate were calculated. Cognitive function was assessed at each visit using the Mini-mental State Examination, and a linear mixed-effects model was employed for analysis.Results: Over a median follow-up period of 6 years, of 1003 older adults (mean age 80.8 ± 10.9 years, 47.7% female) included, 187 (18.6%) experienced cognitive impairment. Compared to individuals with biological younger for body, musculoskeletal system and immune system, biological older (age gap > 0) was associated with faster cognitive decline (βbody = -0.229, 95% confidence interval [CI]: -0.435, -0.023; βmuscle = -0.294, 95% CI: -0.500, -0.088; βimmune = -0.246, 95% CI: -0.452, -0.041), but not for cardiometabolic and renal systems. A linear positive dose-response association between age gap and cognitive impairment was uniquely observed for musculoskeletal system, whereas null associations for other organ systems. Moreover, higher ageing rates of body and musculoskeletal system were associated with faster cognitive decline. In the joint exposure analysis, hearing loss significantly strengthened the body age gap/ageing rate-cognitive decline association.Conclusions: Advanced biological ageing of the body, musculoskeletal system and immune system, particularly in the presence of hearing loss, accelerates cognitive decline.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"54 5","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mobile phone use characteristics, genetic predisposition and the risk of Parkinson's disease: a prospective cohort study. 手机使用特征、遗传易感性和帕金森病风险：一项前瞻性队列研究

IF 6 2区医学

Age and ageing Pub Date : 2025-05-03 DOI: 10.1093/ageing/afaf143

Juanjuan Zhang, Junjie Zou, Yuerong He, Jiale Shen, Kunjuan Jing, Ruiqi An, Zhen Wang, Xiaoyan Yao, Chao Ren, Yang Xia

引用次数: 0

Frailty and prehospital emergency care: implications for paramedic education. 虚弱和院前急救：对护理人员教育的启示。

IF 6 2区医学

Age and ageing Pub Date : 2025-05-03 DOI: 10.1093/ageing/afaf126

Jan-Niklas Krohn, Katrin Singler

引用次数: 0

The iatrogenic consequences of lower levels of meaningful activity in Geriatric Evaluation and Management inpatients. 老年评估与管理住院患者低水平有意义活动的医源性后果。

IF 6 2区医学

Age and ageing Pub Date : 2025-05-03 DOI: 10.1093/ageing/afaf135

Brian Dolan

引用次数: 0

Prevalence and severity of frailty amongst middle-aged and older adults conveyed to hospital by ambulance between 2010 and 2017 in Wales. 2010年至2017年期间威尔士由救护车送往医院的中老年人中虚弱的患病率和严重程度。

IF 6 2区医学

Age and ageing Pub Date : 2025-05-03 DOI: 10.1093/ageing/afaf124

Carole Fogg, Tracey England, Helen Daniels, Bronagh Walsh

{"title":"Prevalence and severity of frailty amongst middle-aged and older adults conveyed to hospital by ambulance between 2010 and 2017 in Wales.","authors":"Carole Fogg, Tracey England, Helen Daniels, Bronagh Walsh","doi":"10.1093/ageing/afaf124","DOIUrl":"10.1093/ageing/afaf124","url":null,"abstract":"Background: Ambulance services are commonly used by older adults. The scope of services continues to adapt in response to more non-life-threatening calls, often due to the acute consequences of chronic illness. Frailty increases with increasing age, but it is not known how common or severe it is within patients conveyed to hospital by ambulance.Methods: Open cohort of people aged ≥50 living in Wales between 2010 and 2017. Routinely collected electronic data on ambulance attendances resulting in conveyance were linked to primary care data within the Secure Anonymised Information Linkage databank, and the electronic Frailty Index was calculated. The prevalence and severity of frailty according to patient and incident characteristics was described.Results: Of 1 264 094 individuals within the cohort, 23.8% were taken to hospital between 2010 and 2017, of which frailty was present in 84.3% of patients. There was an upward trend in the number of conveyances for patients with moderate and severe frailty across the years in all age groups. The distribution of frailty was similar across call categories, deprivation quintiles and out-of-hours incidents. Patients conveyed from residential homes had a higher level of frailty and comprised 8.7% of the total conveyances.Conclusions: The high prevalence of frailty within adults aged ≥50 with emergency conveyances suggests upskilling ambulance crews with frailty training to enhance their assessment and decision making may improve patient outcomes. The high proportion of conveyances from residential homes indicates scope for increasing integration of community services to provide more patient-centred care pathways.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"54 5","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

75 Years after Marjorie Warren, the 'know-do' gap around hospital-associated functional decline is as wide as ever. 在马乔里·沃伦（Marjorie Warren）去世75年后，围绕与医院相关的功能衰退，“知道”和“知道”的差距依然很大。

IF 6 2区医学

Age and ageing Pub Date : 2025-05-03 DOI: 10.1093/ageing/afaf134

Nicolás Martínez-Velilla, Adam Lee Gordon

引用次数: 0

Effects of reminiscence therapy for loneliness in older adults: a systematic review and meta-analysis. 回忆疗法对老年人孤独感的影响：一项系统回顾和荟萃分析。

IF 6 2区医学

Age and ageing Pub Date : 2025-05-03 DOI: 10.1093/ageing/afaf136

Haiqi Yang, Qiqing Zhong, Bingyue Han, Yuhang Pu, Rendong He, Kexin Huang, Yongliang Jiao, Rui Han, Qinghuan Kong, Yong Jia, Li Chen

{"title":"Effects of reminiscence therapy for loneliness in older adults: a systematic review and meta-analysis.","authors":"Haiqi Yang, Qiqing Zhong, Bingyue Han, Yuhang Pu, Rendong He, Kexin Huang, Yongliang Jiao, Rui Han, Qinghuan Kong, Yong Jia, Li Chen","doi":"10.1093/ageing/afaf136","DOIUrl":"10.1093/ageing/afaf136","url":null,"abstract":"Background: Loneliness has detrimental effects on the mental well-being of senior citizens. Reminiscence therapies have emerged as a potential intervention to alleviate loneliness. This study aimed to systematically review and quantitatively analyse the effects of reminiscence therapy on loneliness among older adults.Methods: A comprehensive search was performed across 11 electronic databases, meta-analyses were used to explore the effectiveness of reminiscence therapy on loneliness among older adults, while multiple subgroup analyses were conducted to explore differences in the effectiveness of different types of reminiscence therapy. This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses.Results: Twenty-two studies were included in the systematic review meta-analysis. The meta-analysis indicated that reminiscence therapy significantly reduced loneliness in older adults (standard mean difference = -1.52, 95% CI [-2.11, -0.93], P < .01). Subgroup analyses showed significant effects for both simple reminiscence and life review therapy. Group reminiscence therapy was more effective than individual reminiscence therapy, and that reminiscence therapy conducted by professional facilitators was more effective than that led by non-professionals.Conclusions: Reminiscence therapy is an effective intervention for reducing loneliness among older adults, highlighting its importance in clinical practice. Future research should explore the best practices for different types of reminiscence therapies, tailored to the personal needs and backgrounds of older adults.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"54 5","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editor's view-electronic frailty index 2: the sequel. 编辑的观点-电子弱点指数2：续集。

IF 6 2区医学

Age and ageing Pub Date : 2025-05-03 DOI: 10.1093/ageing/afaf127

Roy L Soiza

引用次数: 0

The use and effect of virtual reality as a non-pharmacological intervention for behavioural and psychological symptoms of dementia: a systematic review and meta-analysis. 虚拟现实作为痴呆行为和心理症状的非药物干预的使用和效果：系统回顾和荟萃分析

IF 6 2区医学

Age and ageing Pub Date : 2025-05-03 DOI: 10.1093/ageing/afaf117

Li-Chin Wang, Amy Montgomery, Peter Smerdely, Olivia Paulik, Cherie Barton, Elizabeth Halcomb, Heidi Hoi Ying Hui, Carolyn Pieri, Maria Rios Lopez, Judeil Teus, Gemma McErlean

{"title":"The use and effect of virtual reality as a non-pharmacological intervention for behavioural and psychological symptoms of dementia: a systematic review and meta-analysis.","authors":"Li-Chin Wang, Amy Montgomery, Peter Smerdely, Olivia Paulik, Cherie Barton, Elizabeth Halcomb, Heidi Hoi Ying Hui, Carolyn Pieri, Maria Rios Lopez, Judeil Teus, Gemma McErlean","doi":"10.1093/ageing/afaf117","DOIUrl":"10.1093/ageing/afaf117","url":null,"abstract":"Background: Behavioural and psychological symptoms of dementia (BPSD) are complex neuropsychiatric symptoms that contribute to caregiver strain, increased rates of institutionalisation and reduced quality of life. Virtual reality (VR) has gained interest as a non-pharmacological approach to potentially reduce BPSD severity.Objective: This review sought to synthesise evidence on the effectiveness of VR in reducing BPSD severity, while exploring its acceptability, safety, and optimal dosage in dementia care.Methods: MEDLINE, EMBASE, CINAHL and SCOPUS were searched for randomised and quasi-experimental trials assessing VR's effect on BPSD. JBI critical appraisal checklists were used to assess methodological quality. Findings were presented narratively, with meta-analysis performed on a subset of BPSD symptoms where data were available.Results: Of the ten included studies, four found no significant change in overall BPSD. Mixed findings were observed for individual BPSD symptoms. Meta-analysis showed a significant reduction in depressive symptoms (mean diff -0.38, P= .026) and no reduction in agitation (mean diff 1.87, P = .2). Two studies reported reduced aggression and mixed findings were found for anxiety. Reduced apathy was observed in one study following each VR session and during the session in another. VR was generally well-accepted with few side effects reported.Conclusion: VR appears to be an acceptable non-pharmacological intervention for BPSD reduction. However, the limited available studies, methodological variations and quality issues suggest the need for future larger-scale research to confirm its efficacy and effectiveness.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"54 5","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resident funding and care home quality: a retrospective observational analysis of the impact of the two-tier care system in England. 居民资金和护理院质量：英国双层护理系统影响的回顾性观察分析。

IF 6.7 2区医学

Age and ageing Pub Date : 2025-05-03 DOI: 10.1093/ageing/afaf100

Anders Bach-Mortensen,Benjamin Goodair,Michelle Degli Esposti,Christine Corlet Walker

{"title":"Resident funding and care home quality: a retrospective observational analysis of the impact of the two-tier care system in England.","authors":"Anders Bach-Mortensen,Benjamin Goodair,Michelle Degli Esposti,Christine Corlet Walker","doi":"10.1093/ageing/afaf100","DOIUrl":"https://doi.org/10.1093/ageing/afaf100","url":null,"abstract":"BACKGROUNDAdult social care in England operates in a two-tier system of self-funded and state-funded residents. It is unclear, however, whether resident funding source impacts care home quality.METHODSWe conducted a nationwide retrospective observational analysis of care homes in England (n = 28 239 Provider Information Return entries for 14 444 care homes, representing ~367 653 residents), 2021-23, to examine the relationship between resident funding (self- or state-funded) and care home quality (inspection ratings by the industry regulator). We linked data from the Care Quality Commission's Provider Information Return to inspection ratings, area deprivation, and care home and resident characteristics. We modelled a series of logistic regressions, incorporating interaction terms to investigate the interrelationships between ownership (for-profit, third sector, public) and area deprivation.FINDINGSCare homes with more self-funded residents were more likely to have better inspection ratings [odds ratio for each percentage of self-funded residents: 1.01, 95% confidence interval (CI) 1.008-1.012, P < .001]. The effect of self-funded residents on care quality was largest amongst for-profit homes and not statistically significant for third sector and public homes. For homes without self-funders, third sector and public providers were 14.0 (95% CI: 10.1-17.8, P < .001) and 6.9 (95% CI: 4.1-9.7, P < .001) percentage points more likely to be rated higher than for-profit homes.CONCLUSIONSThe quality of for-profit care homes is strongly influenced by the proportion of self-funded residents, whilst third and public sector homes provide consistent care regardless of resident funding source. This strongly impacts care equity for residents nationwide, as the concentration of self-funders is largely determined by area wealth.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"23 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143921094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0