Age and ageing最新文献

{"title":"Conducting adult social care research in the UK—impacts of challenges to study processes on study feasibility","authors":"Joanne M Fitzpatrick, Peter Worsley, Christopher Chatterton, Mandy Fader, Tanya Graham, Christine Norton, Sue Woodward, Ruth Harris","doi":"10.1093/ageing/afaf202","DOIUrl":"https://doi.org/10.1093/ageing/afaf202","url":null,"abstract":"The challenges of conducting adult social care research in the UK have long been documented. Calls have been made repeatedly for greater financial investment in social care research, an aligned research infrastructure including the recruitment of study sites and participants, support for a research culture and enabling capacity for the sector to participate in research. Ultimately these strategies should support researchers to investigate important practice issues that are identified and developed in collaboration with social care, aiming to continue to enhance well-being and quality of life for adults with health and care needs. Our commentary is referenced to a feasibility cluster randomised trial to address the high prevalence of incontinence and the prevention and treatment of incontinence-associated dermatitis for adults living at home who are receiving homecare services and for adults living in long-term care facilities. This study commenced in 2020 and completed in 2025, a 2-year delay because of challenges and protractions, despite innovative solutions throughout the research study, which we share in this commentary. We conclude that despite its unequivocal importance, conducting adult social care research and particularly using trial methodologies in the UK warrant further changes. These should be systemic and happen at pace.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"60 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145246941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of major depression in partners of people with Alzheimer’s disease: a national cohort study","authors":"Casey Crump, Jingkai Wei, Barbara G Vickrey, Alexis C Edwards, Paul E Schulz, Weiva Sieh, Jan Sundquist, Kristina Sundquist","doi":"10.1093/ageing/afaf283","DOIUrl":"https://doi.org/10.1093/ageing/afaf283","url":null,"abstract":"Background Alzheimer’s disease (AD) may cause significant psychosocial distress not only in the patient but also their partner. However, long-term risks of major depression in partners of AD patients are largely unknown. Methods A national cohort study was conducted of all 145 289 partners of people diagnosed with all-cause dementia, including 57 113 partners of people diagnosed with AD, in Sweden during 1998–2017, and 1 300 561 population-based controls. Cox regression was used to compute hazard ratios (HRs) for subsequent risk of major depression identified from nationwide outpatient and inpatient diagnoses through 2018, adjusting for sociodemographic factors and prior mental disorders. Results The 10-year cumulative incidence of major depression was 5.4% in partners of people with AD, 5.6% in partners of people with all-cause dementia, and 3.9% in controls. The adjusted relative rate of major depression was increased ~1.5-fold in partners of people with AD (HR, 1.53; 95% CI, 1.35–1.72) or all-cause dementia (1.45; 1.34–1.57), compared with controls. These risks were elevated among both women (AD: HR, 1.41; 95% CI, 1.22–1.64; all-cause dementia: 1.36; 1.24–1.50) and men (AD: 1.81; 1.46–2.25; all-cause dementia: 1.73; 1.48–2.01). Risks remained significantly elevated ≥3 years later in both women (1.3- to 1.5-fold) and men (1.5-fold). Risks were generally highest in partners aged ≥85 years. Conclusions In this large national cohort, partners of people diagnosed with AD or all-cause dementia had ~1.5-fold risks of major depression, which remained elevated several years later. Partners of people with dementia need psychosocial support and long-term follow-up for timely detection and treatment of depression.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"11 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145241866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cost-consequence analysis of a nudge intervention to improve hospital care of older people at the end of life: results from a stepped-wedge cluster randomised trial","authors":"Hannah E Carter, Thomasina Donovan, Nicole M White, Xing J Lee, Christine Brown, Nicholas Graves, Steven McPhail, Magnolia Cardona, Ben P White, Lindy Willmott, Gillian Harvey, Leonie Callaway, Ken Hillman, Adrian G Barnett","doi":"10.1093/ageing/afaf280","DOIUrl":"https://doi.org/10.1093/ageing/afaf280","url":null,"abstract":"Objectives The ‘Intervention for Appropriate Care and Treatment’ (InterACT) was a nudge intervention to identify hospital patients at risk of imminent death or deterioration and communicate this information to treating clinical teams. The aim was to improve the quality of care delivered. This paper reports a cost-consequence analysis of the InterACT intervention. Methods A stepped-wedge cluster randomised trial was conducted across three large tertiary hospitals in Australia between May 2020 and June 2021. The cost of implementing the intervention was determined using prospectively collected staff time sheets, study documentation and field notes. Changes to hospital admission costs and health service outcomes between the trial’s intervention and control phases are also reported. Hospital admissions costs and other health service outcomes were obtained from hospital databases and patient chart reviews. Results The mean intervention cost was $A 72 per at-risk patient admission identified. Additional site-level implementation costs ranged between $21 373 to $34 867 per hospital site, translating to $23 per at-risk admission. The intervention did not reduce the cost of intensive care unit admission, length of stay, medical emergency calls or in-hospital deaths. Wide confidence intervals around at-risk admission cost differences (95% CI: –$2264 to $3312) indicated there was large uncertainty. Conclusions This cost-consequence analysis found that the intervention was not effective in reducing the cost of non-beneficial treatment, which is consistent with the broader InterACT results. This simple nudge-intervention alone may not be sufficient to impact health service resource use and costs in the complex end-of-life setting.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"123 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of a multi-component hospital avoidance programme in residential aged care homes: a stepped-wedge cluster randomised trial","authors":"Nicole M White, Xing J Lee, Michelle J Allen, Nicholas Graves, Gillian Harvey, Carla Shield, Trudy Dwyer, Claudia Meyer, Florin I Oprescu, Elizabeth V Cyarto, Jeffrey Rowland, Hannah E Carter","doi":"10.1093/ageing/afaf275","DOIUrl":"https://doi.org/10.1093/ageing/afaf275","url":null,"abstract":"Objectives To investigate if a multi-component hospital avoidance intervention would reduce hospital bed days in residential aged care (RAC) homes. Design Prospective stepped-wedge cluster randomised trial with usual care and intervention phases. Setting Eleven RAC homes in Queensland, Australia. Participants The intervention targeted all nursing staff and personal care workers within the participating RAC homes. Outcome data were collected for all residents living in the participating RAC homes at any time throughout the trial period. Intervention The intervention comprised four core components: face-to-face training sessions with all nursing staff and personal care workers; provision of diagnostic medical equipment; decision support tools and embedded implementation facilitation and support. Main outcome measures The primary outcome was the number of hospital bed days per 100 resident days in RAC homes. Secondary outcomes assessed emergency department (ED) transfers, subsequent admissions to hospital and hospital length of stay. Results No statistically significant intervention effects were observed across the reported outcomes. Exposure to the early detection of deterioration in elderly residents intervention was associated with a 27% relative increase in the primary outcome of hospital bed days (Estimate, 95% CI: 1.13, 0.93–1.74, P-value = 0.137). There was an 8% reduction in ED transfers (Estimate, 0.92: 0.74–1.14, P-value = 0.462) and a 10% increase in hospital admissions (Estimate, 1.10, 95% CI: 0.84–1.44, P-value = 0.486). For residents admitted to the hospital, the expected length of stay increased from 4.2 to 4.4 days (Estimate: 1.04; 95% CI: 1.00–1.07; P-value = 0.055). Conclusions Whilst not statistically significant, findings indicate that the intervention was associated with fewer ED transfers, but increased hospital admissions and overall hospital bed days. Programme implementation was impacted by major contextual barriers, notably the COVID-19 pandemic, which contributed to pressures on staffing and workload. Trial registration Australia New Zealand Clinical Trial Registry, ACTRN12620000507987 (registered 23rd April 2020).","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"21 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How air pollution relates to chronic pain in middle-aged and older adults: a Nationwide cohort study","authors":"Hongji Zeng, Rui Wang, Jingbao Zhang, Weijia Zhao, Siyu Luo, Qingmei Wang, Xi Zeng","doi":"10.1093/ageing/afaf291","DOIUrl":"https://doi.org/10.1093/ageing/afaf291","url":null,"abstract":"Objectives This study aimed to investigate the longitudinal associations between chronic pain and NO2, O3, PM1, PM2.5 and PM10 amongst middle-aged and older Chinese adults. Methods This cohort study included 10 616 Chinese participants aged≥45 years. The participants were followed up in five waves between 2011 and 2020. Chronic pain and the affected sites were identified using questionnaires. Participants and air pollution data were matched based on geographic location. Data were obtained from the China Health and Retirement Longitudinal Study and China High Air Pollutants datasets. After adjustment for confounders, time-varying Cox models were used to explore the pain-pollutant association. The linear relationships between air pollutants and general pain risk were tested using exposure-response analysis. Subgroup analyses were conducted based on the affected body sites. Multi-pollutant models were used to explore potential interactions between pollutants. Results Every 10 μg/m3 increase in NO2 (HR = 1.116, 95% CI: 1.051 to 1.186), PM1 (HR = 1.185, 95% CI: 1.112 to 1.265), PM2.5 (HR =1.122, 95% CI: 1.080 to 1.165), and PM10 (HR = 1.089, 95% CI: 1.062 to 1.117) corresponded to a 11.6%, 18.5%, 12.2%, 8.9% higher risk of chronic pain, respectively. O3 significantly increased the risk of chronic headache (HR = 1.018, 95%CI: 1.022 to 1.221). Abdominal and chest pain was only associated with PM2.5. PM pollutants suppressed the effects of NO2, whereas O3 did not influence the effects of other pollutants. Conclusions There were linear associations between multiple air pollutants and the risk of chronic pain. This study emphasised the importance of improving air quality for healthy ageing.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"84 6 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practical strategies for improving medication management during care transitions for older adults with dementia: findings from a novel stakeholder-informed review process","authors":"Cecilia Yachuan Cai, Sylvan Greyson, Maningbe Keita Fakeye, Rhea Sharma, Sara Keller, Ayse P Gurses, Dawn Hohl, Kimberly Carl, Quincy Miles Samus, Alicia Ines Arbaje","doi":"10.1093/ageing/afaf277","DOIUrl":"https://doi.org/10.1093/ageing/afaf277","url":null,"abstract":"Background and Objectives Medication management (MM) can be challenging for older adults with dementia experiencing hospital-to-home-health (HH) transitions. Role ambiguity—lack of clarity regarding who should complete MM tasks—can lead to adverse events. We used a novel stakeholder-informed redesign process (Intervention Refinement Teams; IRTs) to ask family caregivers and HH professionals to: (i) identify MM facilitators and barriers related to role ambiguity during hospital-to-HH transitions, and (ii) develop and prioritize strategies for improvement. Research Design and Methods We conducted three IRT meetings comprised of family caregivers, HH staff and researchers to: (i) detail contributing factors to role ambiguity, (ii) brainstorm strategies to reduce role ambiguity and support MM, and (iii) prioritize strategies by effectiveness, feasibility, sustainability and importance. Results IRT members (n = 14) developed 31 strategies. Top strategies were: (i) establish health system workflows for collection of accurate information to ensure timely home visits, (ii) store home medications securely to decrease risk of adverse events, (iii) notify primary care providers after hospital discharge to ensure timely follow-up, (iv) use cognitive aids for medication storage and administration to reduce risk of errors, and (v) provide dementia-specific training to HH staff. Discussion and Implications Family caregivers and HH professionals identified strategies focused on addressing pandemic- and dementia-specific challenges, MM tasks, clarification of role ambiguity, and care transition quality measurement and feedback. These strategies have potential to improve older adult/caregiver experience during transitions and guide improvement efforts for HH agencies serving recently hospitalized older adults with dementia.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"19 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social inequalities in the use of formal and informal home care in older women: evidence from a large UK cohort study.","authors":"Matthew Quinn,Sasha Shepperd,Sarah Floud","doi":"10.1093/ageing/afaf279","DOIUrl":"https://doi.org/10.1093/ageing/afaf279","url":null,"abstract":"BACKGROUNDAt a time when access to publicly funded social care is constrained relative to need, older people with care needs with the least resources may disproportionately rely on informal care.METHODSIn 2020-21, 66,604 participants from the UK Million Women Study were invited to complete an online survey, which included questions on pre-pandemic receipt of home care. Responses were combined with data collected at recruitment in 1998, a 2010 re-survey, and hospital admissions in 2017-19. We used multivariable logistic regression to assess the association between education level and area deprivation quintile with formal or informal care use, with adjustment for pre-disposing characteristics (age), enabling resources (household composition and size) and care need (including self-rated health and co-morbidities).RESULTSA total of 44,523 women completed the survey; 43,756 were eligible for analysis (mean age 75.6). A total of 1407 (3.2%) received informal care, 544 received formal care (1.2%) and 255 (0.6%) received both. Compared to those with university degrees, those with no qualifications were more likely to receive informal care (OR: 1.50, 95% CI: 1.23-1.84) and less likely to receive formal care (OR: 0.39, 95% CI: 0.25-0.60). The most deprived were more likely to receive informal care (OR: 1.34, 95% CI: 1.09-1.65) compared to the least deprived, and there was a trend across quintiles (Ptrend = .02).CONCLUSIONThis is the largest UK study to assess variation in social care use by education and deprivation. We found inequities in care that may disadvantage older women in deprived areas and with lower levels of education, and their informal carers.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"88 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal changes in the extended networks of depressive symptoms and cognitive functions following bereavement: comparison between progressively depressed and continuously non-depressed older adults","authors":"Daiyan Zhang, Maria Semkovska","doi":"10.1093/ageing/afaf278","DOIUrl":"https://doi.org/10.1093/ageing/afaf278","url":null,"abstract":"Background Late-life depression and cognitive decline share a reciprocal relationship, but the impact of other contributing risk factors, such as bereavement, on this relationship remains unexplored. Temporal network modelling helps infer potential causal relationships between specific risk factors and depression onset. Objectives To compare the extended temporal networks of depressive symptoms and cognitive functions between older adults who developed depression after recent bereavement and those who remained resilient. Methods Unrelated adults over 70 were selected from the Longitudinal Study of Aging in Danish Twins based on three criteria: no prior diagnosis of depression, recent bereavement and complete data on depressive symptoms and cognitive function at two timepoints, set 2 years apart. At follow-up, 1770 remained non-depressed, while 222 developed depression. Cross-lagged panel network (CLPN) analyses were used to examine changes in 15 depressive symptoms and five cognitive functions over time. Results CLPN analyses revealed few temporal predictions between depressive symptoms and cognitive functions in the ‘resilient’ network. In contrast, the ‘depression-onset’ network displayed complex longitudinal interactions. While only one follow-up cognitive function (verbal fluency) was predicted by baseline depressive symptoms, all studied baseline cognitive functions (e.g. memory, attention) predicted variations in symptoms at follow-up, particularly thoughts of worthlessness, life not worth living and anhedonia. The ‘resilient’ group showed significant change in network structure over time, whereas ‘depression-onset’ group did not. Conclusions Following bereavement, resilient older adults showed a flexible extended network of depressive symptoms and cognitive functions. Lower baseline cognitive function within a structurally unchanging network appeared to trigger depression-onset.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"4 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex- and system-specific analysis of blood-based biomarkers and frailty in older adults—the Activity and Function of the Elderly study","authors":"Felix Joachim Boehm, Lea Fritzenschaft, Stefanie Braig, Michael Denkinger, Dietrich Rothenbacher, Dhayana Dallmeier","doi":"10.1093/ageing/afaf255","DOIUrl":"https://doi.org/10.1093/ageing/afaf255","url":null,"abstract":"Background Underlying pathophysiological mechanisms behind frailty are not fully understood. Objective To evaluate the sex- and system-specific association of 35 blood-based biomarkers with frailty. Method Baseline data from the population-based Activity and Function of the Elderly study (≥65 years), collected between March 2009 and April 2010, was used. Frailty was defined through a frailty index (FI). Biomarkers associations with frailty were analysed sex-, and organ−/system-specific. Frailty models were built using backwards selection in Generalized Linear Models (GLM) for continuous and logistic regression (LR) for dichotomized FI (FI ≥0·2 frail), adjusting for age, education, smoking and alcohol intake, with further adjustment for medications when needed. Residual mean squared error (RMSE), area under the curve (AUC), sensitivity, specificity, positive and negative predictive value (PPV, NPV) were estimated. Results Among 1180 participants (57·9% men) GLMs showed a good fit of the data with gamma-glutamyl transferase, high-density lipoprotein–, low-density lipoprotein–cholesterol and growth differentiation factor 15 overall, and sex-specific transferrin, alanine transaminase, testosterone, vitamin D, lactate dehydrogenase, NT-proBNP in men (RMSE 0·064, specificity 0·96, NPV 0·86), and leucocytes, cystatin C, DHEA, fT3, hs-cTnT in women (RSME 0·074, specificity 0·94, NPV 0·87). LR models included less biomarkers with similar properties (AUC 0·83, specificity 0·80, 0·93 NPV in men; AUC 0·85, specificity 0·72, NPV 0·94 in women). Conclusion Obtained models provide insight into sex-specific differences related to frailty. Surprisingly, inflammation does not play an important role when taking all other biomarkers into account. Obtained models offer a good framework for the identification of blood-based biomarkers to be used in frailty prediction models.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"13 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145133602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seven candidate interventions to address abuse of older people","authors":"Laura Campo-Tena, Jeffrey H Herbst, Wan Y Choo, David Burnes, Mélanie Couture, Fatemeh Estebsari, Christelle S L Kafando, George Rouamba, Marie-Madeleine Simbreni, Elsie Yan, Yongjie Yon, Christopher Mikton","doi":"10.1093/ageing/afaf248","DOIUrl":"https://doi.org/10.1093/ageing/afaf248","url":null,"abstract":"The Abuse of Older People – Intervention Accelerator (AOP-IA) project aims to accelerate the development of effective interventions to prevent and reduce AOP aged 60 and older within the framework of the United Nations Decade of Healthy Ageing (2021–2030). The AOP-IA was launched in response to the global need for interventions with proven effectiveness, as few existing approaches have been rigorously evaluated. This paper focuses on the first two phases of the AOP-IA project, which involved conducting a systematic search, screening and evaluation process to identify candidate interventions ready to be rigorously evaluated in future stages of the project, as well as establishing a network of intervention developers. The identification of interventions included an initial screening of 13 926 records and two rounds of evaluations by an expert panel. From this process, 89 promising interventions were identified, and subsequently, seven candidate interventions were selected for more rigorous scientific testing and evaluation. An adapted version of the Systematic Screening and Assessment Method was used to identify these interventions. The AOP-IA project demonstrates that interventions to prevent and reduce abuse of older adults exist in a variety of settings and countries, and that several interventions are ready for a rigorous evaluation to support continual programme improvement by intervention developers and long-term sustainability and scale-up globally.","PeriodicalId":7682,"journal":{"name":"Age and ageing","volume":"55 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}