American journal of public health最新文献_第5页

Minimum Legal Age of Nonmedical Cannabis Purchase Laws and Cannabis-Related Hospitalizations in Canada, 2015 to 2022. 2015年至2022年加拿大非医用大麻购买法律和大麻相关住院的最低法定年龄。

IF 12.7 1区医学

American journal of public health Pub Date : 2025-05-22 DOI: 10.2105/ajph.2025.308090

Daniel T Myran,Robert Talarico,Rosalie Liccardo Pacula,Jennifer Xiao,Doug Manuel,Erin Hobin,Lauren Konikoff,Peter Tanuseputro,Monica Taljaard

{"title":"Minimum Legal Age of Nonmedical Cannabis Purchase Laws and Cannabis-Related Hospitalizations in Canada, 2015 to 2022.","authors":"Daniel T Myran,Robert Talarico,Rosalie Liccardo Pacula,Jennifer Xiao,Doug Manuel,Erin Hobin,Lauren Konikoff,Peter Tanuseputro,Monica Taljaard","doi":"10.2105/ajph.2025.308090","DOIUrl":"https://doi.org/10.2105/ajph.2025.308090","url":null,"abstract":"Objectives. To determine whether the minimum legal age (MLA) for cannabis purchases is associated with reductions in cannabis-related hospitalizations in youths. Methods. We performed a population-based study examining all hospitalizations for cannabis use in Canada for individuals aged 15 to 44 years (n = 14.6 million in 2018) between January 1, 2015, and March 31, 2022. MLAs varied across Canada. We used a controlled interrupted time series design to compare changes in cannabis-related hospitalizations between individuals above and below the MLA. Results. There were 137 901 cannabis-related hospitalizations during the study. Prelegalization rates of hospitalizations were increasing by 2% per quarter for individuals above and below the MLA. After legalization, hospitalizations began declining by 2% per quarter in individuals below the MLA (rate ratio [RR] quarterly slope change = 0.96; 95% confidence interval [CI] = 0.95, 0.98) with no slope change for individuals above the MLA. The total effect, 3.5 years after legalization, was a 34% reduction (relative difference = 0.66; 95% CI = 0.49, 0.91; P = .011) in hospitalizations for those below relative to those above the MLA. Conclusions. Nonmedical cannabis legalization in Canada was associated with reductions in cannabis-related hospitalizations for youths below the MLA and with ongoing increases for individuals above the MLA. Public Health Implications. The results suggest that cannabis legalization may increase cannabis-related hospitalizations in adults but that MLAs may prevent such increases for at-risk young people in regions pursuing cannabis legalization. (Am J Public Health. Published online ahead of print May 22, 2025:e1-e9. https://doi.org/10.2105/AJPH.2025.308090).","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"35 1","pages":"e1-e9"},"PeriodicalIF":12.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Flexible Framework for Urgent Public Health Climate Action. 紧急公共卫生气候行动的灵活框架。

IF 12.7 1区医学

American journal of public health Pub Date : 2025-05-22 DOI: 10.2105/ajph.2025.308061

Heather A Joseph,Stephenie C Lemon,Karin Valentine Goins,Semra A Aytur,Sara Zimmerman,Edward Alexander,Claudia Brown,Shubhayu Saha,Paul J Schramm

{"title":"A Flexible Framework for Urgent Public Health Climate Action.","authors":"Heather A Joseph,Stephenie C Lemon,Karin Valentine Goins,Semra A Aytur,Sara Zimmerman,Edward Alexander,Claudia Brown,Shubhayu Saha,Paul J Schramm","doi":"10.2105/ajph.2025.308061","DOIUrl":"https://doi.org/10.2105/ajph.2025.308061","url":null,"abstract":"Climate change poses profound threats to human safety, health, and well-being. Public health agencies, especially state, territorial, local, and Tribal health departments, can play an essential role in climate change adaptation and mitigation. Public health climate action can protect health, promote health equity, and increase climate change resilience. The Centers for Disease Control and Prevention has updated its original climate and health framework for practitioners and expanded its utility by developing practical guidance. The revised framework, Building Resilience Against Climate Effects, supports health departments and their partners by providing an accessible approach that can be tailored to different contexts. The framework has been updated to center justice, equity, and belonging; integrate climate change mitigation or reduction of greenhouse gas emissions that cause climate change; and address agency capacity. The Building Resilience Against Climate Effects framework also emphasizes collaboration, especially cross-sectoral and community partnerships, communication, and evaluation. Framework elements, key tactics, and guiding principles are presented in a pragmatic, step-by-step implementation guide. The implementation guide can be used by state, territorial, local, and Tribal health departments to galvanize or expand their engagement with public health climate action, which grows more urgent each year. (Am J Public Health. Published online ahead of print May 22, 2025:e1-e12. https://doi.org/10.2105/AJPH.2025.308061).","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"20 1","pages":"e1-e12"},"PeriodicalIF":12.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Access to Paid Sick Leave and COVID-19 Vaccination Status Among Employed Adults Aged 18-64 Years in the United States, 2021-2022. 2021-2022年美国18-64岁就业成年人的带薪病假和COVID-19疫苗接种状况

IF 12.7 1区医学

American journal of public health Pub Date : 2025-05-22 DOI: 10.2105/ajph.2025.308095

Eric W Lundstrom,Abay Asfaw,Rebecca Tsai

{"title":"Access to Paid Sick Leave and COVID-19 Vaccination Status Among Employed Adults Aged 18-64 Years in the United States, 2021-2022.","authors":"Eric W Lundstrom,Abay Asfaw,Rebecca Tsai","doi":"10.2105/ajph.2025.308095","DOIUrl":"https://doi.org/10.2105/ajph.2025.308095","url":null,"abstract":"Objectives. To measure the associations between access to paid sick leave (PSL) and COVID-19 vaccination status in the United States, both overall and stratified by occupation and industry of employment. Methods. We extracted data on employed adults aged 18 to 64 years from the 2021 and 2022 US Medical Expenditure Panel Survey. We assessed associations between PSL and COVID-19 vaccination status using logistic regression. We used marginal effects analyses to estimate associations within occupation and industry groups. Results. Our analytic sample (n = 15 089) represented more than 114 million employed US adults. Access to PSL was significantly associated with receipt of a COVID-19 vaccination (adjusted odds ratio = 1.33; 95% confidence interval = 1.14, 1.55). Marginal effects analyses indicated that this association was significant within most occupation and industry groups. Conclusions. These findings suggest PSL is associated with higher COVID-19 vaccination rates among US workers. PSL remains an important tool for improving preventive health care access and reducing rates of infectious disease in the United States. (Am J Public Health. Published online ahead of print May 22, 2025:e1-e4. https://doi.org/10.2105/AJPH.2025.308095).","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"64 1","pages":"e1-e4"},"PeriodicalIF":12.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

State-Level Estimates of Nonfatal Firearm Injury Hospitalizations, 2000-2021. 2000-2021年非致命火器伤害住院的州级估计。

IF 12.7 1区医学

American journal of public health Pub Date : 2025-05-15 DOI: 10.2105/ajph.2025.308069

Rosanna Smart,James Murphy,Terry L Schell,Andrew R Morral,Nancy Nicosia

{"title":"State-Level Estimates of Nonfatal Firearm Injury Hospitalizations, 2000-2021.","authors":"Rosanna Smart,James Murphy,Terry L Schell,Andrew R Morral,Nancy Nicosia","doi":"10.2105/ajph.2025.308069","DOIUrl":"https://doi.org/10.2105/ajph.2025.308069","url":null,"abstract":"Objectives. To create a comprehensive, publicly available data set of state-level nonfatal firearm injury inpatient hospitalizations (NFIIHs) in the United States from 2000 to 2021. Methods. We used Bayesian modeling to impute missing NFIIH rates for 334 state-year observations and correct for incomplete injury mechanism coding in 766 observations. Results. NFIIH rates increased nationally, with the largest rise between 2019 and 2020, up by one third to reach 1.31 (95% credibility interval [CrI] = 1.27, 1.35) per 10 000 population. State prevalences ranged from 0.18 (95% CrI = 0.14, 0.22) in Hawaii to 2.18 (2.04, 2.33) in Louisiana. South Central states (Mississippi, Arkansas, Missouri) had the largest increases. Twelve states-predominantly in the Northeast and West-experienced decreases. NFIIH rates correlated more strongly with firearm homicide rates (correlation = 0.86) than other intents (correlations < 0.28). Nationwide, there were 2.4 NFIIHs for every firearm homicide, but this ratio varied more than fourfold across states. Conclusions. NFIIH rates varied substantially across and within states. Despite strong correlation, many states diverged from the national NFIIH to firearm homicide ratio. Public Health Implications. Firearm deaths systematically underrepresent serious firearm injuries in some states. This new data set can inform how policies affect serious firearm injuries and injury lethality. (Am J Public Health. Published online ahead of print May 15, 2025:e1-e9. https://doi.org/10.2105/AJPH.2025.308069).","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"128 1","pages":"e1-e9"},"PeriodicalIF":12.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

World Trade Center (WTC) Exposures and Cardiometabolic Risk Among WTC Health Program General Responders. 世贸中心（WTC）健康计划一般应答者的暴露和心脏代谢风险。

IF 12.7 1区医学

American journal of public health Pub Date : 2025-05-15 DOI: 10.2105/ajph.2025.308079

Helena Krasnov,Krupa Ambalal Patel,Pablo Knobel,Hsiao-Hsien Leon Hsu,Susan L Teitelbaum,Mary Ann McLaughlin,Allan C Just,Maayan Yitshak Sade

{"title":"World Trade Center (WTC) Exposures and Cardiometabolic Risk Among WTC Health Program General Responders.","authors":"Helena Krasnov,Krupa Ambalal Patel,Pablo Knobel,Hsiao-Hsien Leon Hsu,Susan L Teitelbaum,Mary Ann McLaughlin,Allan C Just,Maayan Yitshak Sade","doi":"10.2105/ajph.2025.308079","DOIUrl":"https://doi.org/10.2105/ajph.2025.308079","url":null,"abstract":"Objectives. To assess the association between World Trade Center (WTC) exposures, cardiometabolic diseases (CMDs), and trajectories of glucose and systolic blood pressure (SBP) among WTC Health Program general responders (WTHPGR). Methods. We included monitoring visits (2003-2021) of WTHPGR who participated in the operations in New York City after the September 11, 2001, attack (n = 47 795). The WTC Health Program assessed WTC exposures using questionnaires and measured trajectories during monitoring study visits; CMDs were self-reported. We assessed associations with CMDs (hazard ratios and their corresponding 95% confidence intervals [CIs]) using survival analyses. We assessed associations with trajectories (odds ratios and their corresponding 95% CIs) using logistic regressions. Results. Interquartile range (IQR) increases in the number of days on-site in the 9 months following the attack were associated with increased diabetes (1.057; 95% CI = 1.025, 1.089) and hypertension (1.035; 95% CI = 1.014, 1.057) risks. IQR increases in hours on-site during September 2001 were associated with worsening glucose (1.040; 95% CI = 1.017, 1.064) and SBP (1.006; 95% CI = 1.001, 1.010) trajectories. Conclusions. WTC exposures are associated with higher CMD risk and worsening cardiometabolic trajectories among WTHPGR. Public Health implications. Linking WTC exposures to emerging diseases is vital because of its impact on health care costs and treatment access among WTHPGR. (Am J Public Health. Published online ahead of print May 15, 2025:e1-e9. https://doi.org/10.2105/AJPH.2025.308079).","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"8 1","pages":"e1-e9"},"PeriodicalIF":12.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 Vaccine Mandate and Vaccination Rates in the US Military, 2020‒2022. 2020-2022年美国军队COVID-19疫苗授权和疫苗接种率

IF 12.7 1区医学

American journal of public health Pub Date : 2025-05-15 DOI: 10.2105/ajph.2025.308120

Elizabeth J Dullea,Angelia A Eick-Cost,Cara H Olsen,James D Mancuso

{"title":"COVID-19 Vaccine Mandate and Vaccination Rates in the US Military, 2020‒2022.","authors":"Elizabeth J Dullea,Angelia A Eick-Cost,Cara H Olsen,James D Mancuso","doi":"10.2105/ajph.2025.308120","DOIUrl":"https://doi.org/10.2105/ajph.2025.308120","url":null,"abstract":"Objectives. To assess the effect of the vaccination mandate on COVID-19 vaccination rates and identify independent factors associated with lack of postmandate vaccination among service members. Methods. We assessed all active component service members for COVID-19 vaccination status from December 11, 2020, to January 1, 2022. We used comparative interrupted time series analysis and logistic regression to compare pre- and postmandate completion of the vaccine series between the US military and the US general population. Results. Previous documented infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), lower rank, and non-Hispanic Black race were associated with lower premandate vaccination. Postmandate vaccination rates were significantly higher in the active component population (P < .001) compared with the premandate period and the US population. Also notable was the higher incidence of postmandate vaccination among those who were non-Hispanic Black or of lower rank. Conclusions. The US military's COVID-19 vaccination mandate was effective at both increasing overall vaccination rates and reducing disparities in vaccination, including race and ethnicity and rank. Vaccine mandates increase the receipt of vaccines and promote health, readiness, and equity within the US military. (Am J Public Health. Published online ahead of print May 15, 2025:e1-e11. https://doi.org/10.2105/AJPH.2025.308120).","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"53 1","pages":"e1-e11"},"PeriodicalIF":12.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Decarceral Response to HIV Criminalization in the Black LGBTQIA+ Community. 黑人LGBTQIA+社区艾滋病定罪的宣言回应。

IF 12.7 1区医学

American journal of public health Pub Date : 2025-05-15 DOI: 10.2105/ajph.2025.308110

Louis Listerud,Steven Meanley,Alana Richards,Blake Kosciow,Stephen Bonett

{"title":"A Decarceral Response to HIV Criminalization in the Black LGBTQIA+ Community.","authors":"Louis Listerud,Steven Meanley,Alana Richards,Blake Kosciow,Stephen Bonett","doi":"10.2105/ajph.2025.308110","DOIUrl":"https://doi.org/10.2105/ajph.2025.308110","url":null,"abstract":"HIV criminalization statutes continue to disproportionately impact Black queer and trans individuals, particularly Black transgender and gender-expansive people and sex workers, and have historically served as a way to inequitably punish communities for a disease that affects them because of inequitable systems rooted in the legacy of slavery. To achieve the Centers for Disease Control and Prevention's 2030 goals for Ending the HIV Epidemic in the US, it is essential to take bold steps to decriminalize HIV and interrogate the role of criminalization in reinforcing stigma, exacerbating the social determinants of health, and further disenfranchising marginalized communities. Through the analysis of the theory of racial capitalism, we aim to make the argument for complete decriminalization of HIV as a small step in the ultimate goal of prison abolition and decarceration of all peoples. We advocate rejecting efforts aiming to modernize statutes that further concretize the punitive role prisons play in a capitalist society and systematically revoke HIV-affected communities' right to freedom. Multilevel policies must address the racialized nature of HIV criminalization. (Am J Public Health. Published online ahead of print May 15, 2025:e1-e9. https://doi.org/10.2105/AJPH.2025.308110).","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"42 1","pages":"e1-e9"},"PeriodicalIF":12.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Was the Allocation of COVID-19 Vaccines Globally Fair and Equitable? COVID-19疫苗的全球分配是否公平公正？

IF 12.7 1区医学

American journal of public health Pub Date : 2025-05-15 DOI: 10.2105/ajph.2025.308077

Ezekiel J Emanuel,Min Jung

{"title":"Was the Allocation of COVID-19 Vaccines Globally Fair and Equitable?","authors":"Ezekiel J Emanuel,Min Jung","doi":"10.2105/ajph.2025.308077","DOIUrl":"https://doi.org/10.2105/ajph.2025.308077","url":null,"abstract":"Determining whether an allocation is equitable requires ethical and empirical analyses, specifically answers to 3 questions: (1) What is the ethical standard for fair allocation? (2) What is the quantitative equity metric for this standard? and (3) What do the empirical data demonstrate? Two ethical standards for assessing the fair allocation of scarce medical resources have been delineated: the COVID-19 Vaccines Global Access initiative's population-based standard and the COVID-19 health-burden standard. The equity metric for the population-based standard is vaccine per person in each country, and for the health-burden standard it is vaccine per excess deaths per country. When using excess deaths data from the World Health Organization and vaccine data from the United Nations Children's Fund, the health-burden standard showed that middle-income countries with high excess deaths (e.g., Indonesia, Peru, Mexico, Egypt, South Africa) were treated inequitably: not provided enough vaccines given their high excess deaths. The right standard to assess fair and equitable allocation is a health-burden assessment. According to this standard, contrary to assumptions and initial claims, low-income countries were not treated inequitably in COVID-19 vaccine allocation, and middle-income countries with high excess deaths were treated inequitably. (Am J Public Health. Published online ahead of print May 15, 2025:e1-e10. https://doi.org/10.2105/AJPH.2025.308077).","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"3 1","pages":"e1-e10"},"PeriodicalIF":12.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adverse Childhood Experiences Among LGBTQ+ High School Students: National Evidence From the 2023 Youth Risk Behavior Survey. LGBTQ+高中生的不良童年经历：来自2023年青少年风险行为调查的国家证据

IF 12.7 1区医学

American journal of public health Pub Date : 2025-05-08 DOI: 10.2105/ajph.2025.308094

Joel Mittleman

{"title":"Adverse Childhood Experiences Among LGBTQ+ High School Students: National Evidence From the 2023 Youth Risk Behavior Survey.","authors":"Joel Mittleman","doi":"10.2105/ajph.2025.308094","DOIUrl":"https://doi.org/10.2105/ajph.2025.308094","url":null,"abstract":"Objectives. To provide population-representative estimates of US high school students' exposure to adverse childhood experiences (ACEs), separately by sexual orientation, gender identity, and 3 demographic moderators: sex assigned at birth, race/ethnicity, and age. Methods. Using data from the 2023 US National Youth Risk Behavior Survey (n = 12 131), this cross-sectional study calculated descriptive statistics, estimated multivariable regressions, and screened for mischievous respondents. Results. Lesbian, gay, bisexual, transgender, and questioning (LGBTQ+) students reported elevated exposure to 8 separate ACEs, with a cumulative ACE score of 3.0 (95% confidence interval [CI] = 2.9, 3.1), compared with 1.8 (95% CI = 1.7, 1.9) among cisgender-heterosexual (cishet) students. This pattern held across all demographic subgroups and could not be explained by mischievous responders. Nearly half (46.1%; 95% CI = 39.7, 52.5) of all gender minorities reported 4 or more ACEs, compared with 34.5% (95% CI = 30.9, 38.0) of cisgender sexual minorities and 15.4% (95% CI = 14.2, 16.7) of cishet students. Conclusions. The first national ACE prevalence data for US high school students show that LGBTQ+ youths-particularly transgender youths-face far greater levels of abuse, neglect, and other adversities than cishet youths. (Am J Public Health. Published online ahead of print May 8, 2025:e1-e9. https://doi.org/10.2105/AJPH.2025.308094).","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"48 1","pages":"e1-e9"},"PeriodicalIF":12.7,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sequencing-Based Detection of Measles in Wastewater: Texas, January 2025. 基于测序的废水中麻疹检测：德克萨斯州，2025年1月。

IF 12.7 1区医学

American journal of public health Pub Date : 2025-05-08 DOI: 10.2105/ajph.2025.308146

Sara Javornik Cregeen,Michael J Tisza,Blake Hanson,Marissa Cook,Anil Surathu,Rebecca Schneider,Jingjing Wu,Kirstin Short,Kaavya Domakonda,Loren Hopkins,Matthew C Ross,Joseph F Petrosino,Jennifer Deegan,Lauren B Stadler,Eric Boerwinkle,Anthony Maresso

{"title":"Sequencing-Based Detection of Measles in Wastewater: Texas, January 2025.","authors":"Sara Javornik Cregeen,Michael J Tisza,Blake Hanson,Marissa Cook,Anil Surathu,Rebecca Schneider,Jingjing Wu,Kirstin Short,Kaavya Domakonda,Loren Hopkins,Matthew C Ross,Joseph F Petrosino,Jennifer Deegan,Lauren B Stadler,Eric Boerwinkle,Anthony Maresso","doi":"10.2105/ajph.2025.308146","DOIUrl":"https://doi.org/10.2105/ajph.2025.308146","url":null,"abstract":"Measles is a potentially deadly viral infection spread via respiratory droplets from infected individuals. Outbreaks occur when vaccine coverage drops below the threshold of herd, or community, immunity. Using a sequencing-based approach, we report the prospective (January 7, 2025) detection of measles in nucleic acid extracts from 2 wastewater treatment plants in Houston, Texas, with a population of more than 218 000 residents. The sequencing data from 2 samples contained 53 unique reads mapping to 11 different regions of the measles virus genome with a 99.4% match to genotype B3. Importantly, no detections were observed from 821 previous samples from the same city spanning nearly 3 years of monitoring. The findings were confirmed using droplet digital polymerase chain reaction. A concomitant investigation identified 2 unvaccinated measles-positive travelers living within the same sewershed as the wastewater detection event. This work suggests that sequencing-based wastewater analysis is valuable as a comprehensive early detection warning system that facilitates more targeted epidemiological investigation. (Am J Public Health. Published online ahead of print May 8, 2025:e1-e5. https://doi.org/10.2105/AJPH.2025.308146).","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"36 1","pages":"e1-e5"},"PeriodicalIF":12.7,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0