{"title":"Addressing Transgender Erasure in HIV Clinical Trials: The Scorecard for Transgender and Gender-Diverse Inclusion.","authors":"Brian Minalga,Cindra Feuer","doi":"10.2105/ajph.2025.308134","DOIUrl":"https://doi.org/10.2105/ajph.2025.308134","url":null,"abstract":"We sought to offer a structured framework for evaluating transgender and gender-diverse (TGD) inclusion in HIV clinical trials, with actionable criteria for trial design and conduct, and to quantify and characterize TGD inclusion in pivotal HIV studies as supporting evidence of the need for this framework. We devised a tool (scorecard) consisting of 14 scoreable indicators for TGD-responsive HIV research with input from global TGD communities. We tested the scorecard in a cross-sectional review of 41 randomized controlled HIV biomedical efficacy trials to measure TGD responsiveness. Studies were selected to represent the spectrum of groundbreaking HIV therapeutic and prevention studies enrolling participants in countries around the world from 1991 to 2023. We found that TGD individuals represent a reported 2532 (1.4%) of 178 893 participants in the selected HIV clinical trials. Scorecard indicators reveal a dearth of HIV research responsive to the needs of TGD communities. The lack of TGD representation in HIV clinical trials indicates a historical erasure of TGD communities with potential public health consequences. The scorecard might guide future HIV research to be more responsive to the needs of TGD people. (Am J Public Health. Published online ahead of print August 7, 2025:e1-e10. https://doi.org/10.2105/AJPH.2025.308134).","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"16 1","pages":"e1-e10"},"PeriodicalIF":12.7,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gender Affirmation Research Is Not Gender Ideology Extremism, It Is Science.","authors":"Arjee J Restar,Kristi E Gamarel,Don Operario","doi":"10.2105/ajph.2025.308220","DOIUrl":"https://doi.org/10.2105/ajph.2025.308220","url":null,"abstract":"","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"17 1","pages":"e1-e5"},"PeriodicalIF":12.7,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adam M Whalen,Alexander Furuya,Jessica Contreras,John A Schneider,Sahnah Lim,Chau Trinh-Shevrin,Asa Radix,Dustin T Duncan
{"title":"Discrimination and Sleep Health Among Transgender Women of Color in New York City: Cross-Sectional and Longitudinal Associations From the TURNNT Cohort Study.","authors":"Adam M Whalen,Alexander Furuya,Jessica Contreras,John A Schneider,Sahnah Lim,Chau Trinh-Shevrin,Asa Radix,Dustin T Duncan","doi":"10.2105/ajph.2025.308208","DOIUrl":"https://doi.org/10.2105/ajph.2025.308208","url":null,"abstract":"Objectives. To determine whether discrimination is associated with sleep health among transgender women of color. Methods. We included 269 participants from the Trying to Understand Relationships, Networks, and Neighborhoods Among Transgender Women of Color (TURNNT) Cohort Study in New York City in a cross-sectional analysis and 179 in a longitudinal analysis of the association between discrimination and sleep duration, quality, and latency. Results. Median sleep duration was 6 hours per night, with 65% of participants reporting poor sleep in the past month. Nearly two thirds experienced moderate or high levels of discrimination. Cross sectionally, high discrimination was associated with a 14% greater risk of poor sleep quality relative to low discrimination (prevalence ratio [PR] = 1.14). Longitudinally, high discrimination was associated with a 15% higher risk of poor sleep (PR = 1.15) and an average of 43 minutes less per night. Conclusions. Transgender women of color generally do not receive an adequate amount of sleep, and that sleep is often of poor quality. Those who experience higher rates of discrimination are particularly vulnerable to poor sleep health. Public Health Implications. Effort should be focused on reducing antitransgender discrimination and developing interventions to mitigate the negative impact of discrimination on sleep health among transgender populations. (Am J Public Health. Published online ahead of print August 7, 2025:e1-e10. https://doi.org/10.2105/AJPH.2025.308208).","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"56 1","pages":"e1-e10"},"PeriodicalIF":12.7,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Legal Recognition of Same-Sex Marriage in Asia Is an Opportunity to Improve LGBTQ+ Physical and Mental Health.","authors":"Yiu Tung Suen","doi":"10.2105/AJPH.2025.308102","DOIUrl":"10.2105/AJPH.2025.308102","url":null,"abstract":"","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":" ","pages":"1196-1199"},"PeriodicalIF":9.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12243644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum In: \"Intersectional HIV Stigma Among Black Women: Regional Differences and Implications From the Black Women First Initiative\".","authors":"","doi":"10.2105/AJPH.2025.308037e","DOIUrl":"10.2105/AJPH.2025.308037e","url":null,"abstract":"","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":" ","pages":"1330"},"PeriodicalIF":9.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12243636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily J Johnson, Hunter Pluckebaum, Karin D Martin, Benjamin Danielson, Brenda Majercin, Sheila Ater Capestany, Vivian H Lyons
{"title":"Youth Detention and Incarceration Facilities in the United States (2010 to February 2023): Mapping Closure Intents and Implementation.","authors":"Emily J Johnson, Hunter Pluckebaum, Karin D Martin, Benjamin Danielson, Brenda Majercin, Sheila Ater Capestany, Vivian H Lyons","doi":"10.2105/AJPH.2025.308118","DOIUrl":"10.2105/AJPH.2025.308118","url":null,"abstract":"<p><p><b>Objectives.</b> To characterize youth detention and incarceration facility closure attempts in the United States from January 2010 to February 2023 and inform ongoing attempts for facility closure. <b>Methods.</b> We conducted a landscape analysis of youth facilities with stated intent to close during our study period. For each facility, we coded for jurisdiction (state vs local), year of attempt, stated reasons for closure, outcome of the facility (closed, remained open, or other), facility size, and what happened to youths after the facility closed. <b>Results.</b> We identified a total of 118 facilities in 33 states that had committed to closure in our study period. The most cited reasons for the intention to close were cost (69% of facilities), declining numbers (46%), operational and facilities issues (36%), reform (33%), and conditions of confinement and abuse (30%). Sixty-two percent of identified facilities closed (n = 73). <b>Conclusions.</b> Most facilities that had announced closures did close. For facilities that closed, the most commonly cited reasons were cost and decreasing numbers. Reform as a reason was more common in facilities that remained open than closed. (<i>Am J Public Health</i>. 2025;115(8):1299-1307. https://doi.org/10.2105/AJPH.2025.308118).</p>","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":" ","pages":"1299-1307"},"PeriodicalIF":9.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12243654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144281978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Collecting Data Is Just the First Step: The Importance of Training Providers for Patient Encounters.","authors":"Shine Chang,Miria Kano","doi":"10.2105/ajph.2025.308106","DOIUrl":"https://doi.org/10.2105/ajph.2025.308106","url":null,"abstract":"","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"28 1","pages":"1327-1328"},"PeriodicalIF":12.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144594236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Global LGBTQ+ Public Health in the Face of Legal Persecution.","authors":"Stewart Landers,B Ethan Coston","doi":"10.2105/ajph.2025.308122","DOIUrl":"https://doi.org/10.2105/ajph.2025.308122","url":null,"abstract":"","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":"1 1","pages":"1229-1230"},"PeriodicalIF":12.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144594105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cynthia Tucker, Tamika L Foust, Nicole Baldwin, Tamecia Moore
{"title":"Breaking Barriers: Advancing Employment Opportunities for Black Women.","authors":"Cynthia Tucker, Tamika L Foust, Nicole Baldwin, Tamecia Moore","doi":"10.2105/AJPH.2025.308153","DOIUrl":"10.2105/AJPH.2025.308153","url":null,"abstract":"<p><p>Employment has emerged as a critical focus in HIV interventions for Black women. A multilevel, community-based employment initiative in Chicago, Illinois, focused on justice-involved Black women with HIV. This program addressed complex barriers through bundled interventions, including navigation services and case management, with a major focus on employment. The evaluation demonstrated improvements in employment outcomes and health care access. The initiative's success underscores its potential as a model for addressing the complex intersecting challenges faced by Black women with HIV. (<i>Am J Public Health</i>. 2025;115(8):1226-1228. https://doi.org/10.2105/AJPH.2025.308153).</p>","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":" ","pages":"1226-1228"},"PeriodicalIF":9.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12243661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fanghui Shi, Xueying Yang, Ruilie Cai, Jiajia Zhang, Sayward E Harrison, Shan Qiao, Sarah Grace Frary, Xiaoming Li
{"title":"Identification of Transgender and Gender-Diverse Individuals in the All of Us Research Program, 2017-2022.","authors":"Fanghui Shi, Xueying Yang, Ruilie Cai, Jiajia Zhang, Sayward E Harrison, Shan Qiao, Sarah Grace Frary, Xiaoming Li","doi":"10.2105/AJPH.2025.308129","DOIUrl":"10.2105/AJPH.2025.308129","url":null,"abstract":"<p><p><b>Objectives.</b> To develop computable phenotype algorithms to identify a transgender and gender-diverse (TGD) cohort by using diverse data sources in All of Us, a national community-engaged program to facilitate health equity in the United States by partnering with 1 million participants. <b>Methods.</b> We identified TGD individuals in All of Us by applying inclusion criteria based on conditions, laboratory measurements, or medications related to being TGD in electronic health record data or confirmed survey responses, using participant data collected between May 31, 2017, and July 1, 2022. <b>Results.</b> Of 413 457 participants, we identified 4781 (1.2%) as TGD. Participants aged 18 to 29 years (26.1% vs 8.2%), who were bisexual (20.7% vs 3.5%), with annual income of less than $25 000 (35.9% vs 24.7%), and with housing security concerns (31.9% vs 16.0%) accounted for a larger proportion of TGD individuals than non-TGD individuals. <b>Conclusions.</b> Combining survey and electronic health record data enables the identification of TGD individuals who have been missed by previous studies that used survey data alone in All of Us to explore health disparities in TGD people. (<i>Am J Public Health</i>. 2025;115(8):1278-1287. https://doi.org/10.2105/AJPH.2025.308129).</p>","PeriodicalId":7647,"journal":{"name":"American journal of public health","volume":" ","pages":"1278-1287"},"PeriodicalIF":9.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12243640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}