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An Efficient Fully Automated Method for Gridding Microarray Images 一种高效的全自动化微阵列图像网格化方法
American Journal of Biomedical Engineering Pub Date : 2012-08-31 DOI: 10.5923/J.AJBE.20120203.04
F. Z. M. Labib, I. A. Fouad, M. Mabrouk, A. Sharawy
{"title":"An Efficient Fully Automated Method for Gridding Microarray Images","authors":"F. Z. M. Labib, I. A. Fouad, M. Mabrouk, A. Sharawy","doi":"10.5923/J.AJBE.20120203.04","DOIUrl":"https://doi.org/10.5923/J.AJBE.20120203.04","url":null,"abstract":"DNA microarray is a powerful tool and is widely used in genetics to monitor expression levels of thousands of genes in parallel. The gene expression process consists of three stages: gridding, segmentation and quantification. Grid- ding deals with finding areas in the microarray image which contain one spot using grid lines. This step can be done ma- nually or automatically. In this paper, we propose an efficient and simple automatic gridding method for microarray image analysis. This method was implemented using MATLAB software and found very effective for gridding arrays with low intensity, poor quality spotsand tested by a number of microarray images. Results show that this method gives high accu- racy of 76.9% improved to 98.6% when a preprocessing step is considered, rendering the method a promising technique for an efficient and automatic gridding the noisy microarray images.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"50 1","pages":"115-119"},"PeriodicalIF":0.0,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73076148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Electronic Cough Monitor 电子咳嗽监测仪
American Journal of Biomedical Engineering Pub Date : 2012-08-31 DOI: 10.5923/J.AJBE.20120202.07
Musaab Hassan, A. Satti, A. Hussien, Tarteel Tag El-Din
{"title":"Electronic Cough Monitor","authors":"Musaab Hassan, A. Satti, A. Hussien, Tarteel Tag El-Din","doi":"10.5923/J.AJBE.20120202.07","DOIUrl":"https://doi.org/10.5923/J.AJBE.20120202.07","url":null,"abstract":"Cough is an important symptom to consider when diagnosing diseases. Hence, information about level as well as the rate of cough could be very useful for physicians. In this work, a cough monitoring system was designed. The designed system was capable of recording only cough sounds using appropriate circuit. The circuit utilizes a simple transducer (uni- directional microphone). An LED (light emitting diode) was caused to light every time a cough sound is detected. The design was also accompanied with a programmed alarm (using ATmega8535L) if the number of coughs exceeds certain number.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"202 1","pages":"38-40"},"PeriodicalIF":0.0,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80218069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Handheld Imaging System for Contactless Tri-Modal Biometric Identification 用于非接触式三模态生物识别的手持成像系统
American Journal of Biomedical Engineering Pub Date : 2012-08-31 DOI: 10.5923/J.AJBE.20110102.12
S. Mil'shtein, V. O. Kunnil, C. McPherson, A. Pillai
{"title":"Handheld Imaging System for Contactless Tri-Modal Biometric Identification","authors":"S. Mil'shtein, V. O. Kunnil, C. McPherson, A. Pillai","doi":"10.5923/J.AJBE.20110102.12","DOIUrl":"https://doi.org/10.5923/J.AJBE.20110102.12","url":null,"abstract":"Fingerprinting is the most widely used form of biometric identification because large databases are already available and law enforcement agencies have decades of experience with this technology. In addition, many fingerprinting units on the market are small in size, low power, and inexpensive. Common deficiencies carried by current fingerprinting technologies are distortions introduced when the finger touches the surface of the reader. The current study describes the development of a novel, handheld, contactless fingerprinting system which is capable of acquiring individual fingers with 180 degree view (first modality). Liveliness is examined by transmitted Infra-Red (IR) light (second modality), which allows the viewing of blood vessel networks and \"four-slap\" images and palm prints (third modality). This system is able to produce fingerprint images which are approximately 99% accurate representations of a finger's surface. This was verified by exam- ining a NIST certified aluminum test sample. As demonstrated in our study, this is compared to an average of 15% distortion of the distances between a finger's ridges when imaged with contact based systems. Our radial line-scan imaging allows for \"nail-to-nail\" acquisition of an individual fingerprint, where the format of the recorded image is analogous to an \"ink-rolled\" fingerprint. The system will securely and wirelessly transfers fingerprint images to any law enforcement center via built-in Wi-Fi connection.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"55 1 1","pages":"68-71"},"PeriodicalIF":0.0,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87708553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Design of a Microcontroller Based and X-Ray Waveform Independent kVp-Meter 基于单片机的x射线波形独立kvp计的设计
American Journal of Biomedical Engineering Pub Date : 2012-08-31 DOI: 10.5923/J.AJBE.20110101.07
Y. Ülgen, Murat Tumer
{"title":"Design of a Microcontroller Based and X-Ray Waveform Independent kVp-Meter","authors":"Y. Ülgen, Murat Tumer","doi":"10.5923/J.AJBE.20110101.07","DOIUrl":"https://doi.org/10.5923/J.AJBE.20110101.07","url":null,"abstract":"The kVp setting is one of the major factors affecting the image quality in X-ray imaging and should be an- nually measured and calibrated if necessary. In this work, a kVp-meter is designed around the ATmega16 (Atmel) micro- controller, based on the physical principle that the linear attenuation coefficient of materials, namely copper has a smooth dependence on the energy level of the X- ray photons. Based on the logarithm of the ratio of the radiation intensities through 0.5mm and 1mm thick copper filters, a look-up table is generated in the range 60-120kVp. Logarithmic operation increased the precision at higher kVp values. Since sampling is performed over the exposure period in a continuous manner, the measurement is not affected by the X-ray waveform. A prototype unit was built and the performance was tested in terms of accuracy, precision and reliability.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"82 1","pages":"41-43"},"PeriodicalIF":0.0,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85509569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Analysis of CT Images of Liver for Surgical Planning 肝脏CT图像对手术计划的分析
American Journal of Biomedical Engineering Pub Date : 2012-08-31 DOI: 10.5923/J.AJBE.20120202.05
A. H. Foruzan, Yenwei Chen, R. Zoroofi, M. Kaibori
{"title":"Analysis of CT Images of Liver for Surgical Planning","authors":"A. H. Foruzan, Yenwei Chen, R. Zoroofi, M. Kaibori","doi":"10.5923/J.AJBE.20120202.05","DOIUrl":"https://doi.org/10.5923/J.AJBE.20120202.05","url":null,"abstract":"We developed a Computer Assisted Surgery system which prepared a virtual environment for a physician to interact with the liver and decide on the therapy planning. It was composed of three modules: liver segmentation, vessel extraction, and simulator. We proposed a semi-automatic method to segment the liver. Hepatic veins, portal veins, and he- patic arteries were extracted from multi-phase CT datasets. The simulator visualized the segmented objects and provided for a physician a virtual scalpel to cut the liver. Initially, a transparent view of the liver was shown to the physician that revealed the location of the vascular structures. During the surgery, a toggling option made it possible to switch between a transparent and an opaque view. The width, height, and depth of the cut could be changed by user interaction. The proposed system is a framework which can later be extended to a complete system for analysis of hepatic diseases and therapy planning.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"80 1","pages":"23-28"},"PeriodicalIF":0.0,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72651262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Diazinon Affects the Cytoarchitecture of Seminiferous Epithelium in Rat Testis 二嗪农对大鼠睾丸精系上皮细胞结构的影响
American Journal of Biomedical Engineering Pub Date : 2012-08-31 DOI: 10.5923/J.AJBE.20120202.03
D. Damodar, Urban J A D'Souza, A. Biswas, Shankar Bhat
{"title":"Diazinon Affects the Cytoarchitecture of Seminiferous Epithelium in Rat Testis","authors":"D. Damodar, Urban J A D'Souza, A. Biswas, Shankar Bhat","doi":"10.5923/J.AJBE.20120202.03","DOIUrl":"https://doi.org/10.5923/J.AJBE.20120202.03","url":null,"abstract":"Chemical pollution and reproductive toxicity has a close association leading into a possible infertility. Tes- ticular toxicity induced by chemicals is easy to evaluate since it has a pool of differentiating cells of different stages in the seminiferous epithelium. Most of the pesticide related preclinical studies have heavily dependent upon investigations on sperm density, abnormal sperm percent, reproductive hormone levels etc. Most of the toxins, in addition may affect the seminiferous tubular architecture, harmony as well as supporting cells such as Sertoli cells. Diazinon and its adverse sperm toxic effects are documented earlier but its effects on seminiferous tubules are less recorded. The present study was designed to evaluate the effect of oral administration of diazinon (6mg, 7.5mg and 10mg/kg body weight/day for 5 and 30days) on acetylcholine esterase activity, histological aspects of testes and seminiferous tubular morphometry (STD & SEH). Acetyl- choline esterase activity was significantly decreased as a sign of toxicity, the dose tested. The STD and SEH were signifi- cantly decreased in all the 30days diazinon exposed groups. Histologically testes showed vacuoles, disruption and sloughing of basal germinal epithelium. This study confirms that diazinon disrupts cytoarchitectural components which may interfere with spermatogenesis.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"57 1","pages":"13-16"},"PeriodicalIF":0.0,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83418275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Distance and Location of Both Mobile Phones and Health Care Units: Determines the Interference Level 移动电话和保健单位的距离和位置:决定干扰水平
American Journal of Biomedical Engineering Pub Date : 2012-08-31 DOI: 10.5923/J.AJBE.20110102.14
S. Helhel, Zeynep Colak, S. Ozen
{"title":"Distance and Location of Both Mobile Phones and Health Care Units: Determines the Interference Level","authors":"S. Helhel, Zeynep Colak, S. Ozen","doi":"10.5923/J.AJBE.20110102.14","DOIUrl":"https://doi.org/10.5923/J.AJBE.20110102.14","url":null,"abstract":"Million mobile phone holders in the country forces clinics and cellular phones have been started to be in concern as an electromagnetic interference (EMI) source in hospitals. Hospital buildings are very huge buildings that they are not allowing deep radio penetration through the hole those results in higher uplink power transmission (2W of maxi- mum). These two reasons were our motivation to make an investigation to examine the EMI issues surrounding medical equipment, due to interference from communication devices, including GSM900, GSM1800, and 3G digital mobile phones. Electromagnetic interference, particularly of the ECG and ted EEG device was observed, and exposure begins within the range of 1.25m. It has been observed that uplink power is not a reason of interference itself, but the locations of mobiles and health care units are also the reason of interference.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"6 1","pages":"78-82"},"PeriodicalIF":0.0,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79713386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Biomedical Image Watermarking in Wavelet Domain for Data Integrity Using Bit Majority Algorithm and Multiple Copies of Hidden Information 基于比特多数算法和多拷贝隐藏信息的小波域生物医学图像水印
American Journal of Biomedical Engineering Pub Date : 2012-08-31 DOI: 10.5923/J.AJBE.20120202.06
K. Pal, G. Ghosh, M. Bhattacharya
{"title":"Biomedical Image Watermarking in Wavelet Domain for Data Integrity Using Bit Majority Algorithm and Multiple Copies of Hidden Information","authors":"K. Pal, G. Ghosh, M. Bhattacharya","doi":"10.5923/J.AJBE.20120202.06","DOIUrl":"https://doi.org/10.5923/J.AJBE.20120202.06","url":null,"abstract":"The current paper presents a novel and unique scheme for biomedical image watermarking in wavelet domain by hiding multiple copies of the same data in the cover image using bit replacement in the horizontal (HL) and vertical (LH) resolution approximation image components. The proposed scheme uses an approach for recovering the hidden information from the damaged copies due to unauthorized alteration of the data by applying an algorithm to find the closest twin of the embedded information by bit majority algorithm. Experimental results of the proposed watermarking technique show much enhancement in the visual and statistical invisibility of hidden information after data recovery that supports the improvement in performance.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"30 1","pages":"29-37"},"PeriodicalIF":0.0,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74058667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 30
Left Ventricle Segmentation in Cardiac MRI Images 心脏MRI图像中的左心室分割
American Journal of Biomedical Engineering Pub Date : 2012-08-31 DOI: 10.5923/J.AJBE.20120203.07
Marwa M. A. Hadhoud, M. Eladawy, A. Farag, F. Montevecchi, U. Morbiducci
{"title":"Left Ventricle Segmentation in Cardiac MRI Images","authors":"Marwa M. A. Hadhoud, M. Eladawy, A. Farag, F. Montevecchi, U. Morbiducci","doi":"10.5923/J.AJBE.20120203.07","DOIUrl":"https://doi.org/10.5923/J.AJBE.20120203.07","url":null,"abstract":"Imaging of the left ventricle using cine short-axis MRI sequences, considered as an important tool that used for evaluating cardiac function by calculating different cardiac parameters. The manual segmentation of the left ventricle in all image sequences takes a lot of time, and therefore the automatic segmentation of the left ventricle is main step in cardiac function evaluation. In this paper, we proposed an automatic method for segmenting the left ventricle in cardiac MRI images. We applied pixel classification method by using number of features and KNN classifier for segmenting the left ventricle Cavity, and from its output we can get the endocardial contour. Then, we transformed image pixels from Cartesian to polar coordinates for segmenting the epicardial contour. This method was tested on large number of images, and we achieved good results reached to 95.61% sensitivity, and 98.9% specificity for endocardium segmentation, and 93.32% sensitivity, and 98.49% specificity for epicardium segmentation. The results of the proposed method show the availability for fast and reliable segmentation of the left ventricle.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"45 1","pages":"131-135"},"PeriodicalIF":0.0,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82018725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Enhancement of Infra-Red Images of Human Hand 人眼手的红外图像增强
American Journal of Biomedical Engineering Pub Date : 2012-08-31 DOI: 10.5923/J.AJBE.20110101.10
A. Pillai, S. Mil'shtein
{"title":"Enhancement of Infra-Red Images of Human Hand","authors":"A. Pillai, S. Mil'shtein","doi":"10.5923/J.AJBE.20110101.10","DOIUrl":"https://doi.org/10.5923/J.AJBE.20110101.10","url":null,"abstract":"Among the various technologies used for medical imaging, Infra-Red methods occupies very important place, as IR light interaction with human body became to be a base for thermography, tomography and visualization of blood vessels. Different types of medical imaging techniques exists which are classified on the basis of the wavelength of the radiation used, the mode of operation (transmission or reflection) and the reproduction of the acquired information in the form of images. The human hand is one of the most complicated mechanical -biological objects. The complexity of various bones and tendons, joints and muscles, various soft tissues and network of blood vessels presents a significant challenge to any visualization technique. The request of medical professionals for clarity of hand images requires elimination of some parts of the image, colorizing, and contrast enhancement. In this study, we report significant improvement of IR images of the hand. Enhanced IR images allow clear visualization of tendons which are otherwise seen only by MRI.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"129 1","pages":"59-61"},"PeriodicalIF":0.0,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89307064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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