M. El-Nawawy, Lubna Koraitim, O. Abouelatta, Hanan Hegazi
{"title":"Depth of Cure and Microhardness of Nanofilled, Packable and Hybrid Dental Composite Resins","authors":"M. El-Nawawy, Lubna Koraitim, O. Abouelatta, Hanan Hegazi","doi":"10.5923/J.AJBE.20120206.03","DOIUrl":"https://doi.org/10.5923/J.AJBE.20120206.03","url":null,"abstract":"Resin-based composites are used worldwide in dentistry as they are used in a huge variety of clinical applications, as an esthetic restorative material with excellent physical and mechanical properties when adequate polymerization is obtained. In this study, depth of cure and microhardness of three composites were measured and compared. A total of sixty hu man mandibular first molars were used. The teeth were d ivided into three main groups (20 teeth each) according to the co mposite resins that were used. In group I, Surefil (packab le co mposite) was used as the restorative material. In group II, Esthet-X-improved (nanofilled co mposite) was used, while in group III Glacier (hybrid co mposite) was used. Each group was subdivided into four subgroups (five teeth each) according to the storage intervals (24 hours, one week, two weeks, and three weeks). In each group, occlusomesial cavities were prepared with diamond burs and restored with the composite, according to manufacturer's instructions. In all specimens, composite was applied to the cavity using incremental technique. All the restored teeth were subjected to in v itro thermal cycling and mechanical loading simulat ing a total o f six months in vivo function. Depth of cure was evaluated using penetrometer and microhardness was measured using Vicker's microhardness tester. A significant difference in depth of cure and microhardness were found between the three composites used. Depth of cure and microhardness of the packable composite was better than the other two composites used. There was a fairly good correlation between the microhardness and the depth of cure for the three co mposite materials.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"18 1","pages":"241-250"},"PeriodicalIF":0.0,"publicationDate":"2013-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90447732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biomedical Magnesium Alloys: A review of material properties, surface modifications and potential as a biodegradable orthopaedic implant","authors":"G. Poinern, S. Brundavanam, D. Fawcett","doi":"10.5923/J.AJBE.20120206.02","DOIUrl":"https://doi.org/10.5923/J.AJBE.20120206.02","url":null,"abstract":"Magnesium and magnesium based alloys are lightweight metallic materials that are extremely biocompatible and have similar mechanical properties to natural bone. These materials have the potential to function as an osteoconductive and biodegradable substitute in load bearing applications in the field of hard tissue engineering. However, the effects of corrosion and degradation in the physiological environment of the body has prevented their wide spread application to date. The aim of this review is to examine the properties, chemical stability, degradation in situ and methods of improving the corrosion resistance of magnesium and its alloys for potential application in the orthopaedic field. To be an effective implant, the surface and sub-surface properties of the material needs to be carefully selected so that the degradation kinetics of the implant can be efficiently controlled. Several surface modification techniques are presented and their effectiveness in reducing the corrosion rate and methods of controlling the degradation period are discussed. Ideally, balancing the gradual loss of material and mechanical strength during degradation, with the increasing strength and stability of the newly forming bone tissue is the ultimate goal. If this goal can be achieved, then orthopaedic implants manufactured from magnesium based alloys have the potential to deliver successful clinical outcomes without the need for revision surgery.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"78 1","pages":"218-240"},"PeriodicalIF":0.0,"publicationDate":"2013-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74160719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Poinern, X. Le, Marion E Hager, T. Becker, D. Fawcett
{"title":"Electrochemical synthesis, characterisation, and preliminary biological evaluation of an anodic aluminium oxide membrane with a pore size of 100 nanometres for a Potential Cell Culture Substrate","authors":"G. Poinern, X. Le, Marion E Hager, T. Becker, D. Fawcett","doi":"10.5923/J.AJBE.20130306.01","DOIUrl":"https://doi.org/10.5923/J.AJBE.20130306.01","url":null,"abstract":"In this study we investigate the electrochemical synthesis and characterisation of a nanometre scale porous anodic aluminium oxide (AAO) membranes with a mean pore diameter of 100 nm. The membranes exhibit interesting properties such as controllable pore diameters, periodicity and density distribution. These properties can be preselected by adjusting the controlling parameters of a temperature controlled two-step anodization process. The surface features of the nanometre scale membrane such as pore density, pore diameter and inter-pore distance were quantified using field emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM). A preliminary biological evaluation of the membranes was carried out to determine cell adhesion and morphology using the Cercopithecus aethiops[African green monkey – (Vero)] kidney epithelial cell line. Optical microscopy, FESEM and AFM investigations revealed the presence of focal adhesion sites over the surface of the porous membranes. The positive outcomes of the study, indicates that AAO membranes can be used as a viable tissue scaffold for potential tissue engineering applications in the future.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"43 1","pages":"119-131"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82336184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Guiomar, L. Ribeiro, A. Ribeiro, A. Abrantes, J. Pinheiro, Rui Almeida, Kevin Azevedo
{"title":"Image Quality Assessment of Head CT: Control Charts as an Useful Instrument","authors":"J. Guiomar, L. Ribeiro, A. Ribeiro, A. Abrantes, J. Pinheiro, Rui Almeida, Kevin Azevedo","doi":"10.5923/S.AJBE.101310.01","DOIUrl":"https://doi.org/10.5923/S.AJBE.101310.01","url":null,"abstract":"Themain objective of this research was to determine if the diagnostic image, acquired by CT scan, meets the quality criteria previously established for head CT exams. A total of 360 Head Co mputed Tomography exams were analy zed, using a checklist. For data collect ion, quality criteria were created, organized into four criteria groups, consisting of multip le items that must appear in the images studies. After data processing, a large number o f non-conformexaminations were identified in than more than 50% of the sample. We concluded the main causes of these results are: the \"incorrect or incomp lete positioning\", the \"lack of name of the radiographer and \"mot ion artefacts\". Therefore it is essential to implement a checklist for a systematic evaluationof procedures.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"37 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81127342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Image Quality Control in Digital Radiology. American Journal of Biomedical Engineering","authors":"A. Abrantes","doi":"10.5923/S.AJBE.101310.02","DOIUrl":"https://doi.org/10.5923/S.AJBE.101310.02","url":null,"abstract":"","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91372158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Marocolo, A. Maior, P. Katayama, G. Mota, O. Neto, Andrezza Lauria, E. Santos
{"title":"Anabolic steroid treatment induces cardiac autonomic dysfunction in rats: time-course of heart rate variability","authors":"M. Marocolo, A. Maior, P. Katayama, G. Mota, O. Neto, Andrezza Lauria, E. Santos","doi":"10.5923/J.AJBE.20130303.02","DOIUrl":"https://doi.org/10.5923/J.AJBE.20130303.02","url":null,"abstract":"The aim of this study was to investigate time-course of cardiac autonomic activity in rats treated with nandrolonedecanoate (DECA). Twenty male Wistar rats received weekly 10 mg.Kg-1 of DECA (DG) or vehicle (CG) during 8 weeks. To heart rate variability analysis SDNN (standard deviation of RR intervals), RMSSD (square root of the mean squared differences of successive RR intervals), pNN5 (percentage of successive RR interval differences greater than 5ms) and Poincare analysis was applied in time-domain. Additionally, power spectral was decomposed into high (HF: 0.8-2.5Hz) and low-frequency (LF: 0.2-0.85Hz). For the HF component, differences were found between DG and CG during 4th, 6th and 8th weeks. Progressive increase in the LF-HF ratio was found in DG, resulting in significant differences between groups in 4th, 6th, 7th and 8th weeks. DG showed decreased from 24.5±7.2ms2 to 3.9±2.55ms2 in HF corresponding (83.9% of alteration). Power spectral density function for HF corresponded to 26.3±8.3% and 26.5±4.1% in the 1st and 8th weeks (P=NS) for CG, whereas the DG showed reduced significantly from 26.4±3.6% (1st) to 18.99±2.7% (8th week). Cardiac autonomic dysfunction may constitute an early consequence of DECA administration and an important marker of arrhythmia vulnerability and sudden death identification.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"48 1","pages":"54-62"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89976182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Towards Implementation of Ethical Principles: Privacy and Confidentiality in Medical Data Mining—Indian Scenario","authors":"A. U M, Anandakumar. K. R","doi":"10.5923/J.AJBE.20120205.02","DOIUrl":"https://doi.org/10.5923/J.AJBE.20120205.02","url":null,"abstract":"Datasets constitute a fundamental part of any medical research. Medical data sets (ie, medical records) are generally noted to be large, comp lex, heterogeneous, hierarchical, t ime related, and of varying quality. Such frag mented and distributed data sets challenge efficient data integration and interpretation. Application of data min ing techniques for healthcare related data will be h ighly rewarding. Lack of do main knowledge within healthcare providers calls for active collaboration between the doctor and data miner. Ethical concerns, especially issues of consent and confidentiality have resulted in the introduction of stringent regulations in doing this form o f research in Ind ia. However we found that only 16% of the reviewed publications in medical data mining within India reported of having undergone ethical rev iew. This suggests that the ethical considerations while p racticing data mining is very much undermined. It is mandatory to obtain ethical and legal clearance fro m reg ional as well as Institutional Ethics Rev iew Board (IERB), before using data min ing tools in health care research.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"27 1","pages":"202-205"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89257152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Segmentation Approach to Extract Human Mandible Bones Based on Actual Computed Tomography Data","authors":"T. M. Nassef","doi":"10.5923/J.AJBE.20120205.01","DOIUrl":"https://doi.org/10.5923/J.AJBE.20120205.01","url":null,"abstract":"In this paper, a new approach for segmenting different anato mical regions in dental Com puted Tomography (CT) studies is presented. The approach consists of three st eps: Hounsfield unit's threshold (HU) based on gray -level segmentation, multi-object with texture extraction and anatomical regions identification. First, a HU threshold window sets to separate between different regions upon their gray-level values; second, a set of objects are generated by and texture descriptors are calculated for selected windows from the image data sample. Finally, identification of different anatomical regions set for mandible bones cortical and cancellous. It is expected that the proposed approach will also help automate different semi-automatic segm entation techniques by providing initial boundary points for deformable models or seed points for split and merge segmentation algorithms. Preliminary results obtained for dental CT studies of human-mandible are presented.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"40 1","pages":"197-201"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80541020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Preliminary Investigation into the Design of an Implantable Optical Blood Glucose Sensor","authors":"A. Trabelsi, M. Boukadoum, M. Siaj","doi":"10.5923/J.AJBE.20110102.11","DOIUrl":"https://doi.org/10.5923/J.AJBE.20110102.11","url":null,"abstract":"A preliminary investigation into the design of a near-infrared (NIR) optical bio-implant for accurate meas- urement of blood glucose level is reported. The use of an array of electrically pumped vertical-cavity surface-emitting laser (VCSEL) diodes at specific wavelengths for high-power narrow single-frequency emission leads to a high signal-to-noise ratio in the measured NIR absorption spectrum while maximizing the sensor's sensitivity to small absorption changes. The emission wavelengths lie within the combination and first-overtone spectral bands known to be dominated by glucose absorption information. A Quantum well infrared (QWI) photodiode transducer senses the received optical power after passing through the blood sample, followed by an artificial neural network (ANN) for the measurement of glucose in a whole blood matrix. For an independent test set made with fresh bovine blood, the optimal ANN topology for processing the two selected spectral bands yielded a standard error of prediction of 0.42 mM (i.e., 7.56 mg/dl) over the glucose level range of 4−20 mM. The empirical results obtained with a prototype mounted on PCB for blood glucose monitoring are closely correlated with the absorption spectra collected on a Vertex 70 Bruker spectrometer.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"34 1","pages":"62-67"},"PeriodicalIF":0.0,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73118626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detection and Quantification of Coronary Atherosclerotic Plaque Using Different Imaging Modalities","authors":"M. K. Moridani","doi":"10.5923/J.AJBE.20120202.01","DOIUrl":"https://doi.org/10.5923/J.AJBE.20120202.01","url":null,"abstract":"The behavior and composition of coronary atherosclerotic plaques are ultimately responsible for the threat of acute ischemic events in patients with coronary artery disease. Different imaging modalities have been developed over the last several years in order to better characterize the atherosclerotic plaque and attempt to predict those in peril of com- plication. Recent advances in imaging modalities, including invasive and non-invasive studies, have allowed us to examine the histological components that comprise these plaques. Specific information such as variations in temperature, plaque stiffness and calcification level is currently being researched as well as biological and chemical markers. Since vulnerable plaques cannot be identified by stress testing or angiography, new modalities such as intravascular ultrasound, intracoronary thermography, intravascular palpography, optical coherence tomography, intravascular radia- tion detection, magnetic resonance imaging, radionucleotide imaging, and spectroscopy are under investigation. In this paper we consider to analyze and compare the Atherosclerotic Plaque detection methods.","PeriodicalId":7620,"journal":{"name":"American Journal of Biomedical Engineering","volume":"72 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73367460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}