发布求助
文献互助 智能选刊 最新文献

Materia medica Polona. Polish journal of medicine and pharmacy最新文献

筛选
英文 中文
A comparative study of: long-term alpha-1-blocker, Doxazosin therapy versus surgery in the treatment of benign prostatic hyperplasia. 长期α -1阻滞剂Doxazosin治疗与手术治疗良性前列腺增生的比较研究。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-10-01
S Dutkiewicz
{"title":"A comparative study of: long-term alpha-1-blocker, Doxazosin therapy versus surgery in the treatment of benign prostatic hyperplasia.","authors":"S Dutkiewicz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Results of surgically treated BPH patients 6 mo. after surgery (Group I) were compared with those obtained in patients treated with Doxazosin for 3 yrs. (Group II). Surgery provided better improvement in uroflowmetry parameters, residual volume values and obstructive symptom scores (complete relief). Nevertheless, urinary flow rates normalized upon Doxazosin therapy. Higher prostate specific antigen (PSA) levels in Group II may be explained by the greater size of the adenoma. Postoperative adverse events were reported by some patients in contrast with those treated with Doxazosin. Doxazosin, due to its symptomatic and uroflowmetric efficacy, favourable safety profile and simple dosing schedule has a place in the management of symptomatic BPH patients.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 4","pages":"151-2"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19962466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Warsaw Poison Control Centre, member of the World Network. 华沙毒物控制中心，世界网络成员。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-10-01
J Szajewski
{"title":"The Warsaw Poison Control Centre, member of the World Network.","authors":"J Szajewski","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 4","pages":"137-40"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19961192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative pharmacokinetics and bioavailability of flavonoid glycosides of Ginkgo biloba after a single oral administration of three formulations to healthy volunteers. 健康志愿者单次口服三种制剂后银杏黄酮苷的比较药代动力学和生物利用度。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-10-01
J Wójcicki, B Gawrońska-Szklarz, W Bieganowski, M Patalan, H K Smulski, L Samochowiec, J Zakrzewski
{"title":"Comparative pharmacokinetics and bioavailability of flavonoid glycosides of Ginkgo biloba after a single oral administration of three formulations to healthy volunteers.","authors":"J Wójcicki,&nbsp;B Gawrońska-Szklarz,&nbsp;W Bieganowski,&nbsp;M Patalan,&nbsp;H K Smulski,&nbsp;L Samochowiec,&nbsp;J Zakrzewski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Eighteen healthy volunteers received three different formulations of Ginkgo biloba: capsules (A) and drops (B) (delivered by Agon Pharma), and tablets (C) (Tebonin-Dr. W. Schwabe) in equal an quantity, orally as a single dose, at an interval of at least five days. The pharmacokinetic parameters of the most important flavonoid glycosides: quercetin, kaempferol and isorhamnetin were established. The bioavailability was estimated using capsules as a standard formulation. Only the time to reach the peak concentration (tmax) of quercetin, kaempforol and isorhamnetin administered in the form of capsules, was significantly prolonged as compared with drops and tablets. Area under the curve (AUC) was the largest for formulation B for all the evaluated flavonoid glycosides, however the differences were not statistically significant. It is concluded that the three formulations of Ginkgo biloba extract are bioequivalent.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 4","pages":"141-6"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19962465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A questionnaire for the assessment of quality of life in cancer patients in Turkey. 土耳其癌症患者生活质量评估问卷。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-10-01
O Ozyilkan, E Karaagaoglu, A Topeli, A Kars, E Baltali, G Tekuzman, D Firat
{"title":"A questionnaire for the assessment of quality of life in cancer patients in Turkey.","authors":"O Ozyilkan,&nbsp;E Karaagaoglu,&nbsp;A Topeli,&nbsp;A Kars,&nbsp;E Baltali,&nbsp;G Tekuzman,&nbsp;D Firat","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this study, we developed a reliable scale to measure the quality of life (QOL), which would reflect the cultural characteristics of cancer patients in Turkey. We used the Rolls-Royce model and determined a form with 49 items in eight dimensions such as general well-being, physical symptoms and activity, sleep dysfunctions, appetite, sexual dysfunction, cognitive functions, medical interaction, social participation and work performance. The forms were used for assembling data from 100 subjects (10 physicians, 19 healthy volunteers, 18 patients relatives, 28 patients on chemotherapy, 25 patients off chemotherapy). Half-split reliability and the signal effect were used to demonstrate reliability and responsiveness. After demonstrating the validity of the test, the final form was constructed. When these eight dimensions were factor analysed, it was found that the general well-being and sexual dysfunction were the most important determinants of QOL.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 4","pages":"153-6"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19962468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The acetylation and oxidation phenotypes in insulin-dependent diabetes mellitus. 胰岛素依赖型糖尿病的乙酰化和氧化表型。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-10-01
A Mrozikiewicz, D Kiełczewska-Mrozikiewicz, Z Lowicki, E Chmara, P M Mrozikiewicz, A Jabłecka, E Kaźmierczak, I Andrys
{"title":"The acetylation and oxidation phenotypes in insulin-dependent diabetes mellitus.","authors":"A Mrozikiewicz,&nbsp;D Kiełczewska-Mrozikiewicz,&nbsp;Z Lowicki,&nbsp;E Chmara,&nbsp;P M Mrozikiewicz,&nbsp;A Jabłecka,&nbsp;E Kaźmierczak,&nbsp;I Andrys","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Polymorphism of the acetylation and oxidation phenotypes in patients with IDDM was evaluated. A greater statistically significant number of fast acetylators in IDDM was found.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 4","pages":"147-9"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19962467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Haptoglobin in rheumatic fever. 风湿热中的触珠蛋白。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-07-01
K Anil, K Praveen, Sadhna, P K Gupta
{"title":"Haptoglobin in rheumatic fever.","authors":"K Anil,&nbsp;K Praveen,&nbsp;Sadhna,&nbsp;P K Gupta","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum haptoglobin levels were studied in rheumatic fever and in established rheumatic heart disease to find whether rheumatic activity influenced serum haptoglobin levels. The study was carried out on 90 subjects of paediatric age group, comprising 30 children suffering from acute rheumatic fever (Group I) and Group II of 30 children of established rheumatic heart disease (not having rheumatic activity). They were matched with group III of 30 normal children of the same age as controls. Levels of ASO titre, C-reactive protein, serum haptoglobin and ESR were estimated in all cases of study and control groups. Estimations of serum haptoglobin levels and ESR were repeated in all children of rheumatic fever after 2 weeks. Haptoglobin levels were estimated by electrophoresis on a cellulose acetate paper. In healthy children (Group III) mean serum haptoglobin was 92.2 +/- 19.77 mg%. This was significantly lower when compared with acute rheumatic fever group before treatment (606.58 +/- 171.04 mg%) and rheumatic heart disease group (120.8 +/- 26.03 mg%).</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 3","pages":"108-10"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19898761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The clinical course of untreated asymptomatic bacteriuria in diabetic patients--14-year follow-up. 未经治疗的糖尿病患者无症状菌尿的临床过程——14年随访。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-07-01
E Semetkowska-Jurkiewicz, S Horoszek-Maziarz, J Galiński, A Manitius, B Krupa-Wojciechowska
{"title":"The clinical course of untreated asymptomatic bacteriuria in diabetic patients--14-year follow-up.","authors":"E Semetkowska-Jurkiewicz,&nbsp;S Horoszek-Maziarz,&nbsp;J Galiński,&nbsp;A Manitius,&nbsp;B Krupa-Wojciechowska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The present study aimed at accessing the natural history of untreated asymptomatic bacteriuria in diabetic patients observed for 14 years. Two groups of diabetic patients were examined. Group I comprised 53 patients with significant bacteriuria, without clinical symptoms of urinary tract infection. Group II consisted of 54 patients with sterile urine. All patients were clinically and bacteriologically examined every 3-6 months for 14 years. The results obtained in this study have proved that clinical symptoms of acute pyelonephritis occur with similar frequency in both groups (group I-6, group II-5 cases). No deterioration of kidney function was found. Arterial hypertension did not differ significantly in both groups at the beginning and end of the follow-up. The usefulness of antibacterial treatment of asymptomatic bacteriuria in diabetic patients is not adequately documented.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 3","pages":"91-5"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19900232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of recombinant human granulocyte colony stimulating factor on granulocytopenia induced by cytotoxic chemotherapy in patients with multiple myeloma. 重组人粒细胞集落刺激因子对细胞毒性化疗所致多发性骨髓瘤患者粒细胞减少的影响。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-07-01
R Pogłód, M Kraj, S Maj
{"title":"Effect of recombinant human granulocyte colony stimulating factor on granulocytopenia induced by cytotoxic chemotherapy in patients with multiple myeloma.","authors":"R Pogłód,&nbsp;M Kraj,&nbsp;S Maj","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>15 multiple myeloma patients with severe granulocytopenia after chemotherapy were treated with recombinant human granulocyte colony stimulating factor (Neupogen; Roche). Granulocyte colony stimulating factor (G-CSF) was given s.c. usually in a dose of 5 micrograms/kg for 5-14 (median:8) days. In all cases the increase in ANC was observed; one day after completing therapy the ANC ranged from 2.3 to 19.7 (mean: 10.3) x 10(9)/l. In 3 cases the ANC peak appeared during first (2-4) days of treatment, in one- on 14-th day after 10-day unsuccesful treatment. Generally, ANCs rapidly decreased after discontinuation of treatment to the values observed prior to the last chemotherapy. Both adverse events present in 9 patients and changes in monitored blood biochemistry components were moderate and reversible. In 3 cases symptoms of myeloma progression occurred. The study showed that G-CSF is an efficient and well tolerated drug, but also demonstrated its short-term action.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 3","pages":"83-9"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19900233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pancreatic islet cell hyperplasia associated with experimental ulcerative colitis in rats. 胰岛细胞增生与实验性溃疡性结肠炎的关系。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-07-01
W Bednarz, R Wojczys, J Doliński
{"title":"Pancreatic islet cell hyperplasia associated with experimental ulcerative colitis in rats.","authors":"W Bednarz,&nbsp;R Wojczys,&nbsp;J Doliński","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ulcerative colitis in Buffalo rats was induced by acetic acid introduced into sigmoid colon. In specimens of the colon and head of the pancreas obtained via laparotomy after seven-day colitis ulcerosa and simultaneously the pancreatic islet cell hyperplasia were histologically observed. Further investigations, especially immunological studies, of these amazing findings are necessary to elucidate the mechanism of the abore relationship.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 3","pages":"119-22"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19898765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Actin content and polymerization in tumour, liver and serum of the hepatoma Morris 5123 tumour bearing rats. Morris 5123肝癌大鼠肿瘤、肝脏及血清中肌动蛋白含量及聚合。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-07-01
M Malicka-Błaszkiewicz, I Styczeń, D Nowak, H Hańczycowa, P Ponikowski, T Sebzda
{"title":"Actin content and polymerization in tumour, liver and serum of the hepatoma Morris 5123 tumour bearing rats.","authors":"M Malicka-Błaszkiewicz,&nbsp;I Styczeń,&nbsp;D Nowak,&nbsp;H Hańczycowa,&nbsp;P Ponikowski,&nbsp;T Sebzda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Monomeric G-actin, total actin and filamentous F-actin were examined during the growth of experimental tumour hepatoma Morris 5123. Actin was measured by the inhibition of the standard DNase I from bovine pancreas. A remarkable increase in total actin, and F-actin content, as well as in the state of actin polymerization (measured by the F:G actin ratio) was shown in the cytosol of the tumour cells in the second week of the tumour growth, followed by a rapid decrease in the third week. Parallel observations were made in the cytosol of the liver and in the serum of the tumour bearing rats. The results were compared with the data obtained for control healthy rats. It was shown that hepatoma Morris tumour growth is accompanied by the changes in the actin content and polymerization, occurring also in the liver of the host animal. Only G-actin was found in the serum. It increased significantly in the second week of tumour growth as compared with the G-actin level in the serum of the control healthy rats.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 3","pages":"115-8"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19898766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信