Russian Journal of General Chemistry最新文献

Glycosides of 4-[2-(Hydroxyphenyl)ethen-1-yl]-1,2,3-thia- and Selenodiazoles Based on Natural 4-(Hydroxyphenyl)but-3-en-2-ones 基于天然4-（羟基苯基）-3-烯-2-酮的4-[2-（羟基苯基）乙烯-1-基]-1,2,3-烯-和硒二唑苷

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-10-07 DOI: 10.1134/S1070363225603163

N. V. Lebedeva, L. M. Pevzner, M. L. Petrov, A. V. Stepakov

引用次数: 0

Substituted Phenylthiazole Derivatives: Synthesis, Spectral and Biological Investigation 取代苯噻唑衍生物：合成、光谱和生物学研究

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-10-07 DOI: 10.1134/S1070363225600742

Nazma Khatun, Md. Din Islam, Ranajit Kumar Sutradhar

{"title":"Substituted Phenylthiazole Derivatives: Synthesis, Spectral and Biological Investigation","authors":"Nazma Khatun, Md. Din Islam, Ranajit Kumar Sutradhar","doi":"10.1134/S1070363225600742","DOIUrl":"10.1134/S1070363225600742","url":null,"abstract":"The present study aimed to synthesize and characterize a group of novel phenylthiazoles and, finally, discovered their antioxidant and antimicrobial efficacy in reducing infectious diseases. The agar disk diffusion method evaluated their antimicrobial efficacies against fungal strains (Aspergillus niger, Trichoderma harzianum), gram-positive (Staphylococcus aureus, Bacillus megaterium), and gram-negative (Salmonella typhi, Escherichia coli) bacterial strains. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and total antioxidant capacity (TAC) methods were used to measure their antioxidant efficacies. Among the tested analogs, we detected the maximum antifungal efficacy for 4-{[2-(4-phenylthiazol-2-yl)hydrazineylidene]methyl}phenol, followed by 2-[2-(4-chlorobenzylidene)hydrazineyl]-4-phenylthiazole. Nevertheless, 5-bromo-2-{[2-(4-phenylthiazol-2-yl)hydrazineylidene]methyl}phenol produced the lowest inhibition zone against T. harzianum. However, the antifungal efficacies for the synthesized compounds were significantly higher than the standard amphotericin B. In contrast, the highest efficacy of the compound 4-{[2-(4-phenylthiazol-2-yl)hydrazineylidene]methyl}phenol is 1.3 times greater than Amphotericin B. Besides, the highest antibacterial efficacy was detected for 4-{[2-(4-phenylthiazol-2-yl)hydrazineylidene]methyl}phenol, followed by 2-[2-(4-chlorobenzylidene)hydrazineyl]-4-phenylthiazole, which was 0.4 times lower than standard ceftriaxone. Moreover, the lowest inhibition zones were achieved for 5-(diethylamino)-2-{[2-(4-phenylthiazol-2-yl)hydrazineylidene]methyl}phenol. The antioxidant screening was done using DPPH free radical inhibition capability and TAC methods. However, both methods ensured that 5-(diethylamino)-2-{[2-(4-phenylthiazol-2-yl)hydrazineylidene]methyl}phenol is a highly potent antioxidant.","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 9","pages":"2424 - 2433"},"PeriodicalIF":0.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanoparticles Formed from Europium Complexes with Diphenylphosphoryl-Substituted 1,3-Diketone Derivatives As Chemically Stable Luminescent Thermosenors 铕配合物与二苯基磷酸基取代1,3-二酮衍生物形成的纳米颗粒作为化学稳定的发光热传感器

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-10-07 DOI: 10.1134/S1070363225605125

Rustem R. Zairov, Alexey P. Dovzhenko, Vadim A. Vasiliev, Timur A. Kornev, Mohsin Ali, Alexey N. Masliy, Viktor V. Syakaev, Irina S. Ryzhkina, Cong Yu, Dmitry Tatarinov, Vladimir Mironov, Oleg G. Sinyashin, Asiya R. Mustafina

{"title":"Nanoparticles Formed from Europium Complexes with Diphenylphosphoryl-Substituted 1,3-Diketone Derivatives As Chemically Stable Luminescent Thermosenors","authors":"Rustem R. Zairov, Alexey P. Dovzhenko, Vadim A. Vasiliev, Timur A. Kornev, Mohsin Ali, Alexey N. Masliy, Viktor V. Syakaev, Irina S. Ryzhkina, Cong Yu, Dmitry Tatarinov, Vladimir Mironov, Oleg G. Sinyashin, Asiya R. Mustafina","doi":"10.1134/S1070363225605125","DOIUrl":"10.1134/S1070363225605125","url":null,"abstract":"This work presents novel diphenylphosphoryl-substituted 1,3-diketone derivatives and demonstrates their potential as ligands for the design of Eu3+-containing nanoparticles with reproducible thermally dependent photoluminescence. Structural analysis of the synthesized lanthanide complexes in acetonitrile medium using NMR, IR spectroscopy, and computational modeling revealed weak coordination of the phosphoryl group to the central Ln3+ ion. Nevertheless, the presence of this group in the ligand molecule enhances the sensitization efficiency of Eu3+ luminescence due to a shielding effect. This effect was confirmed by comparing the quantum yields of Eu3+ complexes with diphenylphosphoryl-substituted 1,3-diketone ligands to their structural analogs lacking the phosphoryl group. The shielding of the lanthanide coordination sphere by the diphenylphosphoryl substituent promotes more efficient incorporation of the complexes into polystyrene sulfonate nanoparticles. The resulting polyelectrolyte colloids exhibit chemically stable luminescent properties in the presence of biologically relevant amino acids and phosphates. Additionally, they demonstrate reproducible thermally dependent luminescence in the biologically relevant temperature range of 25–50°C, with a sensitivity of 1.73–1.76%/°C.","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 9","pages":"2374 - 2389"},"PeriodicalIF":0.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145237008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Michael Adduct of Levoglucosenone and α-Carboethoxycyclododecanone in the Synthesis of a Chiral Spirocyclobutanone 左旋葡萄糖酮与α-碳乙氧基环十二酮加合物在手性螺环丁酮合成中的应用

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-10-07 DOI: 10.1134/S107036322560417X

Yu. S. Galimova, Sh. M. Salikhov, L. Kh. Faizullina

引用次数: 0

Comparison of Vanadium- and Niobium-Containing MgAlCrNi-Based Alloys for Ni-MH Batteries 镍氢电池用含钒和含铌mgalcrni基合金的比较

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-10-07 DOI: 10.1134/S1070363225603102

G. Çakmak, H. Yüce

引用次数: 0

Multicomponent Reaction of Indole with Formaldehyde, Carbon Disulfide, and Amines 吲哚与甲醛、二硫化碳和胺的多组分反应

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-10-07 DOI: 10.1134/S1070363225604260

V. R. Akhmetova, D. V. Leont’ev, V. R. Nigmatullina, E. A. Paramonov, N. F. Galimzyanova, A. S. Ryabova

引用次数: 0

Computational Investigation on the Tautomerisation between (Z)-4-[Hydroxy(phenyl)methylene]isochroman-1,3-dione and 4-Benzoyl-3-hydroxy-1H-isochromen-1-one in S0 and S1 States (Z)-4-[羟基（苯基）亚甲基]异色-1,3-二酮与4-苯甲酰-3-羟基- 1h -等色-1- 1在50态和S1态的互变异构化计算研究

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-10-07 DOI: 10.1134/S1070363225601474

Goutam Dey, Abhijit Chakraborty

{"title":"Computational Investigation on the Tautomerisation between (Z)-4-[Hydroxy(phenyl)methylene]isochroman-1,3-dione and 4-Benzoyl-3-hydroxy-1H-isochromen-1-one in S0 and S1 States","authors":"Goutam Dey, Abhijit Chakraborty","doi":"10.1134/S1070363225601474","DOIUrl":"10.1134/S1070363225601474","url":null,"abstract":"The tautomerization pathway between (Z)-4-[hydroxy(phenyl)methylene]isochroman-1, 3-dione (PHIC) and 4-benzoyl-3-hydroxy-1H-isochromen-1-one (PHOC) was explored both in the S0 and S1 states through DFT and ab initio methods involving 6-31 G(d) basis. The former was found to be the global minimum in both the states, but the orientation of the phenyl ring changes substantially on excitation. Potential energy curves were explored with the variation of proton transfer coordinate and the phenyl rotation. IRC computations identify the transition states and the reaction force and force constants specify the transition region. PHOC is about 3.5±0.5 kcal/mol higher in S0. This difference increases in S1. Maximum hardness principle is obeyed only by the TS. The frontier molecular orbitals confirm the S0→S1 transition as π–π* in nature. All the vibrational signatures in the tautomers were identified. A number of low-frequency modes below 100 cm–1 arises due to the phenyl rotations.","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 9","pages":"2434 - 2444"},"PeriodicalIF":0.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The NBS-Induced Oxidative Sulfonamidation of Natural Monoterpene Ketones l-Carvone and l-Verbenone in Acetonitrile nbs诱导天然单萜酮-香芹酮和-马鞭草酮在乙腈中的氧化磺化反应

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-10-07 DOI: 10.1134/S1070363225604168

I. A. Garagan, V. S. Myasnikova, M. Yu. Moskalik, T. N. Borodina, S. V. Zinchenko, B. A. Shainyan

引用次数: 0

Investigation of Some Substituted-Piperidine-3-carboxamide Derivative Compounds As Active Ingredients in the Treatment of Crohn’s Disease by Molecular Docking Method 分子对接法研究取代哌啶-3-羧酸酰胺衍生物治疗克罗恩病的活性成分

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-10-07 DOI: 10.1134/S107036322560256X

Fatih İslamoğlu

{"title":"Investigation of Some Substituted-Piperidine-3-carboxamide Derivative Compounds As Active Ingredients in the Treatment of Crohn’s Disease by Molecular Docking Method","authors":"Fatih İslamoğlu","doi":"10.1134/S107036322560256X","DOIUrl":"10.1134/S107036322560256X","url":null,"abstract":"In this study, was investigated the feasibility of using some substituted piperidine-3-carboxamide derivative compounds, which have never been synthesized before and have not been included in the literature, for the treatment of Crohn’s disease, a chronic, inflammatory bowel disease that can affect any part of the digestive system, by molecular docking method. For this purpose, fifty different piperidine-3-carboxamide derivative molecules were used in molecular docking studies with nine different proteins using the Auto Dock Vina program. Among the molecules, the highest docking score of –12.8 kcal/mol was obtained between the compound 1-(2-{2-(4-bromophenyl)-4-[(E)-2-phenylhydrazinylidene]-1,2-dihydro-1,3,5-triazin-6-yl}ethyl)piperidine-3-carboxamide and the protein with PDB code 1KMV. Boiled-egg graphs and bioavailability radars were drawn for the ten molecules with the highest docking scores among the fifty studied molecules. Quantum mechanical parameters include highest occupied molecular orbital energy (EHOMO), lowest unoccupied molecular orbital energy (ELUMO), chemical potential (μ), electron affinity (EA), global softness (S), global hardness (η), ionization potential (IP), dipole moments, and electrophilicity (ω) were also analyzed. Finally, bond angles, bond lengths, and molecular electrostatic potential (MEP) were calculated, and a mechanism for the synthesis of this ideal molecule to be used in the treatment of Crohn’s disease was proposed.","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 9","pages":"2573 - 2585"},"PeriodicalIF":0.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis of Polyfluorodiaryls by Desulphurization of Polyfluorodiaryldisulfanes and Polyfluorodiarylsulfanes under the Action of Copper 铜作用下多氟二芳基二砜和多氟二芳基砜脱硫合成多氟二芳基

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-10-07 DOI: 10.1134/S1070363225603278

P. V. Nikul’shin, A. M. Maksimov, A. S. Vinogradov, V. E. Platonov

引用次数: 0