Russian Journal of General Chemistry最新文献_第10页

Reaction of (Z)-N-Substituted α,β-Dehydroamino Acids Hydrazides with Oxazolones. Antiradical Activity of Bishydrazides and Bisimidazole-4-ones (Z)- n -取代α，β-脱氢氨基酸酰肼与恶唑酮的反应。双吡唑类和双咪唑-4-酮的抗自由基活性

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-08-05 DOI: 10.1134/S1070363225602480

S. H. Mangasaryan, A. G. Agababyan, A. A. Shahkhatuni, A. G. Ayvazyan, V. O. Topuzyan

{"title":"Reaction of (Z)-N-Substituted α,β-Dehydroamino Acids Hydrazides with Oxazolones. Antiradical Activity of Bishydrazides and Bisimidazole-4-ones","authors":"S. H. Mangasaryan, A. G. Agababyan, A. A. Shahkhatuni, A. G. Ayvazyan, V. O. Topuzyan","doi":"10.1134/S1070363225602480","DOIUrl":"10.1134/S1070363225602480","url":null,"abstract":"The reaction of (Z)-N-substituted α,β-dehydroamino acid hydrazides with 5(4H)-oxazolones was studied. Optimal reaction conditions were found. It was shown that in addition to the main product, bishydrazide, monoimidazolоne hydrazide was also formed. Substituted bishydrazides, N,N-[(2Z,2′Z)-hydrazine-1,2-diyl-bis(1-oxo-3-phenylprop-2-ene-1,2-diyl)]dibenzamides, were converted into the corresponding bisimidazolones—4,4′-di[(Z)-benzylidene]-2,2′-diphenyl-[1,1′-biimidazole]-5,5′(4H,4′H)-diones. Antiradical properties of the synthesized compounds were studied. It was shown that bishydrazides exhibit higher antiradical activity than the corresponding bisimidazolones and monoimidazolonehydrazide. UV spectra of the synthesized compounds were studied, their molar extinction coefficients at λmax were determined. Structure of 4,4′-di[(Z)-benzylidene]-2,2′-diphenyl-[1,1′-bisimidazole]-5,5′(4H,4′H)-dione was determined by single crystal X-ray diffraction analysis.","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 7","pages":"1791 - 1803"},"PeriodicalIF":0.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145162188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, Characterization, and Molecular Docking of New Heterocyclic Compounds with Evaluation of Their Biological Activities 新型杂环化合物的合成、表征、分子对接及其生物活性评价

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-08-05 DOI: 10.1134/S1070363225602479

N. J. Bagy, M. I. Kadhim

{"title":"Synthesis, Characterization, and Molecular Docking of New Heterocyclic Compounds with Evaluation of Their Biological Activities","authors":"N. J. Bagy, M. I. Kadhim","doi":"10.1134/S1070363225602479","DOIUrl":"10.1134/S1070363225602479","url":null,"abstract":"This study aims to synthesize and perform a molecular docking study of some new heterocyclic compounds to evaluate their biological activity. The synthetic method includes several steps: formation of a new Schiff base via reaction of 5-amino-1,3,4-thiadiazole-2-thiol and 2-formylpyridine in an acidic medium and subsequent transformation to new heterocyclic compounds. The biological activity against two types of bacteria (Escherichia coli and Staphylococcus bacteria) was studied, the results showed good activity for some of these derivatives toward both targeted bacteria. The cytotoxicity of some of the synthesized derivatives was tested in vitro against esophageal cancer cell lines SK-GT-4, the results revealed that 8-hydroxy-3-(5-mercapto-1,3,4-thiadiazol-2-yl)-2-(pyridin-2-yl)-2H-benzo[e][1,3]thiazin-4(3H)-one and 5-[(1H-indol-3-yl)methyl]-3-(5-mercapto-1,3,4-thiadiazol-2-yl)-2-(pyridin-2-yl)imidazolidin-4-one exhibited inhibitory activity for SK-GT-4 with IC50 values of 115.4 and 44.21μg/mL, respectively. A molecular docking study of these compounds confirmed the obtained results.","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 7","pages":"1782 - 1790"},"PeriodicalIF":0.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145162189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Catalytic Performance and Mechanism of Iron meso-Tetra(4-carboxyphenyl)porphine for Oxygen Reduction Reaction 中介四（4-羧基苯基）铁卟啉在氧还原反应中的催化性能及机理

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-08-05 DOI: 10.1134/S1070363225601243

X. Liu, Q.-x. Yue, Y.-h. Wang, M.-d. Lei, Y.-l. Zhang, Y.-w. Zhang, A.-l. Ji, Y.-c. Zhang, X.-q. Zhang, R. Ding, J. Liu

{"title":"Catalytic Performance and Mechanism of Iron meso-Tetra(4-carboxyphenyl)porphine for Oxygen Reduction Reaction","authors":"X. Liu, Q.-x. Yue, Y.-h. Wang, M.-d. Lei, Y.-l. Zhang, Y.-w. Zhang, A.-l. Ji, Y.-c. Zhang, X.-q. Zhang, R. Ding, J. Liu","doi":"10.1134/S1070363225601243","DOIUrl":"10.1134/S1070363225601243","url":null,"abstract":"The catalytic performance and mechanism of the prepared iron meso-tetra (4-carboxyphenyl) porphyrin (FeTCPP) on oxygen reduction reaction in alkaline environments were studied. At high concentrations of FeTCPP, the oxygen reduction reaction followed an efficient direct 4-electron transfer mechanism instead of 2+2 electron transfer mechanism. The central iron ion in FeTCPP underwent redox reactions from FeIII to FeII. O2 molecules formed a superoxide anion coordination complex with FeIITCCP, transferring an electron from the central iron ion. Protonation of the complex formed a superoxide hydrogen radical complex, which then acquired another electron, generating a hydroperoxide radical and completing the first 2-electron reduction. The peroxide formed a coordination complex with FeIITCCP to produce a peroxide complex FeIIITCCP:O2– with intramolecular charge transfer. And then it acquired two electrons, completing the second 2-electron reduction and being reduced to OH–. When the concentration of FeIIITCCP was high, the complex FeIIITCCP:O2– could protonate without stepwise reactions, directly acquiring three electrons from the electrode surface and being reduced to OH–. The oxygen reduction reaction exhibited a 4-electron mechanism. Both the 2+2 and 4-electron pathways occurred simultaneously, with the 4-electron pathway becoming more prominent as the concentration of FeTCPP increased.","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 7","pages":"1670 - 1685"},"PeriodicalIF":0.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145162325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research Progress on Ferrocene-Based Metal Compound Catalyst Precursor in Ammonium Perchlorate Composite Solid Propellants (A Review) 高氯酸铵复合固体推进剂中二茂铁基金属化合物催化剂前驱体的研究进展

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-08-05 DOI: 10.1134/S1070363225600535

Xiaoju Liu, Qinsong Wang, Xiaoyan Ma

{"title":"Research Progress on Ferrocene-Based Metal Compound Catalyst Precursor in Ammonium Perchlorate Composite Solid Propellants (A Review)","authors":"Xiaoju Liu, Qinsong Wang, Xiaoyan Ma","doi":"10.1134/S1070363225600535","DOIUrl":"10.1134/S1070363225600535","url":null,"abstract":"Ammonium perchlorate-based composite solid propellants (AP-CSPs) are of paramount importance in aerospace, military, and other fields. Ferrocene-based metal compounds as a precursor of the active phase of the catalyst formed in the combustion wave. They are characterized by their unique chemical structures, can effectively regulate the combustion performance of AP-CSPs even at low dosages. Nevertheless, traditional ferrocene-based catalyst precursor (Fc-CPs), especially those with simple structures and low molecular weights, are highly prone to migration, which severely compromises the storage life, operational reliability, and environmental adaptability of the propellants. To address these issues, the development of ferrocene-based metal compound catalyst precursor (Fc-MC-CPs) with low migration and high catalytic efficiency has emerged as a prominent research focus. Fc-MC-CPs offer significant improvements over traditional Fc-CPs. Specifically, some Fc-MC-CPs exhibit a migration rate up to 50% lower than their traditional counterparts, which directly mitigates the negative impacts on propellant storage, operation, and adaptability. Moreover, they can increase the burning rate of AP-CSPs by over 30%, demonstrating superior catalytic performance. This review summarizes the recent research progress of Fc-MC-CPs in AP-CSPs. It details the reported synthesis methods, assesses their antimigration, volatility, and catalytic properties, and analyzes the existing problems. Based on these insights, it also discusses the future research directions, providing crucial theoretical and practical references for subsequent studies. The ultimate goal is to optimize the performance of Fc-MC-CPs in AP-CSPs and promote the development of related fields.","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 7","pages":"1631 - 1648"},"PeriodicalIF":0.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145162326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hot Melt Extrusion Assisted Synthesis of 3-Methyl-4-arylmethyleneisoxazole-5(4H)-ones: A Continuous and Sustainable Approach 热熔挤压辅助合成3-甲基-4-芳基亚甲基二恶唑-5(4H)- 1：连续和可持续的方法

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-08-05 DOI: 10.1134/S1070363225601218

K. S. More, P. D. Nikam, Y. U. Gadkari

引用次数: 0

Synthesis of New Taurine Derivatives by Reaction of 2-Aryl-1-(vinylsulfonyl)pyrrolidines with Optically Pure Amines 2-芳基-1-（乙烯基磺酰基）吡咯烷与光学纯胺反应合成新型牛磺酸衍生物

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-08-05 DOI: 10.1134/S1070363225602145

S. M. Nakypova, A. V. Smolobochkin, A. S. Gazizov, D. P. Gerasimova, N. I. Akylbekov, A. R. Burilov

引用次数: 0

Synthesis and Analgesic Activity of N,N′-(Ethane-1,2-diyl)bis(spiroazetidin-2ones) Containing Cyclobutane, Cyclopentane or Cyclohexane Fragments 含环丁烷、环戊烷或环己烷片段的N，N ' -（乙烷-1,2-二基）二（spiroazetitin -2ones）的合成及镇痛活性

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-08-05 DOI: 10.1134/S107036322560211X

E. A. Nikiforova, L. A. Vasilenko, R. R. Makhmudov, D. P. Zverev, M. V. Dmitriev, D. V. Baibarodskikh, N. F. Kirillov

引用次数: 0

Hyperbranched Polyaminoethylene Carbonates of the Second and Third Generations and Their Copper(II) Complexes: Synthesis, Structure and Properties 第二代和第三代超支化聚酰胺碳酸酯及其铜（II）配合物的合成、结构和性能

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-08-05 DOI: 10.1134/S1070363225603199

A. F. Maksimov, B. R. Yarullin, Kh. E. Kharlampidi, M. P. Kutyreva, G. A. Kutyrev

{"title":"Hyperbranched Polyaminoethylene Carbonates of the Second and Third Generations and Their Copper(II) Complexes: Synthesis, Structure and Properties","authors":"A. F. Maksimov, B. R. Yarullin, Kh. E. Kharlampidi, M. P. Kutyreva, G. A. Kutyrev","doi":"10.1134/S1070363225603199","DOIUrl":"10.1134/S1070363225603199","url":null,"abstract":"The first representatives of hyperbranched polyaminoethylene carbonates of the second and third generations were synthesized from triethanolamine and dimethyl carbonate. The reaction of these polymers with CuCl2∙2H2O yielded Cu(II) complexes. Structure of hyperbranched macromolecules and Cu(II) complexes was proved by 1H, 13C NMR, IR, UV-Vis spectroscopy, titrimetry, elemental analysis and TGA. By 1H NMR spectroscopy and titrimetry data, hyperbranched polyaminoethylene carbonates of the second and third generations have 11 and 21 terminal hydroxyl groups, branching degree of 0.8 and 0.82, Mn equal to 1782 and 3986 g/mol, respectively. The thermal transformations in the polymers were studied by TGA method. The morphology and hydrodynamic diameter of particles were determined by SEM, CLSM, NTA and dynamic light scattering methods. The temperature dependence of the kinematic viscosity of polymers was revealed, and the refractive index and pH of hyperbranched polymers were determined.","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 7","pages":"1870 - 1881"},"PeriodicalIF":0.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145162182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Explored Routes to (Trifluoropropynyl)borates M[(F3CC≡C)nBF4–n] (n ≥ 2) （三氟丙基）硼酸盐的探索路线M[(F3CC≡C) nBF4-n] （n≥2）

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-08-05 DOI: 10.1134/S1070363225601516

N. Yu. Adonin, V. V. Bardin

引用次数: 0

Synthesis and Characterization of 2,4-Diamino-6-methyl-1,3,5-triazine and 2,4-Diamino-6-phenyl-1,3,5-triazine Doped Polyacid and Their Application to Breast Cancer Studies 2,4-二氨基-6-甲基-1,3,5-三嗪和2,4-二氨基-6-苯基-1,3,5-三嗪掺杂聚酸的合成、表征及其在乳腺癌研究中的应用

IF 0.8 4区化学

Russian Journal of General Chemistry Pub Date : 2025-08-05 DOI: 10.1134/S1070363224609839

J. Selvam, B. Samannan, A. Lazar, R. Kumar, Y.-L. Lin, J. Thavasikani

{"title":"Synthesis and Characterization of 2,4-Diamino-6-methyl-1,3,5-triazine and 2,4-Diamino-6-phenyl-1,3,5-triazine Doped Polyacid and Their Application to Breast Cancer Studies","authors":"J. Selvam, B. Samannan, A. Lazar, R. Kumar, Y.-L. Lin, J. Thavasikani","doi":"10.1134/S1070363224609839","DOIUrl":"10.1134/S1070363224609839","url":null,"abstract":"The current study is involved in the synthesis and characterization of 2,4-diamino-6-methyl-1,3,5-triazine (DMT), and 2,4-diamino-6-phenyl-1,3,5-triazine (DPT) doped polyacid using a co-precipitation method. In addition, polyacid having novel types of structures were synthesized. An efficient and improved procedure for the synthesis of triazine was developed by Silverton-type polyacid. The chemistry of triazine based metal complexes display a variety of reactivity mode and they possess catalytic activities therefore such metal complexes were studied. The doped samples were characterized using spectral techniques such as FT-IR spectra which shows the presence of extended functional groups and SEM morphology exhibits agglomerated structure. XRD results give crystallite size of around 40 nm. Furthermore, the structural and thermal properties of triazine doped polyacid were investigated using UV, TGA and Raman techniques. The antibacterial activity compared to PA and DPT-PA and DMT-PA with improved activity to E. coli and S. aureus was revealed. The anticancer studies of DMT- and DPT-doped polyacid compound was assessed by MTT assay on cell-line MCF-7.","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 7","pages":"1649 - 1659"},"PeriodicalIF":0.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145162184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0