Russian Journal of General Chemistry最新文献

{"title":"Structural Characteristics and Sorption-Desorption Properties of Nanodiamonds Synthesized by Detonation of a Hexogen-Trinitrotoluene Mixture","authors":"Anatolii P. Karmanov,&nbsp;Valery Yu. Dolmatov,&nbsp;Ludmila S. Kocheva,&nbsp;Nataly G. Rachkova","doi":"10.1134/S1070363226602176","DOIUrl":"10.1134/S1070363226602176","url":null,"abstract":"<p>The technogenic human activity leads to contamination of soils, natural water-bodies and, respectively, food products with different toxic compounds, including radionuclides. Detonation nanodiamonds (DND) are promising materials for purifying aqueous media from micro-amounts of uranium. We have studied the sorption properties of carbon nanomaterials with a different content of DND fractions, when used to absorb the U-238 radionuclide. For the first time, the possibility of purifying aqueous media with low uranium content (1.2 mg/L) has been established. To characterise diamond-containing materials (DCMs) and DND samples, we used the methods of X-ray fluorescence analysis, energy-dispersive X-ray spectroscopy, scanning electron microscopy, FTIR spectroscopy, and low-temperature nitrogen adsorption. The studied DCM and DND samples were different by the sorption capacity to uranium that is determined by their chemical composition and surface properties. We identified the correlations between different characteristics and found out that the uranium adsorption value correlates with the following indices of surface-porous structure of samples as SSA_BET and <i>V</i>_micro. The obtained results demonstrate the possibility of using detonation nanodiamonds as adsorbents of uranium.</p>","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"96 8","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148614127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RSM-CCD Optimized Green Synthesis of Quercus suber-Mediated Silver Nanoparticles: Comprehensive Characterization and Potent Antioxidant, Antimicrobial, and Anticancer Activities Against MCF-7 Cells","authors":"Roufaida Aissa Brahim,&nbsp;Hadjer Mabrouki,&nbsp;Muhammad Taher,&nbsp;Djamel Eddine Akretche","doi":"10.1134/S1070363226600141","DOIUrl":"10.1134/S1070363226600141","url":null,"abstract":"<p>This article reports a green synthesis of silver nanoparticles (AgNPs) by a hydroalcoholic extract obtained from aerial parts of <i>Quercus suber</i> L. collected from the Beni Ali region, northern Algeria. By varying sonication time, ultrasonic amplitude, and extract concentration using response surface methodology with central composite design, we optimized the biosynthesis process for maximum nanoparticle formation efficiency. AgNPs were fully characterized using ultraviolet-visible (UV-Vis) spectroscopy, dynamic light scattering (DLS), Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), scanning electron microscopy with energy-dispersive X-ray (SEM-EDX) analysis, thermogravimetric analysis (TGA), and zeta potential measurements to confirm their preliminary physical composition. The analyses confirmed that crystalline and functionalized nanoparticles with the average size of 64.34 nm demonstrated thermal stability throughout the synthesis procedure. AgNPs capped with <i>Q. suber</i> extract showed significant activities in the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays, which indicated that they had potent free radical scavenging and ferric-reducing abilities. Antimicrobial assays showed AgNPs’ inhibition zones were larger than those of plant extract and silver nitrate samples against gram-positive and gram-negative bacteria and fungal strains. A dose-dependent cytotoxic effect was observed on the MCF-7 human breast adenocarcinoma cells, with a half maximal inhibitory concentration IC₅₀ of 122.25 μg/mL, suggesting moderate toxicity and potential therapeutic application. <i>Q. suber</i>-mediated green synthesis of AgNPs has shown potential as an environmentally friendly and easy method. This study sets the stage for <i>in vivo</i> exploration of these biogenic nanoparticles for both therapeutic and environmental applications.</p>","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"96 8","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148614573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and Study of New N-Substituted Pyrazolines with 2,5-Dimethylfuryl and p-Halophenyl Fragments","authors":"Aynur R. Karayeva,&nbsp;Mahruza I. Shatirova,&nbsp;Musa M. Mustafayev,&nbsp;Gulnur M. Mammadova,&nbsp;Shahla K. Sheydayeva","doi":"10.1134/S1070363226600955","DOIUrl":"10.1134/S1070363226600955","url":null,"abstract":"<p>The paper presents the results of a study of an efficient approach to the synthesis of new functionally substituted chalcone and pyrazoline derivatives based on 3-acetyl-2,5-dimethylfuran. The starting chalcones were obtained by aldol-crotonic condensation of 3-acetyl-2,5-dimethylfuran with <i>p</i>-chloro- and <i>p</i>-bromobenzaldehyde. It was found that the reaction of the synthesized 3-(4-halophenyl)-1-(2,5-dimethylfuran-3-yl)prop-2-en-1-ones with hydrazine hydrate and phenylhydrazine in pyridine and ethanol leads to the formation of new 2-pyrazoline derivatives. To obtain <i>N</i>-substituted pyrazolines, the reaction of chalcones with hydrazine hydrate was carried out in ethanol in the presence of formic and acetic acids, which made it possible to selectively modify the pyrazoline core. As a result, a series of new 1-phenyl-, 1-formyl-, and 1-acetyl-substituted 2-pyrazolines containing furyl and chloro-, bromo-substituted phenyl rings in the molecule were synthesized in high yields. The structure and composition of the obtained α,β-unsaturated ketones and 2-pyrazoline derivatives were confirmed by IR, ¹H and ¹³C NMR spectroscopy methods. The obtained results indicate the promise of the developed synthetic approach to the preparation of functionally substituted pyrazolines of interest for further study of biological activity, and also open up opportunities for the targeted synthesis of fused heterocyclic compounds.</p>","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"96 8","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148614313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of Triazole Derivatives of Pillar[5]arene and Their Self-Assembly with Antitumor Fluoropyrimidine Drugs","authors":"Yulia I. Aleksandrova,&nbsp;Dmitriy N. Shurpik,&nbsp;Arseniy I. Igumnov,&nbsp;Arina V. Pergat,&nbsp;Evgeniya V. Subakaeva,&nbsp;Pavel V. Zelenikhin,&nbsp;Ivan I. Stoikov","doi":"10.1134/S1070363226602000","DOIUrl":"10.1134/S1070363226602000","url":null,"abstract":"<p>For the first time, water-soluble triazole derivatives of pillar[5]arene were synthesized. UV-Vis spectroscopy has revealed the formation of associates between pillar[5]arenes with 1,2,3-thiotriazole moieties and antitumor fluoropyrimidine drugs in a macrocycle : drug = 1 : 2 stoichiometric ratio in water. The association constant of the macrocycle with 5-fluorouracil was 5.46 and with floxuridine it was 7.04. Dynamic light scattering demonstrated the self-assembly of the macrocycle containing 1,2,4-thiotriazole fragments into stable associates in water, with a size of 180 nm over the entire concentration range studied (1–100 μM), in contrast to the isomeric pillar[5]arene. The critical aggregation concentration (CAC) for the macrocycle with 1,2,4-thiotriazole was 43 μM and for the pillar[5]arene with 1,2,3-thiothiothriazole it was 110 μM. At the same time, both macrocycles did not show toxicity towards model adenocarcinoma cells (A549) <i>in vitro</i>.</p>","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"96 8","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148614479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid Liposomes with Pyrrolidinium Surfactants for the Encapsulation of Hydrophilic Drugs: Physicochemical Characterization and Cellular Uptake","authors":"Roman A. Babkin,&nbsp;Elmira A. Vasilieva,&nbsp;Leysan A. Vasileva,&nbsp;Alexandra D. Voloshina","doi":"10.1134/S1070363226601821","DOIUrl":"10.1134/S1070363226601821","url":null,"abstract":"<p>Pyrrolidinium amphiphiles bearing a hydroxyethyl fragment [MPS<i>n</i>(OH), where <i>n</i> = 12, 14, 16, 18] were used as a modifier for the preparation of cationic hybrid liposomes based on phosphatidylcholine and cholesterol. The composition of the nanocarriers was optimized by varying the surfactant alkyl chain length and the lipid/surfactant molar ratio. The hydrophilic dye rhodamine B (RhB) was encapsulated into the liposomes with an encapsulation efficiency of up to 79 ± 3%. Incorporation of the cationic surfactants into the lipid bilayer increased the ζpotential from –13 ± 1 to +48 ± 2 mV, while the hydrodynamic diameter remained in the range of 100–130 nm, ensuring colloidal stability of the system. As the surfactant concentration increased, the ζpotential of the hybrid liposomes increased, with the effect being less pronounced for the longer-chain homologues. RhBloaded liposomes modified with MPS<i>n</i>(OH) maintained stable physicochemical characteristics for over 8 months at 4°C. Encapsulation of RhB slowed its release compared to the free dye. Liposomes modified with MPS14(OH) exhibited high intracellular accumulation in both normal (Wi38) and cancer (T98G) cells, with predominant localization in cytoplasm.</p>","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"96 8","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1134/S1070363226601821.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148614207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biogenic Synthesis of Reduced Graphene Oxide Exhibiting Potential Antioxidant and Sonochemical Dye Removal Activities","authors":"Abdul Rahim,&nbsp;Ratnakaram Venkata Nadh,&nbsp;K. Vijaya Lakshmi,&nbsp;Venkat Sai Sriram Mosali,&nbsp;Nagaprasad Puvvada,&nbsp;Rambabu Koyilapu,&nbsp;D. Ramachandran,&nbsp;P. Bharath,&nbsp;Bala Murali Krishna Khandapu,&nbsp;Basavaiah Chandu","doi":"10.1134/S1070363225608300","DOIUrl":"10.1134/S1070363225608300","url":null,"abstract":"<p>Biogenic synthesis of graphene is so fascinating in the current research due to its advantages such as eco-friendliness, sustainability, bulk production of graphene coupled with its applicability in numerous applications. Here we report, biosynthesis of reduced graphene oxide (RGO) by the reduction of graphene oxide (GO) using fenugreek seed extract as a natural reducing agent. A popular Indian culinary component with therapeutic qualities, Trigonella foenum-graecum seeds are rich in phytochemicals that have the potential capacity for reduction and capping abilities. The structure of the thus synthesized graphene is investigated and validated using XRD, Raman, SEM and TEM spectroscopic techniques. The RGO displayed a potential antioxidant activity of 74% against DPPH radical which is higher than the standard ascorbic acid. Furthermore, the RGO also exhibited superior dye removal efficiency (95% within 1 h) when it is sonicated with 4 ppm Rhodamine B dye. These findings suggest that, graphene synthesized via biogenic process demonstrated potential antioxidant and sonochemical dye removal capabilities.</p>","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"96 8","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148614333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microfluidic Reactive Media of Polymers and Surfactants: Modeling and Monitoring of Interactions by Integrated Liquid Crystal","authors":"Artem N. Bezrukov,&nbsp;Yuriy G. Galyametdinov","doi":"10.1134/S1070363226602498","DOIUrl":"10.1134/S1070363226602498","url":null,"abstract":"<p>Liquid crystals represent anisotropic media with orientation and optical properties selectively sensitive to orientants with supramolecular organization such as polymers and surfactants. Microfluidic channels offer new opportunities to control behavior of supramolecular media by specific dynamic and wall effects. This work focuses on characterizing responses of a nematic liquid crystal to polymer and surfactant solutions and their reactive flows in microfluidic confinement. Specific liquid crystalline textures were found to form in microchannels due to a combination of wall effects and the impact of polymer and surfactant solutions. A diffusion-reaction model was used to characterize behavior for microfluidic polymer-surfactant flows. The equations of the model were solved in Matlab to obtain concentration distribution of the interaction products with respect to flow dynamics, diffusivities of the reactants and microchannel geometry. It was shown that diffusion-reaction processes in microfluidic polymer-surfactant media can be monitored by analyzing orientation behavior of the infused liquid crystal and comparing the experimental data with the predictions of the model. The results can contribute to developing analytical chips for monitoring interactions in supramolecular-organized media in microfluidic models of biological capillary systems.</p>","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"96 8","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1134/S1070363226602498.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148614341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MOF-Derived Porous Zn–Fe2O3 Nanozymes for Sensitive Colorimetric Assay of Acetylcholinesterase Activity","authors":"Bin Miao,&nbsp;Jianfeng Xu,&nbsp;Bei Liu,&nbsp;Qianmi Wang,&nbsp;Yanmin Shan,&nbsp;Jingjing Li","doi":"10.1134/S1070363226601870","DOIUrl":"10.1134/S1070363226601870","url":null,"abstract":"<p>Porous Zn–Fe₂O₃ nanozymes were prepared through calcination of a Zn-MIL-53 precursor via a MOF-to-oxide conversion strategy. Benefiting from the self-sacrificial template effect and Zn incorporation, the obtained Zn–Fe₂O₃ retained the spindle-like morphology while developing a hierarchical micro/mesoporous structure with a larger specific surface area than Fe₂O₃. Meanwhile, Zn incorporation increased the Fe²⁺/Fe³⁺ ratio and enriched oxygen vacancy related defects, which collectively facilitated H₂O₂ activation and enhanced the peroxidase-like (POD-like) catalytic oxidation of TMB. As a result, Zn–Fe₂O₃ exhibited significantly higher POD-like activity than Fe₂O₃. Based on this enhanced catalytic performance, an inhibition-type colorimetric assay for acetylcholinesterase was established using acetylthiocholine as the substrate. Under the optimized conditions, the assay showed a linear range of 0–35 mU/mL and a detection limit of 0.144 mU/mL. This work demonstrates that combining MOF-derived porosity with dopant-induced electronic and defect modulation is an effective strategy for developing Fe-based nanozymes for nanozyme-based colorimetric AChE activity assays.</p>","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"96 8","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148614342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thiylation Products of 2(5H)-Furanone Derivatives with 2,2'-Oxydiethanethiol","authors":"Enze S. Rabbanieva,&nbsp;Lien T. Hoang,&nbsp;Margarita Yu. Kuzmicheva,&nbsp;Daria P. Gerasimova,&nbsp;Alsu M. Khabibrakhmanova,&nbsp;Olga A. Lodochnikova,&nbsp;Almira R. Kurbangalieva","doi":"10.1134/S1070363226602309","DOIUrl":"10.1134/S1070363226602309","url":null,"abstract":"<p>The reactivity of mucochloric acid and its 5-substituted derivatives towards 2,2<i>'</i>-oxydiethanethiol was studied. A specific feature of the reaction of mucochloric acid with 2,2<i>'</i>-oxydiethanethiol carried out in the presence of triethylamine was revealed. Compared to previously studied reactions with aliphatic dithiols, minor products of the lactone ring degradation, possessing a propenal fragment, were also isolated in this reaction, along with a bis-thioether of the 2(5<i>H</i>)-furanone series. A series of novel bis-thioethers and thiols containing an unsaturated γ-lactone ring and a dithiol fragment were synthesized and characterized.</p>","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"96 8","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148613621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and Study of Antimicrobial and Antiradical Activity of N-Benzoylmethylamides of N-Substituted α,β-Dehydroamino Acids and the Corresponding Imidazol-4-ones","authors":"Asmik G. Agababyan,&nbsp;Anna G. Sukiasyan,&nbsp;Armen A. Hovhannisyan,&nbsp;Astghik A. Shahkhatuni,&nbsp;Sirvard G. Mangasaryan,&nbsp;Roza A. Madoyan,&nbsp;Samvel G. Chailyan,&nbsp;Vigen O. Topuzyan","doi":"10.1134/S1070363226600736","DOIUrl":"10.1134/S1070363226600736","url":null,"abstract":"<p>The synthesis of <i>N</i>-benzoylmethylamides of <i>N</i>-substituted α,β-dehydroamino acids and the corresponding 4<i>H</i>-imidazol-4-ones was carried out; their antibacterial, antifungal, and antiradical properties were studied. It was shown that among them, the compounds containing a nitro group in the <i>meta</i>- or <i>para</i>-position of the benzene ring of the arylidene residue exhibited the highest activity against <i>E. coli</i>, <i>St. aureus</i>, and <i>Candida albicans</i>.</p>","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"96 8","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148613689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}