Infusionstherapie und klinische Ernahrung最新文献_第9页

[Clinical studies of peripheral venous parenteral nutrition. Effect of a 3.5% amino acid solution on postoperative metabolism with special reference to amino acid homeostasis]. 外周静脉肠外营养的临床研究。3.5%氨基酸溶液对术后代谢的影响[特别参考氨基酸稳态]。

Infusionstherapie und klinische Ernahrung Pub Date : 1987-02-01

R Dölp, A Grünert, E Schmitz, F W Ahnefeld

引用次数: 0

[6th joint annual meeting: German Society for Artificial Nutrition and the Austrian Society for Clinical Nutrition. Augsburg, 26-29 March 1987. Abstracts]. 第六届联合年会:德国人工营养学会和奥地利临床营养学会。奥格斯堡，1987年3月26日至29日。摘要]。

Infusionstherapie und klinische Ernahrung Pub Date : 1987-02-01

引用次数: 0

[Parenteral use of a fat emulsion in the early postoperative period]. [术后早期静脉注射脂肪乳剂]。

Infusionstherapie und klinische Ernahrung Pub Date : 1987-02-01

B Weidler, H J Prinzler, B von Bormann, E Lohmann, K H Muhrer, G Hempelmann

{"title":"[Parenteral use of a fat emulsion in the early postoperative period].","authors":"B Weidler, H J Prinzler, B von Bormann, E Lohmann, K H Muhrer, G Hempelmann","doi":"","DOIUrl":"","url":null,"abstract":"Parenteral application of fat emulsions has been established as useful in long term artificial nutrition especially during weaning off the ventilator. In order to ascertain whether these advantages can also be proved in nonventilated patients in the immediate postoperative phase, alternatively carbohydrates versus a new fat emulsion were investigated. 30 patients were randomly allocated to three different nutrition regimens. The caloric and nitrogen supplementation was identical for all groups, while the carbohydrate and fat content was different. Group I: only carbohydrates (as caloric source), group II: high fat load (3 g/kg/day), group III: medium fat dosage (1.5 g/kg/day). Routine laboratory parameters as well as acid-base-status and fat metabolism were evaluated. While most of the routine parameters were not significantly different between the groups, triglyceride levels in serum were highest in group II but never exceeding 280 mg/dl (-x). Nitrogen balance as well as protein metabolism were significantly improved using regimen III, thus documenting the beneficial effect of a medium fat dosage in the immediate postoperative phase. Parenteral nutrition combining amino acids, carbohydrates and a fat emulsion seems to be the optimal postoperative regimen even in patients without ventilatory support.","PeriodicalId":75931,"journal":{"name":"Infusionstherapie und klinische Ernahrung","volume":"14 Suppl 1 ","pages":"28-39"},"PeriodicalIF":0.0,"publicationDate":"1987-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14236788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Effect of lipid emulsions on nitrogen balance within the scope of perioperative parenteral feeding regimens]. [围手术期肠外喂养方案范围内脂质乳对氮平衡的影响]。

Infusionstherapie und klinische Ernahrung Pub Date : 1987-02-01

J Hayungs, V Michalczik, F Borchard, L M Herbertz, W Stock, H Reinauer

{"title":"[Effect of lipid emulsions on nitrogen balance within the scope of perioperative parenteral feeding regimens].","authors":"J Hayungs, V Michalczik, F Borchard, L M Herbertz, W Stock, H Reinauer","doi":"","DOIUrl":"","url":null,"abstract":"Patients with colorectal cancer were parenterally fed before and after surgery by two different isocaloric regimens: One group was infused with high carbohydrate solutions (carbohydrate group), the other group with carbohydrate in combination with fat emulsions (fat group). The daily dose of fat was restricted to 1 g fat/kg BW/day. These conditions led to the following results: No significant changes in the protein balance were observed between the patients of the two regimens. The protein sparing effect and the synthesis of short living proteins were comparable. The infused fat emulsions were utilized without metabolic complications. Patients in the fat group were adequately supplied with essential fatty acids which was documented by the higher level of linolic acid in the blood. The biochemical and histological analysis of the liver samples which were excised on occasion of surgery gave comparable triglyceride content in both groups. In the fat group little lipid deposition was seen in the parenchymal cells but lipid droplets were observed in the reticuloendothelial system (v. Kupffer cells). Thus, distribution of fat droplets is different in the 2 groups. Unfortunately analysis of lipid depositions in the liver at the end of the parenteral nutrition could not be performed.","PeriodicalId":75931,"journal":{"name":"Infusionstherapie und klinische Ernahrung","volume":"14 1","pages":"23-34"},"PeriodicalIF":0.0,"publicationDate":"1987-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14239044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The intravenous 15N metabolism test in assessing the effect of parenteral feeding on protein synthesis]. [静脉内15N代谢试验评价肠外喂养对蛋白质合成的影响]。

Infusionstherapie und klinische Ernahrung Pub Date : 1986-12-01

R Matkowitz, P Junghans, W Hartig, K Jung, H Faust, A Pester, R Ritter

引用次数: 0

[Biological availability of glutamine from N-acetyl-L-glutamine in intravenous administration. Studies in the rat]. n -乙酰- l-谷氨酰胺在静脉给药中的生物利用度。在老鼠身上的研究]。

Infusionstherapie und klinische Ernahrung Pub Date : 1986-12-01

M Neuhäuser, K H Bässler

{"title":"[Biological availability of glutamine from N-acetyl-L-glutamine in intravenous administration. Studies in the rat].","authors":"M Neuhäuser, K H Bässler","doi":"","DOIUrl":"","url":null,"abstract":"Glutamine may be important especially in the catabolic patient, due to its universal role in transamination reactions. Because of its instability, until presently, glutamine is not included in amino acid solutions for parenteral nutrition. The availability of glutamine from the stable derivate N-acetyl-L-glutamine is investigated under the condition of a long-term parenteral nutrition by means of growth, N-balance, and amino acid concentrations in plasma, muscle and urine. For this purpose 2 groups of young healthy male rats (n = 6) are maintained entirely by parenteral nutrition for 12 days. Both groups are given 0.8 g N/kg/24 h as an amino acid solution without containing glutamine. Only one of the groups was supplied additionally with 0.4 g N as N-acetyl-L-glutamine. This resulted in a weight gain of 33 +/- 1.5 g and a cumulative N-balance of 1.5 +/- 0.045 g. In the group in which no acetyl-L-glutamine is given, weight gain is 27 +/- 1.8 g (p less than 0.05) and cumulative N-balance amounts only 1.16 +/- 0.034 g (p less than 0.001). In plasma and urine the amino acid concentrations are significantly elevated for the essential one in this group. The results indicate a good availability of glutamine from N-acetyl-L-glutamine when given intravenously to the rat.","PeriodicalId":75931,"journal":{"name":"Infusionstherapie und klinische Ernahrung","volume":"13 6","pages":"292-6"},"PeriodicalIF":0.0,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14234279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Comparative studies of the metabolism of MCT/LCT and LCT emulsions in diabetics]. 【糖尿病患者MCT/LCT与LCT乳剂代谢的比较研究】。

Infusionstherapie und klinische Ernahrung Pub Date : 1986-12-01

M Wicklmayr, K Rett, G Dietze, H Mehnert

引用次数: 0

[Amino acid administration in acute, compensated renal failure in the post-traumatic phase]. [氨基酸在创伤后急性代偿性肾功能衰竭中的应用]。

Infusionstherapie und klinische Ernahrung Pub Date : 1986-12-01

E Bock

{"title":"[Amino acid administration in acute, compensated renal failure in the post-traumatic phase].","authors":"E Bock","doi":"","DOIUrl":"","url":null,"abstract":"Three patient groups compensated acute renal failure and previous surgery were evaluated, who had been nourished isocaloric (1700 kcal) and practically isonitrogen (33-35 g amino acid), but of various mixtures of amino acids. Besides the uniform daily energy intake of 750 ml of 40% invert sugar and 250 ml of 20% Lipofundin, the daily amino acid infusion of group I (n = 13) was only 500 ml EAS pfrimmer (34.5 g), of group II (n = 10) 250 ml EAS pfrimmer and 250 ml of 7.5% Intrafusin, and of group III (n = 16) 250 ml EAS pfrimmer and 350 ml Aminofusin Hepar (33.1 g). During evaluation of the aminograms, low initial values under the bottom reference region of glycine, serine, arginine and histidine in serum were recorded at the start of the trial in all 3 patient groups. During the course of the 4-day infusion therapy, the serum values of patients in groups II and III appeared to improve more than those in group I. Contrarily, the serum levels of phenylalanine, methionine and 3-methyl histidine were 2-3 times higher than the reference region at the start of the trial. With regard to a decrease in the high serum levels, patient group II appeared to be superior to groups I and III. No significant differences were observed during the clinical course.","PeriodicalId":75931,"journal":{"name":"Infusionstherapie und klinische Ernahrung","volume":"13 6","pages":"254-60"},"PeriodicalIF":0.0,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14233585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elimination of amino acids in chronic renal failure. 慢性肾衰竭中氨基酸的消除。

Infusionstherapie und klinische Ernahrung Pub Date : 1986-12-01 DOI: 10.1159/000222158

W Druml, G Kleinberger, U Bürger, P Balcke, A Laggner, K Lenz, P Schmidt, J Zazgornik

{"title":"Elimination of amino acids in chronic renal failure.","authors":"W Druml, G Kleinberger, U Bürger, P Balcke, A Laggner, K Lenz, P Schmidt, J Zazgornik","doi":"10.1159/000222158","DOIUrl":"https://doi.org/10.1159/000222158","url":null,"abstract":"Elimination of parenterally administered amino acids was investigated in patients with chronic renal failure (CRF) (10 on conservative treatment = CT, 13 on regular hemodialysis therapy = HD). In a bolus injection protocol 0.1 g amino acids as a 10% solution containing essential and nonessential amino acids were infused and pharmacokinetic parameters of 17 amino acids were calculated. The mean elimination half life was increased by 40% in CT and 87% in HD (p less than 0.001 CT and HD versus controls). Total clearance was reduced in CT (p less than 0.001 versus HD and controls). In CT clearance of phenylalanine, proline, alanine, histidine and arginine was reduced, of none of the amino acids elevated. In HD clearance of methionine, lysine, aspartic acid and serine was increased, of proline decreased. The total transfer rate was reduced in CT (p less than 0.025 versus controls) and transfer of threonine, aspartic acid, glutamic acid, alanine, histidine and arginine was reduced in these patients. Mainly due to elevated basal plasma concentration transfer of methionine was elevated in CT and HD. In dialysis patients transfer of isoleucine, tryptophan, glycine and serine was increased. Despite variations of absolute values of clearance between the two groups investigated relative clearance rates of amino acids were similar because of a uniform increase of clearance of about 37% in HD compared to CT (p less than 0.001). Results indicate that the elimination of parenterally administered amino acids is grossly altered in uremia and that in patients on CT and HD a uniform elimination pattern can be observed.","PeriodicalId":75931,"journal":{"name":"Infusionstherapie und klinische Ernahrung","volume":"13 6","pages":"262-7"},"PeriodicalIF":0.0,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000222158","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14233586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

[Effect of L-carnitine on post-stress metabolism in surgical patients]. 左旋肉碱对手术患者应激后代谢的影响

Infusionstherapie und klinische Ernahrung Pub Date : 1986-12-01

W Heller, H E Musil, G Gaebel, V Hempel, W Krug, H J Köhn

{"title":"[Effect of L-carnitine on post-stress metabolism in surgical patients].","authors":"W Heller, H E Musil, G Gaebel, V Hempel, W Krug, H J Köhn","doi":"","DOIUrl":"","url":null,"abstract":"The positive influence of L-carnitine administration on postaggression metabolism was investigated. Clinical examinations were executed on three groups of patients K1, K2, K3). Comparable surgical operations like stomach- and intestinal- resections were performed on these groups of patients. During the first three days after operation a nutritional diet (parenteral, standardized hypocaloric) with (K2: 2 g; K3: 4g) and without L-carnitine (K1) was given. The effects of L-carnitine administration were evaluated by the following parameters: free fatty acids (FFS), triglycerides (TG), beta-hydroxybutyric acid (beta-OH-BS), acetacetate (ACAC), blood sugar (BZ), insulin (INS), lactate (LAK), pyruvate (PYR), total protein (GE), cholinesterase (CHE), urea production rate (PU), nitrogen of alpha-aminogroups (alpha-AN), nitrogen balance (NB), catabolic index (KI), BUN-Creatinine-quotient (B/K), total carnitine (GC), free carnitine (FC), acetyl carnitine (AC) and also the ratio between acetyl carnitine and free carnitine (AC/FC) in serum and urine. The results show no statistical significance. But they could lead to the following conclusions: Carnitine obviously reduces the insulin resistance. But it does not influence the post-operative perturbation of glucose-utilization. Carnitine reinforces the utilization of long chain fatty acids and thus improves the energy conversion. Carnitine leads to an earlier positive nitrogen balance. By giving 4 g of carnitine a day, already after three days a repletion of tissue deposits is possible, and a dose dependence for carnitine administration exists for the utilization of long chain fatty acids and the repletion of tissue deposits.","PeriodicalId":75931,"journal":{"name":"Infusionstherapie und klinische Ernahrung","volume":"13 6","pages":"268-76"},"PeriodicalIF":0.0,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14234276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0